Products

Icobrain
Icometrix NV
Neurology AI
Icobrain is an AI-powered software by Icometrix NV that analyzes brain MRI and CT scans to provide quantitative insights for neurological conditions such as multiple sclerosis, dementia, Alzheimer's, stroke, epilepsy, and traumatic brain injury. It is FDA-cleared and CE-marked, assisting clinicians in diagnosis, monitoring, and treatment assessment.
icobrain-ctp
Icometrix NV
Neurology AI
Icometrix icobrain-ctp is an AI-powered image processing software for CT perfusion scans of the brain, providing analysis and communication of dynamic imaging datasets to quantify tissue flow and blood volume parameters.
icobrain aria
icometrix NV
Neurology AI
icobrain aria is an AI-powered software by icometrix for automated detection, measurement, and severity assessment of Amyloid-Related Imaging Abnormalities (ARIA) on brain MRI scans, crucial for monitoring Alzheimer's patients on amyloid-targeting therapies.

See all 3 products →

About icometrix NV

icometrix NV is a leading healthcare AI company specializing in advanced software solutions for the quantitative analysis of brain MRI and CT scans. Their flagship platform, icobrain, provides physicians with objective and clinically meaningful data to support the diagnosis, monitoring, and treatment of a wide range of neurological disorders. This includes conditions such as Multiple Sclerosis (MS), dementia (including Alzheimer’s disease), traumatic brain injury (TBI), epilepsy, stroke, and Parkinson’s disease. The AI-powered tools quantify subtle changes in brain structures, lesion load, and atrophy over time, offering critical insights that complement traditional radiological readings and enhance data-driven clinical decision-making.

For medical professionals, icometrix’s solutions are designed to integrate seamlessly into existing workflows, providing FDA-cleared and CE-marked reports. Notable products include icobrain ms for visualizing changes in multiple sclerosis and icobrain aria, the first FDA-cleared AI solution for detecting and quantifying amyloid-related imaging abnormalities (ARIA), which are crucial for monitoring patients on amyloid-targeting therapies for Alzheimer’s. Beyond neuroimaging, icometrix also developed icolung for AI-driven lung analyses during the COVID-19 pandemic and icompanion, a digital platform for MS patients to track their health. The company’s technology is utilized in hundreds of hospitals globally and is also a partner for pharmaceutical companies in clinical trials and drug development.

Focus Areas

AI-powered brain imaging analysis neurological disorders Multiple Sclerosis Alzheimer's disease dementia amyloid-related imaging abnormalities (ARIA) stroke traumatic brain injury epilepsy Parkinson's disease brain tumors quantitative MRI/CT analysis digital health platform patient monitoring

Business Intelligence

Key InvestorsCapricorn Partners, KU Leuven, UZA, Forestay Capital, Optum Ventures, HERAN Partners
PartnershipsGE HealthCare (acquisition), American College of Radiology (ACR), DENT Neurologic Institute, Philips, Siemens Healthineers, Nuance, Micron, Guerbet, DocPanel, Aidoc, Affidea, AstraZeneca, VITO, Barco
AcquisitionsAcquired by GE HealthCare (September 12, 2025)
TechnologyCloud-based AI solution, deep-learning-based AI algorithms, icobrain platform, icobridge for secure data transfer and interoperability with PACS and EMR systems. Utilizes technologies such as Kubernetes, MySQL, and TypeScript.
FDA ClearancesMultiple. Key clearances include initial FDA clearance for icobrain in 2015-2016, and icobrain aria, the first and only AI software approved for detecting, measuring, and grading amyloid-related imaging abnormalities (ARIA) in November 2024. cleared products (estimated)

What Physicians Need to Know

Specialized AI-Powered Brain Imaging Analysis
icometrix NV specializes in AI-powered quantitative MRI and CT analysis for a wide range of neurological disorders, including Multiple Sclerosis, Alzheimer's disease, dementia, amyloid-related imaging abnormalities (ARIA), stroke, traumatic brain injury, epilepsy, Parkinson's disease, and brain tumors.
FDA-Cleared and CE-Marked Solutions
Their flagship product, icobrain aria, is the first AI Computer-Aided Detection and Diagnosis FDA 510(k) cleared solution for detecting and quantifying amyloid-related imaging abnormalities (ARIA-E and ARIA-H), a critical side effect of new Alzheimer's therapies.
Quantitative Longitudinal Monitoring
The icobrain platform offers tools to accurately visualize and quantify lesion and brain volume changes over time, which is crucial for timely diagnoses and life-changing therapeutic decisions in conditions like Multiple Sclerosis and dementia.
Digital Health Platform for Patient Engagement
icompanion, their smartphone app, enables patients to track relevant health information, including patient-reported outcomes, objective cognitive tests, and passive monitoring, fostering better self-management and communication with care teams.
Robust Technology Stack
icometrix leverages a cloud-based AI/ML analysis pipeline, primarily powered by Amazon Web Services (AWS), utilizing services like Amazon EKS, Amazon EC2 Auto Scaling, and Amazon S3 for scalable, cost-effective, and secure processing of large imaging datasets.
Strategic Industry Integrations
Recently acquired by GE HealthCare, icometrix's solutions are being integrated with GE HealthCare's MRI systems for seamless workflow. They also have partnerships with companies like Philips to integrate their AI-powered software into MRI scanners and healthcare informatics platforms.
Physician Tip

For physicians, icometrix NV stands out by transforming complex brain imaging scans into clear, actionable, and quantitative insights, enabling data-driven clinical decision-making. Their AI solutions significantly improve diagnostic sensitivity and accuracy, particularly in detecting subtle changes and critical abnormalities like ARIA, while reducing subjective manual analysis and processing time. The FDA-cleared status of solutions like icobrain aria provides confidence in their clinical utility, especially for monitoring patients on new amyloid-targeting therapies. Furthermore, the integration with major imaging vendors ensures a streamlined workflow, and the icompanion app facilitates enhanced patient monitoring and engagement, ultimately supporting personalized and efficient neurological care. The company also provides evidence of cost-effectiveness and supports reimbursement efforts, such as CPT III code reimbursement in the US.

icometrix NV's solutions are designed for seamless integration into existing clinical workflows. Their platform is being integrated with GE HealthCare's MRI systems and deep learning offerings (e.g., AIR xu2122 Brain, AIR Recon DL, SONIC DL 3D) for optimized workflows. They also integrate with Philips' BlueSeal MR scanners and healthcare informatics platform, including Philips cloud-based AI Manager, to provide an end-to-end solution for acquiring, reading, and reporting MRI brain scans. This multi-vendor compatibility ensures broad accessibility and ease of adoption within diverse healthcare environments.

Products by icometrix NV

3 products in the directory

Icobrain
Icometrix NV
Neurology AI
Icobrain is an AI-powered software by Icometrix NV that analyzes brain MRI and CT scans to provide quantitative insights for neurological conditions such as multiple sclerosis, dementia, Alzheimer's, stroke, epilepsy, and traumatic brain injury. It is FDA-cleared and CE-marked, assisting clinicians in diagnosis, monitoring, and treatment assessment.
icobrain-ctp
Icometrix NV
Neurology AI
Icometrix icobrain-ctp is an AI-powered image processing software for CT perfusion scans of the brain, providing analysis and communication of dynamic imaging datasets to quantify tissue flow and blood volume parameters.
icobrain aria
icometrix NV
Neurology AI
icobrain aria is an AI-powered software by icometrix for automated detection, measurement, and severity assessment of Amyloid-Related Imaging Abnormalities (ARIA) on brain MRI scans, crucial for monitoring Alzheimer's patients on amyloid-targeting therapies.

What the Web Says

Icometrix NV is a Belgian MedTech company specializing in AI-powered brain MRI analysis and neurological disease quantification. Their flagship product, icobrain, provides automated quantitative analysis of brain scans for conditions like multiple sclerosis, Alzheimer's disease, and traumatic brain injury. The company is recognized for its strong technical expertise, industry specialization in neurological imaging, and regulatory clearances (FDA and CE marking) for its platform.

Overall: Positive

Strengths

  • Exceptional technical expertise in deep learning applied to medical imaging.
  • High industry specialization in neurological imaging.
  • Regulatory clearances (FDA and CE) provide confidence for hospital procurement and clinical adoption.
  • Demonstrated real-world scalability and reliability with 200+ hospital deployments.
  • Academic pedigree ensures innovation grounded in peer-reviewed research.
  • AI-driven, validated, and FDA-cleared solutions assist radiologists and neurologists with comparing and quantifying brain MRI scans over time.

Limitations

  • Narrow vertical focus, which may not suit organizations looking for a broader medical AI partner.
  • Premium pricing structure, potentially a barrier for smaller clinics and regional healthcare providers.

Based on reviews from: SectorPunk, Elion, Icometrix (company website), Philips and icometrix (press release)

Last updated: 2026-07-18

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Press & Coverage

BioSpace
icometrix is proud to announce the market approval of icobrain aria, the first market-approved solution for monitoring amyloid-related imaging abnormalities (ARIA) in Alzheimer's disease
icometrix announced market approval for icobrain aria, an AI-based solution for monitoring Amyloid-Related Imaging Abnormalities (ARIA) in Alzheimer's disease, which are potential side effects of new Alzheimer's therapies. This solution aims to improve radiological reading performance and diagnostic accuracy.
2024-09
Icometrix
The first AI-driven MRI solution for safer Alzheimer's treatment
icometrix received FDA clearance for icobrain aria on November 7th, 2024, making it the first and only AI software approved for detecting, measuring, and grading ARIA, a side effect of new amyloid-targeting Alzheimer's therapies. This clearance is expected to enhance the safety and accessibility of these treatments.
2025-05
GE HealthCare
GE HealthCare announces intent to acquire icometrix to strengthen neurology portfolio with brain MRI assessment solutions
GE HealthCare announced its agreement to acquire icometrix, aiming to strengthen its neurology portfolio with AI-powered brain imaging analysis for neurological disorders like Alzheimer's disease. The acquisition will integrate icometrix's icobrain platform, including icobrain aria, with GE HealthCare's MRI systems.
2025-09
MedTech Dive
GE HealthCare inks Icometrix buyout to acquire brain MRI software
GE HealthCare's acquisition of icometrix, for an undisclosed sum, includes AI-powered software for detecting side effects of Alzheimer's drugs. icometrix's software, which received its initial 510(k) clearance in 2016, also offers modules for other neurological disorders.
2025-09
Philips
Philips and icometrix advance precision diagnosis in neurology with innovative AI-based imaging solutions at #RSNA24
Philips and icometrix partnered to deploy an AI-driven, end-to-end solution for MRI brain scans, optimizing diagnosis and treatment monitoring for neurological conditions such as Alzheimer's and multiple sclerosis. This integration was unveiled at RSNA 2024.
2024-11
Icometrix
From rigorous validation to reimbursement
This article highlights the extensive scientific validation and health-economic studies undertaken by icometrix for its icobrain software, emphasizing its accuracy and utility in managing Alzheimer's disease and multiple sclerosis. It underscores the importance of robust evidence for clinical adoption and reimbursement.
2025-07
Radiology: Artificial Intelligence
Automated Volumetric Software in Dementia: Help or Hindrance to the Neuroradiologist?
This research article investigates the impact of automated volumetric software, including icometrix's technology, on diagnostic accuracy for dementia. The study found that the use of icometrix reports improved diagnostic accuracy in Alzheimer's disease cases.
2024-11
Journal of Alzheimer's Disease
Diagnostic performance of automated MRI volumetry by icobrain dm for Alzheimer's disease in a clinical setting: a REMEMBER study
This study evaluates the diagnostic value of icobrain dm for Alzheimer's disease in routine clinical practice, comparing it to FreeSurfer software. The findings indicate improved diagnostic accuracy for differentiating between AD stages with icobrain dm.
2021-XX

Frequently Asked Questions

icometrix NV is a company that provides AI-powered brain imaging analysis to assist in the diagnosis and management of neurological disorders. Their icobrain platform extracts quantitative data from brain MRI and CT scans, transforming complex images into clear, actionable insights for clinicians. This AI-driven approach helps shift from subjective visual assessment to a data-driven evaluation of brain volume loss, lesions, and other abnormalities.
icometrix's technology supports a wide range of neurological disorders, including Multiple Sclerosis, Alzheimer's disease, dementia, amyloid-related imaging abnormalities (ARIA), stroke, traumatic brain injury, epilepsy, Parkinson's disease, and brain tumors. For MS, it visualizes lesion and brain volume changes over time, while for Alzheimer's and dementia, it aids in differential diagnosis and monitoring of atrophy. Specifically, icobrain aria is FDA-cleared for detecting, measuring, and grading ARIA (edema/sulcal effusion and hemorrhage/superficial siderosis), which are side effects of amyloid-targeting therapies.
The core of icometrix's offerings is the icobrain platform, which includes disease-specific AI solutions like icobrain ms, icobrain dm, icobrain aria, icobrain cva, icobrain tbi, icobrain ep, and icobrain tumor. Beyond imaging analysis, icometrix also offers icompanion, a digital platform and mobile app designed to help people with MS and their care teams monitor clinical symptoms and treatments efficiently between visits.
icometrix's icobrain software solutions are FDA-cleared and CE-marked, indicating compliance with regulatory standards in the U.S. and Europe. For instance, icobrain aria is the first AI software approved by the FDA for detecting and grading ARIA. The company's commitment to data privacy and security is also a key aspect of its operations.
icometrix solutions are designed for seamless integration into standard clinical workflows, delivering reports and perfusion maps directly into PACS and email inboxes. The cloud-based nature of some solutions, like icobrain cva, facilitates this integration. icometrix also collaborates with healthcare providers and pharmaceutical companies on clinical trials and real-world evidence studies, suggesting comprehensive support for implementation and utilization.
While specific pricing models are not publicly detailed, icometrix has secured a CPT Category III code for quantitative brain MRI analysis software, which is a significant step towards reimbursement for its services. This CPT code is the first of its kind for brain imaging, indicating a pathway for healthcare providers to seek reimbursement for using icometrix's AI solutions.
icometrix has established partnerships with organizations like Aidoc for stroke care and has received grants from The Michael J. Fox Foundation for Parkinson's research. A significant development is the announced intent of GE HealthCare to acquire icometrix, which aligns with GE HealthCare's precision care strategy in neurology. This acquisition is expected to strengthen GE HealthCare's neurology portfolio by integrating icometrix's AI-powered insights with their advanced imaging technologies, ensuring icometrix's continued stability and expanded reach.

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