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Us2.ca
Eko.Ai Pte Ltd. D/B/A Us2.Ai
Cardiology AI
Us2.ai is an FDA-cleared and CE-marked AI platform that fully automates echocardiography analysis, delivering comprehensive, structured cardiac reports in seconds to enhance diagnostic accuracy and workflow efficiency.

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About Eko.Ai Pte Ltd. D/B/A Us2.Ai

Us2.ai, formerly known as Eko.ai, is a Singapore-based healthcare AI company dedicated to transforming cardiovascular diagnostics through advanced machine learning. The company’s core offering is a platform that automates the analysis of echocardiograms, which are ultrasound images of the heart. This technology processes both 2D and Doppler views to generate comprehensive, structured echo reports, including measurements, disease detection, and clinical findings, often in a matter of minutes and with minimal to zero manual intervention.

For physicians, Us2.ai’s solutions, such as Us2.v1, Us2.v2, and Echo Copilot, are designed to significantly enhance workflow efficiency, improve diagnostic accuracy, and reduce inter-operator variability in echocardiogram interpretation. The platform is FDA-cleared and CE Marked, with clinical validation demonstrating its ability to provide expert-level analysis. By automating the traditionally time-consuming and labor-intensive process of echocardiography analysis, Us2.ai aims to democratize access to high-quality cardiac diagnostics globally, supporting the timely detection and management of various cardiovascular conditions, including heart failure, aortic stenosis, cardiac amyloidosis, pulmonary hypertension, and hypertrophic cardiomyopathy, and aiding in cardiovascular research and clinical trials.

Focus Areas

Echocardiography analysis AI-powered cardiac diagnostics heart failure cardiac amyloidosis aortic stenosis pulmonary hypertension strain imaging valvular disease real-time analysis automated reporting clinical trials EHR mining deep learning

Business Intelligence

Key InvestorsIHH Healthcare, Heal Partners, Sequoia India (now Peak XV Partners), EDBI, Pappas Capital, Partech Ventures, SGInnovate, Bfa Global Investors, East Post Road Ventures, FJ Labs
PartnershipsFujifilm, deepc, Harrison.ai, Merative Merge, Aidoc, Viz.ai, AstraZeneca, Janssen, Duke University, Brigham & Women's Hospital, Lenus Health
AcquisitionsNone
TechnologyDeep learning pattern recognition, AI-powered echocardiography analysis, cloud-native, integrates with ultrasound devices and PACS/CVIS/EMR, federated learning, zero-click automation, vendor-neutral
FDA Clearances3+ cleared products (estimated)

What Physicians Need to Know

Echocardiography Analysis
Fully automated, FDA-cleared, and CE-marked software for comprehensive echocardiogram analysis, processing 2D and Doppler images from any vendor. It provides automated estimation of cardiac structural and functional parameters, including left/right atrial and ventricular dimensions, volumes, systolic and diastolic function.
AI-Powered Cardiac Diagnostics
Leverages deep learning and advanced AI to automate the detection of a wide array of heart-related conditions, including heart failure (HFrEF, HFpEF, HFmrEF), cardiac amyloidosis, aortic stenosis, and pulmonary hypertension.
Disease-Specific Detection
Offers automated detection for cardiac amyloidosis (first and only platform to combine deep learning with guideline-based measurements), fully automated aortic stenosis severity grading, and complete right heart assessment for pulmonary hypertension.
Strain Imaging
Provides fully automated, vendor-agnostic Global Longitudinal Strain (GLS) from standard 2D echo, validated against leading vendor platforms, and regional strain analysis.
Real-time Analysis & Automated Reporting
Processes echocardiograms in real-time and delivers standardized, clinician-ready, structured reports automatically, including measurements, disease detection, and findings, often with zero clicks.
Clinical Trials & Research
Supports cardiovascular research for clinical trials, offering end-to-end echo analysis with automated workflow, QA, and audit logging. It also enables EHR mining for retrospective analysis to identify undetected disease.
Physician Tip

Us2.ai significantly streamlines your workflow by automating echocardiogram analysis and reporting, reducing interpretation time by up to 70% and minimizing inter-operator variability. This allows for faster diagnoses, increased patient throughput, and more time for direct patient care. The platform provides comprehensive, guideline-directed reports with editable AI outputs and transparent visual overlays, ensuring you maintain clinical oversight while benefiting from AI-driven insights. Its ability to detect conditions like cardiac amyloidosis automatically can aid in earlier diagnosis of often-missed diseases. Consider leveraging Us2.ai for standardizing echo reporting across your institution and for supporting clinical research initiatives.

Us2.ai is designed for flexible integration, being vendor-agnostic and compatible with all echo devices and PACS manufacturers. It connects to ultrasound devices and PACS, processing DICOM images, and can deliver results and reports via browser and/or send them to PACS or EMR systems. Deployment options include secure region-specific AWS cloud servers or on-premise solutions. The system operates as an additive layer, meaning your existing workflow continues unaffected even if the service is unavailable, and pilots can be run in parallel processing mode without production risk. Partnerships with platforms like Aidoc's aiOS and integration with ultrasound devices like Fujifilm's LISENDO 880 further enhance its integration capabilities.

Products by Eko.Ai Pte Ltd. D/B/A Us2.Ai

1 product in the directory

Us2.ca
Eko.Ai Pte Ltd. D/B/A Us2.Ai
Cardiology AI
Us2.ai is an FDA-cleared and CE-marked AI platform that fully automates echocardiography analysis, delivering comprehensive, structured cardiac reports in seconds to enhance diagnostic accuracy and workflow efficiency.

What the Web Says

Us2.ai (formerly Eko.ai Pte Ltd.) is a Singapore-based healthcare AI company that provides FDA-cleared, AI-powered echocardiography analysis software. The software aims to automate measurements, enhance accuracy, and improve workflow efficiency for cardiologists and sonographers. Reviews indicate positive perceptions from clinicians who have piloted the solution, noting improvements in measurement accuracy and faster reporting times.

Overall: Positive

Strengths

  • Enhances measurement accuracy and consistency.
  • Improves workflow efficiency and reduces reporting time significantly (e.g., 70% faster reporting, structured report in seconds).
  • Reduces manual work and sonographer fatigue, allowing more focus on patients.
  • Vendor-neutral, operating on standard DICOM across major ultrasound platforms and handheld POCUS devices.
  • FDA 510(k) cleared and CE Marked, with multiple peer-reviewed publications validating its technology.
  • Seamless integration into existing clinical workflows and systems like Merge Cardio.

Limitations

  • Initial technical challenges with integration into existing systems (though this has been resolved with Merge).
  • Some sonographers initially expressed concerns about AI replacing their roles (though this is framed as a misconception).
  • Poor image capture can lead to inaccurate annotations and measurements.
  • Requires careful review and adjustment by clinicians, as the software complements, but does not replace, clinical decision-making.
  • Limited information available on G2, Glassdoor, Capterra, or Reddit specifically for Us2.ai as an employer or product beyond healthcare IT reviews.

Based on reviews from: Us2.ai (User Perceptions of AI Echo), Us2.ai (How to Evaluate AI Echocardiography Platforms), Us2.ai (AI Echocardiography Reporting Software, FDA-Cleared), Merative (Integrating AI into cardiology imaging and reporting workflows for enhanced echo measurements), accessdata.fda.gov (Eko.ai Pte. Ltd. d/b/a Us2.ai K210791), Us2.ai (Clinical Evidence & Peer-Reviewed Publications), Radiology AI Tools Directory (Search FDA-cleared listings), accessdata.fda.gov (Eko.ai Pte. Ltd d/b/a Us2.ai K232835), accessdata.fda.gov (Eko.ai Pte. Ltd. d/b/a Us2.ai K250151), accessdata.fda.gov (TPLC - Total Product Life Cycle), Physician Ai Tools (DrFirst (Myndshft)), FDA (CDRH Premarket Authorizations that Used Real-World Evidence), Us2.ai (How Us2.ai and Merge Are Bringing AI Echo Directly Into Clinical Workflows), Us2.ai (AI Echo in Clinical Workflow), Indeed.com (Working at A.I: Employee Reviews)

Last updated: 2026-07-18

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Press & Coverage

Us2.ai
Canon Medical Systems USA and Us2.ai Announce Reseller Relationship for AI-Enabled Echocardiography
Canon Medical Systems USA and Us2.ai have partnered, allowing Canon to offer Us2.ai's cloud-based AI echocardiography software with its Aplio i-series ultrasound systems. This collaboration aims to integrate AI directly into clinical workflows, enhancing efficiency and patient care.
2026-07
Us2.ai
How Us2.ai and Merge Are Bringing AI Echo Directly Into Clinical Workflows
Us2.ai and Merge have integrated Us2.ai's AI directly into the Merge platform, eliminating the need for separate logins and streamlining workflows for echo technicians and cardiologists. This partnership aims to improve efficiency and patient care by embedding AI insights into existing clinical processes.
2026-04
Us2.ai
Us2.ai receives FDA clearance for Us2.v2, transforming cardiovascular ultrasound analysis
Us2.ai announced FDA clearance for Us2.v2, which includes 45 automated echo parameters and strain analysis, marking a significant advancement in cardiovascular ultrasound analysis. This clearance reinforces their commitment to improving cardiovascular care through innovative technology.
2024-04
Us2.ai
Us2.ai Secures US$15M Series A To Improve AI Detection of Cardiovascular Disease
Us2.ai raised $15 million in a Series A funding round to accelerate the global commercial and regulatory rollout of its automated echocardiography report software. The funds will drive growth targets for clinical implementation in the U.S., Europe, and Asia, and expand commercial activities with pharmaceutical companies, research labs, and imaging providers worldwide.
2022-04
PMC - NIH
Transforming echocardiography with artificial intelligence
This article discusses the integration of Us2.ai's CE-marked, vendor-neutral software platform for automated analysis of transthoracic echocardiograms (TTEs) at Erasmus Medical Center Rotterdam and Wilhelmina Ziekenhuis Assen. The implementation aims to improve efficiency, scalability, and consistency of echocardiographic services, with AI reducing analysis time by over 70%.
2025-09
Fujifilm Healthcare Americas Corporation
Fujifilm Partners with Us2.ai to Provide AI-Automated Echocardiography Analysis for Cardiologists and Sonographers Across the Nation
Fujifilm Healthcare Americas Corporation has partnered with Us2.ai to integrate Us2.ai's AI-driven, automated clinical workflow solution with Fujifilm's LISENDO 800 cardiovascular ultrasound system. This collaboration aims to provide fully automated analysis and reporting of echocardiograms, reducing measurement and report creation time by 70%.
2025-03
Us2.ai
Us2.ai receives CE mark for the latest version of its AI echo software
Us2.ai's latest version of fully automated echocardiography software has received CE Mark clearance, expanding its clinical deployment across Europe. The updated platform includes 68 CE-marked echo parameters and incorporates AI-based pattern recognition to detect cardiac amyloidosis.
2025-06
Us2.ai
Detection of Cardiac Amyloidosis with Us2.ai u2013Now FDA cleared and CE marked
Us2.ai's AI Echo Copilotu2122 software now includes a feature to assist in the detection of cardiac amyloidosis, having received FDA clearance in the United States and CE mark in Europe. This capability combines deep learning pattern recognition with guideline-based echocardiographic measurements for automated detection.
2025-06

Frequently Asked Questions

Us2.ai provides fully automated echocardiography analysis, featuring over 45 parameters and strain analysis, for conditions such as heart failure (HFpEF, HFmrEF, HFrEF), cardiac amyloidosis, aortic stenosis, and pulmonary hypertension. The platform offers real-time processing, delivering complete structured reports in seconds with zero manual clicks, significantly streamlining the diagnostic workflow.
Us2.ai's technology is extensively validated, backed by over 55 peer-reviewed publications in leading journals like The Lancet Digital Health, Nature Communications, JACC, and Circulation, across global multi-center studies. These studies demonstrate that its fully automated AI analysis significantly improves efficiency, reduces analysis time by up to 70%, and maintains accuracy comparable to expert human interpretation, thereby addressing deep learning concerns through robust evidence.
Us2.ai holds FDA 510(k) clearance for both Us2.v1 and Us2.v2, as well as CE Mark (Class IIb) in Europe, ensuring adherence to stringent regulatory standards. The platform is designed for seamless integration with various healthcare IT systems, including ultrasound devices, PACS, CVIS, and EMRs, offering flexible deployment options such as cloud or on-premise.
Us2.ai is a pioneer in combining deep learning pattern recognition with guideline-based echocardiographic measurements for the automated detection of cardiac amyloidosis. Its FDA-cleared algorithm analyzes a standard apical four-chamber view to identify subtle structural and functional patterns indicative of cardiac amyloid infiltration, facilitating earlier diagnosis of this often underdiagnosed condition.
Us2.ai significantly enhances workflow efficiency by providing fully automated, zero-click analysis and reporting, which can reduce measurement and report creation time by up to 70%. This automation helps increase daily scan volume, reduces mental and physical fatigue for sonographers, and allows clinicians to dedicate more time to patient interaction and complex care.
Us2.ai generally offers a volume-based pricing model, with installation and associated costs varying based on the specific configuration and integration requirements. While detailed support and training specifics are best obtained directly, the company emphasizes seamless integration and aims to provide solutions that clinicians can readily use, implying comprehensive support for deployment and ongoing operational assistance.
Us2.ai is a well-backed MedTech firm, supported by prominent investors including IHH Healthcare, Heal Partners, Peak XV Partners (formerly Sequoia India), and EDBI, having raised over $20.8 million in funding. They have established strategic partnerships with key industry players such as Fujifilm, Merative (Merge Cardio), deepc, and Viz.ai, demonstrating strong collaborations aimed at expanding market reach and enhancing integration capabilities.

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