David Krane

David Krane is CEO of GV (formerly Google Ventures) and angel-invests from San Francisco at $250k+ checks at seed and Series A, with a healthcare focus on AI/ML in healthcare and health IT software. His positioning as the head of GV makes a personal angel check effectively a high-conviction signal, and his early Google operating background gives him strong instincts on AI-native software companies. Founders building AI-first healthcare software, infrastructure for clinical and administrative workflows, or platforms that benefit from Google-ecosystem relationships are the natural fit. The check size is meaningful enough to be a credible signal in any round, and the GV affiliation often opens doors to follow-on capital and strategic relationships across Alphabet. He is not the right audience for biotech, devices, or healthcare companies without a strong software and data spine. As with most senior platform GPs, cold outreach has near-zero yield; founders should invest in warm introductions through GV portfolio CEOs, the broader Google alumni network, or top-tier seed funds that frequently co-invest with GV. LinkedIn is the right channel only if there’s a credible mutual connection. Diligence will be rigorous and metrics-fluent, so come with a clear product, traction story, and articulated AI defensibility rather than a thesis-only narrative.