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PrecisePK
PrecisePK
Clinical Decision Support & Reference
PrecisePK is a leading Bayesian Therapeutic Drug Monitoring (TDM) software that uses AI and advanced algorithms to provide precise drug dosing regimens and predict drug levels for various patient populations, aiding clinicians and pharmacists in optimizing patient care.

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About PrecisePK

PrecisePK is a leading healthcare AI company specializing in therapeutic drug monitoring (TDM) software, leveraging Bayesian model-informed precision dosing (MIPD) to optimize patient care. For physicians, this means access to a sophisticated tool that provides individualized pharmacokinetic calculations, enabling more accurate and efficient drug dosing regimens. The platform is designed to simplify the complex process of dose optimization by incorporating patient-specific data, PK/PD models, machine learning, and cloud computing. It offers real-time bedside assistance, predictive analytics, and a therapeutic analytics dashboard, aiming to streamline clinical workflows and reduce the guesswork in daily practice.

The software is particularly valuable for drugs with narrow therapeutic indices, such as vancomycin, where it facilitates compliance with the 2020 Vancomycin AUC Guidelines by providing AUC-based dosing recommendations. Beyond vancomycin, PrecisePK offers drug models for over 20 medications, extending its utility across various therapeutic areas including infectious diseases, oncology (e.g., busulfan, methotrexate), cardiology, neurology (e.g., tacrolimus), and transplantation and immunosuppressive therapy (e.g., cyclosporine, infliximab). It also includes an Acute Kidney Injury (AKI) predictor, further enhancing patient safety and outcomes through data-driven individualized dosing. PrecisePK’s robust Bayesian algorithms continuously refine existing models based on an institution’s specific patient population, maximizing target attainment and improving clinical efficacy and safety.

Focus Areas

Therapeutic Drug Monitoring (TDM) Model-Informed Precision Dosing (MIPD) Bayesian Dosing Pharmacokinetics Acute Kidney Injury (AKI) prediction Vancomycin AUC dosing Methotrexate dosing Cyclosporine dosing Infliximab dosing infectious diseases oncology cardiology neurology

Business Intelligence

PartnershipsUC San Diego Health, Pacific University Oregon, Hospital Universitari Mútua Terrassa (Spain), Wolters Kluwer (Sentri7), Sanford Guide, VA VISN 22: Desert Pacific Healthcare Network, Chung-Ang University Healthcare System (South Korea), Korea University System (South Korea), Asan Medical Center (South Korea), Kyung Hee University (South Korea), Escuela de Química y Farmacia (Chile), Clínica Andes Salud Concepción (Chile), Servicio de Salud Talcahuano (Chile), Maza University (Argentina), Luisadas Saude Health (Portugal), Unidade de Saúde Local da Guarda (ULSG) (Portugal)
TechnologyCloud-native (web-based platform), Bayesian algorithms, machine learning, PK/PD models, real-time bedside assistance, therapeutic analytics dashboard, AKI predictor, EHR integration (Cerner, Epic)

What Physicians Need to Know

Therapeutic Drug Monitoring (TDM) & Model-Informed Precision Dosing (MIPD)
PrecisePK specializes in TDM and MIPD, leveraging Bayesian algorithms and machine learning to provide precise, individualized dosage recommendations. This approach allows for tailored treatment strategies based on patient-specific pharmacokinetic parameters, moving beyond traditional population-based dosing.
Bayesian Dosing & Pharmacokinetics
The core of PrecisePK's technology is Bayesian forecasting, which uses population PK parameters as a prior and a patient's observed serum concentrations to calculate individualized PK profiles. This enables accurate prediction of future AUC or serum levels with as little as one blood draw, optimizing dosing regimens and reducing toxicity.
Vancomycin AUC Dosing
PrecisePK offers highly accurate vancomycin AUC dosing, fully compliant with the IDSA/ASHP 2020 guidelines. It is validated as one of the most accurate tools for predicting vancomycin AUC in critically ill patients, allowing for a transition from trough-based to AUC-based targets.
Methotrexate Dosing
The platform includes tailored models for methotrexate, empowering oncology care with precision dosing strategies for patients with conditions like Osteosarcoma, Acute Lymphoblastic Leukemia (ALL), Lymphoma, and Rheumatoid Arthritis, aiming to optimize therapeutic outcomes and minimize adverse effects.
Cyclosporine Dosing
PrecisePK provides Bayesian forecasting and TDM models for cyclosporine, a vital immunosuppressant. These models are designed for adult and pediatric patients undergoing heart, lung, and kidney transplantation, enabling tailored dosages to optimize outcomes and reduce adverse effects.
Infliximab Dosing
PrecisePK offers distinct models for infliximab, addressing diverse immunosuppressive needs across autoimmune conditions such as Ulcerative colitis, Crohn's disease, Ankylosing spondylitis, Rheumatoid arthritis, and Psoriasis arthritis, guiding dose adjustments with high accuracy.
Acute Kidney Injury (AKI) Prediction
The software incorporates real-time monitoring and data-driven analytics for AKI management, helping to predict and potentially reduce the incidence of nephrotoxicity associated with drug dosing.
Special Populations & Comprehensive Drug Models
PrecisePK provides flexible models for various patient populations, including neonates, pediatrics, obese, critically ill, and post-cardiac surgery patients. It encompasses over 20 medications across therapeutic areas like infectious diseases, oncology, cardiology, and neurology.
Key Differentiators
PrecisePK stands out due to its 30+ years of clinical experience (formerly TDMS), user-friendly web-based interface requiring minimal training, and its ability to achieve precise dosing with a single serum level. It also offers flexible customer optimization, multilingual support, and robust validation in academic and clinical settings.
Technology Stack
The platform is built on advanced Bayesian algorithms, machine learning (AI), and comprehensive population pharmacokinetic (PPK) models. It utilizes two-compartment kinetics models for drugs like vancomycin, ensuring high accuracy and adaptability to individual patient characteristics.
Physician Tip

For physicians, PrecisePK offers a powerful tool to enhance patient safety and optimize therapeutic outcomes. Its individualized, data-driven dosing recommendations, especially for narrow therapeutic index drugs, can significantly reduce the risk of toxicity and improve efficacy. The user-friendly interface and ability to integrate with EHRs streamline workflow, saving valuable time. By leveraging Bayesian analysis, physicians can make more informed decisions with fewer blood draws, leading to reduced costs and improved patient comfort. The comprehensive models for special populations and a wide array of medications ensure that even complex cases can receive precise, tailored care. Consider utilizing PrecisePK to move towards a more personalized and efficient approach to drug management in your practice.

PrecisePK offers robust integration capabilities with various Electronic Health Record (EHR) systems. Notably, it is fully integrated with the Epic EHR platform via the App Orchard Marketplace, allowing for secure and automatic import of patient data like medication orders, vancomycin levels, and serum creatinine. PrecisePK also collaborates with Wolters Kluwer to offer an integrated Bayesian dosing solution through Sentri7 Pharmacy, supporting vancomycin and over 20 other medications. These integrations aim to optimize user experience, reduce pharmacy workload, minimize transcription errors, and facilitate seamless coordination of care.

Products by PrecisePK

1 product in the directory

PrecisePK
PrecisePK
Clinical Decision Support & Reference
PrecisePK is a leading Bayesian Therapeutic Drug Monitoring (TDM) software that uses AI and advanced algorithms to provide precise drug dosing regimens and predict drug levels for various patient populations, aiding clinicians and pharmacists in optimizing patient care.

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Press & Coverage

PrecisePK
PrecisePK Partners with Pacific University Oregon to Advance Precision Medicine Research
PrecisePK announced a strategic collaboration with Pacific University Oregon to advance precision medicine research and innovation, aiming to optimize drug dosing strategies and improve therapeutic outcomes.
2024-04
PrecisePK
PrecisePK Introduces Groundbreaking Drug Models for Bayesian Precision Dosing
PrecisePK launched three new drug models for Bayesian precision dosing: Methotrexate, Cyclosporine, and Infliximab, to revolutionize therapeutic drug monitoring and forecasting for patients undergoing transplantation, immunosuppressive therapy, and oncology care.
2024-04
BioSpace
PrecisePK Redefines Precision Dosing with Academic Integration, Setting New Standards In Therapeutic Drug Monitoring
PrecisePK announced its integration into key healthcare and educational institutions in South America, earning recognition for its Bayesian dosing capabilities and aiming to transform patient care through tailored, data-driven dosing strategies.
2023-11
PR Newswire
PrecisePK Pioneers Model-Informed Precision Dosing and Pharmacokinetics Advancements in Argentina with Maza University
PrecisePK partnered with Maza University in Argentina, making it the first institution in the country to acquire their pharmacokinetics software, a significant step in advancing pharmacology education and clinical practice.
2023-12
PR Newswire
PrecisePK's Bayesian Precision Dosing Solutions Gain Trust of Premier Health System- Setting the Gold Standard for Clinicians in South America
PrecisePK announced a partnership with Clu00ednica Andes Salud Concepciu00f3n in Chile, solidifying its position as a leading Bayesian-based Therapeutic Drug Monitoring (TDM) solution in South America and aiming to elevate clinical outcomes and patient experiences.
2023-10
PR Newswire
PrecisePK Expands Its Global Standing as The Most Trusted Bayesian Dosing Software for South Korea's Health Systems
PrecisePK's technology is being implemented in several of South Korea's largest health systems, securing a 3-year contract with institutions like Chung-Ang University Healthcare System and Asan Medical Center.
2023-03
PrecisePK
PrecisePK Celebrates 30 Years of Bayesian Precision Dosing Partnership With UC San Diego Health
PrecisePK marked the 30th anniversary of its partnership with UC San Diego Health, highlighting the success of Bayesian precision dosing in improving patient outcomes and enhancing safety in oncology treatments.
2023-08
PrecisePK
PrecisePK Uses A.I. and Bayesian Dosing to Bridge the Gap between Research and Clinical Care
A paper published in Pharmacotherapy showed PrecisePK to be highly accurate in predicting Vancomycin AUC in critically ill patients, demonstrating its ability to bridge the gap between medical literature and bedside patient care using AI and Bayesian algorithms.
2020-10

Frequently Asked Questions

PrecisePK is a web-based platform that utilizes Bayesian analytics for Therapeutic Drug Monitoring (TDM) and Model-Informed Precision Dosing (MIPD). It individualizes dosing recommendations by adjusting population pharmacokinetic (PK) parameters with patient-specific data and serum levels, leading to more accurate and less biased drug exposure estimations. [1, 3, 6, 25]
PrecisePK offers Bayesian dosing models for over 20 medications across various therapeutic areas. This includes Vancomycin for infectious diseases, Methotrexate for oncology, and Cyclosporine and Infliximab for transplantation and autoimmune conditions, among others in cardiology and neurology. [1, 2, 7, 9, 11, 14, 17, 20, 21, 24]
PrecisePK provides real-time analytics and an AKI Predictor tool to assess a patient's risk of developing acute kidney injury, particularly in relation to vancomycin dosing. This feature helps clinicians proactively manage potential nephrotoxicity and optimize drug therapy. [1, 6, 10, 12, 15, 19, 21, 23]
PrecisePK is committed to high data security and compliance standards, holding SOC2 Type 2, ISO/IEC 27001:2022 (formerly 2013), HIPAA, and GDPR certifications. These ensure robust methodologies for information security management and protection of patient health information. [5, 6, 13]
PrecisePK offers customer support and actively seeks partnerships within the healthcare industry, including collaborations for product development, sales, and marketing. They have established integrations with platforms like Wolters Kluwer's Sentri7 Pharmacy and Sanford Guide, and partner with academic institutions for research. [8, 10, 11, 12, 15, 21, 24]
PrecisePK has a long-standing history in the industry, originating as T.D.M.S. 2000 in 1986 at UC San Diego Medical Center and Rady Children's Hospital. Rebranded in 2015 and launched as a web-based platform in 2019, it boasts over 30 years of clinical use in numerous hospitals globally. [3, 6, 7, 8, 13, 21, 24]
While specific pricing details are not publicly disclosed, PrecisePK's software is generally offered to healthcare institutions, likely on a subscription basis. The company does provide options for evaluation, including a free trial. [10, 14]

Investors

Who's funded PrecisePK.

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