Us2.ca

by Eko.Ai Pte Ltd. D/B/A Us2.Ai  · Based in Singapore →Your AI Echo Copilot™
Cardiology Radiology

Contact for pricing
Regulatory Status Disclosed

Overview

Us2.ai is an FDA-cleared and CE-marked artificial intelligence platform that fully automates echocardiography analysis, transforming cardiac diagnostics. It connects to ultrasound devices and PACS, processing echocardiograms in real time to deliver standardized, clinician-ready reports in seconds, not minutes. Unlike semi-automated tools, Us2.ai provides a complete structured report, including measurements, disease detection, and findings, often with zero clicks.

The platform is designed to improve workflow efficiency, reduce reporting time by up to 70%, and enhance diagnostic accuracy, addressing challenges like sonographer shortages and increasing clinical demands. Us2.ai’s AI-powered software automatically analyzes all heart chambers using both 2D and Doppler views, providing automated estimations of various cardiac structural and functional parameters. It incorporates deep learning pattern recognition with guideline-based echocardiographic measurements for automated detection of conditions such as cardiac amyloidosis, heart failure (HFpEF/HFrEF), pulmonary hypertension, and aortic stenosis.

Us2.ai supports clinical decision-making by providing fully explainable AI outcomes with transparent visual overlays and editable annotations directly from reports. The system integrates seamlessly with existing echo devices, CVIS, EMR, and PACS, offering both cloud and on-premise deployment options to ensure data security and compatibility with various infrastructures. Its technology is validated by peer-reviewed evidence and is used globally to democratize expert-level cardiac diagnostics, making high-quality, consistent, and inexpensive echo analysis accessible to healthcare providers worldwide.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Fully automated echocardiography analysis (zero clicks)
  • Real-time processing and structured report generation
  • AI-powered disease detection (e.g., Cardiac Amyloidosis, Heart Failure, Aortic Stenosis, Pulmonary Hypertension)
  • Integration with ultrasound devices, PACS, CVIS, and EMR
  • Guideline-based measurements and disease indication conclusions
  • Explainable AI with editable annotations and visual overlays
  • Comprehensive cardiac structural and functional parameters (2D, Doppler, M-mode, strain imaging)
  • Cloud and on-premise deployment options
  • Enterprise-grade security and compliance (ISO 27001:2022, MDSAP)
  • Vendor-neutral platform

Use Cases

  • Accelerating cardiac diagnosis and reporting
  • Improving workflow efficiency in echo labs
  • Standardized echo reporting for clinical trials and research
  • Population-level disease screening and retrospective analysis (EHR mining)
  • Supporting remote cardiovascular care and resource-limited settings
  • Enhancing clinical decision-making for cardiologists and sonographers

What Physicians Need to Know

Echocardiography AI Features
Us2.ai offers fully automated, zero-click echocardiography analysis, generating comprehensive structured reports with over 150 measurements, disease detection, and clinical findings in seconds. It automates parameters like LVEF, GLS, diastolic function, and structural assessments. The platform supports the detection of various heart conditions including heart failure (HFrEF, HFmrEF, HFpEF), cardiac amyloidosis, aortic stenosis, and pulmonary hypertension.
Cardiac Amyloidosis Detection
Us2.ai is the first and only platform to combine deep learning pattern recognition with guideline-based echocardiographic measurements for automated detection of cardiac amyloidosis. It is FDA cleared and CE marked for this specific detection, with studies showing over 90% accuracy.
Heart Failure Risk Prediction
The platform automates the heart failure echo workup, providing all parameters recommended in international guidelines (LVEF, GLS, diastolic function, etc.). It can classify heart failure subtypes (HFrEF, HFmrEF, HFpEF) and has demonstrated high sensitivity (100%) and specificity (94%) for AI-assisted detection and classification of heart failure from electronic health records. It also supports early diagnosis of heart failure using AI-powered handheld echocardiography.
AHA/ACC Guideline Alignment
Us2.ai provides guideline-directed, structured reporting with editable AI outputs and integrates international guidelines for comprehensive heart chamber analysis and disease indication conclusions. For hypertrophic cardiomyopathy (HCM), it utilizes a 30 mmHg or more cutoff for gradients, aligning with AHA/ACC 2024 guidelines.
Real-Time Alert Capability
Us2.ai processes echocardiograms in real-time, delivering results and disease detection in seconds, often before the patient leaves the exam room. It also offers real-time image guidance for novice operators using handheld echo devices.
Cardiac Monitoring Integration
The platform connects to ultrasound devices and Picture Archiving and Communication Systems (PACS), processing echocardiograms in real-time. It integrates with existing echo devices via Us2.connect and offers enterprise-wide storage options with PACS, CVIS, and EMR compatibility. Partnerships with Merge Cardio and deepcOSu00ae further enhance integration with imaging systems and AI platforms.
Physician Tip

Us2.ai significantly streamlines echocardiography analysis, reducing reporting time and improving consistency. Physicians can leverage its fully automated, zero-click reports for faster diagnoses and treatment decisions, especially for conditions like cardiac amyloidosis and heart failure. The guideline-aligned outputs and editable annotations ensure clinical control and transparency. Its ability to reanalyze archived studies can help uncover previously undetected diseases, aiding in population-level screening and longitudinal patient tracking. For busy echo labs, it can increase throughput and standardize reporting across institutions.

Us2.ai is designed for seamless integration with existing clinical infrastructure. It connects directly to ultrasound devices, PACS, CVIS, and EMR systems, with deployment options for both cloud and on-premise environments. Key partnerships, such as with Fujifilm (LISENDO 880 ultrasound system), Merative Merge (Merge Cardio), and Aidoc (aiOSu2122), demonstrate its capability to integrate with leading imaging systems and AI platforms, enhancing workflows and expanding its utility within broader cardiac care solutions.

Details

Category Cardiology AI, Radiology & Imaging AI
Pricing Contact for pricing Not publicly disclosed
DeploymentCloud, On-premise
Compliance
BAA AvailableUnknown AI-estimated
HIPAA Compliant Yes AI-estimated
FDA Status Yes AI-estimated

Us2.ai is FDA 510(k) cleared (K250151) for automated echocardiography analysis, including the detection of cardiac amyloidosis. Us2.v1 received clearance in 2021, Us2.v2 in 2024, and cardiac amyloidosis detection in 2025.

Integrations
EHR Not specified
Specialties Cardiology, Radiology

What the Web Says

Us2.ai is an AI-driven echocardiography reporting software that automates the analysis of cardiac ultrasound images, providing comprehensive, guideline-based reports in seconds. It has received FDA clearance and CE Mark, and its automated measurements have been validated in numerous peer-reviewed studies against expert readers. The platform aims to improve workflow efficiency, reduce clinician workload, and enhance diagnostic accuracy, ultimately supporting better patient care and operational efficiency.

Overall: Positive

Strengths

  • Fully automated echocardiography analysis, generating structured reports in seconds.
  • Validated accuracy against expert readers in peer-reviewed studies for various cardiac parameters and disease detection.
  • Enhances workflow efficiency, reduces reporting time, and decreases clinician fatigue.
  • Improves diagnostic accuracy and consistency, especially for conditions like cardiac amyloidosis and aortic stenosis.
  • Seamless integration with existing infrastructure (ultrasound devices, PACS, CVIS, EMR) with cloud or on-premise deployment options.
  • Preserves clinical autonomy by allowing physicians and sonographers to review and adjust AI-generated measurements.

Limitations

  • Some initial concerns from sonographers about AI potentially replacing their roles, though this is addressed as a misconception.
  • One physician noted a past challenge with manual data entry of AI measurements into their EMR, though this was resolved by integration with Merge.
  • Limited public reviews on platforms like G2 and Capterra specifically for Us2.ai, making it harder to gauge broader user sentiment from these sources.

Based on reviews from: Us2.ai: AI Echocardiography Reporting Software, FDA-Cleared, User Perceptions of AI Echo | Us2.ai, Top 10 Us2.ai Alternatives & Competitors in 2026 - G2, Compare EchoPAC vs. Us2.ai in 2026 - Slashdot, AI in Echo: State-of-the-art Automated Measurement Techniques and Clinical Applications, How Us2.ai and Merge Are Bringing AI Echo Directly Into Clinical Workflows, Clinical Evidence & Peer-Reviewed Publications | Us2.ai, AI Echo in Clinical Workflow | Us2.ai, AI-driven tools into echocardiography practice : r/cardiacsonography - Reddit, Peer-Reviewed Study: Novice Users Acquire Diagnostic-Quality Cardiac Ultrasound Images With AI Guidance, Point-of-care AI-enhanced novice echocardiography for screening heart failure (PANES-HF), I tried a lot of AI medical scribes so you don't have to - my honest review : r/medicine - Reddit, Us+AI Reviews & Product Details - G2, 2024 Year in Review | Us2.ai, Capterra: Find The Right Software, AI proved superior in assessing and diagnosing cardiac function when compared with echocardiogram assessments made by sonographers : r/science - Reddit, I tried all the AI medical scribes so you don't have to - my honest review - Reddit, Capterra Reviews & Ratings 2026 - TrustRadius, Capterra Pros and Cons | User Likes & Dislikes - G2, G2 Reviews | Read Customer Service Reviews of www.g2.com - Trustpilot, Capterra Reviews 2026: Details, Pricing, & Features | G2, Top 8 Claude Skills for UI/UX Engineers - Snyk

Last updated: 2026-07-18

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Press & Coverage

Us2.ai
Canon Medical Systems USA and Us2.ai Announce Reseller Relationship for AI-Enabled Echocardiography
Canon Medical Systems USA and Us2.ai have partnered, allowing Canon to offer Us2.ai's cloud-based AI echocardiography software with its Aplio i-series ultrasound systems to automate measurements and reporting.
2026-07
Us2.ai
Med Q&A with Us2.ai's Co-Founder Dr. Carolyn Lam: The Future of AI-Enabled Cardiology
Dr. Carolyn Lam, co-founder of Us2.ai, discusses in Med (Cell Press) how AI can address the issue of access in cardiovascular care by providing a fully automated echocardiographic measurement and reporting workflow.
2026-07
Us2.ai (Circulation: Cardiovascular Imaging)
Integrating Clinical Data with AI Echocardiography for Improved Cardiac Amyloidosis Detection
This international multicenter study, published in Circulation: Cardiovascular Imaging, demonstrates that integrating clinical and laboratory data with the FDA-cleared Us2.Ca deep learning model significantly improves cardiac amyloidosis detection.
2026-06
Us2.ai (International Journal of Cardiology)
AI Echo for Post-AMI Risk Stratification: Predicting Outcomes After A Heart Attack
Published in the International Journal of Cardiology, this study shows that combining AI-derived echocardiographic parameters with traditional clinical risk factors significantly improves prediction of one-year mortality and major adverse cardiac events after a heart attack.
2026-06
FDA
Us2.ca FDA 510(k) Clearance for Cardiac Amyloidosis Detection
The FDA granted 510(k) clearance to Us2.ca for processing transthoracic cardiac ultrasound images to support qualified healthcare practitioners in diagnosing cardiac amyloidosis in adult patients with increased left ventricular wall thickness.
2025-06
Us2.ai
Us2.ai receives CE mark for the latest version of its AI echo software
Us2.ai announced that its latest version of fully automated echocardiography software has received CE Mark clearance, expanding its clinical deployment across Europe and offering comprehensive, guideline-directed echo analysis and cardiac amyloidosis detection from a single view.
2025-06
Us2.ai
Alnylam and Viz.ai Build ATTR-CM Early Detection Pathway with Us2.ai Echo AI
Us2.ai has been selected as the echocardiography AI algorithm for Alnylam and Viz.ai's strategic collaboration to build an AI-enabled ATTR-CM care pathway, aiming to identify patients earlier in the course of the disease.
2026-03
MedTech Innovator
Fujifilm strikes partnership with Us2.ai for AI echocardiography analysis
Fujifilm is collaborating with Us2.ai to integrate its AI-based image analysis software into Fujifilm's LISENDO 880 and LISENDO 800 cardiovascular ultrasound systems to expedite cardiology image analysis and provide disease indication conclusions.
2025-03

Videos

Product demos, reviews, and walkthroughs for Us2.ca.

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Frequently Asked Questions

Us2.ca seamlessly connects to your ultrasound devices and PACS, processing echocardiograms in real-time to deliver standardized, clinician-ready reports. It automates over 150 measurements, including chamber dimensions, systolic and diastolic function, and strain, significantly reducing manual analysis time and generating disease indications in line with guidelines.
Us2.ca is FDA-cleared and CE-marked, indicating it meets stringent regulatory standards for medical devices. While specific data privacy protocols like HIPAA or GDPR compliance are not detailed in the provided snippets, Us2.ai's solutions are designed to integrate securely into clinical workflows, implying adherence to relevant data protection regulations.
Us2.ca is primarily intended for adult patients with increased left ventricular wall thickness (IVSd or LVPWd u2265 12mm) to aid in the diagnosis of cardiac amyloidosis. It is not intended to provide a definitive diagnosis, replace current standards of care, or for the assessment of congenital heart disease, valve disease, pericardial disease, or intra-cardiac lesions.
In multi-center studies, Us2.ca achieved over 90% accuracy in detecting cardiac amyloidosis, with internal validation cohorts showing diagnostic accuracy of 95.8% to 96.2%. Peer-reviewed studies and clinical deployments demonstrate significant efficiency gains, including a 9% reduction in reporting time and ~10% faster diagnosis time.
Us2.ca offers fully automated analysis and reporting, unlike semi-automated tools that measure one parameter at a time, significantly reducing measurement and report creation time by up to 70% compared to manual methods. It provides comprehensive cardiac measurements and disease indications, aiming to improve consistency and expand access to expert-level cardiac imaging.
The pricing model for Us2.ai (which includes Us2.ca) is subscription-based, typically determined by the number of analyses performed. Potential cost-effectiveness benefits include reduced workload for medical staff, fewer errors, and faster diagnosis times, which can lead to improved patient outcomes and more efficient resource utilization.
While specific details on training programs are not extensively outlined, Us2.ai's solutions are designed to integrate seamlessly into clinical workflows, implying user-friendly interfaces. The platform aims to empower clinicians by providing guideline-directed, structured reporting with editable AI outputs for confident clinical decisions.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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