icobrain-ctp
Overview
icobrain-ctp, developed by Icometrix NV, is an AI-powered image processing software package designed for trained professionals, including physicians and medical technicians. It is used for the analysis and communication of computed tomography (CT) perfusion scans of the brain. The software runs on a standard ‘off-the-shelf’ computer or a virtual platform like VMware.
It provides capabilities for dynamic imaging datasets acquired with CT Perfusion imaging protocols, including the calculation of parameters related to tissue flow (perfusion) and tissue blood volume. Specific computed parameter maps include Cerebral Blood Flow (CBF), Cerebral Blood Volume (CBV), Mean Transit Time (MTT), and Tissue residue function time to peak (TMax). Data and images are acquired through DICOM-compliant imaging devices, and results, including CT perfusion parameter maps, are exported in standard DICOM format for viewing on existing radiological imaging viewers.
icobrain-ctp is part of the broader icobrain platform, which offers AI solutions for various neurological disorders by extracting clinically meaningful data from both MRI and CT scans. The platform aims to assist radiologists and neurologists in diagnosing neurological conditions, monitoring progression, and improving outcomes efficiently and objectively.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- Image processing, analysis, and communication of CT perfusion scans
- Calculation of Cerebral Blood Flow (CBF), Cerebral Blood Volume (CBV), Mean Transit Time (MTT), and Tissue residue function time to peak (TMax)
- DICOM-compliant data acquisition and export
- Runs on standard off-the-shelf computers or virtual platforms (e.g., VMware)
- Automated quantitative reports
- Color-coded segmentations for highlighting key findings
- Pre-populated radiological reporting templates
- Seamless integration with PACS and EMR systems (via icobridge)
- AI-powered analysis for neurological disorders
- Longitudinal monitoring of brain changes
Use Cases
- Diagnosis and monitoring of stroke through CT perfusion analysis
- Assessment of acute impacts of brain trauma, including midline shift and hyperdensity volumes
- Supporting differential diagnosis and monitoring of atrophy in dementia and Alzheimer's disease
- Accurate visualization of lesion and brain volume changes over time in multiple sclerosis
- Detecting, measuring, and grading Amyloid-Related Imaging Abnormalities (ARIA)
- Supporting differential diagnosis of epilepsy through abnormality patterns
What Physicians Need to Know
Leverage icobrain-ctp for rapid, objective, and quantitative assessment of CT perfusion parameters in acute ischemic stroke cases. The automated analysis of core and penumbra volumes, along with CBF, CBV, MTT, and TMax maps, provides crucial data to support timely treatment decisions, especially within expanded thrombectomy windows. Integrate these insights with non-contrast CT and CT angiography findings for a comprehensive stroke evaluation. The standardized reports can enhance consistency and reduce inter-reader variability.
icobrain-ctp is designed for seamless integration into existing clinical workflows. It acquires data from DICOM-compliant imaging devices and exports processed results, including perfusion parameter maps, in standard DICOM format for viewing on existing radiological imaging viewers. The cloud-based solution delivers reports and perfusion maps directly to Picture Archiving and Communication Systems (PACS) and e-mail inboxes. Icometrix also utilizes 'icobridge' to connect MRI scanners, PACS, and Electronic Medical Record (EMR) systems, facilitating secure data transfer and automated report generation.
Details
| Category | Neurology AI, Radiology & Imaging AI |
| Pricing | Not publicly disclosed. — Not publicly disclosed. |
| Deployment | Software-as-a-service (SaaS) deployed on standard computers or virtual platforms (e.g., VMware), integrating with hospital PACS and EMR systems. |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status |
1 AI-estimated icobrain-ctp received FDA 510(k) clearance on February 28, 2020, under K192962. It is classified as a Class II medical device (21 CFR 892.2050 - Picture archiving and communications system) and is intended for image processing, analysis, and communication of computed tomography (CT) perfusion scans of the brain. |
| Integrations | |
| EHR | Not specified |
| Specialties | Neurology, Neurosurgery, Radiology |
What the Web Says
Icobrain-ctp is an AI-powered software designed to analyze CT perfusion scans of the brain, providing quantitative data for various neurological conditions. It aims to automate and standardize the interpretation of brain imaging, assisting physicians in diagnosing, monitoring disease progression, and assessing treatment response for conditions like stroke, traumatic brain injury, multiple sclerosis, and dementia. The software has received FDA clearance and CE marking, and new CPT-III codes for icobrain's quantitative brain MRI analysis became active in January 2024, facilitating reimbursement from over 30 insurers in the U.S.
Overall: PositiveStrengths
- Automates and standardizes brain image analysis, reducing subjective interpretation and inter-center variation.
- Provides objective quantitative data on brain volumes, lesions, and perfusion, aiding in earlier and more accurate diagnosis and monitoring of neurological conditions.
- Enhances collaboration between radiologists and neurologists by providing comprehensive and standardized reports.
- Can help predict disease progression and optimize treatment strategies, particularly in conditions like multiple sclerosis.
- FDA-cleared and CE-marked, with established CPT-III codes for reimbursement, indicating regulatory approval and increasing accessibility.
- Demonstrated to improve sensitivity and detection for Amyloid-Related Imaging Abnormalities (ARIA) in Alzheimer's treatments, enhancing patient safety.
Limitations
- Real-time collection and analysis of evidence for broad clinical adoption/implementation is still ongoing for icobrain ct.
- One Reddit user reported that their insurance did not cover the icobrain scan, costing an additional $75.
- Some institutions may have site licenses that do not cover scans performed elsewhere, limiting its use with external imaging data.
- The results of icobrain mr cross and icobrain mr long, two distinct image processing pipelines for MRI, cannot be compared with each other.
- Limited independent reviews from healthcare IT, tech reviewers, G2, and Capterra were found.
- One Reddit user did not find the icobrain scan to provide meaningful data, though this was an isolated comment.
Based on reviews from: icometrix.com, Moberg Analytics, YouTube, accessdata.fda.gov, X-ray Interpreter, Health AI Register, Elion, Reddit, RAYUS Radiology
Last updated: 2026-07-18
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