Products

Sage (AI Care Manager)
Ellipsis Health
Mental & Behavioral Health AI
Sage is an emotionally intelligent AI voice agent by Ellipsis Health that uses vocal biomarkers to screen for and monitor depression and anxiety, providing 24/7 virtual care management for healthcare organizations. It automates patient engagement, assessments, and clinical support, while ensuring HIPAA, SOC2 Type 2, and GDPR compliance.

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About Ellipsis Health

Ellipsis Health is a healthcare AI company that has pioneered the development of a voice-based vital sign to quantify and manage symptoms of depression and anxiety. The company’s core product is Sage, an emotionally intelligent AI voice agent designed to analyze human speech for detecting signs of depression and anxiety. Sage leverages patented vocal biomarker technology and conversational AI, trained on millions of clinical conversations, to assess stress, depression, and anxiety from less than 60 seconds of natural speech.

For physicians, Ellipsis Health’s technology offers a tool to enhance mental health screening and care management. Sage integrates seamlessly into existing workflows through mobile apps, patient portals, and telehealth visits, providing data-driven insights without significant operational disruption. This allows healthcare providers to identify patients who need mental health support more quickly and efficiently, address clinical staffing shortages, and manage patient care costs. The technology aims to improve patient outcomes, particularly for underserved populations including children and adolescents, by offering a scalable and non-invasive way to assess mental well-being and aid in early detection and more effective treatment planning.

Ellipsis Health partners with hospitals, health insurance plans, and specialty care organizations, acting as a screening and triaging stage to positively impact the quality of care, shorten the time to diagnosis, drive workflow efficiencies, and reduce costs. The company emphasizes patient safety and data security, with HIPAA and SOC2 Type 2 compliant infrastructure, secure data handling, and transparent AI decision-making processes. Sage also integrates with major electronic medical record (EMR) systems and customer relationship management (CRM) platforms, ensuring continuous data flow and patient care coordination.

What Physicians Need to Know

Specialization
Ellipsis Health specializes in AI-powered vocal biomarker technology to detect and monitor signs of depression, anxiety, and stress from speech. Their core product, Sage, is an AI care manager that automates patient engagement, assessments, and care management interactions using conversational AI. They operate at the intersection of AI-driven healthcare automation, the mental health crisis, and data-driven care models.
Key Differentiators
Ellipsis Health's primary differentiator is its proprietary 'Empathy Engine' and patented vocal biomarker technology. This technology analyzes both the linguistic content (what is said) and acoustic features (how it is said, including tone, timing, and emotional markers) of speech to generate clinically validated assessments. They are recognized for being the first in the world to prove the effectiveness of voice-based 'vital signs for depression and anxiety' in peer-reviewed academic papers. Their approach focuses on 'automating empathy' rather than just task automation, aiming to improve patient experience and clinical outcomes. The technology is also designed for speed and non-invasiveness, requiring less than 60 seconds of natural speech for screening.
Technology Stack
Ellipsis Health's technology stack includes natural language processing (NLP) and acoustic models. Their AI care manager, Sage, is trained on millions of actual clinical dialogue data from doctors and therapists, enabling it to learn medical-specific language patterns and empathetic expressions. They utilize patented vocal biomarker technology that analyzes acoustic parameters such as pitch, intonation, speed, pauses, and voice tremors in real-time. The company also partners with NVIDIA for integration of NVIDIA Riva Parakeet speech recognition into Sage's conversational AI platform to enhance speed, transcription accuracy, and real-time responsiveness.
Physician Tip

For physicians, Ellipsis Health's Sage AI care manager offers several benefits. It can significantly expand clinical capacity by automating routine patient interactions, assessments, and follow-up calls, freeing up clinicians to focus on more complex tasks. The technology provides real-time triage, enabling faster identification of patients needing urgent intervention. Its clinically validated vocal biomarkers offer an objective and non-invasive tool for screening and continuous monitoring of depression and anxiety, which can lead to earlier detection and intervention. The seamless integration with existing workflows through mobile apps, patient portals, and telehealth visits minimizes operational disruption. Furthermore, Sage's empathetic AI approach aims to maintain personalized communication with patients, improving engagement and outcomes, particularly for underserved populations.

Ellipsis Health's Sage platform is designed for seamless integration with existing healthcare infrastructure. It supports integration with major Electronic Medical Record (EMR) systems, including Epic via FHIR, ensuring continuous data flow and patient care coordination. It also integrates with Customer Relationship Management (CRM) systems for appointment scheduling, task tracking, and reminders. Ellipsis Health has partnered with Salesforce to integrate Sage directly into Salesforce Health Cloud, providing quick installation and implementation for assessments and care management. Other integrations include HealthEdge's Care Solutions platform for AI-powered virtual nursing and Augmedix for enhancing clinical visits with mental health screenings. The company emphasizes an API-first architecture for flexible integration and supports standard FHIR protocols. Ellipsis Health is HIPAA, GDPR, and SOC2 compliant, with ongoing efforts towards HITRUST certification, ensuring secure data handling and patient privacy.

Products by Ellipsis Health

1 product in the directory

Sage (AI Care Manager)
Ellipsis Health
Mental & Behavioral Health AI
Sage is an emotionally intelligent AI voice agent by Ellipsis Health that uses vocal biomarkers to screen for and monitor depression and anxiety, providing 24/7 virtual care management for healthcare organizations. It automates patient engagement, assessments, and clinical support, while ensuring HIPAA, SOC2 Type 2, and GDPR compliance.

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Press & Coverage

PR Newswire
Ellipsis Health unveils Sage, the emotionally intelligent AI Care Manager, backed by $45M from Salesforce, Khosla Ventures, and CVS Ventures
Ellipsis Health announced a $45 million Series A funding round led by Salesforce, Khosla Ventures, and CVS Health Ventures, coinciding with the launch of Sage, their AI Care Manager. Sage uses patented vocal biomarker technology to provide emotionally intelligent care management for patients with complex needs.
2025-06
PR Newswire
Ellipsis Health selected as key partner in CMS Health Tech Ecosystem to drive national healthcare AI transformation
Ellipsis Health has been chosen as a key partner in the Centers for Medicare and Medicaid Services (CMS) Health Tech Ecosystem, a program aimed at modernizing healthcare through AI. The company's AI care manager, Sage, will contribute to developing conversational AI for personalized patient support and specialized tools for diabetes and obesity management.
2025-07
Business Wire
Ellipsis Health and Clearstep Partner to Advance Clinically Intelligent Care Management
Ellipsis Health announced a partnership with Clearstep to integrate Clearstep's clinical triage APIs into Sage, Ellipsis Health's AI Care Manager. This collaboration aims to provide a more complete care management experience, combining empathetic voice-based check-ins with clinically validated symptom assessment and care navigation.
2026-04
Ellipsis Health
Ellipsis Health and NVIDIA Partner to Deliver More Natural AI Care Management Conversations
Ellipsis Health is collaborating with NVIDIA to enhance its AI care manager, Sage, by integrating NVIDIA Riva Parakeet automatic speech recognition technology. This partnership aims to make Sage faster and more responsive, leading to more natural and empathetic patient interactions.
2025-11
Fierce Healthcare
CVS, Salesforce back Ellipsis Health's $45M series A raise - Fierce Healthcare
Ellipsis Health secured $45 million in Series A funding, co-led by Salesforce, Khosla Ventures, and CVS Health Ventures, to advance its AI-powered voice agent, Sage. Sage is designed to address gaps in care management by providing empathetic, high-quality support to patients with complex needs.
2025-06
HIT Consultant
Ellipsis Health Raises $45M to Launch Sage, an Emotionally Intelligent AI Care Manager
Ellipsis Health closed a $45 million Series A funding round to launch Sage, an AI Care Manager that uses an 'Empathy Engine' built on vocal biomarker technology. The platform aims to expand staffing capacity, reduce operating costs, and improve patient engagement in care management.
2025-06
PubMed
Feasibility of a Machine Learning-Based Smartphone Application in Detecting Depression and Anxiety in a Generally Senior Population - PubMed
A study published in PubMed demonstrated the feasibility of the Ellipsis Health App in using voice recordings to screen for depression and anxiety across various age groups, including seniors. The machine learning models, utilizing Transformer methodology, showed promising performance in detecting these conditions.
2022-04
Ellipsis Health
Ellipsis Health announced a Rising Star in Mental & Behavioral Health at the Digital Health Awards
Ellipsis Health was recognized as a 'Rising Star in Mental & Behavioral Health' at the 2023 Digital Health Awards. The company was among 40 winners selected from over 1,500 applicants for their innovative use of technology to improve healthcare.
2023-10

Frequently Asked Questions

Ellipsis Health offers Sage, an emotionally intelligent AI Care Manager, which utilizes patented vocal biomarker technology to detect and monitor the severity of depression and anxiety symptoms. Sage automates critical patient interactions such as health risk assessments, post-discharge check-ins, and medication adherence follow-ups, aiming to expand provider capacity and streamline workflows.
Ellipsis Health is HIPAA and GDPR compliant, and is actively pursuing HITRUST certification. Their AI system maintains SOC 2 compliance, employs end-to-end encryption for data at rest and in transit, and undergoes regular third-party security audits, all governed by an internal AI Ethics Policy.
While specific pricing details are not publicly disclosed, Ellipsis Health licenses its AI voice agent, Sage, to hospitals, health insurance plans, and specialty care organizations. The solution is designed to help mitigate clinical staffing shortages and manage patient care costs, suggesting a B2B licensing or subscription-based model tailored to organizational needs.
Ellipsis Health provides 'white glove implementation' services, including collaborative refinement through monitored test calls and custom prompt development based on existing clinical protocols. They offer comprehensive support from initial implementation through ongoing optimizations and expansions, including joint monitoring to ensure quality and effectiveness.
Ellipsis Health has formed strategic partnerships with major players like Salesforce, integrating Sage into Salesforce Health Cloud for seamless workflow integration. They also partner with NVIDIA for enhanced speech recognition, Clearstep for AI-powered triage, HealthEdge for virtual nursing, and Pega for behavioral health solutions, and are a key partner in the CMS Health Tech Ecosystem.
Ellipsis Health demonstrates strong financial stability, having raised a total of $75 million across three funding rounds, including a significant $45 million Series A in June 2025. This funding, backed by investors such as Salesforce, Khosla Ventures, and CVS Health Ventures, indicates robust investor confidence and supports their plans for expanding into new areas like pediatric mental health and international markets.

Investors

Who's funded Ellipsis Health.

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