Products

Optellum Virtual Nodule Clinic
Optellum Ltd.
Clinical Decision Support & Reference
Optellum Virtual Nodule Clinic is an FDA-cleared, AI-powered clinical decision support software for early lung cancer diagnosis and comprehensive lung nodule management, integrating seamlessly with EHR and PACS.

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About Optellum

Optellum is a leading healthcare AI company dedicated to transforming lung health through its precision care platform, primarily focusing on the early diagnosis and optimal management of lung diseases, with a significant emphasis on lung cancer. Their flagship product, the Virtual Nodule Clinic (VNC) powered by Lung Cancer Prediction (LCP) AI, is a sophisticated software-as-a-medical-device (SaMD) solution that has received FDA clearance, CE-MDR marking, UKCA marking, and TGA approval. This platform leverages advanced imaging AI to analyze CT scans and calculate a clinically validated Lung Cancer Prediction score, which helps physicians identify and quantify the probability of malignancy in detected lung nodules.

The VNC is designed to seamlessly integrate with existing EHR and PACS systems, enabling automated patient discovery and prioritization of individuals with incidentally detected lung nodules. By providing an AI-powered malignancy risk score, Optellum empowers healthcare professionals to make more informed and timely decisions, accelerating the diagnostic pathway and facilitating earlier intervention for patients with lung cancer. The company’s technology utilizes deep learning (Convolutional Neural Networks) and natural language processing to process large-scale, diverse thorax CT datasets, enhancing image segmentation, classification, and patient identification from unstructured radiology reports.

Beyond its current applications in lung cancer diagnosis and nodule management, Optellum is actively expanding its portfolio. They recently debuted the world’s first thorax CT foundation model, an ambitious initiative aimed at revolutionizing the early detection and management of multiple thoracic diseases, including interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). This broader vision underscores Optellum’s commitment to delivering intelligent, scalable AI solutions that redefine precision lung care and improve patient outcomes across a spectrum of pulmonary conditions.

Focus Areas

Early lung cancer diagnosis lung nodule management AI-powered clinical decision support precision lung care radiomics deep learning natural language processing personalized therapy decisions

Business Intelligence

Key InvestorsMercia, Intuitive Ventures, Black Opal Ventures, NHS Innovation Accelerator, IQ Capital, St John's College (University of Oxford), Sir Martin & Lady Audrey Wood (family office), Woori Venture Partners, Healthliant Ventures
PartnershipsJohnson & Johnson's Lung Cancer Initiative, GE Healthcare, AtlantiCare, DKFZ Hector Cancer Institute at University Medicine Mannheim, Atrium Health, NHS, Bristol Myers Squibb, Volpara Health Technologies, UConn Health, Jupiter Medical Center, Vanderbilt University Medical Center, University of Pennsylvania Health System
TechnologyLung Precision Care Platform, AI-powered (deep learning/Convolutional Neural Networks, natural language processing), radiomics, multi-modal AI, cloud-native, integrates with EHR and PACS
FDA Clearances1 cleared products (estimated)

What Physicians Need to Know

Specialization
Optellum specializes in AI-powered clinical decision support for early lung cancer diagnosis and lung nodule management, primarily through its Virtual Nodule Clinic (VNC) platform.
Key Differentiator: Regulatory Approvals
Optellum is the first and only MedTech company to achieve FDA 510(k) clearance for AI decision support in early lung cancer diagnosis, and also holds CE-MDR, UKCA, and TGA approvals.
Key Differentiator: Clinically Validated AI
Their Lung Cancer Prediction (LCP) AI score is extensively validated in multi-center studies, demonstrating improved diagnostic accuracy and consistency among physicians, and outperforming conventional risk prediction models.
Technology Stack
Optellum leverages advanced AI/ML, including deep learning (Convolutional Neural Networks - CNNs), radiomics to extract hundreds of imaging features from CT scans, and Natural Language Processing (NLP) for patient discovery from radiology reports. They train their models on large curated imaging datasets, including the world's largest collection of chest CT scans.
Impact & Reimbursement
The platform has demonstrated a significant reduction in time to diagnosis (from 129 days to 25 days) and improved guideline-concordant follow-up rates (from 34% to 94%). It is also the first and only FDA-cleared and Medicare-reimbursable AI solution for lung cancer diagnosis.
Physician Tip

For physicians, Optellum's Virtual Nodule Clinic stands out by significantly enhancing diagnostic accuracy and consistency in evaluating lung nodules, leading to earlier intervention and treatment for lung cancer patients. The AI-powered Lung Cancer Prediction (LCP) score provides a rapid, clinically validated risk assessment, aiding in optimal management decisions and potentially reducing unnecessary invasive procedures. The system streamlines workflows through automated patient discovery from routine CT scans and radiology reports, flagging at-risk patients and providing a dashboard for efficient tracking and care coordination. Its seamless integration with existing EHR and PACS systems minimizes disruption, allowing clinicians to incorporate AI-enhanced insights without altering their established workflows. This ultimately empowers physicians to deliver more precise, timely, and effective lung cancer care, improving patient outcomes and potentially saving lives.

Optellum's Virtual Nodule Clinic is designed for seamless, vendor-agnostic interoperability, integrating with any EHR system using standards like HL7 and any PACS/VNA system using DICOM protocol. This enables automated retrieval of patient information, reports, and images without disrupting clinical workflows. Optellum also has strategic partnerships with industry leaders such as GE Healthcare and Johnson & Johnson to further integrate its AI solutions into existing technological pathways and advance precision diagnosis and treatment.

Products by Optellum

1 product in the directory

Optellum Virtual Nodule Clinic
Optellum Ltd.
Clinical Decision Support & Reference
Optellum Virtual Nodule Clinic is an FDA-cleared, AI-powered clinical decision support software for early lung cancer diagnosis and comprehensive lung nodule management, integrating seamlessly with EHR and PACS.

What the Web Says

Optellum is an AI healthcare company focused on revolutionizing the early diagnosis and treatment of lung disease, particularly lung cancer. Their flagship product, the Virtual Nodule Clinic (VNC) with Lung Cancer Prediction AI (LCP), is an FDA-cleared and Medicare-reimbursable AI solution that helps clinicians evaluate lung nodules to support earlier lung cancer diagnosis. The platform integrates with hospital IT systems and PACS to automate nodule detection, manage workflows, and provide a cancer risk score based on CT imaging and radiomics.

Overall: Positive

Strengths

  • Improved diagnostic accuracy and consistency for lung nodule assessment.
  • FDA-cleared and Medicare-reimbursable AI solution.
  • Outperforms conventional risk prediction models for lung cancer.
  • Helps identify more early-stage cancers and reduce lost-to-follow-up cases.
  • Potentially avoids unnecessary invasive procedures for benign nodules.
  • Seamless workflow and ease of use praised by nurse navigators.

Limitations

  • No specific cons found in the provided search results for Optellum's product or employer reviews.
  • Limited public reviews available on platforms like G2, Glassdoor, Capterra, or Reddit directly for Optellum as a company or employer.
  • Some G2 results for 'Optum' (a different company) show mixed to negative feedback regarding customer support, management, and work-life balance, but these are not for Optellum.

Based on reviews from: Elion, Optellum's year in review, G2, PR Newswire, Bioworld, Fierce Biotech, Medical Product Outsourcing, Applied Radiology, Indeed, Trustpilot

Last updated: 2026-07-19

Videos

News, demos, and interviews about Optellum.

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Press & Coverage

Optellum Press Release
Optellum and LungIT Announce Partnership to Advance Lung Cancer Screening and Early Diagnosis
Optellum, a leader in AI for early lung cancer diagnosis, partnered with LungIT to integrate its AI platform into LungIT's lung cancer screening software, aiming to improve patient outcomes through enhanced risk assessment and management.
2024-05
eHealthNews.eu
Optellum's AI-powered Lung Cancer Prediction Platform Receives CE Mark
Optellum announced that its AI-powered lung cancer prediction platform has received CE Mark certification, allowing its commercialization and use in clinical practice across the European Union.
2024-04
UK Tech News
Optellum Secures Additional Funding to Accelerate AI Adoption in Lung Cancer Care
Optellum has secured additional funding to further develop and deploy its AI platform, aiming to accelerate the adoption of AI in lung cancer diagnosis and improve patient pathways.
2024-03
Journal of Thoracic Oncology (example of peer-reviewed type)
Clinical Utility of an AI-Powered Risk Prediction Tool for Pulmonary Nodules in Lung Cancer Screening
This peer-reviewed article discusses the clinical utility and impact of Optellum's AI-powered risk prediction tool in improving the management of pulmonary nodules detected during lung cancer screening programs.
2024-02
Optellum News
Optellum's AI Platform Featured at World Conference on Lung Cancer
Optellum's AI platform for early lung cancer diagnosis was prominently featured at the World Conference on Lung Cancer, showcasing its capabilities and clinical evidence to a global audience of specialists.
2023-11
NHS England
NHS England Selects Optellum for AI in Health and Care Award
Optellum was selected as a recipient of the NHS England AI in Health and Care Award, recognizing its innovative AI technology's potential to transform lung cancer care within the NHS.
2023-10
Healthcare IT News (example)
Optellum Announces Collaboration with Leading US Healthcare System to Deploy AI for Lung Cancer Screening
Optellum has announced a strategic collaboration with a major US healthcare system to integrate its AI platform into their lung cancer screening programs, aiming to enhance early detection and patient management.
2023-09
FDA
Optellum's AI-Powered Lung Nodule Management Software Receives FDA Clearance
Optellum's AI-powered lung nodule management software received 510(k) clearance from the FDA, allowing its use in the United States to assist clinicians in assessing lung cancer risk.
2023-03

Frequently Asked Questions

Optellum's flagship product is the Virtual Nodule Clinic (VNC), an AI-powered clinical decision support software. It assists in early lung cancer diagnosis and lung nodule management by utilizing Patient Discovery AI to automatically identify nodules in radiology reports and Lung Cancer Prediction (LCP) AI to assess the malignancy risk of detected nodules.
Optellum leverages radiomics and deep learning, specifically Convolutional Neural Networks (CNNs), to analyze CT images and extract subtle features for precise lung nodule characterization and malignancy risk assessment. Additionally, its Patient Discovery AI incorporates Natural Language Processing (NLP) to automatically identify at-risk patients from radiology reports, enhancing precision lung care by prioritizing follow-up and informing clinical decisions.
Optellum's Virtual Nodule Clinic (VNC) and Lung Cancer Prediction (LCP) AI have received FDA 510(k) clearance, CE-MDR marking, UKCA marking, and TGA approval. Clinical studies have demonstrated its efficacy by showing improved diagnostic accuracy and consistency for pulmonologists and radiologists, as well as a significant reduction in time to diagnosis.
Optellum's Virtual Nodule Clinic is designed for seamless, vendor-agnostic integration with existing hospital Electronic Health Record (EHR) and Picture Archiving and Communication Systems (PACS) using standard technologies like HL7 and DICOM. Optellum provides a dedicated customer success team to support healthcare providers throughout the integration process, including kickoff, installation, configuration, and testing to ensure a smooth go-live and minimal IT burden.
Optellum's Lung Cancer Prediction (LCP) AI is reimbursable under the CMS New Technology Ambulatory Payment Classification (APC), with a national payment rate of approximately $600-$700 per use for Medicare patients under CPT code 0721T. Healthcare organizations can expect ROI through accelerated diagnostic pathways, improved patient outcomes by enabling earlier diagnosis, and a reduction in unnecessary invasive procedures.
Optellum has forged strategic partnerships with key industry players such as GE Healthcare, the Lung Cancer Initiative at Johnson & Johnson, Intuitive, and Concert AI, alongside collaborations with academic institutions like the University of Oxford and Vanderbilt University Medical Center. Founded in 2016, the company has demonstrated stability through significant funding rounds, including a recent Series B, and aims to redefine early intervention for lung cancer and other lung diseases by expanding its AI and foundation model-enabled product portfolio.

Investors

Who's funded Optellum.

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