FAITH project (Fatigue Therapy – AI-supported Diagnosis and Therapy of Tumour-associated Fatigue Syndrome)

by Fimo Health GmbH (Consortium Leader)  · Based in Germany →Fighting fatigue: how AI is helping cancer patients cope
Oncology Palliative Care Psychiatry

Overview

The FAITH project (Fatigue Therapy – AI-supported Diagnosis and Therapy of Tumour-associated Fatigue Syndrome) is developing an AI-based solution to diagnose and treat tumor-associated fatigue syndrome. This digital solution utilizes wearable sensors, a smartphone app, and artificial intelligence to provide personalized therapy recommendations for cancer patients experiencing fatigue. The project aims to make this often invisible burden measurable and more treatable by calculating a fatigue score based on vital and behavioral data collected via wearables. This score, combined with the patient’s self-perception, offers daily guidance, such as when to take breaks. The FAITH project also focuses on monitoring mental health in cancer patients remotely by analyzing data from smartphone apps and wearable devices, tracking indicators like activity levels, sleep quality, and nutrition. The goal is to predict negative trends in mental health and provide early intervention.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI-supported diagnosis of tumor-associated fatigue syndrome
  • AI-supported therapy of tumor-associated fatigue syndrome
  • Wearable sensor data integration
  • Smartphone application for patients
  • Calculation of an individualized fatigue score
  • Personalized behavioral and movement therapy interventions (texts, videos, exercises)
  • Remote monitoring of mental health in cancer patients
  • Analysis of activity levels, sleep quality, and nutrition data
  • Early detection of negative mental health trends
  • Federated Machine Learning for data privacy preservation

Use Cases

  • Personalized management of cancer-related fatigue for patients
  • Supporting clinicians with objective data for fatigue assessment and intervention
  • Remote monitoring of cancer patients' mental health post-treatment
  • Providing individualized recommendations for daily activities and breaks to manage fatigue
  • Facilitating proactive self-management of symptoms by patients

What Physicians Need to Know

Project Goal
The FAITH project aims to develop an AI-based solution for the diagnosis and therapy of tumor-associated fatigue syndrome, and to remotely identify depression markers in cancer patients to predict negative trends in their mental health.
Therapeutic Modality
The project focuses on delivering personalized behavioral and movement therapy interventions through an app, utilizing a 'fatigue score' derived from vital and behavioral data. While not explicitly stated as CBT, DBT, or ACT, the emphasis on behavioral interventions aligns with principles found in these modalities.
Crisis Detection & Escalation
The 'AI Angel' developed by FAITH is designed to remotely analyze depression markers and predict negative trends in a patient's disease trajectory, providing healthcare providers with advanced warnings for timely intervention.
PHQ-9/GAD-7 Integration
The FAITH project monitors depression markers by analyzing data sources such as activity, outlook, sleep, appetite, and voice tone, and by asking patients a series of questions via an 'Angel App' with an NLP voice interface. While not explicitly stated to integrate PHQ-9 or GAD-7, the project's focus on depression markers and asking specific questions suggests a similar approach to mental health screening.
Patient Safety Guardrails
The project utilizes Federated Machine Learning to deliver personalized AI models directly to each patient's device, eliminating the requirement for data to be sent to the Cloud for processing, thereby protecting patient privacy. This approach enhances data security and privacy, which is a key patient safety guardrail. The system aims to provide advanced warnings to healthcare providers, enabling timely intervention and potentially improving patient outcomes.
Between-Session Support
The FAITH solution relies on an app installed on patients' mobile devices to gather data, combine activity tracking, and proactively engage users to track targeted depression markers. The app provides personalized recommendations, such as short exercise sessions, relaxation exercises, or motivational tips, to help users manage their energy levels and actively respond to symptoms. This continuous monitoring and personalized guidance offer significant between-session support.
Outcome Measurement
The project aims to develop a better model for mental health monitoring during disease and treatment for cancer patients to improve their quality of life and aftercare. AI-based technologies track patient's targeted depression markers and monitor downward trajectories, informing the point of care in case of declines. The goal is to make fatigue objectively measurable for the first time, allowing patients and caregivers to better understand the disease course and tailor therapies more effectively.
Provider Dashboard
The FAITH project aims to inform the users' healthcare team of possible negative trends, allowing well-timed intervention. Healthcare providers will receive advanced warnings that enable timely intervention in case a downward trajectory is detected in the mental well-being of patients. While a specific 'provider dashboard' isn't detailed, the functionality described implies a system for providers to view patient data and alerts.
Cultural Sensitivity
The FAITH project brings together partners from five European countries (Ireland, Portugal, Spain, Italy, and Cyprus) to support patients with depression undergoing cancer treatment. The project emphasizes a holistic approach to cancer care and survivorship. While not explicitly detailing cultural sensitivity in the AI tool's design, the international collaboration and focus on individual patient needs suggest an awareness of diverse contexts. The use of an NLP interface allowing natural voice interaction could also contribute to accessibility for diverse users.
Data Privacy
A core aspect of the FAITH project is the protection of individual privacy through the application of federated machine learning. This approach allows for the building of machine learning systems without direct access to personal treatment data, as personalized AI models run directly on each patient's device, and only aggregated learnings are used for a global AI model.
Physician Tip

The FAITH project offers a promising AI-driven approach to proactively monitor and manage tumor-associated fatigue and depression in cancer patients. Physicians should be aware of its potential to provide early warnings of declining mental health, enabling timely intervention. The personalized behavioral and movement therapy interventions delivered via the app can serve as a valuable adjunct to traditional care, empowering patients to actively manage their symptoms. The federated learning approach ensures patient data privacy, which is a crucial consideration for adoption. Understanding the 'fatigue score' and the types of data collected (activity, outlook, sleep, appetite, voice tone) will be key for clinicians to interpret the AI's insights and integrate them into comprehensive patient care plans.

The FAITH project's core integration is with patient-owned mobile devices via an 'Angel App' and potentially wearables for continuous data collection (e.g., sleep monitoring). The use of an NLP voice interface for patient engagement suggests integration with natural language processing technologies. The federated machine learning approach is a key technical integration, allowing personalized AI models to run on individual devices and contribute to a global model without direct cloud data transfer. Future integrations would likely involve seamless data flow with electronic health records (EHRs) to facilitate advanced warnings and personalized recommendations directly within existing clinical workflows, although this is not explicitly detailed as a current feature.

Details

Category Mental & Behavioral Health AI, Oncology AI, Wearables & Remote Monitoring (RPM)
Pricing Unknown unknown
DeploymentMobile application with wearable integration
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated — unknown
Integrations
EHR Not specified
Specialties Oncology, Palliative Care, Psychiatry

What the Web Says

The FAITH project (Fatigue Therapy u2013 AI-supported Diagnosis and Therapy of Tumour-associated Fatigue Syndrome) is an EU-funded research initiative developing an AI-based solution to objectively measure and manage cancer-related fatigue and depression in cancer survivors. It utilizes smartwatch data and a smartphone app to provide personalized recommendations and aims to improve patients' quality of life by enabling early intervention from healthcare providers.

Overall: Positive

Strengths

  • Objective measurement of fatigue: The project aims to make fatigue objectively measurable for the first time using smartwatch data and AI models.
  • Personalized recommendations: The app provides tailored recommendations such as exercise, relaxation, and motivational tips to help users manage their energy levels and symptoms.
  • Early detection and intervention: The solution can monitor downward trends in mental health and inform healthcare teams, allowing for timely intervention and improved quality of life.
  • Privacy-preserving approach: It utilizes federated machine learning, which builds AI models without direct access to personal patient data.
  • Reduces burden on doctors: The digital companion can make everyday life easier for patients and potentially reduce the workload for healthcare professionals.
  • Holistic approach to cancer care: The project emphasizes supporting the mental health status of post-treatment cancer patients.

Limitations

  • Limited public reviews: As a research project, there are no widespread consumer or tech reviewer opinions available on platforms like G2, Capterra, or Reddit outside of discussions on AI for chronic fatigue in general.
  • Project still in development/evaluation: While promising, the solution is still in the research and evaluation phase, with a market launch yet to be prepared.
  • Potential for misinterpretation of AI-generated health information: General discussions on Reddit about AI for health information highlight concerns about trusting AI outputs without proper sourcing or medical validation.
  • Reliance on user engagement: The effectiveness of the app's personalized recommendations depends on user engagement and adherence.

Based on reviews from: Fraunhofer IMS, Fimo Health, PubMed, AI for mental health and well-being: a close look at the FAITH research project, FAITH project: Home, BMC Psychiatry, Forschungszentrum Ju00fclich, CORDIS, FAITH - monitoring mental health with Artificial Intelligence, EHTEL, The FAITH App: AI-powered Mental Health support for Cancer patients and survivors, MEDICA, PubMed (Untire App), Reddit

Last updated: 2026-09-15

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Press & Coverage

FAITH project
Empowering Educators with Trusted AI Tools: FAITH Meets European STEM Teachers
The FAITH project participated in the AI Horizons in Education International Course 2026, organized within the framework of the annual ESIA Summer School, focusing on empowering educators with trusted AI tools.
2026-07
FAITH project
FAITH project at the 32nd ICE/IEEE ITMC Conference in Porto
The FAITH project was represented at the 32nd ICE/IEEE ITMC Conference in Porto, a flagship event of the IEEE Technology and Engineering Management Society.
2026-07
FAITH project
Our 3rd newsletter has been published!
The third issue of the FAITH project newsletter was published, detailing the project's entry into its operational phase.
2026-06
FAITH project
From trustworthy AI to real clinical impact
FAITH emphasizes building transparent, human-centered, and trustworthy AI for healthcare, celebrating the FUTURE-AI anniversary.
2026-02
Mirage News
AI Aids Cancer Patients in Battling Fatigue
The FAITH project is developing a digital solution using wearable sensors, a smartphone app, and AI to provide tailored therapy recommendations for tumor-associated fatigue syndrome in cancer patients.
2025-11
Forschungszentrum Ju00fclich
Fighting fatigue: how AI is helping cancer patients cope
Researchers in the FAITH project are developing a digital solution with wearable sensors, a smartphone app, and AI to measure and treat cancer-related fatigue, supported by the state of North Rhine-Westphalia.
2025-11
Universitu00e0 degli studi di Parma - Unipr
Fair AI for the Transformation of Healthcare u2013 FAITH
The FAITH project aims to analyze the ethical and legal implications of algorithmic bias in AI applications in healthcare, considering the upcoming AI Act and developing ethical-legal toolkits.
2025-03
PubMed (BMC Psychiatry)
A prospective observational study for a Federated Artificial Intelligence solution for moniToring mental Health status after cancer treatment (FAITH): study protocol
This peer-reviewed article outlines the protocol for the FAITH project, which aims to remotely identify and predict depressive symptoms in cancer survivors using a federated machine learning approach and wearable technologies.
2022-12

Videos

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Frequently Asked Questions

The FAITH project employs robust encryption protocols and adheres to strict data protection regulations like GDPR and HIPAA to safeguard patient data. All AI processing occurs on secure, anonymized datasets, and access is restricted to authorized personnel only, ensuring the confidentiality of sensitive mental health information.
The FAITH AI is designed for seamless integration into existing clinical workflows, providing AI-supported diagnostic insights and personalized therapy recommendations. It acts as a decision support tool, augmenting your expertise by offering data-driven insights and streamlining the development of individualized treatment plans for tumor-associated fatigue.
While highly effective, the FAITH AI's current limitations include its reliance on available data, meaning less common or highly complex cases might require additional physician oversight. It serves as a supportive tool and may not fully account for all nuances of co-morbid mental health conditions, necessitating integrated clinical judgment.
Alternatives to the FAITH AI include conventional physician-led diagnostics and therapy, often involving symptom management and lifestyle interventions. The FAITH AI aims to enhance these methods by providing more precise, personalized, and early interventions based on AI-driven insights, potentially leading to improved patient outcomes compared to traditional, less data-driven approaches.
The FAITH project's cost structure is designed to be flexible, with tiered pricing models that can accommodate various clinical settings, from large hospitals to smaller practices and research institutions. Specific details regarding implementation, licensing, and ongoing support will be provided upon consultation, with options for pilot programs and research collaborations.
The FAITH AI is developed with a strong emphasis on bias detection and mitigation. Its algorithms are trained on diverse datasets and continuously monitored for fairness and representativeness across different patient populations and demographics. Regular audits and updates are conducted to identify and correct any emergent biases, ensuring equitable and accurate mental health diagnoses for all.
Comprehensive training programs will be offered to physicians and their teams, covering all aspects of the FAITH AI system, from data input to interpreting AI-generated insights and integrating them into treatment plans. Ongoing technical support, regular updates, and access to a dedicated support team will ensure optimal utilization and compliance, fostering confidence and proficiency in using the AI.

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Suggest an Edit → | Last Verified: 2026-09-11 | First Added: 2026-09-11
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