Products

1up Platform
1upHealth
Developer Tools & APIs
1upHealth offers a FHIR-first data platform for health plans to acquire, manage, and use healthcare data, simplifying health data exchange and ensuring regulatory compliance.

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About 1upHealth

1upHealth is a healthcare AI company that provides a FHIR-enabled health data platform designed for claims and clinical data acquisition, exchange, and computation. Their platform allows healthcare organizations, including health plans, state Medicaid agencies, digital health organizations, and Accountable Care Organizations (ACOs), to securely access, manage, and analyze large volumes of healthcare data. The company’s mission is to unlock health data and improve industry outcomes, making healthcare data broadly available to help individuals live longer, healthier, and happier lives.

For physicians, 1upHealth’s platform facilitates seamless data interoperability between disparate healthcare systems, enabling the aggregation and sharing of medical data from electronic health records and wearable devices. This allows for a more comprehensive, longitudinal view of patient health, which can lead to enhanced healthcare outcomes and reduced costs. The platform supports regulatory compliance, digital quality measures, population health analytics, and value-based contracts, assisting healthcare professionals in optimizing data-driven initiatives and improving patient care.

Focus Areas

healthcare data interoperability FHIR platform health data exchange population health value-based care regulatory compliance data analytics EHR integration claims data clinical data

Business Intelligence

Key InvestorsSixth Street Partners, F-Prime Capital, Jackson Square Ventures, Eniac Ventures, Social Leverage, MassChallenge
PartnershipsInnovaccer, Advanced Health (Oregon Coordinated Care Organization)
TechnologyCloud-native, FHIR-first data platform, lakehouse architecture, API-enabled, open-source technologies, AWS Fargate, Teradata Analytics Platform, Cloudflare CDN, Go, Express

What Physicians Need to Know

Healthcare Data Interoperability
1upHealth specializes in unlocking and exchanging healthcare data, making it accessible and usable across the healthcare ecosystem. They offer a FHIR-first data platform that connects and activates health data securely and at scale.
FHIR Platform
Their core offering is a FHIR-enabled health data platform that facilitates the acquisition, exchange, and analysis of clinical and claims data. They provide a managed, HIPAA-compliant FHIR API cloud server supporting all FHIR R4 resources.
Health Data Exchange
1upHealth simplifies health data exchange for payers, providers, and digital health companies, enabling them to move faster and operate with confidence. They support patient-driven data ingestion and provide secure, standardized API connections for scalable data exchange.
Population Health
They offer solutions like '1up Population Connect' to access clinical data from top EHR vendors at the patient population level, enabling data-driven decisions to improve financial and health outcomes.
Value-Based Care
1upHealth strengthens value-based care relationships by providing providers with the necessary data to improve quality performance and supports initiatives through timely, automated data sharing.
Regulatory Compliance
They help health plans meet CMS interoperability requirements, including CMS-9115-F and CMS-0057-F, for Patient Access, Provider Access, Payer-to-Payer Data Exchange, and Electronic Prior Authorization APIs.
Data Analytics
The platform integrates with analytics tools like Power BI and Tableau, and their lakehouse architecture enables advanced analytics and AI enablement with AI-ready, longitudinal data.
EHR Integration
1upHealth connects to over 10,000 health facilities and integrates with major EHR vendors like Epic, Oracle, and athenahealth, enabling direct access to Electronic Health Records.
Claims Data & Clinical Data
They acquire, manage, exchange, analyze, and use both clinical and claims data, combining them to drive better quality and costs in healthcare.
Physician Tip

For physicians, 1upHealth stands out by providing a more complete patient history directly at the point of care, reducing administrative burdens associated with data sharing, and supporting timely and appropriate member care. Their platform enables access to critical patient data beyond EHR limitations, facilitating AI-driven tools to function independently of the EHR. They simplify prior authorization processes, leading to faster decisions and reduced delays in treatment. The ability to aggregate and analyze population-level data can also help physicians gain insights and improve how patients receive care across disparate systems.

1upHealth offers seamless integrations with existing operational and clinical systems, including EHRs, utilization management (UM) systems, care management, and analytics platforms. They provide a 'one-to-many' network connectivity model, reducing the need for costly point-to-point integrations. Their platform supports various data formats, including X12 (837 and 278), FHIR bundles, and custom flat files or CSV formats, and converts HL7v2 and CCDA data into FHIR. This flexibility allows organizations to leverage their existing infrastructure while benefiting from 1upHealth's interoperability and compliance expertise.

Products by 1upHealth

1 product in the directory

1up Platform
1upHealth
Developer Tools & APIs
1upHealth offers a FHIR-first data platform for health plans to acquire, manage, and use healthcare data, simplifying health data exchange and ensuring regulatory compliance.

What the Web Says

1upHealth is a health-tech company that provides a FHIR-based healthcare data platform, enabling interoperable data exchange, patient-driven data ingestion, and integration with analytics tools. The company aims to improve healthcare outcomes and reduce costs by bridging the gap between patient-centered data and provider needs. Employer reviews generally highlight a positive work environment with collaborative and supportive management, opportunities for growth, and a good work-life balance. Product reviews praise its efficiency in streamlining data management and improving productivity, particularly for RFP processes.

Overall: Positive

Strengths

  • FHIR-based platform for efficient health data exchange and interoperability.
  • Supports patient-driven data ingestion.
  • Integrates with analytics tools like Power BI and Tableau.
  • Positive work environment with talented and collaborative teams.
  • Supportive management that encourages career growth.
  • Streamlines RFP processes and centralizes information, improving productivity.

Limitations

  • Some Reddit discussions from 2023 raised concerns about potential job scams associated with the company, though others affirmed its legitimacy.
  • Limited public product reviews on major platforms like G2 and Capterra, with some reviews potentially referring to a different company named '1up' or 'OneUp' that offers RFP automation or social media scheduling.
  • Pricing information for the healthcare data platform is not publicly listed.
  • No free trial or free version of the product is offered.
  • Some users of a product named '1up' on G2 mentioned the interface for responding to and editing questions on the web took some getting used to.

Based on reviews from: Indeed.com, Elion Health, Slashdot, Zippia, Google Search, KLAS Research, Spotsaas, G2, Capterra, Reddit, Gartner Peer Insights

Last updated: 2026-07-27

Videos

News, demos, and interviews about 1upHealth.

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Press & Coverage

1upHealth (via ACCESS Newswire)
1upHealth Announces 1up Gateway to Simplify CMS-0057-F Compliance for Health Plans
1upHealth launched the 1up Gateway to help health plans comply with the CMS Interoperability and Prior Authorization Final Rule (CMS-0057-F) by the January 1, 2027 deadline, offering a managed API and compliance layer for existing FHIR infrastructure.
2026-07
1upHealth
1upHealth Sets a New Standard for Health Data Interoperability: New Platform Delivers 'Health Data, On Demand'
1upHealth unveiled the latest release of its 1up Platform at HIMSS25, featuring a modern lakehouse architecture designed to scale with healthcare's data needs and enhance real-time access, management, and analytics for improved operational efficiency and patient outcomes.
2025-03
1upHealth Blog
Why 1upHealth Keeps All Healthcare Data Operations in the United States
1upHealth emphasizes its commitment to trust, security, and integrity by maintaining 100% US-based healthcare data operations, ensuring tighter alignment, faster implementations, and adherence to US laws for patient privacy and security.
2025-08
Journal of Comparative Effectiveness Research (via Becaris Publishing)
Evidation and 1upHealth collaborate to expand real-world data utilization in health research
Evidation and 1upHealth partnered to enhance real-world data sharing in health research, allowing individuals to seamlessly consent to share health records and combine them with other real-world data sources for a more holistic view of patient experiences.
2024-10
1upHealth Blog
Observations from HLTH 2024: Making healthcare work better for all
1upHealth shared observations from HLTH 2024, highlighting the focus on practical applications of AI, empowering patients with control over their health data, and addressing interoperability challenges and opportunities.
2024-10
1upHealth Blog
Revolutionizing Prior Authorization with 1upHealth | Smarter ePA Solutions
1upHealth is working to revolutionize prior authorization through digitization, leveraging its FHIR-native, cloud-powered platform to streamline processes and align with regulatory changes like CMS-0057.
2025-06
1upHealth
Health Data Cloud Leader 1upHealth Raises $40 Million in Series C
1upHealth secured $40 million in Series C funding led by Sixth Street Growth, with plans to expand product development and customer growth teams to accelerate the digital transformation of the healthcare industry in the cloud.
2023-04
1upHealth
1upHealth Secures $25M Series B Funding
1upHealth announced a $25 million Series B funding round led by F-Prime Capital, with participation from existing investors, to grow and evolve its FHIRu00ae connectivity & compute platform.
2021-04

Frequently Asked Questions

1upHealth offers a FHIR-native platform designed to aggregate and normalize healthcare data from various sources, including EHRs and claims, into a single, interoperable format. This facilitates seamless health data exchange and provides a unified view of patient information, crucial for both individual patient care and population health management.
By centralizing and standardizing clinical and claims data, 1upHealth enables providers to gain a comprehensive understanding of their patient populations. This data can be used for risk stratification, identifying care gaps, and monitoring outcomes, all of which are essential for succeeding in value-based care models and improving population health.
1upHealth's platform is built on FHIR standards, directly addressing regulatory mandates for data interoperability. The company prioritizes data security and privacy, adhering to HIPAA regulations and other relevant compliance frameworks to ensure the safe and compliant exchange and storage of sensitive health information.
1upHealth utilizes a robust API-first approach for integrating with various EHR systems, allowing for efficient extraction and ingestion of clinical data. Beyond EHRs, the platform is designed to incorporate and harmonize diverse data types, including claims data, lab results, and other relevant healthcare information, creating a holistic patient record.
1upHealth offers powerful data analytics capabilities that allow users to derive actionable insights from their aggregated health data. This includes customizable dashboards, reporting tools, and the ability to perform complex queries, empowering physicians and administrators to monitor key performance indicators, identify trends, and optimize care delivery.
1upHealth typically employs a subscription-based pricing model, which can vary depending on the scale of data, number of users, and specific features required. They provide comprehensive support, including implementation assistance, technical guidance, and ongoing customer service to ensure successful platform adoption and utilization.
1upHealth has established partnerships with various healthcare organizations, technology vendors, and innovators to expand its interoperability network and enhance its platform's capabilities. The company has demonstrated strong growth and stability, backed by significant funding and a clear vision for advancing healthcare data exchange and innovation.

Investors

Who's funded 1upHealth.

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