Products

ART-Plan
TheraPanacea
Oncology AI
ART-Plan™ by TheraPanacea is an FDA-cleared, AI-powered software for high-precision radiotherapy, optimizing cancer treatment from preparation to follow-up with automated contouring, image fusion, and adaptive planning.

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About Therapanacea SAS

TheraPanacea SAS is a French healthcare AI company specializing in advanced software solutions designed to revolutionize cancer care, particularly in the field of radiotherapy. Their flagship product, ART-Plan™, is an AI-powered suite that optimizes various stages of the radiation oncology workflow, from treatment preparation to follow-up. This comprehensive system incorporates AI-based automatic delineation, intelligent image fusion (SmartFuse), MR-based pseudo-CT generation, and AI-enhanced tools for efficient and precise adaptive planning (AdaptBox). The aim is to standardize care, reduce inter-operator variability, and improve therapeutic accuracy, ultimately leading to better patient outcomes. ART-Plan™ is currently deployed in over 60 cancer centers across Europe, Africa, the Middle East, and the US, contributing to the care of more than 60,000 patients annually, with some sources indicating its use in over 100 centers globally.

In addition to radiotherapy solutions, TheraPanacea develops ART-Omics™, an AI-powered multi-modality biomarker discovery platform. This platform is designed to assist pharmaceutical companies in accelerating clinical research by leveraging AI for biomarker identification and seamlessly integrating these insights into clinical workflows as certified medical devices. The company’s core mission is to harness artificial intelligence, medical imaging, and advanced mathematics to drive innovation across healthcare. Their focus areas include improving treatment selection, planning, delivery, and outcomes, as well as patient stratification, with an expanding interest in neurology and other disease states. TheraPanacea’s solutions are geared towards delivering predictive, evidence-driven, and adaptive treatment planning, with the ultimate goal of enhancing the quality of life for cancer patients by enabling smarter treatment plans and reducing toxic side effects.

Focus Areas

AI-powered radiotherapy planning automatic contouring image fusion adaptive radiotherapy pseudo-CT generation AI-powered biomarker discovery cancer care neurosciences AI precision medicine

Business Intelligence

Key InvestorsLa French Tech, Biogen, EIT Health, Bpifrance, European Research Council
PartnershipsBrainlab, LAP, Stingray Healthcare, DYN'R Medical Systems, 2CRSi
TechnologyDeep Learning, AI-based software platform, web-based solution, GPU workloads, multi-modal visualization, rigid and deformable registration
FDA Clearances4 cleared products (estimated)

What Physicians Need to Know

AI-Powered Radiotherapy Planning
TheraPanacea's ART-Planu2122 is an intelligent software suite that optimizes every step of the radiotherapy treatment process, from preparation to follow-up, leveraging state-of-the-art AI, data science, and medical image processing.
Automatic Contouring (Annotateu2122)
Provides fully automatic delineation of over 200 CT and MRI-based organs at risk (OARs) and lymph nodes within 2-3 minutes, with accuracy comparable to clinical experts, adhering to the latest consensus contouring guidelines.
Advanced Image Fusion (SmartFuseu2122)
Offers AI-powered rigid and elastic fusion capabilities, including the management of 4D-CT and real-time deformation of contours for faster replanning.
Adaptive Radiotherapy (AdaptBoxu2122)
Delivers decision-making support for adaptive radiotherapy by utilizing AI to generate enhanced pseudo-CT from CBCT, auto-contouring, and recalculating/comparing dose metrics to the active treatment plan.
Pseudo-CT Generation (MR-Boxu2122 & AdaptBoxu2122)
Generates MRI-based pseudo-CT for MR-only and MR-guided radiotherapy to avoid registration errors and improve patient comfort, and also generates pseudo-CT from CBCT images.
AI-Powered Biomarker Discovery (ART-Omicsu2122)
The first AI-powered, plug-n-play radiomics platform combining unsupervised biomarker discovery with clinical domain knowledge for advanced diagnosis, prognosis, and disease monitoring, particularly in neurosciences.
Zero-Click AI Automation
Their platform offers zero-click AI automation for high-precision radiotherapy, leading to significant time savings (up to 90%) for dosimetrists, RTTs, and radiation oncologists.
Web-Based & 'Plug and Play' Platform
ART-Planu2122 is a web-browser based, scalable, and modular platform, accessible from any computer connected to the clinic's network. It's a 'Plug and Play' solution, meaning it's fully pre-trained and requires no local data for initial setup.
Extensive Clinical Adoption & Evidence
The ART-Planu2122 platform is in clinical use in over 150 departments worldwide, with 1 out of 4 radiotherapy patients in France being auto-contoured with their solution, demonstrating widespread acceptance and proven performance.
Physician Tip

For physicians, TheraPanacea's solutions, particularly ART-Planu2122, offer a transformative approach to radiotherapy. You can expect significant time savings in contouring (up to 93% and as fast as 3 minutes for full-body delineation), allowing more focus on complex treatment planning and patient interaction. The AI-powered automatic contouring provides expert-level accuracy and standardization, reducing inter-clinician variability and enhancing the consistency and reliability of treatment plans. The ability to generate pseudo-CTs from MRI and CBCT images streamlines workflows and improves patient comfort by facilitating MR-only radiotherapy. Furthermore, the AdaptBoxu2122 module provides objective metrics for adaptive therapy, aiding in crucial replanning decisions. The 'Plug and Play' nature ensures easy integration into existing workflows without the need for extensive data provision or training, and the web-based platform offers accessibility from anywhere within your clinic's network. This technology ultimately aims to deliver more precise, efficient, and personalized cancer care, backed by AI models trained on international guidelines and expert data.

TheraPanacea's ART-Planu2122 is designed for seamless integration with existing treatment planning systems (TPS) and PACS through DICOM exchange. They also have established partnerships, such as with Brainlab, to offer enhanced segmentation choices for clinicians. While currently server-based within the internal clinic network, future plans include cloud-based availability for further optimized and streamlined radiotherapy workflows.

Products by Therapanacea SAS

1 product in the directory

ART-Plan
TheraPanacea
Oncology AI
ART-Plan™ by TheraPanacea is an FDA-cleared, AI-powered software for high-precision radiotherapy, optimizing cancer treatment from preparation to follow-up with automated contouring, image fusion, and adaptive planning.

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Press & Coverage

Therapanacea
Quantitative and qualitative evaluation of an automatic GTV contouring tool in pre-radiotherapy MRI in glioblastoma treatment
This press release from February 2026 announces the evaluation of an automatic GTV contouring tool for glioblastoma treatment using pre-radiotherapy MRI.
2026-02
Therapanacea
TheraPanacea appoints new Chief Technology Officer
TheraPanacea announced the appointment of a new Chief Technology Officer in February 2026.
2026-02
Therapanacea
TheraPanacea receives CE mark for AdaptBox adaptive planning suite
In January 2026, TheraPanacea received CE mark approval for its AdaptBox adaptive planning suite.
2026-01
Therapanacea
TheraPanacea achieves ISO 13485 quality certification
TheraPanacea announced in December 2025 that it achieved ISO 13485 quality certification.
2025-12
Therapanacea
TheraPanacea expands partnership with Gustave Roussy on clinical validation
In November 2025, TheraPanacea expanded its partnership with Gustave Roussy for clinical validation.
2025-11
Therapanacea
TheraPanacea adds Milan clinical validation site
TheraPanacea announced in October 2025 the addition of a clinical validation site in Milan.
2025-10
Therapanacea
TheraPanacea opens new R&D center to scale clinical AI research
In September 2025, TheraPanacea opened a new R&D center to scale its clinical AI research efforts.
2025-09
Therapanacea
TheraPanacea to present sixteen abstracts at ESTRO 2026
TheraPanacea is scheduled to present sixteen abstracts at ESTRO 2026.
2026-04

Frequently Asked Questions

TheraPanacea offers the ART-Planu2122 suite, which includes modules like Annotateu2122 for automatic contouring of organs at risk and lymph nodes, SmartFuseu2122 for AI-initiated rigid and deformable image fusion, MR-Boxu2122 for generating pseudo-CTs from MR images, and AdaptBoxu2122 for AI-enhanced adaptive planning and pseudo-CT generation from CBCT images. These tools aim to optimize and standardize the radiotherapy treatment workflow.
TheraPanacea develops the ART-Omicsu2122 platform for AI-based multi-modality biomarker discovery, which helps pharmaceutical companies accelerate clinical research and integrate biomarkers into clinical workflows for personalized treatment. Beyond oncology, they also apply AI in neurosciences, notably through a partnership with Biogen, to analyze medical imaging and multimodal data for personalized medicine in neurological diseases like Alzheimer's and Multiple Sclerosis.
TheraPanacea's ART-Planu2122 software is CE-marked (Class IIb) and has received FDA 510(k) clearance, as well as TGA clearance. The company adheres to regulatory requirements such as registration and listing, labeling, medical device reporting, and quality system regulations (21 CFR Part 820) for its devices.
TheraPanacea collaborates with various industrial and clinical partners to enhance its offerings and expand its market presence. Notable industrial partnerships include Brainlab and LAP for integrating AI-powered segmentation tools, and DYN'R Medical Systems for US market penetration. Clinical collaborations with institutions like Gustave Roussy, Acibadem University, and Stingray Healthcare facilitate product development, testing, and large-scale adoption of AI solutions in radiotherapy.
Founded in 2017, TheraPanacea has demonstrated significant growth and stability, having raised over $19 million in funding. Their ART-Planu2122 platform is utilized in over 150 radiotherapy departments worldwide, with more than 1.5 million patients treated, indicating a strong and expanding market presence in AI-powered cancer care.
TheraPanacea's AI-powered solutions, such as Annotateu2122, significantly reduce manual contouring time by up to 93%, generating expert-like contours for over 250 organs at risk and lymph nodes in minutes. This automation, combined with precise image fusion and adaptive planning tools, helps standardize delineation practices, reduce inter-clinician variability, and streamline clinical workflows, ultimately leading to more efficient and accurate treatment delivery.
While specific details on support tiers are not publicly detailed, TheraPanacea offers a web-based, 'Plug and Play' software solution designed for easy integration into existing hospital IT infrastructures. They provide user manuals with their devices and can be contacted via email for inquiries, including product demonstrations and general support.

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