Products

Avenda Health AI Prostate Cancer Planning Software
Avenda Health
Clinical Decision Support & Reference
Avenda Health's Unfold AI is an FDA-cleared, AI-based decision support software that creates 3D cancer maps from patient data to precisely visualize prostate cancer extent, aiding physicians in treatment planning and decision-making for personalized care.

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About Avenda Health

Avenda Health is a healthcare AI company dedicated to revolutionizing personalized prostate cancer care. Their flagship product, Unfold AI (formerly iQuest), is an FDA-cleared, multi-modal AI decision support platform that provides physicians with precise, patient-specific 3D maps of prostate cancer. This technology integrates existing diagnostic information, such as imaging, pathology, biomarkers, and clinical data, with deep-learning algorithms to reveal the full extent of the cancer, including microscopic ‘tentacles’ often missed by traditional imaging like MRI.

For physicians, Unfold AI enhances the ability to identify cancer extent by a significant margin, improving diagnostic accuracy and confidence in treatment planning. The platform supports various treatment options, including focal therapy (such as laser ablation with their FocalPoint System), active surveillance, and decision-making for whole-gland treatments. By enabling more precise interventions that target only cancerous tissue while sparing healthy surrounding tissue, Avenda Health aims to improve patient outcomes, preserve quality of life by minimizing side effects (like urinary and sexual dysfunction), and establish a new standard of care in prostate cancer management.

Focus Areas

Prostate cancer care personalized medicine AI-driven diagnostics treatment planning focal therapy medical devices deep learning 3D mapping oncology

Business Intelligence

Key InvestorsVCapital, Plug & Play Ventures, Wealthing VC Club, SCP Ventures
PartnershipsBioscienceLA, EDAP TMS SA, Urology Associates (PrecisionPoint®)
TechnologyUnfold AI (AI-powered 3D cancer mapping platform, formerly iQuest), FocalPoint System (focal laser ablation device), deep learning algorithms, cloud-based clinical decision support
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Prostate Cancer Care
Avenda Health is dedicated to transforming prostate cancer care by offering a personalized future, aiming to improve patient outcomes, preserve quality of life, and establish a new standard of care.
Personalized Medicine
They create tailored treatment plans and patient-specific cancer maps using a patient's diagnostic data (imaging, pathology, biomarkers, clinical information), providing physicians with informed guidance for treatment decisions.
AI-Driven Diagnostics
Their flagship product, Unfold AI, is an FDA-cleared, multimodal AI decision support platform that accurately identifies the extent of prostate cancer, significantly enhancing diagnostic capabilities beyond traditional imaging.
Treatment Planning
Avenda Health's software maps a patient's cancer in 3D, giving physicians precise information and confidence to make care decisions, enabling them to better determine treatment approaches and avoid leaving cancerous tissue behind.
Focal Therapy
They offer the FocalPoint laser ablation system, designed for targeted treatment of localized prostate cancer in an office setting under local anesthesia, aiming to minimize side effects and preserve urinary and sexual function.
Medical Devices
Avenda Health develops proprietary medical devices like the FocalPoint System and the AI-enabled Unfold AI (formerly iQuest), which are FDA-cleared for soft tissue ablation and AI-based decision support, respectively.
Deep Learning & 3D Mapping
Utilizing deep learning algorithms, their Unfold AI software maps a patient's cancer in 3D, providing never-before-available 3D visualization and precise information for confident care plan decisions.
Oncology
Specializing in prostate cancer oncology, Avenda Health is at the forefront of using AI to vastly improve the tools available to physicians for more effective patient treatment.
Physician Tip

For physicians, Avenda Health's Unfold AI offers a 'superhuman' ability to accurately identify the extent of prostate cancer, improving diagnostic capabilities by up to 45 times and achieving 84% accuracy in predicting cancer extent. This leads to more precise and personalized treatment planning, allowing for tailored interventions that can preserve patient quality of life by sparing healthy tissue. The platform provides unprecedented confidence in care decisions and supports the shift towards less invasive, in-office focal therapy options. Furthermore, the inclusion of Unfold AI in the AMA's 2024 CPT code set as a Category III code means it is now billable by insurance, improving patient access to this advanced personalized prostate cancer care.

Avenda Health's Unfold AI platform is designed to integrate with a patient's existing diagnostic data, including MRI images, biopsy information, pathology reports, and biomarkers. They have also established collaborations to integrate Unfold AI with other technologies, such as the PrecisionPointu00ae Transperineal Access System for safer and more precise biopsies, and with EDAP TMS's Focal Oneu00ae robotic HIFU platform for AI-assisted focal therapy procedures.

Products by Avenda Health

1 product in the directory

Avenda Health AI Prostate Cancer Planning Software
Avenda Health
Clinical Decision Support & Reference
Avenda Health's Unfold AI is an FDA-cleared, AI-based decision support software that creates 3D cancer maps from patient data to precisely visualize prostate cancer extent, aiding physicians in treatment planning and decision-making for personalized care.

What the Web Says

Avenda Health is an AI healthcare company focused on personalized prostate cancer care. Their flagship product, Unfold AI, is an FDA-cleared platform that uses artificial intelligence to map prostate tumors in 3D, aiming to improve treatment decisions and outcomes. Studies have shown Unfold AI to be significantly more accurate than standard methods in identifying cancer extent, leading to a higher likelihood of patients being cancer-free. While there is extensive information on their product's efficacy and potential, public reviews specifically from platforms like G2, Glassdoor, Capterra, or Reddit for Avenda Health as a company or employer are limited.

Overall: Positive

Strengths

  • Unfold AI significantly improves the accuracy of identifying prostate cancer extent compared to standard methods.
  • The technology aids physicians in surgical planning and treatment decision-making.
  • Unfold AI has been shown to reduce the underestimation of cancer extent and increase negative margin rates.
  • The platform has the potential to enable more patient-specific treatment for various cancers beyond prostate cancer.
  • Avenda Health's technology has received FDA clearance.
  • The company's approach aims to improve outcomes for men, reduce healthcare costs, and preserve quality of life.

Limitations

  • Unfold AI is a new technology and is not yet fully covered by insurance.
  • The study cases for Unfold AI were derived from a single institution, which may not represent performance in broader populations.
  • The ground truth for studies was set by a single expert pathologist, lacking a method to address observer dependency.
  • Specific employer or product reviews on major platforms like G2, Glassdoor, Capterra, or Reddit are not readily available.
  • The average annual salary for employees at Avenda Health Inc. is an estimation and does not originate from the company's factual payroll records or survey data.

Based on reviews from: Optics.org, BioWorld, AuntMinnie, Avenda Health Official Website, PR Newswire, SimplyHired, Vertex AI Search

Last updated: 2026-07-17

Videos

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Press & Coverage

PR Newswire
Avenda Health's Unfold AI to be Deployed at University of Michigan Health, Expanding AI-Guided Prostate Cancer Care to the Midwest for the First Time
Avenda Health announced that University of Michigan Health has adopted its Unfold AI platform, marking the first deployment of the AI-driven 3D prostate cancer mapping technology in the Midwest to support personalized treatment decisions.
2026-05
MedTech Innovator
Avenda Health's Unfold AI Included in Expanded Medicare Physician Fee Schedule Across West Coast and Mountain West Regions
Avenda Health's Unfold AI is now included in Medicare's Physician Fee Schedules across the West Coast and Mountain West regions, providing clearer reimbursement pathways for urologists in physician office settings.
2026-04
Avenda Health
AI Enhances Ability to Identify Extent of Prostate Cancer
A new study published in The Journal of Urology demonstrates that Avenda Health's Unfold AI technology significantly improves physicians' ability to identify the extent of prostate cancer, with AI-assisted identification improving accuracy by 45 times.
2024-06
EDAP TMS SA
EDAP and Avenda Health Launch World's First AI-Assisted Focal Oneu00ae Robotic HIFU Procedures
EDAP TMS SA and Avenda Health announced a collaboration to offer personalized prostate cancer care, launching the world's first AI-assisted Focal One robotic high-intensity focused ultrasound (HIFU) procedures using Avenda's Unfold AI technology.
2024-09
Applied Radiology
Avenda Health's Mapping Technology, Unfold AI Enhances Prostate Cancer Staging Accuracy
A pilot study revealed that Avenda Health's Unfold AI, an AI-powered cancer mapping tool, significantly outperforms conventional MRI in accurately predicting prostate cancer spread, achieving a 92% accuracy rate compared to 52% for traditional MRI.
2025-05
PR Newswire
Avenda Health Raises $10M in Series B, Innovating Detection and Treatment for Prostate Cancer Care
Avenda Health, an AI healthcare company focused on personalized prostate cancer care, announced it has raised $10M in Series B funding to accelerate the use of its AI-enabled patient management software, iQuest, and continue clinical evidence development.
2022-08
Los Angeles Business Journal
Avenda Health Raises $10M, Gets FDA Clearance To Begin Clinical Trial of Laser Heat Technology
Avenda Health secured $10 million in Series B funding and received FDA clearance for a randomized clinical trial of its laser ablation technology to treat prostate cancer.
2022-09
Urology Times
FDA clears path for trial of AI-enabled focal therapy in prostate cancer
The FDA granted investigational device exemption (IDE) to Avenda Health's FocalPoint ablation system, powered by iQuest AI software, enabling a new trial comparing this AI-driven treatment to standard care for localized prostate cancer.
2022-08

Frequently Asked Questions

Avenda Health's Unfold AI platform utilizes deep learning and patient-specific data, including MRI images, biopsy information, and pathology reports, to generate a personalized 3D cancer probability map of the prostate. This detailed visualization helps physicians accurately identify the extent and location of the cancer, enabling more informed decisions and tailored treatment plans that aim to improve outcomes and preserve quality of life.
AI and deep learning are central to Avenda Health's Unfold AI, which creates precise 3D cancer maps by analyzing patient data, significantly outperforming traditional MRI in identifying cancer extent. This AI-driven diagnostic information then guides focal therapy treatments, such as Avenda's FocalPoint laser ablation system or in collaboration with EDAP's Focal One HIFU, allowing for targeted tumor destruction while sparing healthy tissue.
Avenda Health's primary product is Unfold AI, an FDA-cleared AI-based decision support platform that integrates patient-specific data from prostate imaging, biopsies, and pathology to generate a customized 3D cancer estimation map. This map provides physicians with a precise visualization of the cancer's location and extent, crucial for treatment selection, planning, guidance, and follow-up.
Avenda Health's focal therapy, guided by Unfold AI, offers the benefit of precisely targeting cancerous lesions while minimizing damage to surrounding healthy tissue, which is crucial for preserving urinary and sexual function. This approach has been shown to improve tumor margin creation and reduce the underestimation of cancer extent, potentially leading to better oncologic control and reduced recurrence rates compared to whole-gland treatments.
Avenda Health ensures compliance through rigorous processes, with its Unfold AI platform having received FDA 510(k) clearance as an AI-based decision support software. Their FocalPoint laser ablation system also obtained FDA Breakthrough Device Designation and an Investigational Device Exemption. The company utilizes a robust Quality Management System (QMS) to manage documentation and streamline regulatory adherence.
Avenda Health is dedicated to bringing its technology to all practices and physicians treating prostate cancer, aiming to improve outcomes and create a new standard of care. While specific training programs are not detailed, their platform is designed to support physicians with critical information, comprehensive insights, and planning guidance, implying an inherent support structure for implementation. They also provide resources for physicians and patients to understand and utilize Unfold AI.
Avenda Health's Unfold AI has secured a new Category III CPT code (0898T) and a national payment rate from CMS, which facilitates reimbursement for healthcare providers utilizing the technology. While pricing for Unfold AI can vary by provider and may not be fully covered by all insurance plans, the company is actively working to standardize prices and encourages direct discussion with doctors regarding costs. Avenda Health also engages in strategic partnerships, such as their collaboration with EDAP TMS for AI-assisted HIFU procedures.

Investors

Who's funded Avenda Health.

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