Products

Neuroreader
Brainreader
Clinical Decision Support & Reference
Neuroreader is an FDA-cleared AI-enabled brain volumetric analysis tool that quantifies 83 brain regions from routine MRI to enhance diagnostic precision for neurodegenerative disorders.

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About Brainreader

Brainreader is a Danish healthcare AI company that specializes in quantitative brain MRI analysis through its flagship software, Neuroreader®. Founded in 2011, the company develops FDA-cleared and CE-marked medical device software that provides clinicians with objective, reproducible brain volumetric data. Neuroreader® automates the analysis of 3D T1-weighted MRI scans, quantifying over 65 to 83 specific brain structures, including the hippocampus, cortical lobes, and ventricles, in under 10 minutes. This rapid analysis helps physicians in the early detection, diagnosis, and monitoring of neurodegenerative diseases by identifying subtle atrophy patterns that may be invisible to the human eye.

For physicians, Neuroreader® serves as a clinical decision-support tool, offering objective data in the form of volumes (mL), percentiles, and Z-scores, and enabling longitudinal tracking of brain volume changes over time. This quantitative insight is crucial for conditions such as Alzheimer’s disease and dementia, mild cognitive impairment (MCI), traumatic brain injury (TBI), and epilepsy. The software integrates seamlessly into existing PACS or can be used via web upload, streamlining workflow without requiring extensive staff retraining or additional patient time. By providing accurate and actionable insights, Brainreader aims to empower healthcare professionals to make more informed clinical decisions, design effective treatment plans, and ultimately improve patient outcomes.

Focus Areas

AI-enabled brain volumetric analysis neurodegenerative disease detection Alzheimer's disease traumatic brain injury (TBI) epilepsy medical image processing quantitative MRI neuroimaging

Business Intelligence

TechnologyCloud-based platform, AI-powered deep learning algorithms, integrates with PACS, processes DICOM images from MRI scans

What Physicians Need to Know

Specialization
Brainreader specializes in AI-enabled brain volumetric analysis for neurodegenerative diseases, traumatic brain injury (TBI), and epilepsy. Their flagship product, Neuroreaderu00ae, quantifies 83 brain regions from routine MRI scans.
Key Differentiators
Neuroreaderu00ae is FDA-cleared and CE-marked, providing fast (under 10 minutes), accurate, and clinically validated quantitative brain MRI analysis. It offers objective, reproducible data, eliminating subjectivity in brain volume assessment. The software also provides longitudinal tracking to monitor disease progression and treatment effectiveness.
Technology Stack
Brainreader's Neuroreaderu00ae utilizes advanced AI and deep learning algorithms to post-process DICOM images from MRI scans, performing automated segmentation and volumetric analysis. It compares patient brain volumes against a validated normative database adjusted for age, sex, and head size.
Neurodegenerative Disease Detection
The software enhances diagnostic precision for conditions like Alzheimer's disease by identifying subtle atrophy patterns, such as progressive hippocampal and temporal lobe atrophy. It can help differentiate Alzheimer's from other conditions like depression, vascular dementia, and TBI.
Traumatic Brain Injury (TBI)
Neuroreaderu00ae provides objective volumetric measurements and left-right asymmetry indices for TBI, helping to detect subtle structural changes and differentiate TBI atrophy patterns from those of Alzheimer's.
Epilepsy
The software assists in identifying changes in brain volume associated with epilepsy, including subtle abnormalities that might be missed by visual inspection.
Medical Image Processing & Quantitative MRI
Brainreader transforms routine 3D T1 MRI scans into quantitative volumetric reports, measuring 83 brain structures in milliliters, percentiles, and Z-scores. This provides objective, reproducible data for more precise insights than traditional visual interpretation.
Physician Tip

For physicians, Brainreader's Neuroreaderu00ae offers a powerful tool for earlier and more confident diagnosis and monitoring of neurodegenerative diseases, TBI, and epilepsy. The automated, quantitative reports, delivered in under 10 minutes, can significantly reduce the time to diagnosis and free up valuable physician time. The objective data and longitudinal tracking capabilities allow for better differentiation between conditions with overlapping symptoms, more informed treatment planning, and clearer communication with patients and their families about disease progression. Integrating Neuroreaderu00ae into existing MRI workflows is designed to be seamless, whether through web-based access, a mediation server, or direct PACS integration.

Brainreader's Neuroreaderu00ae is designed for seamless integration into existing clinical workflows. It supports PACS integration for automated image routing and report delivery, and also offers secure web portal access and mediation server options. This flexibility allows for easy deployment across various clinical and enterprise environments, including single-site clinics and large health systems.

Products by Brainreader

1 product in the directory

Neuroreader
Brainreader
Clinical Decision Support & Reference
Neuroreader is an FDA-cleared AI-enabled brain volumetric analysis tool that quantifies 83 brain regions from routine MRI to enhance diagnostic precision for neurodegenerative disorders.

What the Web Says

Brainreader is a Danish medical device company that has developed Neuroreader, an AI-enabled software designed to analyze MRI scans of the brain to detect subtle changes in brain volume. This technology aims to assist in the early diagnosis and monitoring of neurodegenerative diseases like Alzheimer's, epilepsy, and depression, as well as traumatic brain injuries. The software provides quantitative, reproducible measurements of brain structures, offering a more objective assessment than visual interpretation alone.

Overall: Positive

Strengths

  • Provides objective, reproducible brain volume measurements.
  • Aids in earlier detection of neurodegenerative diseases and traumatic brain injuries.
  • Analyzes 45-83 specific brain structures.
  • Delivers automated reports in less than five minutes.
  • Integrates seamlessly into existing clinical workflows.
  • FDA-cleared and supported by peer-reviewed research.

Limitations

  • Some general concerns exist regarding the evidence gap for automated MRI analysis in dementia.
  • AI tools for MRI analysis are still in development and may have a high margin of error, especially in distinguishing normal anatomical differences from lesions.
  • AI diagnostic aids can be expensive, potentially increasing overall healthcare costs.
  • Some AI interview platforms, which may share similar underlying AI technology, are criticized for being less personal and lacking in interactive questioning or data storage for later comparisons.
  • The accuracy of AI models in real-world data may differ from testing model accuracy.

Based on reviews from: AuntMinnie, Brainreader Official Website, Reddit, PitchBook

Last updated: 2026-09-21

Videos

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Press & Coverage

Brainreader Inc.
Brainreader Secures $7.3M to Drive Global Expansion of AI-Powered Brain Diagnostics
Danish medtech company Brainreader A/S has completed a $7.3 million (EUR 6.6 million) financing round to accelerate the global rollout of its AI-driven diagnostic platform Neuroreader. The funding will support commercial operations, particularly in the U.S. healthcare market, and the development of new features and clinical applications.
2025-05
EU-Startups
Danish medtech startup Brainreader raises u20ac6.6M funding
Brainreader, a Danish medtech company, has raised u20ac6.6 million to accelerate the global launch of its AI-based diagnostic tool, Neuroreader, which is approved in Europe and the US and automatically measures brain volume from MRI scans. The investment will help expand its business, especially in the US, and add new features and medical uses to its platform.
2025-05
Dahlgren Capital
Dahlgren Capital Leads u20ac6.6M Investment in Danish Medtech Innovator Brainreader
Dahlgren Capital led a u20ac6.6 million (USD 7.3 million) strategic investment in Brainreader, a Danish medtech company, with continued support from Investo Capital. This funding will accelerate Brainreader's commercial expansion, particularly in the U.S. healthcare market, and support the ongoing development of new features and clinical applications.
2025-05
Brainreader, Inc. Press Release
New Study Highlights Diagnostic Power of Neuroreader in Alzheimer's
A study published in BMC Neurology demonstrates the accuracy of Neuroreader, Brainreader's software, in differentiating neurocognitive disorders like traumatic brain injury, early-onset Alzheimer's, late-onset Alzheimer's, and behavioral variant frontotemporal dementia through distinct patterns of volume loss. The study analyzed MRI scans from 137 participants, showing that Neuroreader's AI-enabled software can quickly and accurately identify brain atrophy patterns often not visible through traditional visual assessments.
2024-09
Cision News
BRAINREADER A/S, DENMARK - PRESS RELEASE - PR NEWSWIRE U.S.
Brainreader Inc. is in advanced negotiations to provide its Neuroreaderu00ae software as the sole source of volumetric brain analytics for Dr. Lee Hood's Phenome Health, a one-million-person, ten-year trial focused on dementia and brain health. This collaboration aims to revolutionize data, science, and clinical practice related to dementia treatment and understanding worldwide.
2022-11
Imaging Technology News
Infinitt North America Announces Collaboration with Brainreader A/S to Market Neuro AI for Brain Structure Analysis
Infinitt North America and Brainreader A/S have partnered to expand the use of Brainreader's FDA-cleared Neuroreader software, which analyzes MRI sequences to identify and quantify abnormal brain structures in under ten minutes. This collaboration aims to improve diagnostic speed, accuracy, and depth of understanding for clinicians.
2022-06
Brainreader
Brainreader Partners with Aalborg University to Advance AI Neuroimaging
Brainreader has entered a three-year research and development partnership with Aalborg University to advance AI in neurodegenerative disease research. The collaboration will support a PhD project focused on using AI and deep learning to understand disease progression in conditions like Alzheimer's and Multiple Sclerosis.
2021-07
accessdata.fda.gov
Brainreader ApS February 4, 2015 C/O Mette Munch QA Consultant Skagenvej 21 Egaa, 8250 DENMARK Re: K140828 Trade/Device Name
The FDA determined that Brainreader's NeuroreaderTM Medical Image Processing Software is substantially equivalent to a legally marketed device, allowing it to be marketed in the United States. This software automates the manual process of identifying, labeling, and quantifying brain structures on MR images.
2015-02

Frequently Asked Questions

Brainreader's flagship product is Neuroreaderu00ae, an FDA-cleared and CE-marked AI-enabled software that performs quantitative brain volumetric analysis from routine MRI scans. It quantifies up to 83 brain structures, providing objective data and identifying subtle atrophy patterns that aid in the earlier detection and monitoring of neurodegenerative diseases like Alzheimer's and other dementias.
For Alzheimer's disease, Neuroreaderu00ae helps identify progressive hippocampal and temporal lobe atrophy, a classic hallmark of the disease. In cases of Traumatic Brain Injury (TBI), it provides objective volumetric measurements, left-right asymmetry indices, and standardized segmentation to highlight subtle structural changes often missed by visual inspection. While the provided information doesn't detail specific epilepsy detection mechanisms for Neuroreaderu00ae, it is mentioned as a condition where brain volume changes are key indicators, and the software can help identify these changes.
Neuroreaderu00ae is FDA-cleared (Class II) and CE-marked, and Brainreader is ISO 13485 certified and HIPAA compliant. All personal health information (PHI) processed by Neuroreaderu00ae is handled securely in accordance with HIPAA requirements, and data can be anonymized prior to upload or routed via a mediation server.
Neuroreaderu00ae is designed for seamless integration into routine MRI protocols. It processes standard 3D T1-weighted MRI sequences from 1.5T or 3.0T scanners, with images securely uploaded or routed via PACS integration. The software then automatically segments and quantifies brain structures, generating a comprehensive report typically in under 10 minutes.
Brainreader provides guided onboarding, including user training, product instructions, and workflow support to ensure proper implementation and use of Neuroreaderu00ae. They also offer customer support via phone and email for sales, support, and general inquiries.
Brainreader, founded in 2011, is a Series A company that has raised $14.6M in funding. They have established strategic partnerships with companies like INFINITT North America to integrate Neuroreaderu00ae into PACS systems, and Blackford Analysis to bring advanced medical image analysis to healthcare professionals. They are also in advanced negotiations with Phenome Health for a large-scale brain health trial.
While specific pricing details are not publicly available in the provided information, Neuroreaderu00ae is sold as a software service on a per-use or subscription basis. In the U.S., the adoption of CPT codes for brain volumetry is creating new reimbursement pathways, and Neuroreaderu00ae is applicable for the recently issued, reimbursable CPT III codes 0865T and 0866T for longitudinal brain quantitative MRI analysis.

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