Mayo Clinic Ventures

Corporate VC Rochester, United States · Founded 1985

Mayo Clinic Ventures serves as the technology commercialization and venture investing arm of Mayo Clinic, focusing on translating clinical discoveries and healthcare innovations into market-ready products that improve patient care globally.

About Mayo Clinic Ventures

Mayo Clinic Ventures is the commercialization and venture arm of Mayo Clinic, investing in companies that align with the institution’s clinical and research priorities, including therapeutics, devices, diagnostics, and digital health. Stage focus typically runs from seed through later venture rounds, with checks in the $1M to $10M range depending on the vehicle, and the unique strategic value of Mayo’s clinical, scientific, and brand network. Healthcare exposure is exclusive, anchored in companies that emerge from Mayo IP, partner with Mayo on clinical validation, or whose products align with Mayo specialty domains in cardiology, oncology, neurology, and surgical innovation. Physician founders building science- or device-heavy companies with credible clinical pathways, particularly those with Mayo collaborations, are the cleanest fit. Founders building consumer wellness or pure software without clinical validation needs should pitch elsewhere. Geographic posture is US-led with global deal capacity. The realistic entry path is engagement through Mayo Clinic’s technology transfer and business development teams, or via a clinician collaborator at the institution; cold outreach without any Mayo connection is unlikely to advance. Founders should arrive with a defined clinical use case, defensible IP, and an articulated path to either a Mayo collaboration or a clear technical partnership. Treat Mayo Clinic Ventures as a strategic clinical partner offering brand validation and access to one of the most respected clinical institutions in the world, more than a financially driven lead.

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Healthcare AI tools backed by Mayo Clinic Ventures

Tools made by companies in Mayo Clinic Ventures's portfolio that we cover in the directory.

Corvair
AliveCor
Cardiology AI
Corvair by AliveCor is an FDA-cleared AI ECG analysis system that assists healthcare professionals in interpreting resting diagnostic ECGs with 35 cardiac determinations.
AliveCor QT Service
AliveCor
Cardiology AI
A cloud-based Software as a Medical Device (SaMD) that provides instant, accurate QT and QTc interval measurements from AliveCor 6-Lead ECGs, enabling healthcare professionals to assess cardiac safety and inform medication prescribing decisions.
Impala
AliveCor
Cardiology AI
AliveCor's 'Impala' (FDA K232035) is a portable, AI-powered 12-Lead ECG device for healthcare professionals, not a physician directory tool. AliveCor specializes in cardiac monitoring solutions.
KardiaAI
AliveCor
Cardiology AI
KardiaAI by AliveCor is an FDA-cleared AI software library for analyzing ambulatory ECG rhythms, detecting various cardiac conditions like AFib, bradycardia, and tachycardia.
Luma Health
Luma Health
Patient Engagement & Education
Luma Health is an operational AI platform for healthcare, optimizing patient engagement, access, intake, and payments. It helps healthcare organizations reduce no-shows, automate workflows, and improve patient outcomes through conversational AI, two-way messaging, and deep EHR integrations.
KardiaPro
AliveCor
Cardiology AI
KardiaPro is a comprehensive web-based portal for remote monitoring of patient ECG, blood pressure, and weight data, with FDA-cleared AI for arrhythmia detection and other cardiac determinations. It provides a secure platform to manage and review data between appointments, making it easy for healthcare professionals to analyze trends and make informed clinical decisions for improved patient care.
Kardia 12L and KAI 12L
AliveCor
Cardiology AI
Kardia 12L and KAI 12L offer a portable, AI-powered 12-lead ECG system for healthcare professionals, enabling rapid and accurate detection of numerous cardiac conditions with a simplified setup.
Cologuard / Cologuard Plus
Exact Sciences
Gastroenterology AI
Cologuard and Cologuard Plus are FDA-approved, non-invasive stool DNA colorectal cancer screening tests from Exact Sciences for average-risk individuals aged 45 and older. Cologuard Plus offers enhanced accuracy and fewer false positives. These at-home tests detect DNA markers and blood in stool to identify early-stage colorectal cancer.

Portfolio companies in our directory

Other portfolio companies

Companies in Mayo Clinic Ventures's portfolio not currently in our directory.

Team

James A. Rogers III
Chair, Department of Business Development
Andrew Danielsen
Chair, Mayo Clinic Ventures
Leif Nelson
Vice Chair, Mayo Clinic Ventures
Dr. Clark Otley
Medical Director, Department of Business Development

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Last updated 2026-05-06. Sourced from this fund's published materials.
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