Products

Neuroreader
Brainreader
Clinical Decision Support & Reference
Neuroreader is an FDA-cleared AI-enabled brain volumetric analysis tool that quantifies 83 brain regions from routine MRI to enhance diagnostic precision for neurodegenerative disorders.

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About Brainreader

Brainreader is a Danish healthcare AI company that specializes in quantitative brain MRI analysis through its flagship software, Neuroreader®. Founded in 2011, the company develops FDA-cleared and CE-marked medical device software that provides clinicians with objective, reproducible brain volumetric data. Neuroreader® automates the analysis of 3D T1-weighted MRI scans, quantifying over 65 to 83 specific brain structures, including the hippocampus, cortical lobes, and ventricles, in under 10 minutes. This rapid analysis helps physicians in the early detection, diagnosis, and monitoring of neurodegenerative diseases by identifying subtle atrophy patterns that may be invisible to the human eye.

For physicians, Neuroreader® serves as a clinical decision-support tool, offering objective data in the form of volumes (mL), percentiles, and Z-scores, and enabling longitudinal tracking of brain volume changes over time. This quantitative insight is crucial for conditions such as Alzheimer’s disease and dementia, mild cognitive impairment (MCI), traumatic brain injury (TBI), and epilepsy. The software integrates seamlessly into existing PACS or can be used via web upload, streamlining workflow without requiring extensive staff retraining or additional patient time. By providing accurate and actionable insights, Brainreader aims to empower healthcare professionals to make more informed clinical decisions, design effective treatment plans, and ultimately improve patient outcomes.

Focus Areas

AI-enabled brain volumetric analysis neurodegenerative disease detection Alzheimer's disease traumatic brain injury (TBI) epilepsy medical image processing quantitative MRI neuroimaging

Business Intelligence

Key InvestorsDahlgren Capital, Investo Capital, CBC Investment Group, Bevica Foundation, Insero, Syddansk Innovation
PartnershipsINFINITT North America (2022)
TechnologyCloud-based platform, AI-powered deep learning algorithms, integrates with PACS, processes DICOM images from MRI scans
FDA Clearances1 (Neuroreader®) cleared products (estimated)

What Physicians Need to Know

Specialization
Brainreader specializes in AI-enabled brain volumetric analysis for neurodegenerative diseases, traumatic brain injury (TBI), and epilepsy. Their flagship product, Neuroreaderu00ae, quantifies 83 brain regions from routine MRI scans.
Key Differentiators
Neuroreaderu00ae is FDA-cleared and CE-marked, providing fast (under 10 minutes), accurate, and clinically validated quantitative brain MRI analysis. It offers objective, reproducible data, eliminating subjectivity in brain volume assessment. The software also provides longitudinal tracking to monitor disease progression and treatment effectiveness.
Technology Stack
Brainreader's Neuroreaderu00ae utilizes advanced AI and deep learning algorithms to post-process DICOM images from MRI scans, performing automated segmentation and volumetric analysis. It compares patient brain volumes against a validated normative database adjusted for age, sex, and head size.
Neurodegenerative Disease Detection
The software enhances diagnostic precision for conditions like Alzheimer's disease by identifying subtle atrophy patterns, such as progressive hippocampal and temporal lobe atrophy. It can help differentiate Alzheimer's from other conditions like depression, vascular dementia, and TBI.
Traumatic Brain Injury (TBI)
Neuroreaderu00ae provides objective volumetric measurements and left-right asymmetry indices for TBI, helping to detect subtle structural changes and differentiate TBI atrophy patterns from those of Alzheimer's.
Epilepsy
The software assists in identifying changes in brain volume associated with epilepsy, including subtle abnormalities that might be missed by visual inspection.
Medical Image Processing & Quantitative MRI
Brainreader transforms routine 3D T1 MRI scans into quantitative volumetric reports, measuring 83 brain structures in milliliters, percentiles, and Z-scores. This provides objective, reproducible data for more precise insights than traditional visual interpretation.
Physician Tip

For physicians, Brainreader's Neuroreaderu00ae offers a powerful tool for earlier and more confident diagnosis and monitoring of neurodegenerative diseases, TBI, and epilepsy. The automated, quantitative reports, delivered in under 10 minutes, can significantly reduce the time to diagnosis and free up valuable physician time. The objective data and longitudinal tracking capabilities allow for better differentiation between conditions with overlapping symptoms, more informed treatment planning, and clearer communication with patients and their families about disease progression. Integrating Neuroreaderu00ae into existing MRI workflows is designed to be seamless, whether through web-based access, a mediation server, or direct PACS integration.

Brainreader's Neuroreaderu00ae is designed for seamless integration into existing clinical workflows. It supports PACS integration for automated image routing and report delivery, and also offers secure web portal access and mediation server options. This flexibility allows for easy deployment across various clinical and enterprise environments, including single-site clinics and large health systems.

Products by Brainreader

1 product in the directory

Neuroreader
Brainreader
Clinical Decision Support & Reference
Neuroreader is an FDA-cleared AI-enabled brain volumetric analysis tool that quantifies 83 brain regions from routine MRI to enhance diagnostic precision for neurodegenerative disorders.

What the Web Says

Brainreader is a Danish medical device company that developed Neuroreader, FDA-cleared and CE marked software for analyzing MRI scans to detect changes in brain volume. The software aims to assist in the early diagnosis of neurodegenerative diseases like Alzheimer's, epilepsy, and depression, as well as traumatic brain injuries. Neuroreader is designed to provide fast and accurate measurements of brain structures, significantly reducing the time radiologists spend on analyzing MRI scans.

Overall: Positive

Strengths

  • Fast and accurate detection of brain volume changes compared to traditional methods.
  • FDA-cleared and CE marked software, providing a level of regulatory approval that competitors may lack.
  • Measures a large number of specific brain structures (up to 83 in customizable reports).
  • Reduces MRI read times for radiologists from approximately 24 minutes to 10 minutes or less.
  • Helps clinicians identify early and sensitive biomarkers of neurodegenerative diseases.
  • Provides objective analysis by comparing brain volumes against normative datasets, eliminating bias.

Limitations

  • Limited information available regarding company/employer reviews on major platforms like Glassdoor or G2, making it difficult to assess workplace sentiment.
  • Some general AI review platforms on Reddit express concerns about the accuracy and privacy of uploading medical data to online AI tools, though these are not specific to Brainreader.
  • The available reviews are primarily focused on the product (Neuroreader) and are largely from medical/healthcare IT publications or studies, rather than direct user reviews on common software review sites.
  • No self-serve pricing is mentioned for the product.

Based on reviews from: DOTmed.com, HealthTech Alpha, Blackford Analysis, BrainReader (company website), Journal of Alzheimer's Disease, Capterra, G2, Reddit

Last updated: 2026-06-19

Videos

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Press & Coverage

Brainreader
Brainreader Secures $7.3M to Drive Global Expansion of AI-Powered Brain Diagnostics
Danish medtech company Brainreader A/S has successfully completed a financing round of USD 7.3 million (EUR 6.6 million) to accelerate the global rollout of its AI-driven diagnostic platform Neuroreader. The funding will be used to scale commercial operations, particularly in the U.S. healthcare market, and continue the development of new features and clinical applications.
2025-05
Brainreader
New Study Highlights Diagnostic Power of Neuroreader in Alzheimer's
A BMC Neurology study demonstrates that MRI volumetry can accurately distinguish major neurocognitive disorders by identifying distinct patterns of brain volume loss using Brainreader's Neuroreader software. This peer-reviewed study highlights the power of AI-enabled MRI volumetry in differentiating between common neurocognitive disorders.
2024-09
Brainreader
Brainreader Partners with Phenome Health on Landmark Million-Person Brain Health Trial
Brainreader Inc. is in advanced negotiations to provide its Neuroreaderu00ae software as the exclusive volumetric brain analytics platform for Phenome Health's Beyond the Human Genome Project, a one-million-person trial. This landmark trial aims to redefine data, science, and clinical practice around dementia treatment and understanding worldwide.
2022-11
Brainreader
Brainreader and INFINITT North America Announce Strategic Partnership
INFINITT North America and Brainreader Inc. announced a strategic partnership to expand the adoption of Brainreader's FDA-cleared Neuroreaderu00ae software. This collaboration aims to improve the speed, accuracy, and depth of understanding for doctors in diagnosing and treating neurological conditions.
2022-06
Brainreader
Brainreader Announces 3-Year R&D Partnership with Aalborg University to Advance AI in Neurodegenerative Disease Research
Brainreader has entered into a three-year research and development partnership with Aalborg University to advance AI in neurodegenerative disease research. This partnership aims to further develop Brainreader's AI-driven neuroimaging software.
2021-07
Imaging Technology News
Neuroreader Software Speeds Detection of Brain Volume Changes
Brainreader launched its Neuroreader software, which has the potential to speed the detection of changes in a patient's brain volume, a key indicator in the diagnosis of degenerative brain diseases. The software analyzes MRI scans and benchmarks them against a healthy brain tissue database in minutes.
2015-08
News-Medical.Net
Research study validates neuroreader for accurate and fast measurement of brain volumes
A research study published in the Journal of Alzheimer's Disease validated Neuroreader as accurate and fast for measuring brain volumes, particularly hippocampal volume, a biomarker for Alzheimer's Disease. The software was found to be over 87% accurate compared to manual segmentation but significantly faster.
2015-10
FDA
510(k) Premarket Notification - K140828
The FDA granted 510(k) clearance to Brainreader Aps for their Neuroreader device, classifying it under neurological devices. This regulatory announcement indicates the device is substantially equivalent to legally marketed predicate devices.
2015-02

Frequently Asked Questions

Brainreader's flagship product is Neuroreaderu00ae, an FDA-cleared and CE-marked AI-enabled software that performs quantitative brain volumetric analysis from routine MRI scans. It quantifies up to 83 brain structures, providing objective data and identifying subtle atrophy patterns that aid in the earlier detection and monitoring of neurodegenerative diseases like Alzheimer's and other dementias.
For Alzheimer's disease, Neuroreaderu00ae helps identify progressive hippocampal and temporal lobe atrophy, a classic hallmark of the disease. In cases of Traumatic Brain Injury (TBI), it provides objective volumetric measurements, left-right asymmetry indices, and standardized segmentation to highlight subtle structural changes often missed by visual inspection. While the provided information doesn't detail specific epilepsy detection mechanisms for Neuroreaderu00ae, it is mentioned as a condition where brain volume changes are key indicators, and the software can help identify these changes.
Neuroreaderu00ae is FDA-cleared (Class II) and CE-marked, and Brainreader is ISO 13485 certified and HIPAA compliant. All personal health information (PHI) processed by Neuroreaderu00ae is handled securely in accordance with HIPAA requirements, and data can be anonymized prior to upload or routed via a mediation server.
Neuroreaderu00ae is designed for seamless integration into routine MRI protocols. It processes standard 3D T1-weighted MRI sequences from 1.5T or 3.0T scanners, with images securely uploaded or routed via PACS integration. The software then automatically segments and quantifies brain structures, generating a comprehensive report typically in under 10 minutes.
Brainreader provides guided onboarding, including user training, product instructions, and workflow support to ensure proper implementation and use of Neuroreaderu00ae. They also offer customer support via phone and email for sales, support, and general inquiries.
Brainreader, founded in 2011, is a Series A company that has raised $14.6M in funding. They have established strategic partnerships with companies like INFINITT North America to integrate Neuroreaderu00ae into PACS systems, and Blackford Analysis to bring advanced medical image analysis to healthcare professionals. They are also in advanced negotiations with Phenome Health for a large-scale brain health trial.
While specific pricing details are not publicly available in the provided information, Neuroreaderu00ae is sold as a software service on a per-use or subscription basis. In the U.S., the adoption of CPT codes for brain volumetry is creating new reimbursement pathways, and Neuroreaderu00ae is applicable for the recently issued, reimbursable CPT III codes 0865T and 0866T for longitudinal brain quantitative MRI analysis.

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