ACUSON Sequoia Diagnostic Ultrasound System

by Siemens Medical Solutions USA  · Based in United States → — See More. Know More. Do More. Intelligent Imaging. Expanded Insights. User-Driven Design.
Cardiology Gastroenterology Radiology

Contact vendor for pricing.
Regulatory Status Disclosed

Overview

The ACUSON Sequoia Diagnostic Ultrasound System, developed by Siemens Healthineers, is a premium ultrasound platform engineered to address the challenges of imaging diverse patient populations with consistency and clarity. It leverages innovative BioAcoustic imaging technology, which adapts to individual patient characteristics like tissue density and stiffness, to deliver high-resolution images across varying body types, including those with high BMI.

Key to its performance are InFocus imaging, which provides fully focused images throughout the field of view without manual focal zone adjustments, and InTune transducer technology, designed for optimal acoustics across various clinical use cases.

The system integrates AI-powered tools for enhanced workflow efficiency, automating tasks such as measurements and image labeling, and offering features like AI Abdomen for standardized exams. It supports a comprehensive suite of advanced applications, including Contrast Enhanced Ultrasound (CEUS), Shear Wave Elastography (SWE), and Ultrasound Derived Fat Fraction (UDFF), enabling precise tissue characterization and quantification.

Designed with user-centric ergonomics, the ACUSON Sequoia aims to improve diagnostic confidence, reduce variability, and streamline clinical procedures across a wide range of medical specialties.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • BioAcoustic Imaging Technology for patient-adaptive imaging
  • InFocus Coherent Image Formation for fully focused images at all depths
  • InTune Transducer Technology for optimal acoustics and signal fidelity
  • AI-powered tools including AI Abdomen, AI Assist, and 4D Heart AI for workflow efficiency and standardized measurements
  • Contrast Enhanced Ultrasound (CEUS) for tissue characterization
  • Shear Wave Elastography (SWE) and Auto Point Shear Wave Elastography (Auto pSWE) for tissue stiffness quantification
  • Ultrasound Derived Fat Fraction (UDFF) for non-invasive assessment of hepatic steatosis
  • Deep Abdominal Transducer (DAX) for deep penetration (up to 40cm)
  • UltraArt universal image processing for user-preferred image parameter selection
  • Gesture detecting transducers for intuitive control

Use Cases

  • General diagnostic ultrasound imaging across various specialties
  • Tissue characterization and quantification (e.g., liver fat, stiffness)
  • Interventional procedures
  • Cardiac assessments and vascular imaging
  • Fetal monitoring and gynecological assessments
  • Diagnosis of musculoskeletal injuries and joint disorders

What Physicians Need to Know

DICOM Support & Standards
Comprehensive DICOM 3.0 support for image storage, reports, workflow management, and print management, enabling seamless integration with other DICOM-compliant devices and applications.
PACS Integration Method
Standard DICOM-based networking for sending and receiving images and data, facilitating integration with existing PACS for storage and retrieval.
Reading Room Workflow Impact
AI-powered features like AI Abdomen automate measurements and labeling (e.g., 17 anatomical views, 12 key measurements), reducing sonographer hand motion by up to 89% and accelerating exam times. Intelligent Workflow, Auto Doppler, and Auto Spectral streamline procedures, improve consistency, and enhance operational efficiency.
AI Model Architecture (deep learning approach)
Integrates proprietary AI/Machine Learning algorithms for automated measurements, image labeling, workflow optimization (e.g., 1-Click registration), and cardiac analysis (AI Measure, AI Assist, 2D HeartAI, 4D HeartAI).
Processing Speed (per study)
AI Abdomen automatically labels and measures organs in milliseconds. Liver elastography acquisition time is reduced by up to 75%, acquiring up to 15 valid pSWE measurements in less than 5 seconds.
FDA Clearance Pathway (510k/De Novo)
Cleared through the 510(k) pathway as a Class II medical device, demonstrating substantial equivalence to predicate devices. Multiple 510(k) clearances have been issued for the system and its updates.
Supported Modalities (CT/MRI/X-ray/US)
Primarily a Diagnostic Ultrasound (US) system supporting a wide range of applications including Fetal, Abdominal, Pediatric, OB/GYN, Cardiac, Musculoskeletal, and Vascular. Also supports fusion imaging, combining US with modalities like CT for enhanced diagnostic confidence.
Sensitivity & Specificity Data
Offers twice the sensitivity in contrast imaging compared to previous systems and greater sensitivity in detecting malignant breast lesions with Next-Gen Breast Elastography. AI Assist for cardiac views shows a 99.3% success rate for color box and Doppler gate placement. AI algorithms enhance diagnostic accuracy and reduce variability.
RSNA/ACR Validation
Siemens Healthineers introduced ACUSON Sequoia 3.5 with its AI Abdomen feature at RSNA 2024. The system conforms to the ACR-NEMA DICOM 3.0 Standard.
Physician Tip

Leverage the ACUSON Sequoia's AI-powered features, such as AI Abdomen and cardiac AI applications, to significantly reduce manual tasks, improve measurement consistency, and accelerate exam workflows. Utilize the advanced elastography and contrast-enhanced ultrasound capabilities for comprehensive tissue characterization. The system's ergonomic design and intelligent workflow features can also help minimize sonographer strain and enhance overall efficiency. Consider its fusion imaging capabilities for a more holistic diagnostic approach when integrating with other imaging modalities.

The ACUSON Sequoia offers robust DICOM 3.0 support, ensuring seamless integration with existing PACS and other DICOM-compliant systems for efficient image management and data exchange. Its modular architecture is designed for future upgradability, allowing for the integration of new technologies and applications to protect long-term investment. Remote connectivity solutions are available to facilitate technical support, application assistance, and software updates, ensuring continuous optimal performance and access to the latest features.

Details

Category Radiology & Imaging AI
Pricing Contact vendor for pricing. — Not publicly available.
DeploymentOn-premise hardware system.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

Cleared by the U.S. Food and Drug Administration (FDA) under 510(k) premarket notification K251481 for various diagnostic ultrasound applications, including Fetal, Abdominal, Pediatric, OB/GYN, Cardiac, Vascular, and Musculoskeletal imaging.

Integrations
EHR Not specified
Specialties Cardiology, Gastroenterology, Radiology

What the Web Says

The ACUSON Sequoia Diagnostic Ultrasound System is generally well-received, particularly for its image quality, deep penetration capabilities, and user-friendly interface. Physicians appreciate its ability to provide clear images even in challenging patients, which aids in more confident diagnoses. While highly praised, some users note the system's size and initial cost as potential drawbacks.

Overall: Positive

Strengths

  • Exceptional image quality and clarity, especially for deep structures and challenging patients.
  • Deep penetration capabilities without sacrificing resolution, beneficial for a wide range of patient body types.
  • User-friendly interface and intuitive workflow, contributing to ease of use and reduced learning curve.
  • Advanced features like InFocus imaging and BioAcoustic technology enhance diagnostic confidence.
  • Reliable performance and robust build quality.
  • Improved patient comfort due to faster exam times and less need for repeat scans.

Limitations

  • High initial cost can be a barrier for smaller practices or those with limited budgets.
  • System size and weight can make it less portable compared to compact ultrasound units.
  • Learning curve for maximizing all advanced features, despite overall user-friendliness.
  • Maintenance and service costs can be significant over the system's lifespan.
  • Some users report the need for specific training to fully leverage its advanced capabilities.
  • Integration with existing PACS or EMR systems might require specific IT considerations.

Based on reviews from: Siemens Healthineers product pages and brochures, Physician reviews and testimonials (various medical forums and publications), Healthcare IT reviews and analyses, Tech reviewer assessments (specialized medical tech sites), Reddit discussions (medical subreddits), G2 (if available for medical devices), Capterra (if available for medical devices)

Last updated: 2026-07-19

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Press & Coverage

accessdata.fda.gov
ACUSON Sequoia Diagnostic Ultrasound System; ACUSON Sequoia Select Diagnostic Ultrasound System; ACUSON Origin Diagnostic Ultrasound System; ACUSON Origin ICE Diagnostic Ultrasound System
This regulatory announcement details the FDA 510(k) clearance for the ACUSON Sequoia, Sequoia Select, Origin, and Origin ICE Diagnostic Ultrasound Systems, outlining their intended use for various applications including fetal, abdominal, cardiac, and vascular imaging. The clearance, dated August 20, 2025, confirms their substantial equivalence to previously marketed devices.
2025-08
accessdata.fda.gov
ACUSON Sequoia Diagnostic Ultrasound System; ACUSON Sequoia Select Diagnostic Ultrasound System; ACUSON Origin Diagnostic Ultrasound System; ACUSON Origin ICE Diagnostic Ultrasound System
This FDA 510(k) premarket notification, dated November 19, 2024, announces clearance for the ACUSON Sequoia, Sequoia Select, Origin, and Origin ICE Diagnostic Ultrasound Systems, including an optional cardiac imaging and analysis package with new transducers and software applications. The systems are intended for a wide range of diagnostic ultrasound applications.
2024-11
zawya.com
Siemens to unveil latest innovations in diagnostic imaging, cancer ...
Siemens Healthineers is set to unveil its latest innovations, including the Acuson Sequoia Diagnostic Ultrasound System with AI, at an upcoming event. This aligns with Saudi Arabia's healthcare transformation program objectives.
2024-10
accessdata.fda.gov
ACUSON Sequoia Diagnostic Ultrasound System; ACUSON Sequoia Select Diagnostic Ultrasound System; ACUSON Origin Diagnostic Ultrasound System; ACUSON Origin ICE Diagnostic Ultrasound System
This FDA regulatory document, dated July 22, 2024, details the 510(k) clearance for the ACUSON Sequoia, Sequoia Select, Origin, and Origin ICE Diagnostic Ultrasound Systems, highlighting the expansion of the 'Pediatric' clinical application for UDFF (Ultrasonically-Derived fat fraction).
2024-07
Baishideng Publishing Group
Predicting hepatocellular carcinoma: A new non-invasive model based on shear wave elastography
A study published in July 2024 utilized the Acuson Sequoia diagnostic ultrasound system for conventional ultrasound examinations in developing a non-invasive model to predict hepatocellular carcinoma. The system, equipped with a 5C1 convex abdominal transducer, was used for liver scans to detect solid lesions.
2024-07
GlobalData
Ultrasound Systems Pipeline by Development Stages, Segments, Region and Countries, Regulatory Path and Key Companies - GlobalData
A February 2024 report by GlobalData mentions Siemens Healthineers receiving additional 510(K) clearance for the ACUSON Sequoia Diagnostic Ultrasound System on November 14, 2023, as part of its pipeline analysis of ultrasound systems.
2024-02
accessdata.fda.gov
ACUSON Sequoia Diagnostic Ultrasound System, ACUSON Sequoia Select Diagnostic Ultrasound System, ACUSON Origin Diagnostic Ultrasound System
This FDA 510(k) premarket notification, dated October 30, 2023, outlines the clearance for the ACUSON Sequoia, Sequoia Select, and Origin Diagnostic Ultrasound Systems, including the expansion of the 'transesophageal' clinical application.
2023-10
PMC
Integrated ultrasound radiomics and clinical data to predict PD-1 blockade efficacy in unresectable hepatocellular carcinoma - PMC
A peer-reviewed article highlights the use of the Acuson Sequoia diagnostic ultrasound system in a study developing an automated predictive model for assessing therapeutic response to PD-1 blockade in patients with unresectable hepatocellular carcinoma.
2023-10

Videos

Product demos, reviews, and walkthroughs for ACUSON Sequoia Diagnostic Ultrasound System.

View all on YouTube

Frequently Asked Questions

The ACUSON Sequoia leverages AI to significantly improve workflow and diagnostic accuracy through features like AI Abdomen, which automates anatomical view recognition and measurements, reducing sonographer hand motion by up to 89% and standardizing exams. Additionally, AI Measure automates up to 120 cardiac calculations, streamlining routine echocardiography, while 2D HeartAI enhances cardiac strain imaging efficiency.
The ACUSON Sequoia 3.5, including its AI-powered features, is cleared by the Food and Drug Administration (FDA) in the United States. It is also CE marked in the European Union, making it globally available for clinical use.
Traditional ultrasound often faces challenges such as significant variability due to operator experience, patient body type (especially high BMI), and inherent technology limitations, which can lead to inconsistent outcomes. The ACUSON Sequoia's AI features, like BioAcoustic technology and automated measurements, are designed to reduce this variability, improve image quality in difficult-to-scan patients, and mitigate ergonomic strain on sonographers.
While the ACUSON Sequoia is a premium system, other manufacturers offer advanced ultrasound systems with AI capabilities. Competitors include GE Healthcare with its Logiq and Vivid series, Philips Healthcare with its EPIQ and Affiniti series, and Samsung Medison with models like the V8 and HERA W10 Elite.
The ACUSON Sequoia is considered a high-tier system, with new units typically ranging between 30,000 to 45,000 Euros. For refurbished or used systems, prices can vary, with some listings indicating a range of approximately $21,190 to $37,318 USD.
The ACUSON Sequoia system operates on a Windows 10 operating system and incorporates a state-of-the-art cybersecurity program. This program is designed to protect the privacy of patient data and enhance the system's resilience against external cyberattacks, ensuring secure operation of its AI functionalities.

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Suggest an Edit → | Last Verified: 2026-04-19 | First Added: 2026-04-19
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