Workflow Box

by Mirada Medical  · Based in United Kingdom → — Software to accelerate cancer care through AI-powered automation.
Nuclear Medicine Oncology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

Mirada Medical’s Workflow Box is an advanced AI-automation platform designed to significantly enhance the efficiency and precision of cancer treatment planning, particularly within radiation oncology. Leveraging deep learning and multi-atlas contouring technologies, it automates the laborious task of delineating tumors and organs-at-risk (OARs) on various medical images, including CT, MR, and PET scans. The platform aims to reduce manual effort, save time, and improve the consistency and accuracy of contouring, which is critical for minimizing damage to healthy tissue during radiation therapy. Workflow Box also features robust data routing enhancements, ensuring flexible and seamless integration into existing radiotherapy workflows. It supports a ‘Zero-Click’ automation approach, allowing clinicians to focus on complex cases while the system handles routine tasks, thereby accelerating the treatment pathway for patients.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI-based autocontouring (Deep Learning Contouring - DLCExpertu2122)
  • Zero-Clicku2122 automation platform
  • Multi-atlas contouring
  • Deformable image registration for re-contouring
  • Intelligent data routing and integration
  • Support for multiple modalities (CT, MR, PET, RTSTRUCT)
  • Organ At Risk (OAR) contouring
  • Tumor and target volume delineation
  • Vendor-agnostic integration
  • Workflow prioritization for critical cases

Use Cases

  • Accelerating cancer treatment planning
  • Automating OAR and target volume contouring in radiation oncology
  • Improving consistency and accuracy in contouring
  • Streamlining diagnostic imaging workflows
  • Adaptive radiotherapy planning
  • Reducing manual effort in image processing tasks

What Physicians Need to Know

Key Capabilities
AI-powered autocontouring for Organs at Risk (OARs) and target volumes in radiation treatment planning, utilizing deformable image registration and machine learning. Features workflow prioritization, data routing for DICOM-compliant data, and supports multiple modalities (CT, MR, PET, SPECT, RTSTRUCT). Includes an AI Library for structures in head and neck, thorax, breast, and prostate.
Clinical Utility
Accelerates cancer treatment planning by significantly reducing contouring time (up to 75% time savings with DLCExpert component). Enhances consistency and accuracy of OAR contouring, minimizing damage to healthy tissue. Improves efficiency to manage increasing cancer cases and backlogs, supporting confident diagnosis, treatment response assessment, and planning of radiation therapy or surgical interventions.
Integration Options
Seamlessly integrates with PACS and can load images from any scanner. Supports DICOM data routing within hospital networks and is compatible with Microsoft Windows server environments. Deployable as a standalone workstation or thin client for remote reporting. Offers support for custom application integration and works with various treatment planning systems.
Compliance Status
Mirada Medical was the first to achieve regulatory clearance for clinical AI autocontouring in radiation treatment planning. Workflow Box 2.0, including DLCExpert, has FDA 510(k) clearance and CE marking for the European market. Verification and Validation comply with CFR 21 Part 820 and DICOM standards. It is intended for use by trained medical professionals and not for automatic lesion detection.
Pricing Model
Mirada Medical offers flexible and highly configurable software with various licensing and deployment options. Pricing is typically customized based on specific requirements, suggesting an enterprise or custom quote model.
User Experience
Designed as a 'Zero-Clicku2122 automation platform' to simplify complex image processing tasks and enhance efficiency. Once data is routed, auto-contouring requires no user interaction, with configuration managed via an administration interface. Generated contours are often described as 'indistinguishable from human drawn contours,' though review and editing with appropriate visualization software are required.
Support Quality
Mirada Medical emphasizes continuous innovation and improvement, with products supported by a dedicated team of customer support specialists. Online help guides and physical instructions are available upon request.
Implementation Complexity
Involves configuring data routing rules and workflows via an administration interface. While integration with existing PACS and scanners is designed to be seamless, creating a robust contouring atlas can be a thorough and time-consuming process. User-performed installation and configuration may be at the user's risk unless otherwise agreed.
Evidence Base
Backed by Mirada Medical's scientific insight and global in-clinic experience, with regulatory clearances for AI autocontouring. Studies demonstrate significant time savings and improved consistency. Clinical validation has been performed for various anatomical sites, though some studies indicate that further validation is needed for small or highly variable structures, and manual review remains crucial.
Physician Tip

Leverage Workflow Box for its significant time-saving potential in OAR and target volume contouring, particularly in high-volume radiation oncology settings. Always critically review the automatically generated contours using appropriate visualization software, as the tool is an aid and not a replacement for clinical judgment. While highly effective for many structures, be aware that small or highly variable anatomical regions may require more manual adjustment and further clinical validation. Utilize the workflow prioritization features to manage critical cases efficiently.

Workflow Box is designed for seamless integration into existing clinical environments. It is DICOM-compliant, allowing easy data exchange with PACS, scanners, and various treatment planning systems. The platform's flexibility also supports the integration of custom applications, enabling tailored solutions within your hospital network.

Details

Category Oncology AI, Radiology & Imaging AI
Pricing Contact for pricing — Pricing information is not publicly available; contact Mirada Medical for a quote.
DeploymentServer-based application supporting Microsoft Windows 10 (64-bit) and Microsoft Windows Server 2016. Can be deployed as standalone workstation or thin client solution.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

FDA 510(k) clearance K181572 was granted on July 10, 2018, for Workflow Box. It is classified as a Class II Picture Archiving and Communications System (PACS) component, intended for routing image data and structures to automatic image processing workflows, including atlas-based, image registration-based re-contouring, and machine learning-based contouring.

Integrations
EHR Not specified
Specialties Nuclear Medicine, Oncology, Radiology

What the Web Says

Mirada Medical's Workflow Box is an automated contouring software primarily used in radiation therapy planning to delineate target volumes and organs at risk (OARs). It aims to save time for radiation oncologists and improve consistency in contouring. While it significantly reduces the time spent on initial delineation, physicians' review and corrections are still necessary, especially for smaller or more complex structures.

Overall: Mixed

Strengths

  • Significant time-saving in delineation of target volumes and OARs, potentially reducing contouring time by about 40%.
  • Improves consistency and reproducibility in delineation practices.
  • Can contour a large number of structures (over 160) on CT and MRI images across various body regions.
  • Supports routing of data to and from DICOM nodes within a hospital network, enabling automated workflows.
  • Considered one of the first commercially available AI auto-contouring solutions.
  • Produces acceptable quality work for many structures, with a high percentage of auto-delineations scored as clinically acceptable with or without corrections.

Limitations

  • Remains insufficiently accurate for some lymph node volumes (e.g., IMN) and small structures in OAR delineation, requiring manual correction.
  • Requires further clinical validation before widespread use in daily practice.
  • Does not have a built-in editor or confirmed CBCT/PET support.
  • Lacks a user interface for visualizing image data, requiring external software for review and editing.
  • Not intended to automatically detect lesions.
  • Evidence primarily consists of small, single-institutional studies, with a lack of transparency regarding development and algorithms.

Based on reviews from: PMC, RT Medical Systems, Artificial intelligence auto-contouring to aid radiotherapy treatment planning [GID-HTE10015] External Assessment Group report N - NICE, Enhancing Radiotherapy Workflow for Head and Neck Cancer with Artificial Intelligence: A Systematic Review - MDPI, accessdata.fda.gov, University of Groningen, ResearchGate, Apposite Capital, Innolitics, AAPM, Maastricht University, AIR Unimi

Last updated: 2026-07-18

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Press & Coverage

MDPI (International Journal of Medical Sciences)
Enhancing Radiotherapy Workflow for Head and Neck Cancer with Artificial Intelligence: A Systematic Review
This systematic review from June 2023 discusses the use of AI in radiotherapy for Head and Neck Cancer, highlighting how a commercially available deep learning contouring (DLC) tool like Mirada Medical's Workflow Box 2.0, DLCExpert, is used for automating OAR segmentation.
2023-06
British Journal of Radiology
Clinical evaluation of atlas-based auto-segmentation in breast and nodal radiotherapy
This article from September 2023 details a study optimizing delineation procedures for breast cancer patients using Mirada Medical's Workflow Box software for automatic contouring. It notes that while the software saves time, further clinical validation is needed for certain small structures.
2023-09
Mirada Medical
University Medical Center Groningen (UMCG) deploys DLCExpert
A May 2023 news release from Mirada Medical announces that UMCG has integrated Workflow Box clinically to deliver autocontoured plans using both Atlas and DLCExpert, addressing concerns about contouring consistency across their large radiation oncology department.
2023-05
NICE
Artificial intelligence (AI) technologies to aid contouring for radiotherapy treatment planning: early value assessment
A September 2023 report from NICE assesses AI technologies for radiotherapy contouring, including Mirada Medical's DLCExpert, deployed on the Workflow Box platform, noting its ability to contour over 160 structures and improve workflow efficiency and consistency.
2023-09
RT Medical Systems
Best AI Auto-Contouring Software for Radiotherapy 2026
This June 2026 article reviews AI auto-contouring software for radiotherapy, highlighting Mirada DLCExpert delivered through Mirada's Workflow Box as a 'zero-click' appliance for high-volume automated OAR contouring in multi-TPS environments.
2026-06
Mirada Medical
Mirada Medical heralds 'step change' in the use of artificial intelligence in cancer treatment planning
An August 2021 press release from Mirada Medical discusses Workflow Box 2.6 platform updates, which aim to deliver enhanced AI-based cancer treatment planning support for clinicians.
2021-08
Mirada Medical
Mirada Medical showcases DLCExpertu2122, the first FDA-cleared Artificial Intelligence (AI) software for Contouring in Radiation Oncology, at ASTRO 2018
This October 2018 press release announces Mirada Medical showcasing DLCExpert at ASTRO 2018, noting its FDA 510(k) clearance as part of Workflow Boxu2122 2.0, Mirada's Zero-Clicku2122 automation platform, and its role as the world's first AI-powered autocontouring solution.
2018-10
AuntMinnie
FDA clears Mirada's radiation oncology AI software
A July 2018 article reports on the FDA clearance of Mirada's DLCExpert AI software for radiation oncology, which was cleared as part of Mirada's Workflow Box and is reported to reduce contouring time by 75%.
2018-07

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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