Methinks NCCT Stroke

by Methinks Software S.L.  · Based in Spain → — Unlocking life-saving stroke treatments by leveraging AI on the simplest imaging methods.
Emergency Medicine Neurology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

Methinks NCCT Stroke is an advanced artificial intelligence (AI) software designed to enhance the capabilities of non-contrast computed tomography (NCCT) for rapid and precise stroke triage. It is the first and only software on the market capable of detecting suspected Large Vessel Occlusions (LVOs), including more distal occlusions like those in the M2 segment of the middle cerebral artery (MCA), as well as intracranial hemorrhages (ICH), directly from routine NCCT scans.

This FDA-cleared solution aims to significantly shorten the time to treatment and improve patient outcomes by providing advanced LVO detection to hospitals worldwide, including those with limited imaging resources or without contrast CT capabilities. The software delivers superior accuracy, reducing false-negative errors by nearly 50% compared to other NCCT LVO triage tools.

Methinks NCCT Stroke is uniquely integrated into Microsoft Teams, enabling real-time image sharing and clinical collaboration across stroke teams on a secure platform. It also integrates smoothly into Picture Archiving and Communication Systems (PACS) and existing hospital workflows, supporting faster decisions, improved coordination, and optimized stroke workflows.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Detects Large Vessel Occlusions (LVOs) on NCCT scans
  • Detects Intracranial Hemorrhages (ICH) on NCCT scans
  • Detects distal occlusions (e.g., MCA-M2 segment)
  • Integrates with Microsoft Teams for real-time image sharing and collaboration
  • Integrates with PACS and hospital workflows
  • Provides workflow triage and notification prioritization
  • Reduces false-negative errors by nearly 50% compared to other NCCT LVO triage tools
  • AI-enhanced decision-making for stroke assessment
  • Deployable in any hospital with a standard CT scanner
  • Mobile app for AI alerts and team coordination

Use Cases

  • Accelerating stroke treatment with AI-enhanced decision-making
  • Early detection and diagnosis of acute ischemic stroke
  • Triage and prioritization of stroke patients in emergency settings
  • Improving patient outcomes by reducing time to treatment
  • Enabling advanced LVO detection in hospitals with limited imaging resources
  • Real-time clinical collaboration among stroke teams

What Physicians Need to Know

Stroke Detection Speed
Provides early, rapid, and precise triaging of acute stroke patients. Average time to notification for Intracranial Hemorrhage (ICH) and Large Vessel Occlusion (LVO) on Non-Contrast CT (NCCT) is 1 minute and 27 seconds. For LVO on CT Angiography (CTA), the average notification time is 6 minutes and 36 seconds. The AI tool helps reduce door-to-decision times and can significantly reduce interpretation time in acute settings.
Brain CT Analysis
Analyzes Non-Contrast Computed Tomography (NCCT) and Computed Tomography Angiography (CTA) images of the head. It detects Large Vessel Occlusions (LVO) and Intracranial Hemorrhages (ICH) on NCCT scans, and LVOs on CTA scans. The software is capable of detecting both hyperdense and non-hyperdense LVOs, including distal occlusions up to the M2 segment of the middle cerebral artery. It can also estimate initial core volume on NCCT, which is associated with clinical outcomes in acute ischemic stroke.
Large Vessel Occlusion Detection
Detects LVOs on both NCCT and CTA images. For NCCT LVO detection, studies show sensitivity ranging from 75% to 87.2% and specificity from 83% to 87.7%. For CTA LVO detection, it demonstrates high sensitivity (98.2%) and specificity (91.6%). The tool can detect proximal (ICA, MCA-M1) and more distal (MCA-M2) LVOs, reducing false-negative errors by nearly 50% compared to other NCCT LVO triage tools.
Triage Prioritization Speed
Designed to optimize stroke triage and reduce time to treatment by providing rapid alerts. The system aims to accelerate the process, recognizing that even a 15-minute delay can significantly impact patient outcomes.
ASPECTS Score Automation
While not explicitly automating ASPECTS scores, the Methinks Ischemia algorithm for NCCT can estimate initial core volume, which is capable of predicting favorable outcomes even in patients with a favorable ASPECTS score and appears superior to ASPECTS in late window patients.
Mobile Notification System
Features a cloud-based communication system integrated with Microsoft Teams. It provides instant AI alerts to clinicians when on call, facilitates real-time image sharing, and enables clinical collaboration through chat, audio, and video calls within a secure platform.
Physician Tip

Methinks NCCT Stroke serves as a valuable AI-driven assistant for stroke triage and decision support, working in parallel with standard clinical workflows. It is particularly beneficial in settings with limited access to advanced imaging, as it can detect critical stroke indicators (LVOs and ICH) from readily available NCCT scans. Physicians should utilize the rapid alerts and comprehensive image analysis to expedite treatment decisions, facilitate inter-hospital coordination, and potentially improve patient outcomes by reducing time to intervention. It's important to remember that the software is a triage and notification system, not a replacement for a physician's diagnostic expertise.

Methinks NCCT Stroke is seamlessly integrated with Microsoft Teams, allowing for secure team communication, real-time alerts, and collaborative image review without requiring additional applications. Results are designed to integrate smoothly into existing Picture Archiving and Communication Systems (PACS) and hospital workflows. The solution is available via the Microsoft Azure Marketplace, ensuring secure installation and payment. Strategic partnerships, such as with Medtronic, aim to further streamline connectivity between stroke centers and regional hospitals.

Details

Category Neurology AI, Radiology & Imaging AI, Triage & ER/ICU AI
Pricing Contact for pricing
DeploymentCloud-based, On-premise (integrates with hospital systems)
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Yes AI-estimated

Methinks NCCT Stroke received FDA 510(k) clearance on July 1, 2025, for detecting suspected Large Vessel Occlusions (LVOs) and intracranial hemorrhages (ICH) on non-contrast CT scans. It is noted as the first and only LVO detection software capable of detecting LVOs up to the MCA-M2 level using NCCT.

Integrations
EHR Not specified
Specialties Emergency Medicine, Neurology, Radiology

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Press & Coverage

NeuroNews International
Methinks AI receives US FDA 510(k) clearance for NCCT Stroke software - NeuroNews
Methinks AI announced on July 1, 2025, that its non-contrast computed tomography (NCCT) Stroke software received 510(k) clearance from the US FDA. This software is designed to detect suspected large vessel occlusions (LVOs) and intracranial hemorrhages (ICHs) with high precision, including distal occlusions in the M2 segment of the middle cerebral artery.
2025-07
Methinks AI Press Release
Methinks AI Secures Second FDA Clearance, Expanding its Stroke Detection Solution to Contrast Imaging
On October 9, 2025, Methinks AI announced its second FDA 510(k) clearance for Methinks CTA Stroke, an AI-based solution for detecting large vessel occlusions using CT Angiography. This builds upon the earlier success of Methinks NCCT Stroke, offering a comprehensive stroke triage platform compatible with both NCCT and CTA imaging.
2025-10
NeuroNews International
Methinks expands stroke detection solution into contrast imaging with second US FDA clearance - NeuroNews
Methinks received its second FDA 510(k) clearance in October 2025 for its CTA Stroke software, following the July 2025 clearance of Methinks NCCT Stroke. These combined solutions provide a comprehensive stroke triage platform for both NCCT and CTA imaging, suitable for various healthcare settings.
2025-10
FDA.gov
Methinks Software S.L. Claudia Carbonell Senior QA/RA Manager Methinks Software, S.L. Pier 01, Plau00e7a Pau Vila 1, Office 2D2 - accessdata.fda.gov
This FDA 510(k) summary document, dated June 16, 2025, details the Methinks NCCT Stroke device, a radiological computer-assisted triage and notification software. It processes Non-Contrast Computed Tomography (NCCT) images to prioritize suspected Intracranial Hemorrhage (ICH) and Large Vessel Occlusion (LVO) cases.
2025-06
Innolitics
2025 Year in Review: Cardiology AI/ML SaMD 510(k) Clearances - Innolitics
Innolitics' 2025 review of cardiology AI/ML SaMD 510(k) clearances lists Methinks Software S.L.'s Methinks NCCT Stroke with a clearance date of June 16, 2025.
2026-01
AI for Radiology
Methinks NCCT Stroke | Methinks Software S.L. radiology AI profile
This profile confirms Methinks NCCT Stroke as an FDA-cleared radiology AI listing for CT/CTA, providing details on its workflow and buyer-fit notes.
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Videos

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Frequently Asked Questions

Methinks NCCT Stroke is an AI-based software that analyzes non-contrast CT scans to detect suspected Large Vessel Occlusions (LVOs) and intracranial hemorrhages (ICHs). It integrates seamlessly with PACS and Microsoft Teams, providing real-time notifications to streamline stroke triage and facilitate rapid communication among stroke teams.
Yes, Methinks NCCT Stroke received FDA 510(k) clearance in July 2025 for detecting suspected LVOs and ICHs using NCCT imaging. This clearance signifies its safety and effectiveness as a radiological computer-aided triage and notification system, intended to assist trained physicians in workflow prioritization.
Methinks NCCT Stroke is notable for being the only FDA-cleared software capable of detecting more distal LVOs, such as those in the MCA-M2 segment, directly from NCCT scans, which traditionally has limitations for such detections. While other AI solutions like RapidAI, Viz.ai, and Brainomix exist, Methinks aims to expand access to advanced stroke assessment using the widely available NCCT.
While specific pricing details are not publicly disclosed in the search results, Methinks emphasizes providing an accessible triage tool at an 'affordable price' to help manage healthcare costs. Hospitals would typically integrate such AI solutions into their operational budgets, and reimbursement for AI-assisted diagnostics is an evolving area.
Methinks NCCT Stroke's sensitivity for LVO detection on NCCT is lower compared to CTA-based tools, and it does not analyze posterior circulation or other anterior circulation areas beyond ICA and MCA M1/M2. It is a triage and notification system, not a primary diagnostic device, meaning clinicians remain responsible for final image review and diagnosis.

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More from Methinks Software S.L.

Methinks CTA Stroke
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Neurology AI
Methinks CTA Stroke is an FDA-cleared AI software that accurately detects suspected large vessel occlusions (LVOs) from CTA scans, including distal occlusions, with high sensitivity and specificity. It integrates with hospital systems and Microsoft Teams for real-time stroke triage and team coordination.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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