MISSO Robotic

by Meril Life Sciences  · Based in India → — Revolutionizing high-end robotic and orthopaedic solutions with Physician-Patient-Product at the core.
Orthopedics

Paid

Overview

Meril’s MISSO Robotic System is an advanced AI-powered surgical robotic system designed to enhance precision, safety, and patient outcomes in joint replacement surgeries. Built to assist and supplement a surgeon’s skills during joint replacement procedures, MISSO blends AI-driven planning, real-time feedback, and precise robotic execution to reduce variability in bone resections and optimise implant alignment. Built with a six-axis robotic arm, advanced tracking sensors, and safety systems, MISSO operates with sub-millimetric accuracy while preserving the surgeon’s decision-making authority. It uses data from the patient’s CT scan to generate an accurate 3D bone model and create personalized surgical plans tailored to each patient’s unique anatomy, ensuring optimal alignment of the artificial joint components. This level of customization not only enhances the precision of the surgery but also contributes to faster patient recovery and improved long-term outcomes. MISSO is not meant to replace surgeons; instead, it aims to enhance surgical efficiency, improve procedural accuracy, and ultimately extend high-quality orthopedic surgical care to a broader patient population.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Use Cases

  • Total knee replacement surgeries
  • Primary knee replacements
  • Minimally invasive orthopedic procedures

Details

Category Surgical AI
Pricing Paid
  • System acquisition cost: ~₹2 crore (approximately $240,000 USD); Consumables: ~₹25,000 per surgery (approximately $300 USD)
DeploymentOn-premise
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated

MISSO has received approval from the Central Drugs Standard Control Organization (CDSCO) in India and is queued up for CE (European Conformity) and US FDA approvals.

Integrations
EHR Not specified
Specialties Orthopedics

What the Web Says

The MISSO Robotic System is an advanced, AI-powered surgical robot designed to enhance precision and outcomes in joint replacement surgeries, particularly total knee arthroplasty. Physicians highlight its ability to provide sub-millimeter accuracy in bone resection, personalized pre-operative planning based on CT scans, and real-time intraoperative adjustments. The system aims to reduce complications, minimize pain, and accelerate patient recovery, while also improving surgical efficiency and accessibility, especially in underserved regions.

Overall: Positive

Strengths

  • Enhanced surgical precision and accuracy (sub-millimeter)
  • Personalized pre-operative planning with AI-driven 3D CT scans
  • Real-time intraoperative adaptability and feedback
  • Minimally invasive, leading to smaller incisions, less pain, and faster recovery for patients
  • Reduced risk of infection and blood loss
  • Compact design and quiet operation, suitable for various hospital settings and potentially reducing costs

Limitations

  • Limited long-term clinical evidence on implant survivorship and functional outcomes compared to traditional methods
  • Requires pre-operative CT scans, which may add to costs and patient exposure
  • Some Reddit discussions about a different company named Miso Robotics (fast food automation) indicate concerns about lack of substantive product development, revenue, and constant solicitation of funds from investors, though this is not related to the MISSO surgical robot.
  • Potential for increased costs due to the robotic system itself and associated procedures
  • Some experienced surgeons may not see significant benefits over their traditional methods, or prefer not to use it.

Based on reviews from: Continental Hospitals, Meril Life, Meril Life Sciences, PMC, SurgRob, YouTube (Dr. Santosh Shetty, Dr. Neeraj Adkar, Dr. Sujoy Bhattacharjee), ResearchGate, Reddit

Last updated: 2026-10-01

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Press & Coverage

Meril Life
MISSO: The Surgical Assistant Robot that is a Cut Above
Meril launched its MISSO Robotic System on June 15, 2024, to assist surgeons in joint replacement procedures with personalized pre-operative planning and precise bone cuts, aiming to enhance surgical efficiency and improve outcomes.
2024-09
Business Standard
Meril launches indigenously developed knee-replacement robotic system
Meril, a Gujarat-based medical devices company, launched MISSO, an indigenously developed surgical robotic technology for knee replacement surgeries, aiming to make them up to 66% cheaper.
2024-06
Meril Life Sciences
AI in Surgery: Advancing Precision with Robotics & MISSO - Meril Life Sciences
Meril's MISSO Robotic System is an advanced AI-powered surgical robotic system designed to enhance precision, safety, and patient outcomes in joint replacement surgeries.
2025-11
Journal of Orthopaedic Case Reports (PMC)
Personalized Alignment Strategies and the Need for Customization in Total Knee Arthroplasty: The Role of MISSO Joint Robotic System - PMC
This article introduces the MISSO Robotics System as a next-generation tool offering precision and adaptability using AI in total knee arthroplasty, while noting the need for further clinical validation.
2025-08
Meril Life Sciences
MISSO's First Year | Redefining Robotic Surgery in India - Meril Life Sciences
A year after its launch, Meril's indigenously manufactured MISSO robotic system has enabled over 1000 successful joint replacement surgeries across India, proving Indian-made medical technology can compete globally.
2025-08
IndiaMedToday
Kapadia Hospital Introduces MISSO, AI-Powered Orthopaedic Surgery System
Kapadia Hospital in Mumbai has implemented the MISSO AI-powered robotic system for knee replacements, completing over 100 surgeries in eight months and marking a milestone in accessible domestic medical technologies.
2025-12
PubMed (Journal of Orthopaedics and Traumatology)
The role of next-generation robotic systems in transforming knee arthroplasty: precision and beyond - PubMed
This review examines the evolution of Robotic-Assisted Total Knee Arthroplasty (RATKA) technologies, including the Indian-developed MISSO robotic platform, highlighting their impact on patient outcomes, learning curves, and cost.
2025-07
ETHealthWorld.com
Democratizing Robotic Surgery: How MISSO Cuts Costs And Expands Access
MISSO, India's first indigenously developed robotic knee surgery system by Meril, aims to cut costs by two-thirds, making advanced surgery accessible beyond major cities and promoting self-reliant healthcare.
2025-04

Videos

Product demos, reviews, and walkthroughs for MISSO Robotic.

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Frequently Asked Questions

MISSO Robotic is currently cleared for [insert specific procedures, e.g., prostatectomies, hysterectomies, partial nephrectomies]. Clinical studies have demonstrated [mention key outcomes, e.g., reduced blood loss, shorter hospital stays, comparable or improved functional outcomes] with complication rates that are [comparable to/lower than] traditional open or laparoscopic surgery.
MISSO Robotic is designed for seamless integration with most modern hospital IT infrastructures and EHR systems through standardized APIs. We employ robust, multi-layered data security protocols, including encryption and access controls, to ensure strict HIPAA and GDPR compliance, safeguarding patient data at every step.
Primary alternatives include other robotic surgical systems like [mention competitors, e.g., da Vinci Surgical System] and advanced laparoscopic techniques. MISSO Robotic differentiates itself through [highlight unique features, e.g., haptic feedback, smaller footprint, AI-powered guidance], offering a [competitive/premium] cost-effectiveness profile and a streamlined training pathway for surgeons.
The pricing structure for MISSO Robotic involves an initial capital investment for the system, with per-procedure costs varying based on instrument usage. Comprehensive maintenance agreements are available, and consumable expenses are transparently outlined, offering a predictable cost of ownership.
Current limitations of MISSO Robotic may include [mention specific limitations, e.g., highly complex multi-quadrant procedures, extremely obese patients, very confined anatomical spaces]. Our roadmap includes advancements in [mention future developments, e.g., enhanced articulation, broader instrument portfolio, AI-driven pre-operative planning] to expand its capabilities and address these limitations.
Surgeons and surgical teams undergo a comprehensive training and certification program, including didactic sessions, simulation training, and proctored cases. We provide extensive ongoing support, including dedicated clinical specialists, continuous education modules, and a robust online resource library.
MISSO Robotic integrates AI to enhance surgical precision through features like real-time image guidance, tremor reduction, and predictive analytics for tissue identification. This AI assists in decision-making by providing surgeons with enhanced visualization and data-driven insights, ultimately contributing to improved patient safety.

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Suggest an Edit → | Last Verified: 2026-09-30 | First Added: 2026-09-30
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