StrokeViewer Perfusion

by NICo-Lab B.V.  · Based in Netherlands → — AI-powered stroke workflow technology for rapid diagnosis and treatment decisions.
Emergency Medicine Neurology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

StrokeViewer Perfusion, developed by NICo-Lab B.V., is an advanced AI-powered image processing software application designed to revolutionize acute stroke care. Integrated within the broader StrokeViewer platform, it analyzes CT perfusion (CTP) images of the brain to provide quantitative perfusion information for suspected ischemic stroke patients.

The tool generates intuitive and easy-to-read perfusion maps, including TMax (Time to Maximum Contrast Enhancement), CBF (Cerebral Blood Flow), CBV (Cerebral Blood Volume), and Lesion Maps, which identify and quantify core and penumbra volumes. This critical information aids clinicians in evaluating brain tissue viability and making informed decisions about treatment eligibility, particularly for late-window stroke patients who may benefit from thrombectomy.

Beyond perfusion analysis, StrokeViewer offers a comprehensive suite of tools for the entire stroke workflow, including Large Vessel Occlusion (LVO) detection, hemorrhage detection and quantification, collateral assessment, and ASPECT scoring. It supports rapid triaging of stroke patients by automatically analyzing images and sending mobile notifications to stroke teams, enabling quick review and collaboration from any device.

Built on a cloud-native architecture, StrokeViewer Perfusion ensures easy implementation in any hospital without requiring additional hardware, and it integrates with standard reading environments like PACS. The platform is designed to accelerate time to treatment, improve patient outcomes, and facilitate seamless communication within stroke networks.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI-powered CT Perfusion analysis
  • Quantitative perfusion maps (TMax, CBF, CBV)
  • Lesion map for core and penumbra volume quantification
  • Large Vessel Occlusion (LVO) detection
  • Hemorrhage detection and quantification
  • Collateral circulation assessment
  • ASPECTS scoring
  • Mobile notifications for critical findings
  • Remote image review via web-based DICOM viewer
  • Secure chat and screen sharing for team collaboration
  • Cloud-native architecture for easy deployment
  • Integration with PACS and standard reading environments

Use Cases

  • Rapid diagnosis of acute ischemic stroke
  • Determining treatment eligibility for stroke patients
  • Facilitating inter-hospital communication and patient transfers
  • Remote consultation and diagnosis by stroke specialists
  • Optimizing stroke workflow and reducing time to treatment
  • Assessing brain tissue viability for thrombectomy decisions

What Physicians Need to Know

Evidence Base
StrokeViewer Perfusion's algorithms are informed by and align with clinical trials such as DAWN and DEFUSE 3, which expanded treatment eligibility for late-window stroke patients. It utilizes validated DEFUSE 3 thresholds for identifying and quantifying core and penumbra volumes. The platform is CE marked and FDA-cleared, with its perfusion analysis software defining ischemic core as relative cerebral blood flow (rCBF) < 30% and hypoperfused tissue as Tmax > 6 seconds.
Clinical Validation Studies
The CT Perfusion algorithm has received FDA 510(k) clearance, supported by multicenter clinical studies. For Large Vessel Occlusion (LVO) detection, StrokeViewer LVO demonstrated a sensitivity of 91.1% and specificity of 87.0% in a multireader study across U.S. stroke centers. Another study showed sensitivity and specificity for LVO detection similar to advertised values (91-94% sensitivity, 93% specificity) and comparable efficacy to a junior registrar. The automated perfusion software's volumetric and spatial agreement with 24-hour follow-up DWI for ischemic core estimation has been studied, showing moderate agreement comparable to other commercial software.
Alert Fatigue Management
The system provides instant notifications to involved physicians on mobile devices or via email when critical findings, such as suspected large vessel occlusions or hemorrhages, are detected. While it accelerates communication, specific features for managing alert fatigue (e.g., tiered alerts, customizable thresholds for notification frequency) are not explicitly detailed in the provided information.
Clinical Workflow Integration
StrokeViewer is a cloud-based, end-to-end AI solution that integrates into standard reading environments (PACS) and offers a stand-alone web-based platform. It automatically analyzes images after acquisition and sends mobile notifications to radiologists and stroke teams, allowing remote review of images on smartphones, laptops, or tablets via a web-based diagnostic viewer. The platform facilitates seamless image sharing, collaboration, and communication among stroke healthcare teams, including chat and screen sharing features, to streamline patient transfers and accelerate decision-making.
Decision Audit Trail
StrokeViewer is designed for transparency, displaying not only the final output (e.g., calculated core and penumbra volumes) but also underlying data and processing steps. This includes access to perfusion maps, Tmax thresholds, time-intensity curves, and segmentation boundaries, enabling clinicians to validate findings and interpret results in context.
Physician Tip

Leverage StrokeViewer Perfusion for rapid, quantitative assessment of ischemic core and penumbra, especially in the 6-24 hour window, to guide thrombectomy decisions. Always interpret AI results in conjunction with the full clinical picture and original imaging data, utilizing the transparent display of underlying perfusion maps and thresholds to validate findings. The mobile access and communication features are crucial for accelerating decision-making and inter-hospital collaboration in time-critical stroke care. Be aware that while notifications are instant, specific alert fatigue management features are not detailed, so integrate thoughtfully into existing alert protocols.

StrokeViewer is a cloud-based solution that integrates with PACS and offers a web-based DICOM viewer for flexible access. Its design supports seamless communication and image sharing across stroke networks, including hub-and-spoke models, facilitating rapid patient triage and transfer. The platform is also noted to partner with companies like Philips to integrate into broader stroke care pathways.

Details

Category Neurology AI, Radiology & Imaging AI
Pricing Contact for pricing — N/A
DeploymentCloud-based; can be installed as a Docker container on standard computers or virtual platforms.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

StrokeViewer Perfusion received 510(k) clearance (K231570) from the U.S. Food and Drug Administration (FDA) on December 14, 2023, for image processing and analysis of CT perfusion images of the brain to provide quantitative perfusion information in brain tissue for suspected ischemic stroke patients. This clearance expands NICo-Lab's comprehensive portfolio of FDA-cleared AI-powered imaging tools for stroke care.

Integrations
EHR Not specified
Specialties Emergency Medicine, Neurology, Radiology

What the Web Says

StrokeViewer Perfusion, developed by Nicolab, is a medical imaging software designed to aid in the diagnosis and treatment planning for stroke patients by providing rapid and automated analysis of perfusion CT scans. It aims to streamline workflows and improve decision-making in acute stroke care. Reviews highlight its speed and integration capabilities as key benefits.

Overall: Positive

Strengths

  • Rapid and automated analysis of perfusion CT scans
  • Aids in faster decision-making for stroke treatment
  • Streamlines workflow in acute stroke settings
  • User-friendly interface (reported by some users)
  • Good integration with existing PACS systems
  • Potential to improve patient outcomes through quicker intervention

Limitations

  • Cost can be a barrier for smaller institutions
  • Requires specific hardware/software compatibility
  • Learning curve for new users, though generally considered manageable
  • Reliance on accurate initial scan quality
  • Limited detailed public reviews from a wide range of sources
  • Some users desire more customization options

Based on reviews from: Nicolab Website (product information), Medical Technology Review Articles (general), Healthcare IT Forums (general discussions), Physician Forums (anecdotal mentions), G2 (limited specific reviews), Capterra (limited specific reviews)

Last updated: 2026-07-18

Ratings & Reviews

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Press & Coverage

Nicolab
Nicolab Attains Significant Milestone in Stroke Care Advancement with U.S. FDA Clearance for CT Perfusion Algorithm in StrokeViewer
Nicolab announced that its CT Perfusion algorithm, integrated into the StrokeViewer platform, received 510(k) clearance from the U.S. FDA, marking a significant step in enhancing stroke care in the US. This clearance complements prior European CE-mark and Australian TGA approvals.
2023-12
NeuroNews International
Nicolab attains US FDA 510(k) clearance for CT perfusion algorithm
Nicolab's CT perfusion algorithm, part of its StrokeViewer platform, has received 510(k) clearance from the US FDA. This regulatory achievement is expected to transform stroke management by aiding physicians in making informed clinical decisions and speeding up treatment times.
2023-12
Nicolab
Nicolab Strengthens U.S. Presence with Multiple FDA-Cleared Algorithms, Transforming Stroke Care
Nicolab announced FDA 510(k) clearance for both its StrokeViewer LVO Triaging and CT Perfusion algorithms, reinforcing its commitment to revolutionizing acute stroke care in the United States. These AI-powered tools aim to accelerate diagnosis and treatment decisions for stroke patients.
2025-11
Nicolab
Precision in Perfusion: How StrokeViewer's AI Transforms CTP into Actionable Insights
This article highlights how StrokeViewer's CT Perfusion (CTP) algorithm converts raw imaging data into actionable insights for critical stroke triage decisions. It discusses the algorithm's role in quantifying salvageable and infarcted tissue, guiding treatment decisions, and continuous innovation based on user feedback.
2025-07
NeuroNews International
Queensland Health and Nicolab partner to deliver u201cAustraliau2019s largest AI-powered stroke imaging deploymentu201d
Queensland Health has partnered with Nicolab to implement its StrokeViewer technology in 36 hospitals, marking Australia's largest AI-driven stroke imaging rollout. This initiative aims to transform stroke diagnosis and treatment, ensuring faster access to care for patients across Queensland.
2025-05
PubMed (Clinical Radiology)
Introduction and accuracy assessment of Nicolab's StrokeViewer in a developing stroke thrombectomy UK service. a service development/improvement project
This study evaluates the implementation and accuracy of StrokeViewer software for large vessel occlusion detection in a UK stroke center. It found comparable efficacy to a junior registrar, with sensitivity and specificity values close to advertised claims, despite initial technical challenges.
2025-01
Philips
Philips and Nicolab Collaborate to Advance Stroke Care in India
Philips and Nicolab are expanding their collaboration to advance stroke care in India, combining Philips' imaging expertise with Nicolab's StrokeViewer AI platform. This partnership aims to strengthen clinical workflows, support faster decision-making, and improve access to life-saving stroke treatment in a country with a high incidence of stroke.
2025-10
The Imaging Wire
Real-World Stroke AI Implementation
A study in Clinical Radiology highlights the potential of Nicolab's StrokeViewer AI software to improve stroke diagnosis, while also addressing challenges in real-world AI implementation. The study found improved performance after software tweaks and training sessions.
2024-11

Videos

Product demos, reviews, and walkthroughs for StrokeViewer Perfusion.

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Frequently Asked Questions

StrokeViewer Perfusion is a cloud-based AI solution that automatically analyzes CT perfusion and MRI scans, providing rapid quantification of ischemic core and penumbra volumes. It integrates by sending immediate notifications to stroke teams and allowing remote review of perfusion maps and AI results on various devices, facilitating faster, informed treatment decisions and inter-hospital collaboration.
StrokeViewer's CT Perfusion algorithm has received 510(k) clearance from the U.S. Food and Drug Administration (FDA). It also holds CE marking for the European Union and TGA approval in Australia, demonstrating its adherence to rigorous regulatory standards in multiple key global markets.
While a powerful tool, StrokeViewer Perfusion is not a standalone diagnostic and its output must be interpreted within the full clinical context of the patient. CTP imaging itself has limitations such as susceptibility to patient motion, potential for ghost cores or false positives, and a higher radiation dose compared to some alternatives.
StrokeViewer Perfusion provides automated analysis of CT and MR perfusion images, aiming to reduce inter-rater variability and accelerate decision-making compared to manual interpretation. While other automated software like RapidAI, Syngo.via, and Cercare Medical Neurosuite also exist, studies have shown variability in core volume estimates across different CTP software solutions.
Specific pricing details for StrokeViewer Perfusion are not publicly disclosed in the provided information. Typically, such advanced medical imaging software solutions are offered through a subscription-based model, with pricing often tailored to the hospital system's size, volume, and specific integration needs. Direct inquiry with Nicolab is usually required for detailed pricing information.
Yes, Nicolab's StrokeViewer platform offers perfusion analysis for both CT and MR images. This flexibility ensures clinicians have access to vital perfusion data regardless of their hospital's preferred imaging protocols, supporting informed decision-making for stroke diagnosis and treatment.
StrokeViewer Perfusion quantifies ischemic core and penumbra volumes, calculates mismatch ratios, and generates multicolored perfusion maps (TMax, CBF, CBV). This data helps clinicians assess brain tissue viability and identify patients, particularly in the late window (6-24 hours), who may benefit from thrombectomy based on criteria like those from the DEFUSE 3 trials.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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