Annalise-AI

Sydney, Australia  All Australia companies → Founded 2019
Imaging AI Specialist
Critical Care Emergency Medicine Neurology Radiology
Neurology AI Radiology & Imaging AI Triage & ER/ICU AI
Acquired/Corporate Backed — N/A (Operating subsidiary of Harrison.ai, which has raised over USD $240 million)

Products

Annalise Enterprise CTB Triage-OH
Annalise-AI Pty
Neurology AI
Annalise Enterprise CTB Triage-OH is an FDA-cleared AI software tool designed to identify suspected obstructive hydrocephalus in non-contrast brain CT scans, aiding in worklist prioritization and accelerating critical diagnoses.
Annalise Enterprise CXR Triage Trauma
Annalise-AI Pty
Radiology & Imaging AI
Annalise Enterprise CXR Triage Trauma is an FDA-cleared AI software tool that aids clinicians in the rapid assessment and triage of adult chest X-ray cases by identifying suspected radiological findings like pleural effusion and pneumoperitoneum, and up to 124 other findings, to optimize workflow and improve diagnostic accuracy.

See all 2 products →

About Annalise-AI

Annalise-AI is a global health-tech company specializing in advanced artificial intelligence solutions for medical imaging, designed to serve as a “second set of digital eyes” for clinicians. Their comprehensive AI platforms, such as Annalise Enterprise CXR and Annalise Enterprise CTB, are engineered to assist radiologists and healthcare providers in interpreting radiological studies with enhanced accuracy and efficiency. These solutions are trained on extensive, expert-annotated datasets, enabling the detection of a broad spectrum of findings—up to 124 on chest X-rays and up to 130 on non-contrast head CTs.

The company’s AI tools integrate seamlessly into existing clinical workflows, providing immediate results that can aid in critical triage and worklist prioritization. This capability helps ensure that time-sensitive cases, such as those involving pneumothorax, tension pneumothorax, or obstructive hydrocephalus, are flagged promptly, leading to quicker diagnoses and interventions. By improving diagnostic confidence and reducing the risk of missed findings, Annalise-AI aims to alleviate radiologist workload, lessen fatigue, and ultimately drive better patient outcomes globally.

Annalise-AI’s patient-first approach is clinician-led, stemming from a deep understanding of the challenges in medical imaging. Their solutions have received regulatory clearances in numerous countries, including FDA approvals in the US, and are deployed in hundreds of healthcare facilities worldwide, supporting millions of patients annually. Beyond current offerings, the company’s research and development efforts extend to areas like orthopedic diseases, respiratory tract diseases, and women’s health, indicating a commitment to expanding AI’s impact across diverse medical fields.

Focus Areas

Medical imaging AI radiology AI chest X-ray (CXR) analysis non-contrast head CT analysis AI-assisted triage and notification (CADt) diagnostic decision support workflow optimization detection of pneumothorax tension pneumothorax pleural effusion pneumoperitoneum vertebral compression fracture acute subdural/epidural hematoma acute subarachnoid hemorrhage intra-axial hemorrhage intraventricular hemorrhage obstructive hydrocephalus orthopedic diseases respiratory tract diseases women's health

Business Intelligence

Key InvestorsI-MED Radiology Network, Harrison.ai
PartnershipsMass General Brigham, NHS Trusts (UK), Hong Kong public emergency departments, Nuance Communications (a Microsoft Company), Ramsay Sime Darby Health Care (Malaysia), Gleneagles Kuala Lumpur (Malaysia), Raleigh Radiology
AcquisitionsAcquired by Harrison.ai (December 4, 2024); subsequently rebranded as Harrison.ai Radiology (October 7, 2025)
TechnologyDeep learning, convolutional neural networks, multi-view and multi-modal imaging inference (CXR and CT), worklist prioritization algorithms, low-latency inference engines, large-scale expert-annotated training datasets, radiology-focused foundational AI models, cloud-native (implied by AI marketplace participation)
FDA Clearances10 cleared products (estimated)

What Physicians Need to Know

Core Modality Specialization
Annalise-AI specializes in advanced AI for medical imaging, primarily focusing on comprehensive analysis of Chest X-rays (CXR) and non-contrast Head CTs. Their solutions are designed to assist radiologists in interpreting these critical imaging modalities.
Comprehensive AI Detection
A key differentiator is their extensive detection capability, identifying up to 124 findings on Chest X-rays and up to 130 findings on non-contrast Head CTs. This broad coverage includes both common and subtle or rare pathologies, surpassing many single-finding AI solutions.
AI-Assisted Triage & Notification (CADt)
Annalise-AI's Computer-Aided Detection and Triage (CADt) solutions automatically and rapidly monitor all CXR and non-contrast Head CT exams for time-sensitive critical findings. These findings are then flagged and prioritized within the radiology worklist, ensuring immediate attention for urgent cases.
Diagnostic Decision Support
The AI acts as a 'second pair of eyes,' significantly improving radiologist diagnostic accuracy (e.g., by 45% for CXR and 32% for Head CT) and reducing interpretation errors, particularly for subtle findings that might otherwise be missed.
Workflow Optimization
By automating initial review and prioritizing critical cases, Annalise-AI helps reduce reporting times (e.g., by 12% for CXR and 11% for Head CT), lessens radiologist fatigue, and streamlines overall radiology workflow efficiency, addressing increasing workloads.
Regulatory & Clinical Validation
Annalise-AI holds multiple FDA 510(k) clearances for its CXR and Head CT findings, including a 'Breakthrough Device' designation for obstructive hydrocephalus. Their solutions are rigorously validated through peer-reviewed clinical studies demonstrating improved radiologist performance.
Clinician-Led & Data-Driven Development
The AI models were developed with a patient-first approach, trained on nearly 1 million unique, de-identified patient studies, hand-labeled by over 140 fully trained consultant radiologists from diverse datasets across three continents, ensuring clinical relevance and robustness.
Physician Tip

For physicians, Annalise-AI (now operating as Harrison.ai Radiology) offers a powerful adjunctive tool to enhance diagnostic confidence and efficiency. Leverage its comprehensive detection capabilities as an objective 'second pair of eyes' to minimize the risk of missing subtle or critical findings, especially in high-volume settings. Utilize the AI's rapid triage and notification features to prioritize urgent cases, ensuring timely patient intervention and potentially reducing turnaround times. While the AI provides robust decision support, always integrate its output with your clinical expertise and other patient information for final diagnostic decisions. The system's design, informed by extensive clinician feedback, aims to reduce cognitive load and burnout, allowing you to focus on complex cases and patient care.

Annalise-AI solutions are engineered for seamless integration into existing radiology workflows. They interface with standard clinical imaging systems like PACS/RIS, providing AI results in DICOM format (Secondary Capture) and can be configured to feed into worklist software for prioritization and notification. The platform is typically used on PC workstations in conjunction with medical imaging viewers, ensuring a low-friction adoption into current clinical environments. Deployment services are offered to facilitate integration, and the company also makes its solutions available through AI marketplaces.

Products by Annalise-AI

2 products in the directory

Annalise Enterprise CTB Triage-OH
Annalise-AI Pty
Neurology AI
Annalise Enterprise CTB Triage-OH is an FDA-cleared AI software tool designed to identify suspected obstructive hydrocephalus in non-contrast brain CT scans, aiding in worklist prioritization and accelerating critical diagnoses.
Annalise Enterprise CXR Triage Trauma
Annalise-AI Pty
Radiology & Imaging AI
Annalise Enterprise CXR Triage Trauma is an FDA-cleared AI software tool that aids clinicians in the rapid assessment and triage of adult chest X-ray cases by identifying suspected radiological findings like pleural effusion and pneumoperitoneum, and up to 124 other findings, to optimize workflow and improve diagnostic accuracy.

What the Web Says

Annalise.ai is an Australian company specializing in AI-powered medical imaging solutions for radiology. Their products, Annalise Enterprise CXR and Annalise Enterprise CTB, are designed to improve diagnostic accuracy and efficiency for radiologists by detecting a comprehensive range of findings on chest X-rays and non-contrast head CT scans. The company's solutions are used in various settings, including emergency care, and for screening purposes for conditions like lung cancer and stroke. While there is strong evidence and positive feedback regarding the product's performance in clinical studies and from some users, some Reddit discussions indicate concerns about false positives and the potential for AI to miss critical findings.

Overall: Mixed

Strengths

  • Significantly improves radiologists' diagnostic accuracy (e.g., 32% increase for CTB).
  • Reduces overall reading time for radiologists (e.g., 11% faster for CTB).
  • Detects a comprehensive range of findings (up to 124 for CXR and 130 for CTB), exceeding competitors.
  • Reduces human bias and minimizes the risk of misdiagnosis.
  • Integrates seamlessly with existing PACS, RIS, and EMR systems.
  • Helps prioritize critical cases, leading to quicker diagnoses and patient treatments.

Limitations

  • Some Reddit users report the AI can miss things and overcall others, leading to false positives.
  • False positives can lead to increased workload for radiologists who need to explain them to other doctors and patients.
  • Concerns raised about the origin of the training data, specifically regarding patient consent for anonymized scans used from a large Australian medical imaging lab.
  • Limited public reviews on platforms like G2, Glassdoor, and Capterra specifically for Annalise.ai products, making it difficult to gauge widespread user sentiment from these sources.
  • One Reddit user mentioned that if the AI were a resident, it would be failing the rotation due to false positives.

Based on reviews from: BioWorld, Annalise.ai (Case Studies), techAU, Reddit, Harrison.ai, Microsoft Marketplace, Imaging Technology News, G2, ProvenExpert

Last updated: 2026-07-17

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Press & Coverage

Applied Radiology
Annalise.ai Rebrands as Harrison.ai Radiology in Move to Unify Global Imaging AI Platform
Annalise.ai announced its rebranding to Harrison.ai Radiology, consolidating its radiology solutions under a unified global brand to align its mission and offerings. The change reflects the company's scaling international presence and plans to expand its AI footprint beyond radiology into new clinical service lines.
2025-10
National Reconstruction Fund Corporation
NRFC invests $32 million in lifesaving medical Artificial Intelligence provider Harrison.ai
The National Reconstruction Fund Corporation (NRFC) invested $32 million in Harrison.ai, the parent company of Annalise.ai, to further develop its radiology and pathology diagnostic capabilities and expand globally. This funding will support the company's mission to detect and diagnose medical conditions like cancer quickly and accurately.
2025-01
PMC (Emergency Medicine Journal)
Evaluating the impact of AI assistance on decision-making in emergency doctors interpreting chest X-rays: a multi-reader multi-case study - PMC
A study published in Emergency Medicine Journal evaluated Annalise Enterprise CXR, a commercially available AI tool, and found that AI assistance increased correct diagnoses by 5.9% in emergency doctors interpreting chest X-rays. The study also noted an increase in confidence in diagnosis with AI assistance.
2025-10
Disruptivity Times
Annalise.ai Radiology Model Threatens Premium Scanner Economics | Disruptivity Times
Annalise.ai is rolling out a new foundation model in Europe, trained on 100 million radiology studies, which clinical trials show outperforms individual radiologists in identifying 124 distinct chest X-ray conditions. This software creates a hardware-agnostic diagnostic layer that could impact the pricing power of major medical equipment manufacturers.
2031-04
Signify Research
SPI Medical Imaging: NHS Tender Wins Put Annalise.ai in the Spotlight | Signify Research
Annalise.ai has been selected as the preferred provider by six imaging networks in England through NHS England's new AI Diagnostic Fund. This will make Annalise.ai's AI-powered decision-support system, which identifies up to 124 findings on chest X-rays, available to clinicians performing 2.8 million chest X-rays annually.
2024-06
PMC (Journal of Imaging Informatics in Medicine)
Text Report Analysis to Identify Opportunities for Optimizing Target Selection for Chest Radiograph Artificial Intelligence Models - PMC
A study analyzing radiology report text for chest radiographs highlighted that pulmonary nodules and acute rib fractures were the findings most often missed by radiologists, according to analysis of the Annalise software. The study suggests opportunities for designing CXR AI systems to increase radiologist efficiency.
2024-01
Mass General Brigham
Mass General Brigham and Annalise.ai collaborate to deploy, develop and research AI imaging tools
Mass General Brigham and Annalise.ai announced a collaboration to develop, productize, and deploy diagnostic-focused AI solutions in medical imaging, including implementing Annalise Triage across the Mass General Brigham system. This partnership builds on their existing relationship and aims to reduce diagnostic uncertainty and improve patient outcomes.
2023-11
Annalise.ai (via Google Cloud)
Annalise.ai Receives FDA Clearance and Breakthrough Device Designation
Annalise.ai received 510(k) clearance from the U.S. FDA for the triage and notification of obstructive hydrocephalus on non-contrast brain CT scans, along with Breakthrough Device Designation for the same tool. This expands Annalise.ai's U.S. portfolio to ten FDA-cleared findings.
2023-09

Frequently Asked Questions

Annalise.ai provides comprehensive AI solutions, including Annalise Triage, Annalise Enterprise CXR, and Annalise Enterprise CTB, designed to assist clinicians in interpreting radiological imaging studies. These solutions offer extensive detection capabilities, identifying up to 124 findings on chest X-rays and up to 130 findings on non-contrast head CTs. They support various clinical use cases, from emergency care to lung cancer diagnosis and stroke detection.
Annalise.ai's AI-assisted triage and notification (CADt) system, such as Annalise Triage, enhances radiology workflow by prioritizing studies with suspected critical findings. This prioritization helps reduce report turnaround times and ensures urgent cases receive immediate attention, thereby optimizing diagnostic decision support for radiologists facing high imaging volumes.
For chest X-rays, Annalise.ai's solutions can detect conditions like pneumothorax, tension pneumothorax, pleural effusion, pneumoperitoneum, and vertebral compression fracture. On non-contrast head CTs, they identify acute subdural/epidural hematoma, acute subarachnoid hemorrhage, intra-axial hemorrhage, intraventricular hemorrhage, obstructive hydrocephalus, mass effect, and vasogenic edema. Annalise.ai holds multiple FDA 510(k) clearances for these findings and has received FDA Breakthrough Device Designation for obstructive hydrocephalus.
Annalise.ai operates on a subscription-based pricing model, typically involving an annual fee per institution and a one-off implementation charge covering installation, integration, and staff training. Notably, their solution for obstructive hydrocephalus on non-contrast head CT has secured a Medicare New Technology Add-on Payment (NTAP) in the US, providing additional reimbursement for hospitals utilizing this technology.
Annalise.ai offers comprehensive support through its Sales and Customer Success Team, guiding healthcare providers from implementation to effective use and ensuring customer satisfaction. They also have a Professional Services Team for system configuration and integration with existing PACS/RIS workflows. Key partnerships include being a joint venture of I-MED Radiology Network and Harrison.ai, and collaborations with entities like Nuance Communications (a Microsoft Company), Mass General Brigham, and Avreo.
Annalise.ai was established as a joint venture between I-MED Radiology Network, Australia's largest diagnostic chain, and healthcare technology company Harrison.ai, which has raised over $150 million in venture capital. The company's solutions are clinically deployed in over 40 countries and across more than 1,000 customer sites globally, including over 40 NHS trusts, demonstrating significant market penetration and stability. Annalise.ai was acquired by Harrison.ai on December 4, 2024, and its radiology solutions are now marketed under Harrison.ai Radiology.

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