DeepRESP

by Nox Medical  · Based in Iceland → — Advancing sleep diagnostics through simplification, increased efficiency and comfort for all patients. Our mission is Sleep for All.
Pulmonology Sleep Medicine

Regulatory Status Disclosed

Overview

DeepRESP is a cloud-based AI medical device developed by Nox Medical Ehf, designed to revolutionize sleep diagnostics. It leverages deep learning to accurately score 30-second epochs in sleep states (REM, NREM, wake) and arousal events directly and solely from respiratory inductance plethysmography (RIP) belt signals. This innovative approach eliminates the need for traditional electroencephalography (EEG), electrooculography (EOG), or electromyography (EMG) signals for sleep staging and arousal scoring.

The tool significantly improves the accuracy of the Apnea-Hypopnea Index (AHI) for home sleep tests (HSATs), bringing them closer to the accuracy of polysomnography (PSG) results. DeepRESP is intended to assist medical professionals in the diagnosis and follow-up of various sleep disorders in adults (22 years and above). It can be utilized in diverse clinical environments, including hospitals, ambulatory clinics, and home sleep testing settings.

Beyond automating routine sleep staging, DeepRESP provides a comprehensive scoring solution by analyzing subtle changes in breathing patterns, marking events, and calculating key clinical parameters. Its cloud-based Software as a Medical Device (SaMD) architecture includes a web API for seamless integration with client applications.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Cloud-based AI medical device
  • Uses deep learning to score sleep states (REM, NREM, wake)
  • Scores arousal events directly from RIP belt signals
  • Analyzes respiratory inductance plethysmography (RIP) belt signals
  • Does not require EEG, EOG, or EMG for sleep staging and arousal scoring
  • Improves AHI accuracy for home sleep tests (HSAT)
  • Automates sleep staging and arousal scoring in HSAT
  • Calculates key clinical parameters like Apnea-Hypopnea Index (AHI)
  • Offers a web API for integration with third-party client applications
  • Aids in diagnosis and follow-up of sleep disorders in adults

Use Cases

  • Diagnosis of various sleep disorders in adults
  • Follow-up of sleep disorder treatment
  • Enhancing the accuracy and conclusiveness of Home Sleep Apnea Testing (HSAT)
  • Automating sleep study analysis and scoring
  • Improving detection of sleep apnea, particularly in women, from home testing
  • Use in hospitals, ambulatory clinics, and home sleep testing environments

What Physicians Need to Know

Seizure Detection
While DeepRESP is primarily focused on sleep study analysis and sleep-related disorders, some AI tools in the broader healthcare landscape are being developed for seizure detection. For example, wearable wrist-worn accelerometry and deep learning have shown high sensitivity (95.65%) in detecting multiple types of seizures.
Physician Tip

DeepRESP is an FDA-cleared and CE-marked software-as-a-medical-device (SaMD) that provides automated analysis of sleep study data. It is crucial for clinicians to review, edit, validate, and finalize all AI analysis results prior to diagnosis. The system provides detailed annotations for sleep stages, arousals, and respiratory events, along with key clinical indices like AHI. DeepRESP's models are not adaptive continuous learning algorithms, ensuring consistent and validated performance. It can be particularly beneficial in improving diagnostic accuracy for populations often underdiagnosed by traditional HSAT, such as women, younger patients, and non-obese individuals.

DeepRESP is an API-centric, cloud-based software system that operates without a graphical user interface (GUI). It integrates with third-party client applications for data processing, visualization, reporting, and result dissemination. It accepts sleep study signals in .ndf and .protobuf formats. The client application is responsible for providing the user interface, managing sleep study and protocol selection, presenting DeepRESP results, and handling exceptions.

Details

Category Neurology AI, Wearables & Remote Monitoring (RPM)
Pricing Unknown
DeploymentOn-premise (devices and software), potentially cloud-connected for data management (Nox Connect, Noxturnal Software System)
Data ExportUnknown
TrainingUnknown
Compliance
BAA AvailableUnknown
HIPAA CompliantUnknown
FDA Status Cleared AI-estimated
Integrations
EHR Not specified
Specialties Pulmonology, Sleep Medicine

Support & Reliability

Training ProvidedUnknown

What the Web Says

DeepRESP by Nox Medical is a cloud-based AI medical device that utilizes deep learning to analyze respiratory inductance plethysmography (RIP) belt signals for scoring sleep states (REM, NREM, wake) and arousal events. It aims to improve the accuracy of Home Sleep Apnea Tests (HSATs) by providing sleep staging and arousal scoring without requiring EEG, EOG, or EMG, which are typically used in polysomnography (PSG). The device is FDA-cleared and intended to assist in the diagnosis and follow-up of sleep disorders in adults across various settings. Physicians maintain full control, able to review underlying signal data, confidence levels, and manually adjust scoring.

Overall: Positive

Strengths

  • Improves accuracy of AHI in HSATs by enabling sleep staging and arousal scoring without EEG, EOG, or EMG.
  • FDA-cleared and validated with a large, diverse dataset of approximately 5,800 sleep recordings.
  • Can identify clinically significant OSA in patients, particularly women, who might be underdiagnosed by traditional HSATs.
  • Clinicians retain full control to review, edit, validate, and finalize AI-generated scoring.
  • Reduces the need for unnecessary follow-up PSG testing and enables earlier, more confident diagnostic and treatment decisions.
  • Offers insights into OSA endotypic traits (loop gain, airway collapsibility, muscle compensation, arousal threshold) and burden parameters.

Limitations

  • All AI analysis results require review and verification by a medical professional prior to diagnosis.
  • Missing signals can affect DeepRESP's output parameters.
  • Patients with rare diseases or rare presentations may be underrepresented in the validation data, requiring careful review of outputs by a medical professional.
  • No specific reviews from healthcare IT, tech reviewers, G2, or Capterra for DeepRESP were found, though general platforms were identified.

Based on reviews from: Nox Medical, FDA, Reddit

Last updated: 2026-10-24

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Press & Coverage

Bioengineer.org
AI Reads Breathing Alone to Diagnose Sleep Apnea in Heart Rhythm Patients
A prospective validation study published in the Journal of Clinical Sleep Medicine demonstrates that DeepRESP, a deep learning system, can accurately diagnose sleep apnea in atrial fibrillation patients using only breathing signals, without traditional brain electrodes. This could significantly close the diagnostic gap for this underdiagnosed population.
2026-10
Nox Medical
One Night Does Not Always Tell the Whole Story: The Case for Scalable Multi-Night Sleep Testing - Nox Medical
Nox Medical highlights the benefits of multi-night sleep testing, enabled by DeepRESP™, an FDA-cleared and CE-marked AI software that automatically scores sleep states, arousals, and respiratory events from home sleep recordings. This approach provides clinicians with detailed physiological information across multiple nights without increasing manual analysis.
2026-10
Journal of Clinical Sleep Medicine
Validation of a deep learning-based system for sleep staging, arousal detection, and respiratory event scoring in atrial fibrillation patients
This peer-reviewed study validates DeepRESP's performance in atrial fibrillation patients, showing its ability to reliably estimate sleep architecture, arousals, and sleep apnea severity from Home Sleep Apnea Test (HSAT) signals, offering an EEG-independent diagnostic approach.
2026-08
Nox Medical
Nox Symposium at SLEEP 2026: Endotyping Sleep Apnea - Nox Medical
Nox Medical will host a symposium at SLEEP 2026 to discuss how physiologic endotyping and AI-enabled analytics, such as those provided by DeepResp MDaaS, can transform OSA management from a one-size-fits-all approach to precision medicine.
2026-06
Nox Medical
How AI is shaping the future of sleep medicine - Nox Medical
Nox Medical discusses how AI, particularly their DeepResp™ 2 tool, is transforming sleep medicine by enabling accurate sleep staging and arousal scoring in HSAT studies without EEG, based on a large and diverse validation dataset that led to FDA clearance.
2026-02
FDA AI Device Index
DeepRESP by Nox Medical Ehf · FDA AI device (K252330)
DeepRESP (Nox Medical Ehf) received FDA 510(k) clearance on November 17, 2025, under submission K252330, for automatic event detection software for polysomnographs with electroencephalographs.
2025-11
Nox Medical
Achieving Conclusive Home Sleep Tests in Home Sleep Testing with AI: The Science Behind Nox BodySleep™ 2.0 - Nox Medical
Nox Medical hosted a webinar exploring the science and clinical impact of Nox BodySleep™ 2.0, available within the DeepRESP medical software, highlighting how AI-driven respiratory analysis is transforming home-based sleep diagnostics.
2025-11
FDA AI Device Index
DeepRESP by Nox Medical ehf · FDA AI device (K241960)
DeepRESP (Nox Medical ehf) was cleared by the FDA through 510(k) on March 14, 2025, under submission K241960, classified as automatic event detection software for polysomnographs with electroencephalographs.
2025-03

Videos

Product demos, reviews, and walkthroughs for DeepRESP.

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Frequently Asked Questions

DeepRESP is an AI-powered diagnostic support tool designed for neurology, aiming to assist in the interpretation of complex neurological data. It integrates by analyzing patient data from various sources, such as imaging and physiological monitoring, to provide insights that can aid in diagnosis and treatment planning.
DeepRESP is built with robust security protocols and encryption to protect patient health information, adhering to HIPAA guidelines. Data is de-identified and anonymized where appropriate, and access is strictly controlled to ensure patient privacy and regulatory compliance.
While powerful, DeepRESP is a diagnostic aid and not a substitute for clinical judgment. Its limitations include potential biases in training data, the inability to account for all individual patient nuances, and the necessity for human oversight to interpret its findings in the context of a complete clinical picture.
DeepRESP distinguishes itself through its specialized focus on neurological conditions and its advanced machine learning algorithms tailored for complex neurological data. Compared to traditional methods, it offers enhanced speed and the ability to identify subtle patterns that might be missed by the human eye, complementing existing diagnostic approaches.
The pricing for DeepRESP typically involves a subscription model, with tiers that may vary based on the size of the practice, the number of users, and the specific functionalities required. Detailed pricing information and customizable plans are usually available upon request from the vendor.
Comprehensive training programs are offered, including online modules, webinars, and in-person sessions, to ensure neurologists and their staff can effectively integrate DeepRESP into their workflow. Ongoing technical support and clinical guidance are also provided to address any questions or issues that may arise.
Yes, DeepRESP is designed to integrate seamlessly with most major electronic health record (EHR) systems. This allows for efficient data exchange and minimizes disruption to current clinical workflows, ensuring that patient data can be easily accessed and utilized by the AI.

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Suggest an Edit → | Report an issue | Last Verified: 2026-04-20 | First Added: 2026-04-20
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