Products

Neosoma Platform
Neosoma
Clinical Decision Support & Reference
The Neosoma Platform is a cloud-based, FDA-cleared AI tool for neuro-oncology, providing automated tumor mapping, lesion tracking, and real-time insights for brain metastases and gliomas.
NS-HGlio
Neosoma
Neurology AI
Neosoma offers an FDA-cleared AI-based software platform, NS-HGlio, for semi-automatic labeling, visualization, and volumetric quantification of high-grade brain gliomas from standard MRI images, aiding in treatment planning and longitudinal assessment.
Neosoma Brain Mets
Neosoma
Neurology AI
Neosoma Brain Mets is an FDA-cleared AI-powered software for rapid MRI assessment and auto-contouring of brain metastases, providing near-real-time insights for multidisciplinary neuro-oncology teams.

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About Neosoma

Neosoma is a healthcare AI company dedicated to advancing the treatment of brain cancers through an integrated portfolio of innovative, artificial intelligence-based software products combined with a Clinical Management Software Platform. The company’s core technology utilizes AI software to create a precise 3D analysis of cancerous tumors, providing physicians with critical insights into how a patient’s tumor is changing over time based on magnetic resonance imaging (MRI) sequences.

Neosoma’s comprehensive Software-as-a-Service (SaaS) solution is designed to assist neuro-oncology clinical teams in making better treatment decisions, with the ultimate goal of improving clinical outcomes, increasing clinical process efficiency, and reducing costs. Their cloud platform, Neosoma Brain Mets, and their initial software-based medical device, Neosoma HGG (High-Grade Glioma), have both received U.S. Food and Drug Administration (FDA) 510(k) clearance. Neosoma HGG, for instance, conducts detailed tumor segmentation, volumetric measurements, generates imaging for 3D geometric analysis, and longitudinally tracks patients with high-grade glioma brain tumors, offering objectivity to clinical decisions. The company is also developing a full suite of software technologies to become a leader in the neuro-oncology software field, with a pipeline that includes meningiomas, acoustic neuromas, pediatric indications, and OAR auto-segmentation.

Focus Areas

Neuro-oncology Brain Cancers High-Grade Gliomas Brain Metastases AI-based Image Analysis 3D Tumor Analysis Longitudinal Tumor Tracking Clinical Management Software Clinical Trials Decision Support

Business Intelligence

Key InvestorsAlliance of Angels, Filter Fund, TCA Venture Group, Octane (California), Hackensack Meridian Health
PartnershipsNuance Precision Imaging Network (Microsoft), Calyx, Hackensack Meridian Health, University of Bern / ARTORG Center, Inselspital
AcquisitionsNone known
TechnologyCloud-native, PACS-integrated, interoperable with radiation treatment and surgical planning systems, SOC2 Type II certified, HIPAA compliant, web-based, deep learning neural networks, modular platform
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Neuro-oncology Specialization
Neosoma focuses exclusively on neuro-oncology, providing AI-based solutions for brain cancers, including High-Grade Gliomas (HGG) and Brain Metastases. They have received FDA 510(k) clearance for both Neosoma HGG and Neosoma Brain Mets.
AI-based Image Analysis
Utilizes advanced AI algorithms (deep learning neural networks) for semi-automatic labeling, visualization, and precise 3D volumetric quantification of brain tumors from standard MRI images. This includes detailed tumor segmentation, measuring enhancing tissue, T2/FLAIR hyperintensity, and necrosis + cavity.
3D Tumor Analysis & Longitudinal Tracking
Offers 3D geometric analysis and robust longitudinal tracking of tumors and lesions, automatically co-registering sequences and comparing current timepoints with priors. This enables objective assessment of tumor burden, response to treatment, and changes over time, even for numerous small lesions.
Clinical Management Software
Provides a comprehensive, cloud-based platform designed for multidisciplinary neuro-oncology teams. It features an interactive web-based user interface, patient imaging database, and tools for efficient clinical workflows, including per-timepoint and per-patient reports.
Clinical Trials & Decision Support
Supports clinical trials by providing accurate, precise, and consistent 3D longitudinal tumor measurements, addressing variability inherent in manual 2D measurements. It delivers key insights in near-real-time to support clinical decisions, treatment planning, and patient counseling.
Physician Tip

Neosoma's platform offers significant advantages for neuro-oncology physicians. Leverage the AI-powered 3D volumetric analysis and longitudinal tracking for objective and precise assessment of tumor changes, which can be crucial for determining treatment response and guiding therapy adjustments. Utilize the auto-contouring feature for radiation oncology and surgical planning to save time and improve consistency. The integrated cloud platform facilitates multidisciplinary team collaboration and streamlines workflows. Remember that while the software provides highly accurate insights, it is intended to assist and not replace the clinician's final judgment or manual contouring in external systems for definitive treatment planning. The ability to track an unlimited number of brain metastases and quantify various tumor compartments (enhancing tissue, T2/FLAIR, necrosis) provides a level of detail previously challenging to obtain manually, enhancing decision-making for complex cases.

Neosoma's platform is designed for seamless integration into existing clinical environments. It is PACS-integrated, supporting automated sending of DICOM studies for analysis and offering deep linking capabilities. The technology is interoperable with various radiation treatment and surgical planning systems, including Eclipse, MIM, Gamma Plan, Stealth, and Brainlab, allowing for easy import of auto-generated GTV contours. Neosoma also partners with the Nuance Precision Imaging Network and Calyx for enhanced data sharing and clinical trial support. The cloud-based nature ensures secure, HIPAA-compliant, and SOC2 Type II certified access.

Products by Neosoma

3 products in the directory

Neosoma Platform
Neosoma
Clinical Decision Support & Reference
The Neosoma Platform is a cloud-based, FDA-cleared AI tool for neuro-oncology, providing automated tumor mapping, lesion tracking, and real-time insights for brain metastases and gliomas.
NS-HGlio
Neosoma
Neurology AI
Neosoma offers an FDA-cleared AI-based software platform, NS-HGlio, for semi-automatic labeling, visualization, and volumetric quantification of high-grade brain gliomas from standard MRI images, aiding in treatment planning and longitudinal assessment.
Neosoma Brain Mets
Neosoma
Neurology AI
Neosoma Brain Mets is an FDA-cleared AI-powered software for rapid MRI assessment and auto-contouring of brain metastases, providing near-real-time insights for multidisciplinary neuro-oncology teams.

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Press & Coverage

Worcester Business Journal
Groton medtech firm raises $3.5M for cancer-focused AI platform
Neosoma, a Groton-based medical technology company, raised $3.52 million in venture capital in April 2026, contributing to its goal of $5.8 million. The company, founded in 2019, uses AI software for 3D analysis of cancerous tumors to provide physicians with information on tumor changes.
2026-04
PRWeb
Neosoma Announces Receiving FDA 510(k) Clearance for Brain Mets
Neosoma received FDA 510(k) clearance for its Brain Mets software medical device in December 2025, marking a new era in assessing brain metastases. This AI-based software integrates into Neosoma's cloud platform, offering novel tumor insights to physicians and researchers in near real-time.
2025-12
Neosoma News Feed
Neosoma GmbH and Inselspital Announce Collaboration
In November 2025, Neosoma GmbH and Inselspital formalized and expanded their collaboration to advance oncology through AI-driven imaging analysis. The Insel Department of Radiation Oncology is deploying Neosoma's software for glioma, brain metastases, and organs at risk (OAR) auto-contouring, measurement, and longitudinal lesion tracking to support clinical research.
2025-11
Neosoma Publications
AI-Powered Analysis Reveals New Predictors of Brain Cancer Survival
A study published in CNS Oncology in December 2024, led by Dr. Benjamin M. Ellingson at UCLA, demonstrated how Neosoma's NSHGlio AI technology can predict survival in recurrent glioblastoma patients. The research utilized AI-powered volumetric analysis and radio-pathomic mapping to track tumor changes and cellular characteristics over time.
2024-12
PR Newswire
Hackensack Meridian Health Partners with Neosoma for Innovation in Brain Tumor Treatment, Research
Hackensack Meridian Health and Neosoma announced a strategic partnership in February 2023 to advance brain cancer treatment using AI. The collaboration involves clinical data sharing, research, and investment to support Neosoma's innovative imaging, tracking, and data collection methods for various brain tumors.
2023-02
Neosoma News Feed
Neuro-Oncology Advances Publishes About Neosoma's Technology
Neosoma announced in January 2023 that its technology and development for Neosoma HGG (NS-HGlio) were published in Neuro-Oncology Advances, a peer-reviewed journal. Dr. Aly Abayazeed, Neosoma's Co-Founder and Chief Medical Officer, was the primary author, highlighting the company's commitment to quality research.
2023-01
Business Wire
Neosoma Announces FDA 510(k) Clearance for Neosoma HGG
Neosoma received U.S. FDA 510(k) clearance for its first AI-based neuro-oncology software device, Neosoma HGG (High-Grade Glioma), in September 2022. This software provides precise and accurate brain tumor analysis on MRIs, offering critical insights for physicians treating challenging malignant primary brain cancers.
2022-09
Neosoma News Feed
AI-Powered Neuro-Oncology Clinical Trials
Neosoma announced a strategic partnership with Calyx, a global eClinical and regulatory solutions provider, to enable faster and more precise tumor assessment in brain cancer clinical trials. This collaboration addresses the variability in traditional 2-D tumor measurements by providing accurate, consistent 3-D longitudinal tumor measurements.
2022-11

Frequently Asked Questions

Neosoma's AI-based software, including Neosoma HGG and Neosoma Brain Mets, supports the analysis of high-grade gliomas (WHO grade 3 astrocytoma, WHO grade 4 astrocytoma, and glioblastoma) and brain metastases. Its core functionalities include automated 3D tumor segmentation, volumetric measurements, longitudinal tracking of lesions, and generating imaging for 3D geometric analysis to provide critical insights for clinical decision-making.
Neosoma's cloud platform is PACS-integrated, allowing for automated sending of DICOM studies for analysis and one-click deep linking from PACS to the Neosoma system. The platform is SOC2 Type II certified and HIPAA compliant, designed with best-in-class security practices to ensure data privacy and secure access for multidisciplinary neuro-oncology teams.
Neosoma's solution is priced based on MRI volume, allowing all multidisciplinary team members to have logins without concerns about incremental seat licenses. The platform also supports reimbursement pathways through available Category 3 CPT Codes (0865T, 0866T) for each MRI timepoint analysis.
Neosoma has strategic partnerships with Calyx to enable faster, more precise tumor assessment in brain cancer clinical trials. They also collaborate with Hackensack Meridian Health for innovation in brain tumor treatment and research, and connect to the Nuance Precision Imaging Network to broaden access to their AI solutions.
Neosoma has received U.S. Food and Drug Administration (FDA) 510(k) clearance for both its Neosoma HGG software, for high-grade glioma segmentation, and its Neosoma Brain Mets product, for the detection, tracking, and treatment planning of brain metastases. These clearances allow Neosoma to market its AI-based neuro-oncology software devices in the U.S.
Neosoma's technology provides accurate, precise, and consistent 3D longitudinal tumor measurements, which are crucial for monitoring treatment response and informing clinical decisions. The platform offers interactive charts and reports to analyze longitudinal lesion data, aiding physicians in planning procedures, assessing post-procedural results, and guiding therapies.
Founded in 2019, Neosoma is a venture capital-backed company that has raised a total of $10.2 million over five funding rounds. A recent seed round in March 2026 secured $3.52 million, indicating ongoing investment and growth in the company.

Investors

Who's funded Neosoma.

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