Products

ElucidVivo A.3
Elucid
Cardiology AI
ElucidVivo A.3 by Elucid Bioimaging is an FDA-cleared AI-powered medical image analysis system that provides quantitative analysis of arterial plaque composition and stability from CT angiography. It assists physicians in atherosclerosis patient stratification and optimizes treatment decisions by offering detailed visualization and measurement of plaque characteristics validated against histology.

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About Elucid Bioimaging

Elucid Bioimaging is a pioneering medical technology company that leverages artificial intelligence (AI) and quantitative analysis to provide physicians with advanced imaging analysis software for cardiovascular disease. Their core mission is to predict and personalize the prevention of heart attacks and strokes by offering a more precise view of atherosclerosis, the root cause of cardiovascular disease. The company’s flagship product, Plaque-IQ™, is an FDA-cleared computed tomography angiography (CTA) algorithm that objectively quantifies and characterizes plaque morphology, validated against ground-truth histology—the gold standard for plaque characterization.

Elucid’s platform transforms standard CT images into a dynamic, interactive map of disease, enabling clinicians to assess plaque composition, coronary blockages, and ischemia risk. This technology aims to move cardiovascular care from population-based treatment towards personalized diagnosis and treatment decisions. In addition to Plaque-IQ™, Elucid also offers FFR-IQ™ software, which provides noninvasive assessment of coronary physiology (FFR-CT) derived from their plaque analysis, integrating anatomy, plaque biology, and physiology to help identify coronary blockages and the extent of ischemia. The company’s solutions are designed to support health systems, cardiologists, radiologists, and vascular specialists, with a focus on improving patient outcomes and reducing costs.

Focus Areas

AI-powered cardiovascular imaging software quantitative plaque analysis fractional flow reserve (FFR-CT) atherosclerosis precision medicine medical imaging & diagnostics healthtech

Business Intelligence

TechnologyCloud-native, AI operating system, machine learning, patented computer algorithms based on histological data, DICOM-wrapped PDFs, interactive browser-based reports

What Physicians Need to Know

AI-Powered Cardiovascular Imaging Software
Elucid Bioimaging develops AI-powered software for analyzing cardiovascular CT angiography (CCTA) scans. Their platforms, Plaque-IQ and FFR-IQ, provide a precise view of atherosclerosis, the root cause of cardiovascular disease, to help physicians personalize care.
Quantitative Plaque Analysis
Elucid's Plaque-IQ software is FDA-cleared and CE-marked for non-invasive quantification and classification of atherosclerotic plaque morphology in both coronary and carotid arteries. It is unique in its validation against ground-truth histology, the gold standard for plaque characterization, allowing for the identification and quantification of high-risk plaque features like Lipid Rich Necrotic Core (LRNC).
Fractional Flow Reserve (FFR-CT)
Elucid's FFR-IQ software, recently FDA-cleared, provides a non-invasive estimation of fractional flow reserve from coronary CT angiography (FFR-CT). This 'BioIntegrated FFR-CT' approach incorporates coronary anatomy and plaque composition into its estimation of coronary physiology, aiming for greater accuracy than traditional methods.
Atherosclerosis and Precision Medicine
Elucid's technology focuses on providing a more precise view of atherosclerosis, enabling physicians to move beyond population-based risk assessment towards personalized treatment decisions. By analyzing plaque biology and physiology, their software helps in early detection and prevention of cardiovascular disease.
Medical Imaging & Diagnostics
Elucid's platforms transform CT images into dynamic, interactive maps of disease, offering detailed insights into plaque composition and vessel structure. This supports clinicians and researchers with precise, non-invasive diagnostic information for heart and vascular health.
Healthtech
As a Boston-based medical technology company founded in 2013, Elucid Bioimaging leverages AI and machine learning to advance cardiovascular care. They have secured significant funding, including a $55 million Series D round in September 2026, to expand their commercial platforms and research.
Physician Tip

Elucid's technology offers physicians a comprehensive platform for personalized cardiovascular care. The Plaque-IQ software provides histology-validated quantitative plaque analysis, including the identification of high-risk Lipid Rich Necrotic Core (LRNC), which is crucial for assessing heart attack and stroke risk. The FFR-IQ software offers a BioIntegrated FFR-CT that considers both anatomy and plaque composition for more accurate physiological assessment of coronary blockages. This integrated approach allows for lesion-specific assessment and supports more informed treatment decisions, potentially reducing unnecessary invasive procedures. The ability to analyze both coronary and carotid arteries from a single CCTA scan provides a holistic view of systemic atherosclerotic risk. Furthermore, Elucid's technology is designed to be transparent and reproducible, offering detailed insights beyond traditional stenosis assessment. The recent Category I CPT code for quantitative coronary plaque analysis (75577) and expanding reimbursement coverage also make this technology more accessible.

Elucid's software works with all CTA scanners using standard acquisition protocols. The platform supports DICOM integration and PACS/EMR interoperability for seamless integration into clinical workflows. While Elucid does not publish a public developer program, API reference, or SDK, their product is delivered as an end-user clinical platform.

Products by Elucid Bioimaging

1 product in the directory

ElucidVivo A.3
Elucid
Cardiology AI
ElucidVivo A.3 by Elucid Bioimaging is an FDA-cleared AI-powered medical image analysis system that provides quantitative analysis of arterial plaque composition and stability from CT angiography. It assists physicians in atherosclerosis patient stratification and optimizes treatment decisions by offering detailed visualization and measurement of plaque characteristics validated against histology.

What the Web Says

Elucid Bioimaging offers an AI-powered SaaS platform, PlaqueIQ, for cardiovascular disease assessment, which analyzes coronary CT angiography to quantify plaque and identify high-risk features. The company has received FDA clearance for PlaqueIQ and recently for its FFR-IQ software, and has secured significant funding. Employee reviews indicate mixed sentiments regarding management and culture, with some concerns about ageism, while product reviews highlight its histology-validated approach and utility for clinicians.

Overall: Mixed

Strengths

  • PlaqueIQ is FDA-cleared and histology-validated, providing accurate plaque analysis.
  • The PlaqueIQ tool helps clinicians assess cardiovascular disease, quantify plaque, and identify high-risk features.
  • Plaque analysis using Elucid's software is reimbursable with a dedicated CPT code.
  • The company's FFR-IQ software provides a noninvasive estimate of fractional flow reserve, enhancing diagnostic capabilities.
  • Elucid's technology allows for detailed, lesion-level plaque inspection, aiding in personalized treatment.
  • Good work-life balance and job security reported by some employees.

Limitations

  • Some employee reviews mention issues with management and company culture.
  • Concerns about ageism have been raised by former employees.
  • The product workflow involves trained human analysts, meaning results are not instant.
  • No published studies directly evaluate PlaqueIQ, with trade coverage primarily from the vendor.
  • Lack of EHR or PACS integration, and no HIPAA, SOC 2, or HITRUST attestation listed.
  • Competitors like HeartFlow and Cleerly offer similar plaque analysis tools, with no head-to-head data on accuracy or turnaround.

Based on reviews from: jobtoday.com, indeed.com, simplyhired.com, simplify.jobs, medaiverdict.com, elucid.com, massdevice.com, medtechdive.com, yespress.io, slashdot.org, elion.health

Last updated: 2026-10-26

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Press & Coverage

Business Wire
Elucid Raises $55 Million in Oversubscribed Series D Financing
Elucid announced it raised $55 million in an oversubscribed Series D financing round, bringing its total funding to approximately $185 million. The funding will accelerate the commercial expansion of its AI-powered cardiovascular imaging platform and support strategic partnerships.
2026-09
Elucid Bioimaging
Elucid Announces FDA Clearance of FFR-IQ™ and Commercial Availability of the Most Accurate¹ FFR-CT Software
Elucid announced it received U.S. FDA 510(k) clearance for FFR-IQ™, its software for noninvasive estimation of fractional flow reserve from CT scans. This software aims to provide accurate assessment of coronary physiology.
2026-10
Elucid Bioimaging
Elucid Statement on Heartflow Lawsuit: Reaffirms Mission, Confidence in Its Technology, and Commitment to Patients and Physicians
Elucid Bioimaging reaffirmed its commitment to its mission and expressed confidence in its technology and intellectual property following a lawsuit filed by Heartflow, Inc. The company stated it would defend against the claims through appropriate legal channels.
2026-10
Elucid Bioimaging
Elucid Appoints Mark Miller as Chief Revenue Officer to Lead Commercial Expansion Ahead of BioIntegrated FFR-CT Launch
Elucid announced the appointment of Mark Miller as Chief Revenue Officer. Miller will lead the company's commercial expansion efforts as it prepares for the launch of its BioIntegrated FFR-CT product.
2026-09
MedTech Dive
Elucid wins FDA 510(k) nod for heart plaque image analysis software
Elucid received 510(k) clearance from the FDA for its PlaqueIQ software, designed to analyze coronary CT angiography images and create 3D models to quantify and classify plaque morphology. This aims to improve predictions of heart attack and stroke risk.
2024-10
Current Problems in Cardiology
Intra- and inter-reader reproducibility in quantitative coronary plaque analysis on coronary computed tomography angiography.
This peer-reviewed study evaluates the reproducibility of quantitative coronary plaque analysis using coronary computed tomography angiography, a method relevant to Elucid Bioimaging's technology. The study assesses both intra-reader and inter-reader variability in plaque measurements.
2024
Elucid Bioimaging
Elucid Raises $80 Million in Series C Round Led by Elevage Medical Technologies
Elucid announced an $80 million Series C funding round led by Elevage Medical Technologies, with participation from other investors. This funding is intended to expand commercialization efforts for its AI-powered imaging analysis software for cardiovascular disease.
2023-11
Elucid Bioimaging
CMS Final Rule Doubles Reimbursement for Cardiac CT Angiography (CCTA), Expanding Access to Critical Cardiovascular Imaging
Elucid Bioimaging announced that a final rule from CMS will significantly increase reimbursement for cardiac CT angiography (CCTA) starting January 1, 2025. This change is expected to make the technology more accessible to hospitals and patients.
2024-11

Frequently Asked Questions

Elucid Bioimaging's AI-powered software, primarily Plaque-IQ, addresses the need for precise, non-invasive quantification and characterization of atherosclerotic plaque in coronary and carotid arteries. It aims to move beyond traditional, subjective assessments to provide objective, histology-validated insights into plaque morphology, including high-risk features like lipid-rich necrotic core, to better predict and prevent heart attacks and strokes.
Plaque-IQ contributes to precision medicine by providing detailed, patient-specific information about plaque composition and morphology, validated against ground-truth histology. This allows physicians to prioritize and personalize treatment strategies based on the actual disease characteristics rather than population-based risk estimates, enabling more targeted interventions and personalized care pathways.
Elucid Bioimaging's FFR-IQ (formerly FFR-CT) is an AI-powered software that provides a non-invasive estimate of fractional flow reserve (FFR) from coronary CT angiography. It recently received FDA 510(k) clearance and is designed to help physicians identify coronary blockages and the extent of a patient's ischemia, integrating anatomy, plaque biology, and physiology for a comprehensive assessment.
Elucid's Plaque-IQ coronary plaque analysis received a new Category I CPT code (75577) effective January 1, 2026, with a national average payment of $1,012 for imaging centers and physician offices, and $951 for hospital outpatient settings. Widespread coverage from public and private payers, including Medicare, Aetna, Humana, Cigna, and UnitedHealthcare, is in place, covering over 70% of insured Americans.
Elucid Bioimaging aims to expand strategic partnerships with leading medical technology companies and offers support for its clinical platforms. While specific details on direct provider support programs are not extensively detailed, the company's focus is on enabling efficient clinical insights and providing a comprehensive clinical decision platform.
Elucid Bioimaging appears to be a stable and growing company, having raised approximately $185 million in total funding to date. This includes a recent oversubscribed $55 million Series D financing round in September 2026, with participation from new and existing investors, including a large unnamed medtech company.
Elucid Bioimaging's Plaque-IQ software is FDA-cleared and CE-marked, and it is the only FDA-cleared CT plaque platform trained and validated on histology for quantifying plaque morphology, including lipid-rich necrotic core. Their FFR-IQ software also recently received FDA 510(k) clearance.

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