MeRT System

by Wave Neuroscience  · Based in United States → — Unlocking precision neuroanalytics
Neurology Physical Medicine & Rehab Psychiatry
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Overview

The MeRT (Magnetic e-Resonance Therapy) System by Wave Neuroscience is a medical AI tool that integrates quantitative electroencephalograms (qEEG) and electrocardiograms (ECG) with personalized transcranial magnetic stimulation (TMS) protocols. It is designed to analyze an individual’s brainwave activity and heart rhythm to identify areas of neural dysregulation.

The MeRT System is FDA-cleared for the adjunctive treatment of adult patients suffering from Post-Traumatic Stress Disorder (PTSD). While the equipment used in MeRT is FDA-cleared for Major Depressive Disorder and Obsessive-Compulsive Disorder, MeRT itself is also explored off-label for conditions such as Traumatic Brain Injury (TBI), Autism Spectrum Disorder (ASD), anxiety, and sleep disorders.

In a clinical workflow, the MeRT process typically involves four steps:

  • Evaluation: A 10-minute qEEG and EKG recording is performed to gather data on brainwave frequencies, heart rate, and brain-heart coherence.
  • Analysis and Protocol: The recorded data is analyzed using proprietary algorithms to develop a personalized treatment plan that targets specific brain regions and frequencies for stimulation.
  • Treatment Delivery: Daily rTMS sessions are conducted, typically lasting around 30-45 minutes, with magnetic stimulation applied for brief intervals.
  • Progress Evaluation: Sequential qEEG and EKG recordings are taken periodically to monitor progress and allow for adjustments to the treatment protocol.

Notable capabilities of the MeRT System include its personalized approach to neuromodulation, where treatment parameters are tailored to an individual’s unique electrophysiological characteristics rather than using a one-size-fits-all protocol. This aims to restore and optimize brainwave activity and enhance neural communication.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Individualized EEG/EKG analysis
  • AI-augmented biomarker assessment
  • Personalized Transcranial Magnetic Stimulation (TMS) protocols
  • Non-invasive treatment
  • Drug-free approach
  • Cloud-based platform for brainwave processing
  • Digital brain image conversion to easy-to-interpret reports
  • Comparison of brain activity to normative EEG databases
  • Identification of disruptions in Default Mode Network
  • EEG-guided stimulation

Use Cases

  • Post-Traumatic Stress Disorder (PTSD)
  • Depression and Treatment-Resistant Depression
  • Traumatic Brain Injury (TBI) and Post-Concussive Syndrome
  • Autism Spectrum Disorder (ASD)
  • Anxiety and Attention Problems
  • Sleep Disorders

What Physicians Need to Know

Therapeutic Modality
MeRT (Magnetic e-Resonance Therapy) is a non-invasive, drug-free form of brain stimulation that uses gentle magnetic waves and carefully measured magnetic pulses to influence brain activity. It is a personalized form of repetitive transcranial magnetic stimulation (rTMS) guided by quantitative electroencephalogram (qEEG) and electrocardiogram (EKG) data. Unlike traditional TMS, MeRT protocols are adjusted over time based on measured brainwave activity and ongoing progress evaluation, rather than a fixed protocol.
Crisis Detection & Escalation
MeRT is not a crisis intervention tool. Individuals in crisis or contemplating suicide are advised to seek immediate help by calling or texting 988.
Outcome Measurement
Clinicians monitor progress through markers such as sleep quality, attention, emotional stability, and overall quality of life. Sequential qEEG and EKG recordings are taken every 9-10 treatments to monitor progress, assess changes in brainwave activity, and track results. Progress is also measured using third-party neurocognitive assessments, instruments, and questionnaires. Many patients report improvements in sleep, relaxation, concentration, focus, memory, mood, stress management, attention span, sociability, motivation, and self-confidence.
Provider Dashboard
The MeRT process involves a comprehensive evaluation, including neurological history, symptom review, and EEG-based brain mapping. The brainwave recording is sent to a cloud platform where it is processed against a database of over 60,000 brainwave recordings. This generates an easy-to-interpret report with insights and age/gender-matched comparisons, which clinicians use to generate a patient-specific care protocol and track progress.
Cultural Sensitivity
While the provided information does not explicitly detail MeRT's cultural sensitivity features, effective mental health treatment generally requires a thorough understanding of the culture and language of diverse populations, including considerations for age, race, ethnicity, gender identity, sexual orientation, and disability. Culturally sensitive programs should consider diverse language needs, refugee or migrant status, and socio-economic circumstances.
Physician Tip

MeRT offers a personalized approach to neuromodulation, utilizing EEG/EKG data to tailor TMS protocols. It is FDA-cleared for PTSD, and used off-label for conditions such as depression, anxiety, TBI, autism, and sleep disorders. Physicians should note that MeRT is not a crisis intervention tool. Ongoing monitoring with qEEGs allows for protocol adjustments based on the patient's neurological state. While generally well-tolerated, mild headaches or scalp sensitivity are common initial side effects. The risk of seizure is very low, but patient screening for medical conditions or implants is crucial.

MeRT integrates EEG and EKG diagnostics with an FDA-cleared TMS device to deliver personalized brain stimulation. The system leverages specialized software to analyze brainwave data and generate customized treatment protocols. It can be used alongside therapy and medication management for comprehensive, coordinated care. The MeRT system has achieved FDA clearance for PTSD and integrates seamlessly with platforms like neurocare Apollo TMS.

Details

Category Mental & Behavioral Health AI, Neurology AI
Pricing Paid
  • Initial qEEG and Physician Consultation: $500; MeRT Week 1 & Week 2 with 2nd qEEG: $2000; MeRT Week 3 & Week 4 with 3rd qEEG: $2500; MeRT Week 5 & Week 6 with 4th qEEG: $2500; Additional weeks (if needed): $1250 per week
DeploymentOn-premise (in-clinic therapy)
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated

The MeRT System received FDA Breakthrough Device designation in 2024 and was granted FDA clearance for the treatment of Post-Traumatic Stress Disorder (PTSD) in June 2026. It is the first personalized, biomarker-guided neuromodulation technology to receive FDA clearance for PTSD.
Integrations
EHR Not specified
Specialties Neurology, Physical Medicine & Rehab, Psychiatry

Ratings & Reviews

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Clinical Value
Ease of Use
Integration
Support & Docs
Value for Money

Press & Coverage

Patient Care Online
FDA Clears Wave Neuroscience MeRT System for PTSD - Patient Care Online
The FDA has cleared Wave Neuroscience's Magnetic EEG-guided Resonance Therapy (MeRT) system for post-traumatic stress disorder (PTSD), marking the first FDA clearance for a personalized, biomarker-guided neuromodulation platform in this indication.
2026-06
McGovern Medical School - UTHealth Houston
MeRTu00ae Receives FDA Clearance for PTSD: A New Step Toward Personalized Neuromodulation | McGovern Medical School - UTHealth Houston
Wave Neuroscience's MeRT System has received FDA clearance for PTSD, representing a significant advancement for personalized brain stimulation by combining EEG, ECG, and individualized TMS protocols.
2026-07
PR Newswire
Wave Neuroscience Announces FDA Clearance of MeRTu00ae for PTSD - PR Newswire
Wave Neuroscience announced FDA clearance for its MeRT System for PTSD, establishing it as the first personalized, biomarker-guided neuromodulation technology to receive such clearance for this condition.
2026-06
Wave Neuroscience
MeRT System receives FDA clearance for Post-Traumatic Stress Disorder (PTSD).
Wave Neuroscience proudly announced the FDA clearance of its MeRT System for adults with PTSD, highlighting it as a significant milestone for personalized, EEG-guided neuromodulation.
2026-06
Texas A&M University
Texas A&M Health and Wave Neuroscience Announce FDA Clearance of MeRT for PTSD
Texas A&M Health and Wave Neuroscience partnered to announce the FDA clearance of the MeRT System for PTSD, a personalized, biomarker-guided neuromodulation platform.
2026-07
EIN Presswire
MagVenture Announces FDA Clearance of Wave Neuroscience's MeRTu00ae System for PTSD, delivered on MagVentureu00ae Technology - EIN Presswire
MagVenture announced that the FDA has granted clearance for Wave Neuroscience's MeRT system for the adjunct treatment of PTSD in adult patients, utilizing MagVenture TMS systems.
2026-06
EurekAlert!
New FDA clearance gives PTSD patients more precise, effective treatment options
New FDA clearance for the MeRT System, developed by Wave Neuroscience in collaboration with Texas A&M Health, offers more precise and effective treatment options for PTSD patients.
2026-08
BioSpace
neurocare and Wave Neuroscience partner to expand patient access to FDA-Cleared MeRTu00ae therapy for PTSD on the Apollo TMS Therapy System - BioSpace
Neurocare Group AG and Wave Neuroscience announced a strategic collaboration to expand patient access to the FDA-cleared MeRT therapy for PTSD, which will be delivered on the neurocare Apollo TMS Therapy System.
2026-09

Videos

Product demos, reviews, and walkthroughs for MeRT System.

View all on YouTube

Frequently Asked Questions

The MeRT system uses AI to analyze quantitative electroencephalogram (qEEG) data, identifying specific brainwave abnormalities associated with various mental health conditions. This AI-driven analysis helps in personalizing treatment protocols by targeting dysfunctional neural networks, aiming to optimize the therapeutic effect of transcranial magnetic stimulation (TMS) or other neuromodulation techniques.
Physician compliance involves adherence to specific training protocols for qEEG interpretation and MeRT system operation, as well as ongoing patient monitoring and data submission for treatment efficacy tracking. Patient compliance typically includes consistent attendance for scheduled treatment sessions and reporting any changes in symptoms or medication, which are crucial for optimizing treatment outcomes.
Established alternatives include traditional TMS, electroconvulsive therapy (ECT), pharmacotherapy, and psychotherapy. While these methods have proven efficacy, MeRT differentiates itself by using individualized qEEG data to guide targeted neuromodulation, potentially offering a more personalized and precise approach compared to the broader application of traditional TMS or systemic effects of medication.
The pricing structure for the MeRT system can involve significant upfront costs for equipment acquisition, along with ongoing expenses for consumables, software licenses, and maintenance. This can influence patient access due to out-of-pocket costs, as insurance coverage for MeRT and similar advanced neuromodulation therapies can vary widely and may not be fully comprehensive.
Current limitations of the MeRT system may include its primary focus on conditions responsive to neuromodulation, such as depression, anxiety, and PTSD, with less established efficacy for certain severe or complex psychiatric disorders. It may not be recommended for patients with specific contraindications to TMS, such as a history of seizures or implanted metallic devices in the head.
The MeRT system is designed to comply with HIPAA and other relevant data privacy regulations, employing robust encryption and secure data storage protocols for all patient qEEG and treatment data. This ensures the confidentiality and integrity of sensitive health information, minimizing the risk of unauthorized access or breaches.
Physicians typically undergo specialized training programs that cover the theoretical underpinnings of qEEG, practical application of the MeRT system, and interpretation of brainwave data to develop personalized treatment plans. Certification often involves demonstrating proficiency in these areas, ensuring competent and safe operation of the technology.

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Suggest an Edit → | Last Verified: 2026-09-23 | First Added: 2026-09-23
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