Biograph Vision.X and Biograph Vision.X Edge

by Siemens Medical Solutions USA, Inc.  · Based in United States → — Redefine PET/CT imaging with the precision-driven performance.
Nuclear Medicine Oncology Radiology

Contact vendor for details.
Regulatory Status Disclosed

Overview

The Biograph Vision.X and Biograph Vision.X Edge, from Siemens Medical Solutions USA, Inc. (a Siemens Healthineers company), represent the next generation of Positron Emission Tomography/Computed Tomography (PET/CT) scanners. These systems build upon the established performance of the Biograph Vision family, delivering industry-leading technical specifications to transform accurate decision-making in clinical practice.

At its core, the Biograph Vision.X features Optiso Ultra Dynamic Range (UDR) detector technology, utilizing small 3.2-mm lutetium oxyorthosilicate (LSO) crystals that are 100% covered by Silicon Photomultipliers (SiPMs). This innovative design enables an ultrafast Time of Flight (TOF) performance of 178 picoseconds (ps), which is recognized as the industry’s fastest TOF, and delivers high 48-mm³ volumetric resolution. This technological advancement translates into a significant performance gain of up to 20%, leading to faster scans, reduced injected dose, and lower radiotracer costs, while enhancing patient comfort.

The scanner incorporates the built-in AIDAN intelligent imaging platform, which leverages artificial intelligence (AI) to boost operational efficiency and streamline patient workflow for more precise diagnoses. An optional feature, FlowMotion AI, combines continuous bed motion with anatomical AI to standardize and personalize image acquisitions with a single click. Designed with a large 78-cm bore, the system aims to reduce patient anxiety and facilitate easier positioning for bariatric patients or those requiring radiotherapy devices. Additionally, the Biograph Vision.X is available as an in-field upgrade for existing Biograph Vision users, allowing them to extend the performance of their current systems.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Industry's fastest Time of Flight (TOF) performance of 178 picoseconds (ps)
  • Optiso Ultra Dynamic Range (UDR) detector technology with 3.2-mm LSO crystals and 100% SiPM coverage
  • High 48-mmu00b3 volumetric resolution
  • Up to 20% performance improvement (TOF gain) for faster scans and lower dose
  • Built-in AIDAN intelligent imaging platform leveraging AI
  • FlowMotion AI (optional) for standardized and personalized image acquisitions
  • Large 78-cm bore for enhanced patient comfort and positioning
  • In-field upgradeability for existing Biograph Vision users
  • Reduced patient radiation exposure and radiotracer costs
  • Enhanced operational efficiency and accelerated patient workflow

Use Cases

  • Whole-body oncology examinations
  • Neurology examinations
  • Cardiology examinations
  • Improved lesion detection and anatomical detail
  • Therapy monitoring and post-therapy follow-up
  • Theranostics, particularly for recurrent prostate cancer

What Physicians Need to Know

Cardiac CT Analysis
The integrated CT component of the Biograph Vision.X and Vision.X Edge systems offers high spatial resolution and image quality, crucial for detailed cardiac anatomical assessment. The systems incorporate features like 'CardioFreeze' (optional) which corrects for respiratory motion in the heart, enhancing the clarity of cardiac CT images.
Cardiac PET Quantification
The systems provide high image resolution and sensitivity for precise quantification, delivering metrics such as standard uptake volume (SUV), metabolic glucose rate, and distribution volume. This quantitative imaging capability is vital for assessing myocardial viability and function, which are key in managing heart failure and understanding coronary physiology through myocardial blood flow (MBF) and myocardial flow reserve (MFR) calculations.
Coronary Artery Assessment
The Biograph Vision.X and Vision.X Edge are utilized for the delineation of multivessel coronary artery disease and post-therapy stent occlusion through 82Rb myocardial perfusion PET/CT and blood flow estimation. The high-resolution imaging supports non-invasive assessment of coronary artery morphology.
AI-Powered Workflow & Image Quality
The built-in AIDAN intelligent imaging platform leverages artificial intelligence (AI) to enhance operational efficiency and accelerate patient workflow. An optional 'FlowMotion AI' feature combines continuous bed motion with anatomical AI for standardized and personalized image acquisitions, contributing to more consistent and accurate results.
Cardiac Monitoring Integration
The 'CardioFreeze' feature integrates cardiac gating to correct for respiratory motion, which is essential for obtaining clear and accurate cardiac PET/CT images. This indicates integration with physiological monitoring for synchronized image acquisition.
Physician Tip

Leverage the advanced time-of-flight performance and high spatial resolution of Biograph Vision.X and Vision.X Edge for superior image quality, enabling more confident and precise diagnoses in complex cardiac conditions. Utilize the quantitative PET capabilities for comprehensive assessment of myocardial function and perfusion, which can be critical for heart failure management and treatment planning. Employ the AI-driven workflow enhancements, such as AIDAN and FlowMotion AI, to optimize scan protocols, reduce scan times, and minimize patient radiation exposure, thereby improving patient comfort and departmental throughput. Pay close attention to the motion correction features like CardioFreeze, especially for cardiac studies, to ensure artifact-free images for accurate interpretation of coronary anatomy and myocardial viability.

The Biograph Vision.X and Vision.X Edge systems feature the integrated AIDAN intelligent imaging platform for AI-driven workflow and image processing. They also support integration with cardiac gating systems for motion correction during cardiac imaging. The CT component can incorporate advanced subcomponents like those from the SOMATOM Definition series, suggesting a robust imaging chain. While not explicitly detailed, the system's output is designed to be utilized within broader clinical decision support systems, aligning with established medical guidelines for comprehensive patient care.

Details

Category Cardiology AI, Neurology AI, Oncology AI
Pricing Contact vendor for details. — Not publicly available.
DeploymentOn-premise (physical PET/CT scanner)
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Yes AI-estimated

The Biograph Vision.X and Biograph Vision.X Edge are combined X-Ray Computed Tomography (CT) and Positron Emission Tomography (PET) scanners cleared for whole-body oncology, neurology, and cardiology examinations.

Integrations
EHR Not specified
Specialties Nuclear Medicine, Oncology, Radiology

What the Web Says

The Siemens Biograph Vision.X and Biograph Vision.X Edge are advanced PET/CT scanners that build upon the established Biograph Vision platform, offering significant improvements in image resolution, sensitivity, and operational efficiency. They are designed to provide more precise diagnoses, particularly in oncology, neurology, and cardiology, by leveraging cutting-edge detector technology and artificial intelligence. The systems aim to enhance patient experience by reducing scan times and radiation exposure.

Overall: Positive

Strengths

  • Industry-leading time-of-flight (TOF) performance of 178 picoseconds, enabling faster scans and improved image quality.
  • High spatial and volumetric resolution due to small 3.2 mm x 3.2 mm LSO crystal elements and 100% SiPM coverage, leading to better detection of small lesions and anatomical detail.
  • Reduced patient radiation exposure and radiotracer cost due to improved performance and sensitivity.
  • Enhanced operational efficiency and accelerated patient workflow through the AIDAN intelligent imaging platform, which utilizes AI and machine learning.
  • Large 78-cm bore to reduce patient anxiety and facilitate positioning for bariatric or radiotherapy patients.
  • In-field upgradeability for existing Biograph Vision users.

Limitations

  • No specific cons were identified in the provided search results from physicians, healthcare IT, tech reviewers, Reddit, G2, or Capterra.
  • One Reddit comment suggests that a 70cm bore (referring to a different Siemens model, the Trinion) is a deal-breaker in this day and age, though the Vision.X has a 78cm bore.
  • The Biograph Vision.X was pending 510(k) clearance and not commercially available in the US or other countries at the time of some publications (June 2023), though it has since received FDA clearance (November 2023).

Based on reviews from: ICE Magazine, Cassling, Siemens Healthineers Debuts Biograph Vision.X PET/CT Scanner (June 29 2023), The Clu00ednic Barcelona debuts the Biograph Vision.X system, pioneering technology in diagnostic imaging in Europe, Siemens Healthineers Debuts Biograph Vision.X PET/CT Scanner (June 25 2023), Siemens Biograph PET/CT Scanners Compared | Block Imaging, FDA Clears New PET/CT Scanner from Siemens Healthineers | Diagnostic Imaging, Biograph Vision PET / CT System - Medical Device Network, Siemens PET/CT Comparison Chart | Radiology Oncology Systems, Biograph Vision PET/CT Systems - accessdata.fda.gov, Comparison of the Biograph Vision and Biograph mCT for quantitative 90Y PET/CT imaging for radioembolisation - PubMed, Biograph Vision PET/CT System from Siemens Healthineers at SNMMI 2018 - YouTube, (PDF) Performance Evaluation of the Time-of-Flight Biograph Vision.X: A Fast Coincidence Time Resolution PET/CT Scanner - ResearchGate, GE Omni vs Siemens Trinion : r/NuclearMedicine - Reddit, GE Discovery vs Siemens Biograph Vision 600 : r/Radiology - Reddit, Siemens Launches New PET/CT Scanner at SNMMI 2023 - Applied Radiology

Last updated: 2026-07-20

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Press & Coverage

FDA
Biograph Vision.X and Biograph Vision.X Edge 510(k) Premarket Notification
This regulatory announcement from the FDA details the 510(k) premarket notification for the Biograph Vision.X and Biograph Vision.X Edge PET/CT systems, indicating substantial equivalence to previously cleared devices.
2023-07
accessdata.fda.gov
Biograph Vision PET/CT Systems
This FDA document provides further details on the Biograph Vision.X and Biograph Vision.X Edge, including their classification, intended use for oncology, neurology, and cardiology examinations, and compliance with various standards.
2025-07
Medical AI Tools for Physicians
TruPlan vs Biograph Vision.X and Biograph Vision.X Edge
This article compares TruPlan, an AI-enabled software for Left Atrial Appendage Closure procedures, with Biograph Vision.X and Vision.X Edge, advanced PET/CT scanners utilizing AI for high-resolution imaging across oncology, neurology, and cardiology.
unknown
Physician Ai Tools
Reveal LINQ vs Biograph Vision.X and Biograph Vision.X Edge
This comparison highlights the differences between the Reveal LINQ implantable cardiac monitor and the Biograph Vision.X PET/CT scanner, emphasizing their distinct functionalities in continuous cardiac monitoring versus high-resolution diagnostic imaging.
unknown
Physician Ai Tools
Vivid Pioneer vs Biograph Vision.X and Biograph Vision.X Edge
This article contrasts GE HealthCare's Vivid Pioneer cardiovascular ultrasound system with Siemens' Biograph Vision.X and Vision.X Edge PET/CT scanners, noting their different imaging modalities and AI applications.
unknown
Physician Ai Tools
Revolution Vibe vs Biograph Vision.X and Biograph Vision.X Edge
This comparison examines the GE HealthCare Revolution Vibe, an AI-powered CT system for cardiac imaging, against the Siemens Biograph Vision.X and Vision.X Edge PET/CT scanners, which offer broader diagnostic capabilities.
unknown
Physician AI Tools
Tempus ECG-Low EF vs Biograph Vision.X and Biograph Vision.X Edge
This article compares Tempus ECG-Low EF, an AI software for early heart failure risk identification, with Biograph Vision.X and Edge PET/CT scanners, which provide precise metabolic and anatomical imaging across various medical fields.
unknown
Physician AI Tools
uMI Panvivo vs Biograph Vision.X and Biograph Vision.X Edge
This comparison analyzes the uMI Panvivo PET/CT system against the Biograph Vision.X and Vision.X Edge, highlighting their respective strengths in compact design and industry-leading Time of Flight performance for diagnostic imaging.
unknown

Videos

Product demos, reviews, and walkthroughs for Biograph Vision.X and Biograph Vision.X Edge.

View all on YouTube

Frequently Asked Questions

The Biograph Vision.X and Vision.X Edge systems incorporate the AIDAN intelligent imaging platform, which leverages artificial intelligence to improve operational efficiency and accelerate patient workflow. This AI, built on over 700 machine- and deep-learning patents, enhances image resolution, potentially allowing physicians to detect smaller lesions and provide more precise diagnoses.
The Biograph Vision.X and Vision.X Edge have received U.S. Food and Drug Administration (FDA) 510(k) clearance, indicating they are substantially equivalent to legally marketed predicate devices. Siemens Healthineers has also provided cybersecurity information in accordance with FDA Guidance documents, implementing specific controls to prevent unauthorized access or misuse of information.
The Biograph Vision.X and Vision.X Edge are noted for their industry-leading time of flight (TOF) performance of 178 picoseconds, which contributes to superior image resolution and a 20% performance improvement. Their AIDAN AI platform, including optional FlowMotion AI, is a key differentiator, offering automated standardization and personalization of image acquisitions.
While AI features aim to streamline workflow and enhance image quality, potential challenges could include the need for staff training on new AI-driven protocols and ensuring seamless integration with existing hospital IT infrastructure. Like any advanced technology, ongoing software updates and maintenance are also considerations for optimal performance.
Yes, the AI features, particularly the AIDAN platform and FlowMotion AI, are designed to increase operational efficiency and accelerate patient workflow by standardizing and personalizing image acquisitions. This can lead to reduced scan times, lower patient radiation exposure, and decreased radiotracer costs.
Specific pricing for medical capital equipment like the Biograph Vision.X and Vision.X Edge is typically not publicly disclosed and varies based on configuration, regional market, and negotiated contracts. However, these systems represent a significant investment in cutting-edge technology, and AI-specific features may be included in the overall system cost or offered as optional upgrades.
Siemens Healthineers has implemented specific cybersecurity controls within the Biograph Vision.X and Vision.X Edge software to prevent unauthorized access, modification, misuse, or denial of use of patient data. These controls also protect information stored, accessed, or transferred between the systems and external devices, adhering to FDA guidance documents.

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Suggest an Edit → | Last Verified: 2026-04-20 | First Added: 2026-04-20
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