About eko.ai Pte. Ltd. d/b/a Us2.ai

Us2.ai, formerly known as eko.ai Pte. Ltd., is a Singapore-based medtech company specializing in AI-powered solutions for echocardiography analysis. The company’s core offering is a machine learning platform that automates the often slow and manual process of analyzing echocardiograms. This technology aims to provide healthcare providers worldwide with faster, more accurate, and expert-level cardiac diagnostics, ultimately democratizing access to crucial heart health assessments.

For physicians, Us2.ai’s platform, including its flagship product Echo Copilot, offers fully automated analysis of echocardiographic studies, encompassing both 2D and Doppler images from various vendors. The software processes these images in minutes, generating comprehensive echo reports that include measurements, disease detection, and clinical findings for every heart chamber. This automation significantly reduces the manual workload for sonographers and cardiologists, allowing them to focus on critical thinking and patient care. The platform is FDA-cleared and CE-marked, with regulatory approvals in over 28 countries, and integrates seamlessly into existing clinical workflows, PACS, CVIS, and reporting systems.

The Us2.ai algorithm is designed to detect a wide array of heart-related conditions, such as heart failure (including HFrEF, HFmrEF, and HFpEF), cardiac amyloidosis, aortic stenosis, and pulmonary hypertension, aligning with international guidelines. It provides automated measurements for chamber dimensions, systolic and diastolic function, global and regional strain, and aortic stenosis metrics. The company’s mission is to improve patient outcomes and expand healthcare access by making high-quality, consistent, and affordable echo analysis available globally, addressing challenges like sonographer shortages and the complexity of echo interpretation.

Focus Areas

Echocardiography analysis AI in ultrasound imaging heart disease detection cardiovascular care cardiac amyloidosis heart failure pulmonary hypertension aortic stenosis strain imaging

Business Intelligence

TechnologyDeep learning solutions, AI-powered, cloud-native, integrates with ultrasound devices and PACS, automated pattern recognition, guideline-based measurements, DICOM processing, real-time analysis

What Physicians Need to Know

Echocardiography Analysis
Us2.ai offers 100% automated echocardiogram analysis, providing over 45 measurements including ejection fraction and strain for left atrium and right ventricle, without the need for ECG. The software analyzes transthoracic 2D and Doppler modality echocardiogram images, generating a complete patient report with editable annotations and findings based on international guidelines. This automation significantly reduces measurement and report creation time by 70%.
AI in Ultrasound Imaging
The company utilizes deep learning solutions for ultrasound medical imaging biomarkers, aiming to automate the fight against heart disease. Their AI platform fully automates expert-level echo analysis, producing results in under two minutes with no manual input and 100% reproducibility.
Heart Disease Detection
Us2.ai can detect a wide array of heart conditions, including heart failure (HFrEF, HFmrEF, HFpEF), cardiac amyloidosis, aortic stenosis, pulmonary hypertension, and valvular disease. For cardiac amyloidosis, it's the first platform to combine deep learning pattern recognition with guideline-based echocardiographic measurements for automated detection.
Cardiovascular Care
The technology aims to improve patient outcomes and expand healthcare access by democratizing echocardiograms. It provides clinical decision support by analyzing echocardiogram images to generate AI-derived measurements and functional reporting with disease indications in line with ASE & ESC guidelines.
Strain Imaging
The platform offers comprehensive analysis covering strain and regional strain imaging, including global longitudinal strain (GLS).
Physician Tip

Us2.ai's fully automated echocardiogram analysis can significantly reduce reporting time and measurement variability, allowing physicians to focus on critical thinking and patient care. The vendor-neutral and DICOM-native nature of the platform ensures seamless integration into existing workflows, regardless of ultrasound machine or PACS vendor. The AI-powered disease detection for conditions like cardiac amyloidosis and heart failure can aid in earlier diagnosis and improved clinical decision-making. Physicians retain final sign-off, as the system provides a pre-populated, fully editable draft report.

Us2.ai is vendor-neutral and DICOM-native, offering flexible integration pathways. It can be deployed bundled with ultrasound systems from OEM partners (e.g., Fujifilm, GE HealthCare, Canon Medical Systems), through AI marketplaces (e.g., Viz.ai), directly into cardiology PACS or reporting systems (supporting DICOM-SR, HL7, and PDF return), or via cloud and API for research and core-lab use. It integrates with any PACS, CVIS, or EMR via standard DICOM routing, with both cloud and on-premise deployment options. Partnerships include major players like Merge Cardio, allowing for seamless integration within existing cardiovascular imaging solutions.

Products by eko.ai Pte. Ltd. d/b/a Us2.ai

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What the Web Says

Us2.ai (eko.ai Pte. Ltd. d/b/a Us2.ai) is a healthcare AI company specializing in cardiology AI tools, particularly for echocardiogram analysis. Their platform aims to automate the full workflow of echo analysis, from DICOM input to structured report output, with the goal of improving efficiency, accuracy, and accessibility in cardiac care. The company has received positive feedback from cardiologists and sonographers regarding improvements in measurement accuracy and workflow efficiency. Us2.ai's products are FDA-cleared and available in over 28 markets.

Overall: Positive

Strengths

  • Fully automated echocardiogram analysis, including measurements, disease detection, and structured reports.
  • Significant time savings for technicians and cardiologists, reducing analysis and reporting time.
  • Enhances measurement accuracy and consistency, reducing variability between sonographers.
  • Addresses the shortage of cardiac sonographers and increasing demand for echo exams.
  • Reduces repetitive stress injuries for sonographers by minimizing manual measurements.
  • Vendor-neutral and integrates with existing PACS, CVIS, and EMR systems.

Limitations

  • No specific cons were identified in the provided search results.
  • No detailed employer reviews from Glassdoor or Capterra were found.
  • No specific product reviews from G2 or Capterra were found.
  • No Reddit discussions or reviews were found.

Based on reviews from: physicianaitools.com, deel.com, us2.ai, theimagingwire.com, indeed.com, fda.gov, fda.report, healthcareaiops.com, slashdot.org, parikhradiology.com

Last updated: 2026-10-29

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Press & Coverage

fda.gov
CDRH Premarket Authorizations that Used Real-World Evidence
Eko.ai Pte. Ltd. d/b/a Us2.ai utilized medical records data as a primary source of clinical evidence for the clearance of its 510(k) for a new device, involving a case-control study across the U.S. and Japan. This regulatory announcement highlights the use of real-world evidence in their FDA clearance process.
2026-06
healthcareaiops.com
FDA 510(k) K233676: Us2.v2 by Eko.Ai Pte Ltd. D/B/A Us2.Ai
Eko.Ai Pte Ltd. D/B/A Us2.Ai received FDA 510(k) clearance for its Us2.v2 device on April 1, 2024, under the AI-associated product code QIH. This clearance is a significant regulatory milestone for the company's AI-powered cardiology tools.
2026-08
fda.gov
510(k) Premarket Notification K250151 - Us2.ca
Eko.ai Pte. Ltd. d/b/a Us2.ai received 510(k) clearance for its Us2.ca device on June 20, 2025, which processes transthoracic cardiac ultrasound images to support the diagnosis of cardiac amyloidosis in adult patients. The device is an enhancement to their existing Us2.v2 software, adding the capability to detect cardiac amyloidosis.
2025-06
fda.gov
510(k) Premarket Notification K210791 - Us2.v1
Eko.ai Pte. Ltd. d/b/a Us2.ai received FDA 510(k) clearance for its Us2.v1 device on July 27, 2021, which is an image processing software utilizing machine learning algorithms to automate measurements of transthoracic cardiac images. The device has a safety and effectiveness profile similar to the predicate EchoMD Automated Ejection Fraction Software device.
2021-07
innolitics.com
Cardiology AI/ML 510(k) Submission
Eko.ai Pte. Ltd. d/b/a Us2.ai's Us2.v1 device received K210791 clearance in 2021, contributing to the increasing volume of Cardiology AI/ML clearances. This article discusses the trends and growth in FDA clearances for AI/ML in cardiology.
2026-01
physicianaitools.com
Healthcare AI in Singapore
Us2.ai, formerly known as Eko.ai, is a Singapore-based healthcare AI company focused on transforming cardiovascular diagnostics through advanced AI solutions. They are listed among other healthcare AI companies headquartered in Singapore.
2026-07
physicianaitools.com
Eko.Ai Pte Ltd. D/B/A Us2.Ai: healthcare AI company building cardiology ai tools for physicians
Eko.Ai Pte Ltd. D/B/A Us2.Ai is a healthcare AI company that develops cardiology AI tools for physicians, with information available on their products, pricing, compliance, and physician reviews. The company supports cardiovascular research for clinical applications.
2026-07
orthogonal.io
SaMD Cleared by the FDA: The Ultimate Running List
Eko.Ai Pte. Ltd. D/B/A Us2.Ai is included in a comprehensive list of FDA-cleared Software as a Medical Devices (SaMD), with their Us2.V1 device cleared on July 27, 2021. This list compiles publicly available data on SaMDs cleared by the FDA.
2024-10

Frequently Asked Questions

Us2.ai's platform can detect a wide range of heart-related conditions, including heart failure (HFrEF, HFmrEF, and HFpEF), cardiac amyloidosis, aortic stenosis, pulmonary hypertension, and valvular disease. It utilizes AI pattern recognition combined with guideline-based measurements to provide comprehensive disease screening and assessment.
Us2.ai's technology is backed by extensive clinical evidence, including peer-reviewed studies and validation against expert readers across multiple international cohorts. For instance, its automated systolic and diastolic function analysis has been validated in 'The Lancet Digital Health' to be as accurate as expert sonographers with less variability. The platform also provides fully explainable AI outcomes, allowing clinicians to directly edit annotations and trace results, ensuring transparency and physician oversight.
Us2.ai is FDA-cleared and CE-marked, holding regulatory approvals in over 28 markets worldwide, including the United States, European Union, Canada, and Australia. The company also maintains certifications such as HIPAA and GDPR compliance, ISO 27001:2022, SOC 2 Type II, and MDSAP, ensuring data security and privacy for enterprise healthcare deployments.
Us2.ai is designed for seamless integration with existing echo devices, PACS, CVIS, and EMR systems through standard DICOM routing. It offers both cloud and on-premise deployment options, with cloud deployment requiring no on-site hardware. For on-premise deployment, minimum hardware requirements include a 16-core CPU, 64 GB RAM, 12 GB VRAM GPU, and 1 TB SSD storage.
Us2.ai has established partnerships with various entities, including imaging OEMs like Fujifilm, AI platforms such as deepc and Viz.ai, and PACS systems like Merative Merge. These collaborations aim to integrate Us2.ai's AI capabilities into broader healthcare ecosystems, enhancing diagnostic workflows, expanding access to AI-driven echocardiography, and supporting initiatives like early detection pathways for conditions such as ATTR-CM.
While specific pricing models are not publicly detailed, Us2.ai aims to make echocardiogram analysis accessible and inexpensive through its automated technology. The company offers resources for evaluating AI echo, business case kits, and ROI calculators, suggesting a focus on demonstrating value. For support, Us2.ai provides comprehensive documentation and a trust center for security and compliance inquiries.
Us2.ai's mission is to democratize expert-level cardiac diagnostics globally by making echocardiography analysis faster, more accurate, and accessible. The company was founded in 2017 as eko.ai, secured significant funding rounds, and has achieved multiple FDA clearances and CE marks, indicating a strong growth trajectory and commitment to innovation in cardiovascular AI. Their continuous development and strategic partnerships further suggest a stable and forward-looking presence in the AI healthcare landscape.

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