Products

Us2.v2
Eko.ai Pte. Ltd d/b/a Us2.ai
Cardiology AI
Us2.ai is an FDA-cleared, AI-powered tool that automates echocardiogram interpretation, delivering a complete structured echo report with measurements, disease detection, and clinical findings, making heart risk detection more accurate, consistent, and accessible worldwide.
Us2.v1
eko.ai Pte. Ltd. d/b/a Us2.ai
Cardiology AI
Us2.ai provides FDA-cleared, fully automated AI software for echocardiography analysis, generating comprehensive structured reports with measurements and disease detection in seconds, significantly improving workflow efficiency and diagnostic accuracy.

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About eko.ai Pte. Ltd. d/b/a Us2.ai

Us2.ai (formerly eko.ai Pte. Ltd.) is a Singapore-based healthcare AI company dedicated to transforming cardiovascular diagnostics through fully automated echocardiography analysis. Their FDA-cleared and CE-marked software platform, Us2.v1 and Us2.v2, leverages advanced machine learning and deep clinical expertise to process comprehensive echocardiographic studies, including 2D and Doppler images, from any vendor in less than two minutes. This technology delivers complete, structured echo reports with measurements, editable annotations, and conclusions for every heart chamber, significantly reducing reporting time and increasing daily scan throughput.

For physicians, Us2.ai offers a solution that goes beyond partial automation, providing zero-click analysis and eliminating measurement variability, while maintaining accuracy comparable to expert human sonographers. The platform supports the detection of various heart conditions, including cardiac amyloidosis, aortic stenosis, heart failure, and valvular disease, by combining AI pattern recognition with guideline-based measurements. This democratizes expert-level cardiac diagnostics, making echocardiography analysis faster, more accurate, and accessible, ultimately improving patient outcomes and expanding healthcare access globally.

Focus Areas

Echocardiography analysis AI in ultrasound imaging heart disease detection cardiovascular care cardiac amyloidosis heart failure pulmonary hypertension aortic stenosis strain imaging

Business Intelligence

Key InvestorsIHH Healthcare, Heal Partners, Peak XV Partners (formerly Sequoia India), EDBI, Pappas Capital, Partech Ventures, SGInnovate, Bfa Global Investors, East Post Road Ventures, FJ Labs
PartnershipsAstraZeneca (research), Janssen (research), Duke University, Fujifilm, deepc, Harrison.ai, Merative Merge, Brigham & Women's Hospital, INFINITT North America, Lenus Health
TechnologyDeep learning solutions, AI-powered, cloud-native, integrates with ultrasound devices and PACS, automated pattern recognition, guideline-based measurements, DICOM processing, real-time analysis
FDA Clearances3 cleared products (estimated)

What Physicians Need to Know

Echocardiography Analysis
Us2.ai provides fully automated analysis of all heart chambers using both 2D and Doppler views, generating comprehensive measurements and structured reports.
AI in Ultrasound Imaging
The company leverages advanced AI, including deep learning solutions and pattern recognition algorithms, to offer decision support for echocardiogram interpretation.
Heart Disease Detection
Us2.ai's technology facilitates the detection of a wide array of heart-related conditions, including heart failure (with preserved ejection fraction), pulmonary hypertension, aortic stenosis, and cardiac amyloidosis.
Cardiovascular Care Enhancement
Their solutions are designed to improve clinical outcomes, enhance efficiency, accuracy, and streamline workflows in echocardiography for higher quality cardiac care.
Cardiac Amyloidosis Detection
A key specialization is the AI-based pattern recognition model for detecting cardiac amyloidosis from a single apical four-chamber view, a capability that is FDA-cleared and CE-marked.
Strain Imaging
The platform includes automated Global Longitudinal Strain (GLS) and regional strain analysis, supporting nuanced diagnosis of heart failure and coronary artery disease.
Key Differentiators
Us2.ai stands out with 100% AI automation, eliminating manual frame selection and annotation, and delivering complete structured echo reports rather than single measurements. It is FDA-cleared and CE Marked, offers explainable AI with editable outputs, and is vendor-agnostic, working with any ultrasound manufacturer (GE, Philips, Siemens, handheld POCUS).
Technology Stack
The core technology relies on machine learning and deep learning, utilizing pattern recognition algorithms. It supports flexible deployment options (cloud or on-premise) and integrates seamlessly with standard healthcare IT systems via DICOM routing, HL7, and DICOM SR.
Physician Tip

For physicians, Us2.ai offers significant time savings by reducing reporting time by up to 70% and increasing daily scan throughput, thereby freeing up valuable time for patient interaction and complex cases. The platform ensures improved accuracy and consistency through standardized, reproducible measurements, reducing inter-observer and intra-observer variability. It enhances clinical decision-making with guideline-directed, structured reporting, editable AI outputs, and disease-specific indications. The automation reduces workload and fatigue for sonographers and cardiologists by eliminating tedious manual tasks. Importantly, physicians retain final clinical authority with editable AI-generated drafts. The system also supports population health initiatives and screening by enabling efficient disease detection and follow-up, helping to lower patient backlogs.

Us2.ai is designed for seamless integration into existing hospital infrastructure and workflows. It connects to any ultrasound device, PACS, CVIS, or EMR via standard DICOM routing (ports 104/11112) and supports HL7 and DICOM SR for structured reports. Deployment can be cloud-based or on-premise, with minimal IT effort and no permanent infrastructure changes. Partnerships with companies like Merative (Merge Cardio), ASCEND Cardiovascular, and Aidoc (aiOS) further enhance its integration capabilities within broader cardiovascular imaging and AI platforms.

Products by eko.ai Pte. Ltd. d/b/a Us2.ai

2 products in the directory

Us2.v2
Eko.ai Pte. Ltd d/b/a Us2.ai
Cardiology AI
Us2.ai is an FDA-cleared, AI-powered tool that automates echocardiogram interpretation, delivering a complete structured echo report with measurements, disease detection, and clinical findings, making heart risk detection more accurate, consistent, and accessible worldwide.
Us2.v1
eko.ai Pte. Ltd. d/b/a Us2.ai
Cardiology AI
Us2.ai provides FDA-cleared, fully automated AI software for echocardiography analysis, generating comprehensive structured reports with measurements and disease detection in seconds, significantly improving workflow efficiency and diagnostic accuracy.

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Press & Coverage

Us2.ai
Canon Medical Systems USA and Us2.ai Announce Reseller Relationship for AI-Enabled Echocardiography
Canon Medical Systems USA and Us2.ai have partnered, allowing Canon to offer Us2.ai's cloud-based AI echocardiography software alongside its Aplio i-series ultrasound systems. This collaboration aims to broaden the availability of Us2.ai's software through Canon's sales channel.
2026-07
Us2.ai (Circulation: Cardiovascular Imaging)
Integrating Clinical Data with AI Echocardiography for Improved Cardiac Amyloidosis Detection
This international multicenter study, published in Circulation: Cardiovascular Imaging, demonstrates that integrating clinical and laboratory data with the FDA-cleared Us2.Ca deep learning model significantly improves cardiac amyloidosis detection, achieving 93% sensitivity and 90% accuracy.
2026-06
Us2.ai (International Journal of Cardiology)
AI Echo for Post-AMI Risk Stratification: Predicting Outcomes After A Heart Attack
Published in the International Journal of Cardiology, this study of 1,001 AMI patients shows that combining AI-derived echocardiographic parameters with traditional clinical risk factors significantly improves prediction of one-year mortality and major adverse cardiac events.
2026-06
Us2.ai
How Us2.ai and Merge Are Bringing AI Echo Directly Into Clinical Workflows
Representatives from Us2.ai and Merge discussed their new integration on the Cardiac Wire Show, which embeds Us2.ai's AI directly into the Merge platform to streamline clinical workflows for echo technicians and cardiologists.
2026-04
Us2.ai
Us2.ai receives FDA clearance for Us2.v2, transforming cardiovascular ultrasound analysis
Us2.ai announced FDA clearance for Us2.v2, featuring 45 automated echo parameters, including strain analysis, marking a significant advancement in medical innovation for cardiovascular ultrasound analysis.
2024-04
FUJIFILM Healthcare Americas Corporation
Fujifilm Partners with Us2.ai to Provide AI-Automated Echocardiography Analysis for Cardiologists and Sonographers Across the Nation
FUJIFILM Healthcare Americas Corporation and Us2.ai have partnered to integrate Us2.ai's AI-driven echocardiography analysis software with Fujifilm's LISENDO 800 cardiovascular ultrasound system, aiming to automate analysis and reporting of echocardiograms.
2025-03
Us2.ai
Us2.ai Secures US$15M Series A To Improve AI Detection of Cardiovascular Disease
Us2.ai, a Singapore-based medtech firm, raised US$15 million in a Series A funding round led by IHH Healthcare and Heal Partners, with participation from other investors, to accelerate its global commercial and regulatory rollout of AI software for echocardiography.
2022-04
Us2.ai
Us2.ai receives CE mark for the latest version of its AI echo software
Us2.ai announced that its latest version of fully automated echocardiography software has received CE Mark clearance, expanding its clinical deployment across Europe and offering comprehensive, guideline-directed echo analysis.
2025-06

Frequently Asked Questions

Us2.ai provides an FDA-cleared, fully automated AI software that processes echocardiograms in real-time, delivering comprehensive, structured reports with zero clicks. It integrates with existing ultrasound devices and PACS systems, offering vendor-agnostic analysis of 2D and Doppler images.
Us2.ai's platform offers automated detection for a wide range of heart conditions, including cardiac amyloidosis, heart failure (HFpEF, HFrEF, HFmrEF), pulmonary hypertension, and aortic stenosis. It combines deep learning pattern recognition with guideline-based measurements to identify these diseases, even enabling population-level screening for conditions like cardiac amyloidosis.
Us2.ai's software is FDA-cleared and CE-marked, with regulatory approvals in over 19 countries globally. The company also holds SOC 2 Type II and BSI certifications, ensuring high standards for data security and operational integrity.
Yes, Us2.ai provides validated global longitudinal strain analysis for patients, including those with and without atrial fibrillation, along with regional strain validated in real-world datasets. The solution is designed for seamless integration into existing infrastructure, connecting with PACS, CVIS, and EMR systems without disrupting current workflows.
Us2.ai operates on a volume-based pricing model, with specific installation and associated costs varying by configuration, requiring direct contact for a formal quotation. The company offers support for implementation and inquiries via email and phone, typically responding within 1-2 business days.
Us2.ai has established strategic partnerships with key players in healthcare technology, including deepc, Fujifilm, Merative (Merge Cardio), ConcertAI's TeraRecon, and Aidoc. These collaborations aim to integrate Us2.ai's AI-driven echocardiography analysis into broader clinical AI platforms and imaging systems, enhancing workflow efficiency and diagnostic capabilities for healthcare providers.
Founded in 2017, Us2.ai is a fast-growing medtech startup that has secured significant funding, including a US$15 million Series A round in April 2022, contributing to a total funding of over $19 million across multiple rounds. The company is actively expanding its clinical implementation globally and is recognized for its pioneering role in AI for cardiovascular care.

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