syngo.CT CaScoring

by Siemens Medical Solutions USA  · Based in United States → — AI-powered quantification and visualization of coronary calcifications
Cardiology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

syngo.CT CaScoring is an advanced image analysis software package developed by Siemens Medical Solutions USA, designed to support physicians in the evaluation and documentation of calcified coronary lesions from Computed Tomography (CT) data sets. This software allows for quick quantification and accurate visualization of calcified coronary lesions, including the number of lesions, volume, calcium mass, and the Agatston Score. It can assess plaque burden in total or for individual main coronary arteries (RCA, LM, LAD, CX).

The tool is integrated within the syngo.via multimodality reading solution, which operates on a client-server platform, providing a comprehensive environment for advanced visualization, measurement, and evaluation of CT images. syngo.CT CaScoring utilizes standard or low-dose spiral or sequential CT scanning data sets. It features automatic highlighting of coronary calcifications and allows for user modification of the default threshold (130 HU) for score calculation. The software also provides an immediate comparison of the patient’s score to a healthy reference group, presenting it in a percentile graph and calculating the patient’s ‘Coronary Age’. It supports the creation of detailed paper reports that can include calcium scoring data, user-documented images, and relevant clinical information.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Quick quantification of calcified coronary lesions
  • Accurate visualization of calcified coronary lesions
  • Calculation of Agatston Score, volume, and calcium mass
  • Assessment of plaque burden in total and per coronary artery (RCA, LM, LAD, CX)
  • Automatic highlighting of coronary calcifications
  • User-modifiable threshold for score calculation (default 130 HU)
  • Comparison of patient score to healthy reference groups (e.g., MESA study)
  • Calculation of 'Coronary Age'
  • Built-in reporting engine for HTML, RTF, PDF, JPEG, MS Word reports
  • Integration with syngo.via multimodality reading solution

Use Cases

  • Prognostic indicator of atherosclerotic coronary heart disease risk
  • Risk assessment tool in diverse patient populations (women, multi-ethnic)
  • Pre-surgical workup before cardiothoracic surgery
  • Evaluation and documentation of calcified coronary lesions
  • Support for clinical decision-making in cardiology
  • Standardized reporting of calcium scoring data

What Physicians Need to Know

Cardiac CT/MRI Analysis
syngo.CT CaScoring is an evaluation software designed for quantifying calcified coronary lesions from CT images of the heart. It features automatic highlighting of coronary calcifications and utilizes a 3D segmentation algorithm for lesion evaluation. The software calculates Agatston equivalent, mass, and volume scores for individual coronary arteries (RCA, LM, LAD, CX) and provides total scores.
Coronary Artery Assessment
The primary function of syngo.CT CaScoring is the accurate visualization and rapid quantification of calcified coronary lesions. It enables the assessment of plaque burden both in total and for each of the main coronary arteries.
Heart Failure Risk Prediction
Assessment of coronary artery calcium burden serves as a prognostic indicator for a patient's risk of morbidity and mortality from atherosclerotic coronary heart disease. The tool aids in risk assessment and may offer a more effective prediction of Coronary Heart Disease compared to traditional risk evaluation methods. It also provides a 'Coronary Age' by comparing the patient's score to a healthy reference group, offering an easily understandable estimation of the coronaries' condition.
AHA/ACC Guideline Alignment
The tool's output, including Agatston scores and classification into score categories, is directly relevant to established management recommendations and aligns with guidelines for cardiovascular risk assessment. Bench testing of the automatic scoring algorithm has demonstrated adequate and acceptable performance for these critical aspects.
Physician Tip

syngo.CT CaScoring provides crucial quantitative data, including Agatston, volume, and mass scores, essential for assessing atherosclerotic coronary heart disease risk. The automatic highlighting and 3D segmentation features enhance efficiency and accuracy in identifying and quantifying lesions. The 'Coronary Age' feature is a valuable tool for patient communication, offering an intuitive understanding of their coronary health relative to a healthy population. Utilize the prognostic indicators to guide primary prevention strategies and reclassify cardiovascular risk, informing appropriate treatment decisions. Remember that the physician is responsible for correctly assigning lesions to their respective coronary arteries.

syngo.CT CaScoring is an integral component of the Siemens Healthineers CT Cardio-Vascular Engine, alongside applications like syngo.CT Cardiac Function, syngo.CT Coronary Analysis, and syngo.CT Vascular Analysis. It seamlessly integrates with syngo.via, a comprehensive software solution that supports the entire workflow from case preparation to results sharing, including viewing, manipulating, communicating, and storing medical images. The software facilitates the generation of detailed reports in various formats such as HTML, RTF, PDF, JPEG, and MS Word.

Details

Category Cardiology AI
Pricing Contact for pricing
  • One-time license purchase, contact vendor for details
  • A historical list price of $11,875.00 (with a 40% discount to $7,125.00) for 'CaScoring #1' was found in a NY.Gov document from 2018
DeploymentIntegrated with Siemens CT scanner systems; operates as a post-processing application on the multi-user syngo.via client/server platform.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

syngo.CT CaScoring (K221219) received FDA 510(k) clearance on May 17, 2022. It is classified as a Class II Computed Tomography X-Ray System (Product Code: JAK) and is intended as an image analysis software package for evaluating CT data sets to support physicians in evaluating and documenting calcified coronary lesions.

Integrations
EHR Not specified
Specialties Cardiology, Radiology

What the Web Says

syngo.CT CaScoring is a software package from Siemens Healthineers designed to quantify and visualize calcified coronary lesions from CT data. It supports physicians in evaluating and documenting coronary artery calcifications, which are a risk factor for coronary artery disease. The software calculates various scores, including the Agatston equivalent score, volume score, and calcium mass, and compares the patient's score to a healthy reference group. Recent studies suggest that the AI-powered version of syngo.CT CaScoring can significantly improve workflow efficiency and achieve accuracy comparable to radiologists, especially when used in a semi-automatic mode with expert review.

Overall: Positive

Strengths

  • Quick quantification and accurate visualization of calcified coronary lesions.
  • Calculates Agatston, volume, and mass scores, and provides a percentile graph for comparison to healthy reference groups.
  • Automatic highlighting of coronary calcifications with customizable thresholds.
  • Can significantly reduce evaluation time, especially with AI-powered automatic scoring.
  • High accuracy in identifying and quantifying coronary artery calcium, comparable to manual expert review.
  • Supports standardized image creation and reporting for clinical routine.

Limitations

  • Optimal results often recommend a semi-automatic approach with physician review to minimize potential errors.
  • Virtual non-contrast (VNC) images should not be used for scoring as they can lead to incorrect results.
  • Requires specific slice thickness and increment for Agatston equivalent scores.
  • Accuracy of measurements is primarily determined by the quality of the image data.
  • Some studies indicate a slight tendency for AI to underestimate extremely high Agatston scores (>1000).
  • Functionality for scoring lesions manually by drawing a region of interest (ROI) is only available for data from Siemens Healthineers CT scanners.

Based on reviews from: Siemens Healthineers, National Institutes of Health (NIH) - PMC, ResearchGate, Diagnostic and Interventional Cardiology (DAIC), accessdata.fda.gov, MDPI, NATAP, NY.gov, u56fdu7acbu533bu85acu54c1u98dfu54c1u885bu751fu7814u7a76u6240 u533bu7642u6a5fu5668u90e8, Innolitics

Last updated: 2026-07-19

Ratings & Reviews

No reviews yet. Be the first to review this tool!

Rate syngo.CT CaScoring

Clinical Value
Ease of Use
Integration
Support & Docs
Value for Money

Press & Coverage

RSNA Journals
Coronary Artery Disease Assessment via On-Site CT Fractional Flow Reserve in Patients Undergoing Transcatheter Aortic Valve Replacement | Radiology: Cardiothoracic Imaging - RSNA Journals
This peer-reviewed article from March 2024 discusses the use of syngo.CT CaScoring for computing Agatston scores in patients undergoing Transcatheter Aortic Valve Replacement (TAVR) to assess coronary artery disease. The software was used for semi-automated analysis of coronary calcification.
2024-03
PMC (PubMed Central)
Artificial intelligence-derived coronary artery calcium scoring saves time and achieves close to radiologist-level accuracy accuracy on routine ECG-gated CT - PMC
Published in December 2024, this peer-reviewed article investigates the efficiency and accuracy of AI-derived coronary artery calcium scoring, utilizing syngo.CT CaScoring VB60 for manual calcium score evaluation and comparison. The study found excellent agreement between AI and expert CACS.
2024-12
PLOS One
Calcium scoring during 18F-FDG PET/CT in cancer indications: Improving cardiovascular risk stratification and prevention | PLOS One
This peer-reviewed article from October 2025 details the use of syngo.CT CaScoringu2122 for coronary calcium score evaluation in patients undergoing 18F-FDG PET/CT for cancer investigation, aiming to improve cardiovascular risk stratification. The assessment was performed visually and using the Siemens Healthineers software.
2025-10
Siemens Healthineers USA
syngo.CT CaScoring u2013 Siemens Healthineers USA
This product page provides an overview of syngo.CT CaScoring, highlighting its capabilities for quick quantification and accurate visualization of calcified coronary lesions, including Agatston Score and coronary age calculation. It emphasizes its role in enhancing cardiovascular diagnostics.
unknown
FDA.report
Siemens Medical Solutions USA, Inc. January 04, 2024 u2013 FDA.report
A regulatory announcement from January 2024 indicates that syngo.CT CaScoring was added as a fourteenth application to syngo.CT Applications and its export function was extended to include a DICOM Structured Report. This document outlines FDA clearance for updates to Siemens Healthineers' CT applications.
2024-01
PMC (PubMed Central)
Thickness of epicardial and pericoronary adipose tissue measured using 128-slice MSCT as predictors for risk of significant coronary artery diseases - PMC
This peer-reviewed article describes the use of syngo.CT CaScoring for the assessment of coronary artery calcium score (CACS) in patients to determine the risk of significant coronary artery disease. The software automatically classified lesions based on size and density.
unknown
Siemens Healthineers
Time to Rethink the Calcium Scoring Workflow - Siemens Healthineers
This article from November 2018 discusses syngo.CT CaScoring's role in providing a quantitative measure of coronary calcium and highlights Siemens Healthineers' innovative approach to tackling traditional restrictions in acquisition methods for calcium quantification. It mentions the potential for dose optimization.
2018-11
Siemens Healthineers USA
syngo.via - Siemens Healthineers USA
This page describes syngo.via as a multimodality reading solution that includes syngo.CT CaScoring for quantifying coronary calcifications and calculating coronary age. It emphasizes the integration of syngo.CT CaScoring within the broader syngo.via platform for efficient imaging workflows.
unknown

Videos

Product demos, reviews, and walkthroughs for syngo.CT CaScoring.

No videos found. Search YouTube directly

View all on YouTube

Frequently Asked Questions

syngo.CT CaScoring is an image analysis software designed to evaluate non-contrast cardiac CT scans for calcified coronary lesions. It integrates into the syngo.via platform, allowing for automatic highlighting and quantification of calcifications, calculating Agatston, mass, and volume scores for individual arteries and total scores. This automation can significantly reduce the time spent on manual segmentation, with studies showing up to a 60% time saving compared to manual review, while maintaining excellent accuracy.
syngo.CT CaScoring has received FDA 510(k) clearance, indicating it has been found substantially equivalent to predicate devices. The software's automated scoring algorithm has undergone bench testing and validation, demonstrating adequate and acceptable performance for Agatston scores and classification into risk categories. This regulatory clearance provides assurance regarding its safety and effectiveness as a medical device.
Yes, other AI-powered calcium scoring solutions exist, such as CACScore Doc and AVIEW CAC. While syngo.CT CaScoring offers automated segmentation and scoring with high agreement to expert radiologists, comparisons often highlight similar accuracy levels across validated AI models. The choice may depend on integration with existing CT scanners and imaging platforms, as syngo.CT CaScoring is part of the Siemens Healthineers syngo.via ecosystem.
While highly accurate, AI in CACS, including syngo.CT CaScoring, can have limitations. The Agatston score itself is influenced by factors like image resolution, slice thickness, and calcium density. Although AI reduces inter-observer variability, a semi-automatic approach with expert review is often recommended to minimize potential errors, particularly in complex cases.
Specific pricing details for syngo.CT CaScoring are typically provided by Siemens Healthineers representatives, as it can be offered as an option or upgrade within the syngo.via platform. Licensing models can be flexible, with syngo.via offering options like a 'Flex Plan' that adapts to budget and clinical focus. For larger institutions, server clustering options may provide cost efficiencies.
syngo.CT CaScoring is primarily designed for evaluating CT data sets from spiral or sequential CT scans, often acquired with ECG triggering or retrospectively gated spiral scans for optimal cardiac imaging. While some AI models for CACS have been trained on non-gated chest CTs, the current standard of practice for accurate Agatston scoring typically involves dedicated cardiac CT scans. Using non-dedicated or non-gated scans for CACS may introduce variability, and virtual non-contrast images should not be used for calcium score calculation.
syngo.CT CaScoring quantifies coronary artery calcium burden, which is a significant prognostic indicator for atherosclerotic coronary heart disease. By providing Agatston, mass, and volume scores, and comparing the patient's score to a healthy reference group (e.g., MESA study) to determine 'coronary age,' it aids physicians in assessing cardiovascular risk. This information supports clinical decision-making for preventive therapy initiation and pre-surgical workups.

Related Tools

EchoMD AutoEF
Caption Health (formerly Bay Labs, now part of GE HealthCare)
Cardiology AI
EchoMD AutoEF is an FDA-cleared AI software that automates the selection of echocardiogram clips and calculates left ventricular ejection fraction (EF), enhancing efficiency and accuracy in cardiac assessments.
ECG-AI Cardiac Amyloidosis (CA) 12-Lead Algorithm
Anumana, Inc.
Cardiology AI
An AI algorithm for screening cardiac amyloidosis using standard 12-lead ECGs.
DEEPVESSEL Plaque
Keya Medical Technology Co., Ltd.
Cardiology AI
An AI software platform for coronary plaque analysis and quantification from CT angiography.
WatchMate Software
Anumana, Inc.
Cardiology AI
Anumana is an AI-driven health technology company from nference, developing and delivering ECG algorithms enabling early diagnosis and intervention.
syngo.CT Coronary Cockpit
Siemens Healthineers
Cardiology AI
syngo.CT Coronary Cockpit is an AI-powered software tool by Siemens Healthineers for efficient and accurate CT coronary angiography analysis.
HeartLung AI-CVD®
HeartLung Corporation
Cardiology AI
HeartLung AI-CVD® is an FDA-cleared AI-powered quantitative imaging tool that provides automated CT-derived measurements for assessing cardiovascular and multisystem risks opportunistically.

See all Cardiology AI tools →

More from Siemens Medical Solutions USA

ACUSON Sequoia Diagnostic Ultrasound System
Siemens Medical Solutions USA
Radiology & Imaging AI
The ACUSON Sequoia Diagnostic Ultrasound System by Siemens Healthineers is a premium platform featuring BioAcoustic imaging, InFocus technology, and AI-powered tools to deliver consistent, high-resolution ultrasound imaging across diverse patient types and clinical applications.
AI Rad Companion (Engine)
Siemens Medical Solutions USA
Radiology & Imaging AI
Siemens AI-Rad Companion (Engine) is an FDA-cleared, AI-powered, cloud-based platform that streamlines radiology workflows and enhances diagnostic precision through automated image post-processing and structured reporting across multiple modalities.
AI-Rad Companion (Musculoskeletal)
Siemens Medical Solutions USA
Radiology & Imaging AI
AI-Rad Companion (Musculoskeletal) by Siemens Medical Solutions USA is an FDA-cleared AI-powered image processing software for quantitative and qualitative analysis of musculoskeletal conditions from CT DICOM images, supporting radiologists and physicians in diagnostic evaluation.
AI-Rad Companion Engine
Siemens Medical Solutions USA
Radiology & Imaging AI
The AI-Rad Companion Engine is an AI-powered, cloud-based platform by Siemens Medical Solutions USA that automates post-processing and enhances diagnostic precision in medical image interpretation across multiple modalities.

View company profile →

Suggest an Edit → | Last Verified: 2026-04-19 | First Added: 2026-04-19
AI Tool Finder
AI-powered search. Results may not be comprehensive.