PrecisePK

by PrecisePK  · Based in United States →A Leading Bayesian Therapeutic Drug Monitoring Software for Model-Informed Precision Dosing (MIPD)
Critical Care Pediatrics

Documentation Provided

Overview

PrecisePK is a cutting-edge Bayesian Therapeutic Drug Monitoring (TDM) software designed for Model-Informed Precision Dosing (MIPD). It leverages advanced AI and Bayesian algorithms to accurately calculate precise dosing regimens and predict drug levels. This empowers pharmacists and clinicians to make timely, data-driven dosing recommendations, ultimately optimizing patient outcomes and enhancing medication safety across various clinical settings.

The platform offers an industry-leading Vancomycin AUC dosing tool, fully compliant with the 2020 ASHP/IDSA Vancomycin Guidelines. A key strength of PrecisePK is its adaptability, allowing for precise adjustments for diverse patient populations, including neonates, pediatrics, adults, obese patients, critically-ill individuals, and those post-cardiac surgery. Clinicians can select the most appropriate Bayesian prior models to ensure personalized and effective treatment strategies.

Beyond Vancomycin, PrecisePK includes comprehensive drug modules for monitoring other medications requiring pharmacokinetic oversight. It features real-time monitoring capabilities and robust data-driven analytics, providing valuable insights into patient responses. A notable addition is its Acute Kidney Injury (AKI) Prediction Tool, which further supports proactive patient management and risk mitigation.

PrecisePK is built on a foundation of strong compliance and security, holding SOC2, ISO/IEC 27001:2013, HIPAA, and GDPR certifications. Its user-friendly interface is designed for minimal training, facilitating quick adoption by medical and pharmaceutical professionals. With active partnerships in over 100 institutions and across 10+ countries, PrecisePK is a trusted global solution for precision dosing.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Bayesian Precision Dosing
  • Vancomycin AUC Dosing (2020 ASHP/IDSA Compliant)
  • Acute Kidney Injury (AKI) Prediction Tool
  • Real-time Monitoring
  • Data-driven Analytics
  • Multiple Drug Modules
  • Adjustments for Special Populations (neonatal, pediatric, adult, obese, critically-ill, post-cardiac surgery)
  • Flexible Bayesian Prior Model Selection
  • User-friendly Interface
  • HL7 Integration

Use Cases

  • Therapeutic Drug Monitoring (TDM)
  • Precision Dosing Regimen Calculation
  • Vancomycin Area Under the Curve (AUC) Dosing
  • Acute Kidney Injury (AKI) Management
  • Pharmacokinetic Monitoring for Various Medications
  • Clinical Research Support

What Physicians Need to Know

Evidence Base
PrecisePK's drug models are developed by in-house pharmacists who compile evidence-based, clinically-validated PK/PD literature and extensive research from well-validated clinical trials. The platform is fully compliant with the IDSA/ASHP Vancomycin 2020 guidelines and utilizes a wide library of clinical guidelines and references to build drug models for diverse patient populations, including pediatrics, neonates, obese, critically ill, and those with kidney injury. Population models are derived from peer-reviewed, reputable literature to establish Bayesian priors. PrecisePK also integrates with Sanford Guide for seamless access to concise clinical guidelines for anti-infective agents. The system covers over 20 medications across therapeutic areas such as infectious diseases, oncology, cardiology, and neurology, with recent additions including Methotrexate, Cyclosporine, and Infliximab.
Clinical Validation Studies
PrecisePK combines extensive research from well-validated clinical trials with real-time patient data. It has been validated by a third-party for providing the most accurate and least biased vancomycin AUC results. A study published in Pharmacotherapy by Turner, R.B., et al., demonstrated PrecisePK's superior accuracy in predicting Vancomycin AUC in critically ill patients. Additionally, a small study (n=19) found PrecisePK to be the most accurate among five Bayesian dosing software programs for vancomycin AUC estimation in critically ill American patients. The Bayesian dosing approach used by PrecisePK has shown financial benefits, including reduced nephrotoxicity and shorter hospitalization durations.
Alert Fatigue Management
PrecisePK features a comprehensive alert system designed to minimize toxicity. It provides toxicity warnings and alerts when the Area Under the Curve (AUC) is outside the recommended range or if a patient is approaching potential ototoxicity. These clinically relevant alerts aim to guide dosing adjustments and promote safer drug therapy. By providing real-time data recording, computation, and monitoring, Bayesian tools like PrecisePK help eliminate guesswork in daily decision-making, which can contribute to mitigating pharmacist burnout by reducing uncertainty.
Drug Interaction Checking
PrecisePK offers a dedicated 'Drug Interaction Checker' tool. This tool enables users to build a patient medication list, flag common drug interactions, review overlapping toxicities, and identify laboratory markers that may require monitoring. It also generates a structured evidence bundle for interpretation and considers additional drug factors such as concomitant medications.
Guideline Update Frequency
PrecisePK is updated regularly, typically once to twice a month, to ensure it remains at the forefront of pharmacokinetics software. Web App users are notified of new updates upon logging in, with detailed information available on the Changelog page. The system is designed to quickly incorporate newly validated pharmacokinetic parameters from research. Additionally, the integrated Sanford Guide content is updated daily.
Clinical Workflow Integration
PrecisePK is designed for seamless and secure integration into everyday clinical workflows. It offers Electronic Health Record (EHR) integration, including full integration with the Epic EHR platform via the App Orchard Marketplace. This integration allows for the automatic import of medication orders, previous doses, vancomycin levels, and serum creatinine, streamlining patient care. The user-friendly interface facilitates saving patient cases, building upon dosage history, and sharing patient information for improved care coordination. PrecisePK provides unlimited 1-on-1 onboarding training and ongoing technical and clinical support. The Bayesian method's ability to estimate AUC with as little as one serum level also enhances workflow flexibility.
Decision Audit Trail
PrecisePK assists institutions with their yearly audits by analyzing patient population therapeutic statuses, dosing strategies, and incidences of Acute Kidney Injury (AKI). It allows for retroactive comparison against past data to confirm dosing practices and track patient population progress. Admin users have the capability to manage the change history of patient records and review the patient database. The Bayesian tools within PrecisePK continuously record, compute, and monitor data in real time, contributing to a comprehensive audit trail.
Physician Tip

Leverage PrecisePK's Bayesian-guided dosing for individualized and precise medication regimens, especially for narrow therapeutic index drugs like vancomycin and carboplatin, to optimize patient outcomes and minimize toxicity. Utilize the comprehensive alert system for toxicity warnings and out-of-range AUC values, but also exercise clinical judgment, as the system allows for parameter overrides. Integrate the tool into your daily workflow to streamline dosing calculations, access patient history, and collaborate with colleagues. Take advantage of the integrated drug interaction checker to proactively identify potential issues and monitor relevant lab markers. Stay informed about regular updates and new drug models to ensure you are using the most current evidence-based recommendations.

PrecisePK offers robust EHR integration, including full compatibility with Epic via the App Orchard Marketplace, enabling automatic data import for streamlined patient care. It also integrates with the Sanford Guide, providing seamless access to up-to-date infectious disease guidelines directly within the platform. The system supports Single Sign-On (SSO) integration (e.g., OKTA, DUO, InCommon, SecureAuth) for enhanced security and ease of access. PrecisePK's architecture allows for the development of local population models based on a hospital's specific patient data, further refining its precision.

Details

Category Clinical Decision Support & Reference, Lab & Diagnostics, Pharmacology & Dosing AI
Pricing Unknown unknown
Free TrialUnknown
Mobile AppNone
API AvailableUnknown
LanguagesEnglish, Español, 中文, ไทย, 한국어
TrainingUnknown
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated — unknown
SOC 2Unknown AI-estimated
GDPRUnknown AI-estimated
Integrations
EHR Hl7
Specialties Critical Care, Pediatrics

Social Proof

Customersthousands of medical and pharmaceutical professionals, 100+ active partnerships
Notable
UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences

Support & Reliability

Training ProvidedUnknown

What the Web Says

PrecisePK is a leading therapeutic drug monitoring software that utilizes Bayesian model-informed precision dosing, particularly specializing in vancomycin AUC dosing. It is highly regarded by medical and pharmaceutical professionals, including pediatricians, neonatologists, and hospital clinical staff. The software aims to bridge the gap between drug reference guides and precise dosing recommendations by combining research, guidelines, and machine learning algorithms to compute individualized dosing regimens.

Overall: Positive

Strengths

  • Industry-leading vancomycin AUC dosing accuracy, validated by independent research and compliant with 2020 ASHP/IDSA Vancomycin Guidelines.
  • User-friendly interface requiring minimal training, with a visually appealing new version.
  • Flexibility in selecting neonatal, pediatric, and adult models, and adjustment for special populations like obese, critically-ill, and post-cardiac surgery patients.
  • Helps make research more efficient and is a reliable dosing tool for daily vancomycin dosing.
  • Provides real-time monitoring, data-driven analytics for acute kidney injury management, and an AKI prediction tool.
  • Strong user support and comprehensive documentation.

Limitations

  • Pricing information is not readily available and may require a subscription commitment.
  • Primarily focused on vancomycin monitoring, although it offers other drug modules.
  • Some discussions on Reddit indicate a desire for clearer consensus on vancomycin dosing methods despite the software's capabilities.

Based on reviews from: PrecisePK - A Leading Therapeutic Drug Monitoring Software for u200du200dModel-Based Bayesian Precision Dosing, PrecisePK Therapeutic Drug Monitoring Software Review & Analysis | ResearchBuddy, PrecisePK Bayesian Software - GlobalRPH, Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs? - Frontiers, PrecisePK Uses A.I. and Bayesian Dosing to Bridge the Gap between Research and Clinical Care, Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs?, PrecisePK's Bayesian Precision Dosing Solutions Gain Trust of Premier Health System- Setting the Gold Standard for Clinicians in South America - PR Newswire, Model-Informed Precision Dosing Software Tools for Dosage Regimen Individualization: A Scoping Review - PMC, AUC Vancomycin Switch : r/pharmacy - Reddit, Kern Medical Chooses PrecisePK to Provide Bayesian Precision Dosing Solutions

Last updated: 2026-08-07

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Press & Coverage

PrecisePK
PrecisePK Introduces Groundbreaking Drug Models for Bayesian Precision Dosing
PrecisePK launched three new Bayesian precision dosing drug models for Methotrexate, Cyclosporine, and Infliximab, aiming to revolutionize therapeutic drug monitoring and forecasting for transplant and immunosuppressive therapy patients. These models offer enhanced accuracy and reliability in dosage predictions across various conditions.
2024-04
PrecisePK
PrecisePK Partners with Pacific University Oregon to Advance Precision Medicine Research
PrecisePK announced a strategic collaboration with Pacific University Oregon to advance precision medicine research and innovation. This partnership aims to expedite advancements in precision medicine education and research by leveraging state-of-the-art technology.
2024-04
PrecisePK
From burnout to balance: How Bayesian tools reshape pharmacy practice
This article discusses how Bayesian precision dosing tools can help clinical pharmacists combat burnout by streamlining vancomycin AUC dosing workflows and providing confidence in decision-making through real-time data monitoring. These tools integrate with surveillance solutions to optimize patient care and support antimicrobial stewardship.
2024-02
PR Newswire
PrecisePK Pioneers Model-Informed Precision Dosing and Pharmacokinetics Advancements in Argentina with Maza University
PrecisePK partnered with Maza University in Argentina, making it the first institution in the country to acquire their pharmacokinetics software. This collaboration aims to transform pharmacology education and clinical practice by focusing on precision medicine and evidence-based approaches.
2023-12
BioSpace
PrecisePK Redefines Precision Dosing with Academic Integration, Setting New Standards In Therapeutic Drug Monitoring
PrecisePK is expanding its presence in South America by integrating its Bayesian Model-Informed Precision Dosing (MIPD) software into healthcare and educational institutions, including recognition from Chile's Escuela de Quu00edmica y Farmacia. This initiative aims to revolutionize precision drug dosing and elevate clinical standards.
2023-11
PR Newswire
PrecisePK's Bayesian Precision Dosing Solutions Gain Trust of Premier Health System- Setting the Gold Standard for Clinicians in South America
PrecisePK announced a two-year partnership with Clu00ednica Andes Salud Concepciu00f3n in Chile, solidifying its role as a leading Bayesian-based Therapeutic Drug Monitoring (TDM) solution in South America. This collaboration aims to enhance clinical outcomes and patient experiences through personalized precision dosing.
2023-10
PrecisePK
PrecisePK Celebrates 30 Years of Bayesian Precision Dosing Partnership With UC San Diego Health
PrecisePK celebrated 30 years of partnership with UC San Diego Health, highlighting the success of Bayesian precision dosing in improving patient outcomes. The collaboration has focused on enhancing safety in oncology treatments and improving overall survival rates for cancer patients.
2023-08
PrecisePK
PrecisePK Expands Its Global Standing as The Most Trusted Bayesian Dosing Software for South Korea's Health Systems
PrecisePK's Bayesian Model-Informed Precision Dosing (MIPD) software is being implemented in major South Korean health systems, including Chung-Ang University Healthcare System and Asan Medical Center. This expansion solidifies PrecisePK's global presence and its commitment to delivering precision dosing for over 20 medications.
2023-03

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Suggest an Edit → | Last Verified: 2026-05-07 | First Added: 2026-05-07

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