Neosoma Brain Mets

Neurosurgery Oncology Radiology

Overview

Neosoma Brain Mets is an FDA-cleared AI-powered software medical device designed for the rapid MRI assessment and accurate, consistent analysis of brain metastases. It provides novel tumor insights to physicians and researchers in near-real-time, supporting radiology, radiation oncology, medical oncology, and surgical workflows, as well as tumor board decision-making. The technology identifies lesions as small as 1mm3 isotropic and can track any number of identified lesions over time. It operates on routinely-acquired T1 post-contrast sequences, requiring no special acquisition protocols. Neosoma Brain Mets auto-contours target (GTV) volumes and integrates seamlessly into radiation oncology and surgical planning software such as Eclipse, MIM, Brainlab, Gamma Plan, and Stealth. The platform is cloud-based, web-based, PACS-integrated, and offers an intuitive interface with interactive charts, 3D/2D visualizations, and smart segmentation/contour editing tools to expedite clinical case review. It is intended for use by qualified and trained medical professionals for informational purposes and not to replace manual contouring or detect tumors for diagnosis.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Rapid MRI assessment and analysis
  • Accurate and consistent lesion identification (as small as 1mm3 isotropic)
  • Near-real-time study processing
  • Longitudinal tracking of brain lesions over time
  • Operates on routinely-acquired T1 post-contrast sequences
  • Automated Gross Tumor Volume (GTV) contouring
  • Interoperability with radiation treatment and surgical planning software (e.g., Eclipse, MIM, Brainlab, Gamma Plan, Stealth)
  • Cloud-based, web-based, and PACS-integrated platform
  • Interactive charts, 3D/2D visualizations, and smart segmentation/contour editing tools
  • MRI protocol tolerant (no changes to acquisition protocols needed)
  • Reimbursable (Available Category 3 CPT Codes: 0865T, 0866T)

Use Cases

  • Assessment of brain metastases
  • Longitudinal tracking of brain lesions
  • Radiation treatment planning (GTV contouring)
  • Surgical planning
  • Tumor board decision-making
  • Clinical research and trials

What Physicians Need to Know

Brain MRI/CT Analysis
Neosoma Brain Mets is a Software as a Medical Device (SaMD) designed for the semi-automatic segmentation of previously diagnosed brain metastases on T1 post-contrast MRI sequences. It automatically identifies, segments, and tracks brain metastases on routinely acquired MRI sequences. The software provides quantitative information, including lesion-level insights and volumetric measurements of individual lesions over time. It can identify lesions as small as 1mm³ isotropic and operates on routinely-acquired T1 post-contrast sequences without requiring special acquisition protocols. The technology is intended to assist trained medical professionals in contouring known or previously diagnosed brain tumors on MRI images for informational purposes and is not meant to replace manual contouring or be used for tumor detection or diagnosis. It is intended for use in adult patients only.
Neurodegenerative Disease Screening
Neosoma Brain Mets is specifically designed for the analysis of brain metastases and does not currently offer features for neurodegenerative disease screening. Its focus is on tumor identification, segmentation, and tracking.
Triage Prioritization Speed
Neosoma Brain Mets delivers rapid MRI assessment and accurate, consistent analysis with near-real-time study processing. This expedites lesion identification, measurement, tracking, and target (GTV) contouring. The platform is built for speed, offering per-timepoint and per-patient reports and summaries, a lesion quick-review wizard, and smart editing tools.
Mobile Notification System
The provided information does not specify a mobile notification system for Neosoma Brain Mets. The platform is web-based for easy and secure access.
Physician Tip

Neosoma Brain Mets is a valuable tool for expediting the assessment and auto-contouring of metastatic brain lesions, particularly for radiation treatment planning and surgical planning. It provides detailed quantitative information on individual lesions and total tumor burden over time, which can be crucial for monitoring treatment response and making informed decisions in multidisciplinary tumor boards. Remember that the software is intended to assist and not replace the clinician's judgment or manual contouring, and medical professionals must finalize the generated contours. The technology operates on routinely-acquired T1 post-contrast MRI sequences, eliminating the need for special acquisition protocols.

Neosoma Brain Mets is fully integrated with Neosoma's proprietary cloud platform. It integrates directly into PACS workflows, supporting automated sending of DICOM studies for analysis and offering one-click deep linking from PACS to the Neosoma system. The software is interoperable with radiation treatment and surgical planning software, allowing easy import of lesion contours (GTVs) into systems such as Eclipse, MIM, Brainlab, Gamma Plan, and Stealth. Neosoma also has a distribution partnership with Microsoft's Nuance division.

Details

Category Neurology AI, Oncology AI, Radiology & Imaging AI
Pricing Unknown
Compliance
BAA AvailableUnknown
HIPAA CompliantUnknown
FDA Status Unknown
Integrations
EHR Not specified
Specialties Neurosurgery, Oncology, Radiology

What the Web Says

Neosoma Brain Mets is an AI-based software designed to assist healthcare professionals in the detection, tracking, and treatment planning of brain metastases. It has received FDA 510(k) clearance and is integrated into Neosoma's cloud platform. The software automates lesion identification, volumetric measurement, and radiation therapy contouring from standard MRI scans, aiming to expedite assessments and enhance decision-making in neuro-oncology workflows.

Overall: Positive

Strengths

  • Automates lesion identification, volumetric measurement, and radiation therapy contouring, saving time and effort for clinicians.
  • Provides rapid MRI assessment and accurate, consistent analysis with near-real-time study processing.
  • Capable of identifying, contouring, and tracking an unlimited number of individual lesions, even those as small as 1mm³ isotropic.
  • Integrates seamlessly into radiation oncology and surgical planning software.
  • Operates on routinely-acquired T1 post-contrast MRI sequences, requiring no special acquisition protocols.
  • Supports multidisciplinary team collaboration across radiology, radiation oncology, medical oncology, and surgical workflows, as well as tumor board decision-making.

Limitations

  • Not intended to replace the clinician's current standard practice of manual contouring or to detect tumors for primary diagnosis.
  • Specifically designed for adult patients (age 22 and older) and not intended for use with images representing other types of brain lesions.
  • Medical professionals must finalize (confirm or modify) the contours generated by the software.
  • Limited information available from independent tech reviewers, G2, Capterra, or extensive Reddit discussions directly about the product, with Reddit discussions primarily focusing on personal experiences with brain metastases rather than the software itself.

Based on reviews from: alcancercongress.org, fda.gov, neosomainc.com, inspire.com, beckershospitalreview.com, beckersoncology.com, diagnosticimaging.com, reddit.com, innolitics.com, businesswire.com, nih.gov

Last updated: 2026-10-31

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Press & Coverage

prweb.com
Neosoma Announces Receiving FDA 510(k) Clearance for Brain Mets
Neosoma received FDA 510(k) clearance for its Brain Mets software medical device, which integrates into Neosoma's cloud platform to provide novel tumor insights for brain metastases. This technology aims to assist multidisciplinary teams in radiology, radiation oncology, medical oncology, and surgical workflows by expediting lesion identification, measurement, tracking, and target contouring.
2025-12
innolitics.com
Neosoma Brain Mets FDA 510(k) Clearance
Neosoma Brain Mets received FDA 510(k) clearance on December 17, 2025, after a 3-month review with no major deficiencies. The product uses a Convolutional Neural Network (CNN) to automatically identify, segment, and track brain metastases on MRI sequences, integrated into PACS workflows.
2025-12
neosomainc.com
Neosoma's strategic partnership with Calyx enables faster, more precise tumor assessment in brain cancer clinical trials.
Neosoma announced a strategic partnership with Calyx, a global eClinical and regulatory solutions provider, to enhance brain cancer clinical trials. This collaboration aims to improve the accuracy and precision of tumor assessment by utilizing Neosoma's 3-D longitudinal tumor measurements, addressing variability in current manual 2-D methods.
unknown
wbjournal.com
Groton medtech firm raises $3.5M for cancer-focused AI platform
Neosoma, a Groton-based medical technology company, raised $3.52 million in venture capital towards a $5.8 million goal. The company, founded in 2019, uses AI software to provide 3D analysis of cancerous tumors, with its Neosoma Brain Mets platform gaining FDA clearance in December.
2026-04
neosomainc.com
Neosoma Participates in Big Data Federated Learning Study
Neosoma participated in a UPenn-led federated learning study involving nearly 6,500 brain cancer MRIs from 71 sites across six continents. The study investigated the benefits of federated-learning-based AI for glioblastoma segmentation.
2026-02
neosomainc.com
Neosoma GmbH and Inselspital Announce Collaboration
Neosoma GmbH and Inselspital announced an expanded collaboration to study Neosoma's high-grade glioma auto-contouring capabilities and the benefits for radiation treatment planning workflows. The collaboration will also include brain metastases and OAR, aiming to impact more patients.
2025-11
neosomainc.com
Neosoma Expands Board of Directors with Debbie Millin and Fred Driscoll
Neosoma announced the appointment of Debbie Millin and Fred Driscoll to its Board of Directors, a move intended to support the company's growth and mission to become a leader in neuro- and CNS oncology software.
2023-03
neosomainc.com
Neuro-Oncology Advances Publishes About Neosoma's Technology
Neuro-Oncology Advances, a peer-reviewed journal, published an article detailing the technology and development of Neosoma HGG (NS-HGlio). Dr. Aly Abayazeed, Neosoma's Co-Founder and Chief Medical Officer, was the primary author.
2023-01

Videos

Product demos, reviews, and walkthroughs for Neosoma Brain Mets.

View all on YouTube

Frequently Asked Questions

Neosoma Brain Mets integrates into existing workflows by providing automated identification, measurement, and contouring of brain metastases from routine MRI scans. It supports multidisciplinary teams, including radiology, radiation oncology, medical oncology, and surgical workflows, as well as tumor board decision-making. The software expedites lesion identification, measurement, tracking, and target (GTV) contouring, all within a secure, cloud-based, PACS-integrated solution.
Yes, Neosoma Brain Mets has received FDA 510(k) clearance. It is intended for use by qualified and trained medical professionals to contour (segment) known or previously diagnosed brain tumors on MRI images. The software is for informational purposes only and is not intended to replace manual contouring, alter original MRI images, or be used for tumor detection or diagnosis.
Traditional methods for assessing brain metastases involve manual identification, measurement, and contouring of lesions from MRI scans, which can be time-consuming. Neosoma Brain Mets offers an AI-powered solution that automates these processes, providing rapid MRI assessment and consistent analysis. It aims to expedite lesion identification, measurement, tracking, and target (GTV) contouring, offering a more efficient approach compared to manual methods.
Neosoma's solution is priced based on MRI volume, allowing multiple team members to have logins without additional seat licenses. There are two Category 3 CPT codes that allow departments to submit claims on a per-MRI-analysis basis, whether or not a diagnostic MRI is performed in the same session.
Neosoma Brain Mets is intended for semi-automatic segmentation of previously diagnosed brain metastases on T1 post-contrast MRI sequences in adult patients (age 22 and older). It is not intended for use with images representing other types of brain lesions. While the software provides automated contours, medical professionals must finalize (confirm or modify) these contours using external platforms. The technology is for informational purposes and does not replace the clinician's standard practice of manual contouring, nor is it for primary diagnosis or tumor detection.

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Suggest an Edit → | Report an issue | Last Verified: 2026-04-18 | First Added: 2026-04-18

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