STAR Apollo Mapping System

by Rhythm AI Ltd  · Based in United Kingdom →Navigating the Complexity of Atrial Fibrillation.
Cardiology

Contact vendor for pricing
Regulatory Status Disclosed

Overview

The STAR Apollo Mapping System by Rhythm AI Ltd is an innovative AI-driven medical device designed to revolutionize the treatment of atrial fibrillation (AF). It transforms AF procedures by providing cutting-edge, real-time data analysis from existing electrophysiology (EP) systems. Powered by sophisticated AI algorithms rooted in fundamental electrophysiological principles, STAR Apollo uncovers repetitive patterns within arrhythmias and precisely pinpoints early sites of activation (ESAs) of the heart that are potential drivers of AF.

This breakthrough capability empowers physicians to craft highly personalized treatment plans tailored to each patient’s unique needs, significantly improving the diagnosis and treatment of AF. The system integrates seamlessly into current clinical workflows and is compatible with leading EP mapping systems such as Abbott’s EnSite X EP System and Johnson & Johnson’s CARTO 3 Mapping System.

Rhythm AI Ltd, a UK-based company, focuses on optimizing AF procedures and has received US Food and Drug Administration (FDA) 510k clearance for the commercial launch version of its STAR Apollo Mapping System. The system assists operators in identifying ESAs and Repetitive Patterns of Activation (RPA) during cardiac mapping procedures for AF.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Real-time data analysis from existing EP systems
  • Sophisticated AI algorithms for arrhythmia pattern recognition
  • Identification of Repetitive Patterns of Activation (RPA)
  • Pinpointing Early Sites of Activation (ESA)
  • Enables highly personalized treatment plans
  • Seamless integration into current clinical workflows
  • Summarizes and characterizes AF activation patterns
  • Identifies most frequent AF origin sites
  • Utilizes fundamental principles of electrophysiology
  • Assists in manual annotation of 3D anatomical and electrical maps

Use Cases

  • Optimizing Atrial Fibrillation (AF) procedures
  • Identifying AF origin sites
  • Creating customized AF treatment plans
  • Guiding catheter ablation procedures for AF
  • Used with Pulsed Field Ablation (PFA) or traditional radiofrequency energy delivery systems
  • Analysis of 3D anatomical and electrical maps of human atria

What Physicians Need to Know

ECG/EKG Analysis Capability
The STAR Apollo Mapping System analyzes unipolar intracardiac electrograms collected from compatible electrophysiology (EP) systems in real-time. It uses AI-based algorithms to identify Early Sites of Activation (ESAs) and Repetitive Patterns of Activation (RPAs) within the atria during atrial fibrillation (AF) procedures.
Arrhythmia Detection Accuracy
The system is FDA 510k cleared for use in atrial fibrillation (AF) and is designed to uncover repetitive patterns within arrhythmias and pinpoint early sites of activation that are potential drivers of AF. Early studies have shown improved long-term arrhythmic outcomes in patients with persistent AF when targeting sites identified by STAR Apollo.
Cardiac Monitoring Integration
STAR Apollo Mapping System integrates with existing electrophysiology systems, including Johnson & Johnson's CARTO 3 Mapping System and Abbott's EnSite X EP System (via LiveSyncu2122 function). It analyzes data streamed live from these systems.
Real-Time Alert Capability
The system performs real-time analysis of live data to identify and display heart regions associated with AF and repeating activation patterns. It provides visual cues on a graphical representation of the heart's atrial chamber, highlighting Early Activation Sites (ESAs) and Repetitive Patterns of Activation (RPAs) to guide physicians during ablation procedures.
Physician Tip

The STAR Apollo Mapping System offers electrophysiologists a powerful AI-driven tool to enhance the precision and personalization of atrial fibrillation (AF) ablation procedures, particularly for persistent AF. By providing real-time analysis of intracardiac electrograms to identify early activation sites and repetitive patterns, it can help pinpoint critical drivers of AF that might be challenging to identify with traditional mapping alone. This can lead to more targeted ablation strategies, potentially improving procedural success rates and long-term patient outcomes. Consider its use in complex cases, including redo-ablations or patients with anatomical variations like persistent left superior vena cava (PLSVC), where identifying extra-pulmonary targets is crucial.

The STAR Apollo Mapping System is designed to integrate seamlessly with leading 3D cardiac mapping systems. It has received FDA clearance for compatibility with Johnson & Johnson's CARTO 3 Mapping System and Abbott's EnSite X EP System, utilizing their live data transfer capabilities (e.g., LiveSyncu2122 for EnSite X). The system operates as a software-driven solution on a laptop, processing exported electrogram data from these compatible EP systems.

Details

Category Cardiology AI, Surgical AI
Pricing Contact vendor for pricing
DeploymentIntegrates with existing electrophysiology (EP) systems such as Abbott's EnSite X EP System and Johnson & Johnson's CARTO 3 Mapping System.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

The STAR Apollo Mapping System has received US FDA 510k clearance for its commercial launch version, with expanded compatibility to include Johnson & Johnson's CARTO 3 Mapping System and Abbott's EnSite X EP System.

Integrations
EHR Not specified
Specialties Cardiology

What the Web Says

The STAR Apollo Mapping System, developed by Rhythm AI, is a cardiac mapping system designed to improve the accuracy and efficiency of arrhythmia diagnosis and treatment. Reviews highlight its advanced algorithms and user-friendly interface as key benefits for electrophysiologists. While specific detailed reviews from physicians, healthcare IT, and tech reviewers are not widely available on common platforms like G2 or Capterra, the company's website emphasizes its potential to enhance clinical workflows and patient outcomes.

Overall: Mixed

Strengths

  • Advanced algorithms for precise arrhythmia mapping
  • Potential to improve diagnostic accuracy in complex cases
  • Aims to enhance efficiency in electrophysiology labs
  • User-friendly interface (based on product descriptions)
  • Focus on improving patient outcomes in cardiac care
  • Developed by a company specializing in AI for healthcare

Limitations

  • Limited publicly available detailed physician reviews
  • Lack of independent tech reviewer assessments
  • No readily apparent discussions on Reddit, G2, or Capterra
  • Specific cost information is not publicly available
  • Integration challenges with existing hospital IT infrastructure are unknown
  • Learning curve for new users is not documented in public reviews

Based on reviews from: Rhythm AI official website, General medical technology news outlets (limited mentions), Academic publications (potential for research papers, not direct reviews)

Last updated: 2026-07-19

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Press & Coverage

Rhythm AI
RHYTHM AI announces FDA clearance of the commercial release version of STAR Apollou2122 Mapping System
RHYTHM AI announced FDA 510k clearance for the commercial launch version of its STAR Apollou2122 Mapping System, designed to optimize Atrial Fibrillation (AF) treatment with real-time AI-driven analysis of data from Abbott's EnSiteu2122 X EP System. The company also reported successful first-in-human cases using the updated system.
2024-12
Pharmafile
Rhythm AI's STAR Apollo system receives FDA clearance for atrial fibrillation
Rhythm AI's STAR Apollo Mapping System received 510k clearance from the US FDA for use in atrial fibrillation, now with increased compatibility including Johnson & Johnson's CARTO 3 Mapping System. The system uses AI-based algorithms to identify heart regions associated with AF and repeating patterns, enabling personalized treatment.
2026-02
FirstWord HealthTech
FDA greenlights AI software for mapping irregular heart beats
UK-based Rhythm AI announced that its commercial version of the STAR Apollo Mapping System received 510(k) clearance from the FDA to map atrial fibrillation (AF) patterns, with successful first-in-human use cases reported. The updated software enables real-time analysis of data from standard cardiac mapping systems like Ensite Precision or Ensite X EP.
2024-09
FirstWord HealthTech (Rhythm AI Press Release)
RHYTHM AI: FDA clearance for new STAR Apollou2122 Mapping System
RHYTHM AI announced FDA 510k clearance for its new STAR Apollo Mapping System, expanding compatibility to include the CARTOu2122 3 Mapping System from Johnson & Johnson MedTech. This system uses AI-driven algorithms for real-time analysis of AF procedures, allowing for customized patient treatment plans.
2026-01
Innovations in Pharmaceutical Technology
RHYTHM AI announces FDA clearance of the commercial release version of STAR Apollo Mapping System
RHYTHM AI received FDA 510k clearance for the commercial launch of its STAR Apollo Mapping System, which optimizes AF treatment through real-time AI-driven analysis of data from the EnSite X EP System. The company also confirmed successful first-in-human cases.
2024-09
BioWorld
Growth in AI mapping tools for arrhythmia treatment
Rhythm AI's STAR Apollo mapping system, an AI-based software, recently received U.S. FDA clearance for optimizing Atrial Fibrillation procedures. The article discusses the growing trend of AI mapping tools in arrhythmia treatment, highlighting how STAR Apollo characterizes AF activation patterns to identify origin sites.
2024-10
Rhythm AI
Rhythm AI Appoints Medtech Veteran Mike Dineen as Chief Executive Officer
Rhythm AI, developer of the STAR Apollou2122 Mapping Software, announced the appointment of Mike Dineen as CEO. Dineen's appointment aims to accelerate the company's U.S. rollout and expand physician access, especially with the STAR Apollo system now compatible with both Abbott's EnSiteu2122 X EP System and Johnson & Johnson's CARTOu2122 3 Mapping System.
2026-06
ResearchGate (HeartRhythm Case Reports)
Stochastic Trajectory Analysis of Ranked Signals (STAR) Apollo mapping system approach to treat persistent atrial fibrillation: A case report
This case report details the application of the STAR Apollo mapping system in treating persistent atrial fibrillation, showcasing its ability to identify early sites of activation and repetitive patterns of activation to guide ablation. The study highlights high rates of AF termination and freedom from AF/AT.
2024-05

Videos

Product demos, reviews, and walkthroughs for STAR Apollo Mapping System.

View all on YouTube

Frequently Asked Questions

The STAR Apollo Mapping System integrates with existing 3D cardiac mapping systems, such as Johnson & Johnson's CARTO 3 and Abbott's EnSite X EP System, by analyzing live or exported electrogram data. It processes this data using AI algorithms to identify key activation patterns in real-time, assisting physicians during atrial fibrillation (AF) ablation procedures.
The STAR Apollo Mapping System has received 510k clearance from the US Food and Drug Administration (FDA) for use in atrial fibrillation procedures. While specific HIPAA details are not publicly detailed, as a medical device handling patient data, it is expected to adhere to relevant data privacy regulations. The system operates outside the sterile field, and data transfer is one-way from the compatible mapping system.
The system assists in identifying potential drivers of AF but is not intended for directing treatment or affecting the outcome of any particular arrhythmia. Its clinical significance in identifying areas with intracardiac atrial electrograms for atrial arrhythmias has not been fully established by clinical investigations, and there are no multicenter randomized studies yet. Additionally, it does not aim to elucidate the fundamental mechanism of AF.
The STAR Apollo system works in conjunction with standard 3D cardiac mapping systems like Johnson & Johnson's CARTO 3 and Abbott's EnSite X EP System, which are foundational tools. Other algorithm-based approaches for detecting AF sources exist, often based on phase-mapping or activation mapping. Traditional electro-anatomical mapping methods also serve as a primary approach for AF assessment.
Specific pricing details for the STAR Apollo Mapping System are not publicly disclosed in the available information. Typically, medical device acquisition involves direct negotiation with the manufacturer, Rhythm AI, and pricing can vary based on factors such as institutional size, volume of procedures, and bundled service agreements. Interested healthcare institutions would need to contact Rhythm AI directly for detailed pricing and acquisition information.
The system utilizes advanced AI-based algorithms to analyze real-time or exported electrogram data, identifying repetitive patterns of activation and early sites of activation that are potential drivers of AF. This unique insight empowers physicians to build tailored and targeted treatment strategies, thereby optimizing AF procedures and enabling highly personalized treatment plans for individual patients.

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Suggest an Edit → | Last Verified: 2026-04-19 | First Added: 2026-04-19
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