Products

Paige
Paige
Oncology AI
Paige is an AI-first digital pathology platform with FDA-cleared applications for accelerating and augmenting cancer diagnosis from whole-slide images, used by pathologists for result interpretation.

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About Paige

Paige is a pioneering healthcare AI company that has revolutionized cancer diagnostics and treatment through advanced computational pathology. Founded on the principle of leveraging artificial intelligence to address critical issues in oncology, Paige developed a cloud-based platform and AI applications designed to enhance pathologists’ workflow, increase diagnostic confidence, and improve patient outcomes globally. Their technology, built from an extensive dataset of digitized pathology slides, clinical reports, and genomic data, provides deep insights into the molecular and cellular complexities of cancer, enabling more precise detection, subtyping, grading, and biomarker identification across various cancer types, including prostate, breast, and gastrointestinal cancers.

Prior to its acquisition, Paige was recognized for its innovative AI-powered solutions, including the first FDA-cleared AI application in pathology. The company’s offerings, such as the Paige Prostate Suite, Paige Breast Suite, and Paige GI Suite, assist pathologists in identifying disease presence, assessing severity, and guiding treatment decisions. Paige also focused on developing foundation models and AI modules to accelerate research and development for novel computational pathology applications and to support pharmaceutical companies in biomarker discovery and personalized treatment evaluation.

In August 2025, Paige was acquired by Tempus AI, integrating its cutting-edge AI technology, extensive dataset of nearly 7 million digitized pathology slides, and foundational AI models into Tempus’s ecosystem to further advance cancer care.

Focus Areas

Cancer diagnostics digital pathology AI-powered solutions computational pathology biomarker discovery precision oncology prostate cancer breast cancer GI cancer pan-cancer detection foundation models

Business Intelligence

Key InvestorsCasdin Capital, Johnson & Johnson Innovation – JJDC, Inc., Goldman Sachs Asset Management, Healthcare Venture Partners, Breyer Capital, Julian Robertson, KKR, Catalio Capital Management, AI Venture Labs
PartnershipsMicrosoft, Leica Biosystems, OptraSCAN, Hamamatsu, PathPresenter, Burjeel Holdings, Breast International Group (BIG), Lumea, Indica Labs, Aiforia, Quest Diagnostics, Philips
AcquisitionsAcquired by Tempus AI for $81.25M in August 2025
TechnologyCloud-based platform, AI-powered solutions, deep learning algorithms, foundation models (Virchow, PRISM2), multi-modal AI models (combining vision and language), utilizes Microsoft Azure
FDA Clearances2 cleared products (estimated)

What Physicians Need to Know

Cancer Diagnostics & Digital Pathology
Paige offers AI-assisted diagnostic applications for detecting, subtyping, grading, and quantifying cancer across a wide range of tissue types, including prostate, breast, and gastrointestinal (GI) cancers, as well as pan-cancer detection across 40+ types. Their solutions are designed to support diagnostic decision-making and optimize pathology workflows.
AI-powered Solutions & Computational Pathology
Leveraging advanced AI and deep learning, Paige develops computational pathology solutions that go beyond basic detection. This includes AI applications for biomarker discovery, prognosis (e.g., Minimal Residual Disease, Residual Cancer Burden), and predicting treatment response. They are pioneers in applying foundation models to cancer care.
Biomarker Discovery & Precision Oncology
Paige's novel AI technologies can reveal multiple molecular biomarkers directly from standard tissue samples (H&E slides), such as detecting over 1,600 biomarkers with OmniScreenu2122. This capability is crucial for advancing precision oncology by enabling targeted therapeutic selection and optimizing clinical trial design.
Foundation Models
Paige has developed industry-leading foundation models like Virchow (Vision AI) and PRISM (Multi-Modal AI, combining Large Vision Models and Large Language Models). These models are trained on massive, diverse datasets of millions of digitized pathology slides, clinical reports, and genomic data, enabling pan-cancer detection and accelerating AI development.
Pan-Cancer Detection
Their foundation models are capable of detecting cancer across more than 40 different tissue types, including common, complex, and rare tumor entities, setting a new standard in AI-based cancer diagnosis.
Physician Tip

For physicians, Paige's AI solutions offer significant advancements in cancer diagnostics. Expect improved diagnostic accuracy and efficiency, as AI applications assist in detecting subtle complexities of cancer, potentially reducing diagnostic errors and turnaround times. The AI acts as a 'second set of eyes,' allowing pathologists to focus on challenging cases and alleviate workload pressures. The ability to uncover molecular biomarkers directly from H&E slides facilitates more precise and personalized treatment planning. Furthermore, Paige's FDA-cleared solutions provide a high level of clinical validation and trust. The platform is designed to integrate seamlessly into existing digital pathology workflows, minimizing disruption and maximizing the benefits of AI-powered insights. The Paige Albau2122 co-pilot can further streamline your workflow with intuitive voice and text commands, enhancing the overall diagnostic process.

Paige's platform is built for interoperability, offering advanced integration capabilities. Its flexible architecture, powered by a set of APIs, allows for vendor-neutral integrations with diverse whole-slide image (WSI) scanners, Laboratory Information Systems (LIS), and both Paige's own AI solutions and third-party AI applications. This open approach ensures that labs and pathologists can connect their existing and future digital pathology applications into a single, managed environment, fostering customized workflows and avoiding vendor lock-in.

Products by Paige

1 product in the directory

Paige
Paige
Oncology AI
Paige is an AI-first digital pathology platform with FDA-cleared applications for accelerating and augmenting cancer diagnosis from whole-slide images, used by pathologists for result interpretation.

What the Web Says

Paige.ai operates in two distinct areas: AI-powered local SEO for businesses (often referred to as Paige by Merchynt) and AI-assisted diagnostics for cancer pathology (Paige AI). The local SEO tool is highly praised for its ease of use, automation, and effectiveness in improving Google Business Profile rankings and local search visibility. The healthcare-focused Paige AI is recognized as a solid medical tool, being the first company with FDA approval for AI-driven cancer diagnosis in pathology. Employer reviews for Paige (the healthcare AI company) indicate a positive work environment with strong leadership and good work-life balance.

Overall: Positive

Strengths

  • Exceptional ease of use and intuitive features for local SEO.
  • Strong automation capabilities for Google Business Profile management and reporting.
  • Excellent and responsive customer support, including direct CEO involvement.
  • Effective in improving Google Business Profile rankings and local SEO.
  • FDA-approved AI for cancer diagnosis in pathology, improving detection rates.
  • Positive employer ratings for work-life balance, leadership, and culture.

Limitations

  • Editing limitations, such as inability to specify detailed requests for post rewrites.
  • Challenging learning curve for some users, particularly with initial setup.
  • Product can be considered pricey for some users ($99 per client).
  • Desire for more guided tutorials for non-tech-savvy individuals.
  • Video creation process can be clunky with script and image mismatches.
  • Narrow focus on prostate cancer limits the addressable market for the healthcare AI.

Based on reviews from: G2, AI is Everywhere, Capterra, Wellfound, Elion, FeaturedCustomers, Reddit, Indeed.com, Built In NYC, AHRQ

Last updated: 2026-07-22

Videos

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Press & Coverage

Tempus AI
Tempus Announces the Acquisition of Paige
Tempus AI acquired Paige for $81.25 million, primarily in common stock, to expand its dataset, technical team, and digital pathology footprint. The acquisition includes Paige's dataset of nearly 7 million digitized pathology slides and a foundation AI model trained on over 2.3 million whole-slide images.
2025-08
Paige.ai
U.S. FDA Grants Paige Breakthrough Device Designation for AI Application that Detects Cancer Across Different Anatomic Sites
Paige received Breakthrough Device designation from the FDA for Paige PanCancer Detect, an AI-assisted diagnostic application designed to detect suspicious cancer foci across multiple tissues and organs. This is the first such designation for an AI tool capable of identifying common and rare cancer variants from different anatomic sites.
2025-04
Paige.ai
Paige Launches New System-Wide AI Application for the Gastrointestinal Tract
Paige launched a new system-wide AI application for the gastrointestinal tract, expanding its portfolio of AI-powered tools for cancer detection and classification. This application supports pathologists in identifying benign and malignant conditions across the entire GI tract.
2025-03
Paige.ai
Paige Adds to Regulatory Portfolio with New FDA Clearance
Paige's FullFocusu2122 digital pathology image viewer received FDA 510(k) clearance for use with the Leica Aperio GT 450 DX and Hamamatsu NanoZoomer S360MD Slide scanners, expanding its compatibility with major hardware vendors. This clearance reinforces Paige's commitment to clinically validated solutions.
2025-01
Paige.ai
Major Study Published in Nature Medicine on Paige's Virchow the First Demonstration of Clinical-Grade Performance for Cancer Detection Using a Foundation Model
Paige, in collaboration with Microsoft, published a study in Nature Medicine highlighting Virchow, the first million-slide foundation model for cancer, demonstrating clinical-grade performance across 16 cancer types. Virchow's extensive dataset enables advanced capabilities and accuracy for novel cancer diagnosis applications.
2024-07
Paige.ai
Artificial Intelligence Helps Pathologists Increase Diagnostic Accuracy and Efficiency in the Detection of Breast Cancer Lymph Node Metastases
A study published in The American Journal of Surgical Pathology demonstrated that Paige Breast Lymph Node AI can help pathologists reduce reading times by more than half and improve detection rates for breast cancer lymph node metastases. Two of three pathologists showed significant sensitivity improvements from 74.5% to 93.5% with AI assistance.
2024-07
Paige.ai
Paige Collaborates with Microsoft to Transform Cancer Diagnosis and Treatment with the Use of Pathology AI
Paige announced a collaboration with Microsoft to apply AI to digital pathology images for developing new clinical applications and computational biomarkers to transform cancer diagnosis and patient care. Microsoft also made a strategic investment in Paige to accelerate the development and deployment of AI diagnostics.
2023-01
AI Business
AI-based pathology startup Paige raises $70 million for fight against cancer
Paige closed its Series B fundraising at $70 million, including an additional $15 million from Goldman Sachs Merchant Banking division, bringing the total capital raised to over $95 million. The funding aims to accelerate Paige's mission of transforming pathology workflows in cancer and developing custom diagnostic and clinical trial solutions.
2020-07

Frequently Asked Questions

Paige provides a range of AI-powered digital pathology products, including the Paige Prostate Suite for prostate cancer detection, grading, and perineural invasion, and the Paige Breast Suite for breast cancer identification and classification, including lymph node metastasis and HER2 expression analysis. Additionally, they offer the Paige GI Suite for gastrointestinal conditions and Paige PanCancer Detect, an application capable of identifying suspicious regions for cancer across over 40 different tissue types, encompassing both common and rare cancers.
Paige's AI solutions, particularly their foundation models like Virchow and PRISM, are trained on extensive datasets of digitized pathology slides and clinical reports, enabling a deep understanding of cancer morphology and multi-modal analysis. These models facilitate the development of advanced applications for precise cancer detection, subtyping, and the identification of molecular biomarkers directly from tissue samples, thereby accelerating advancements in precision oncology and drug discovery.
Paige has achieved significant regulatory milestones, notably receiving the first-ever FDA De Novo marketing authorization for an AI-based software in pathology with Paige Prostate Detect in 2021. Their products also hold multiple FDA Breakthrough Designations, CE-IVDD Marks, and UKCA Marks, underscoring their commitment to stringent regulatory standards for clinical use. The Paige FullFocus digital pathology image viewer is FDA-cleared for primary diagnosis with various scanners, further demonstrating their compliance.
The Paige Platform is designed for flexible integration with existing laboratory information systems (LIS) and diverse whole-slide imaging (WSI) scanners, promoting seamless digital pathology workflows. They offer open, secure, and scalable API capabilities to enable custom workflows and access to both Paige and third-party AI applications, supported by robust data management and cloud storage solutions, often leveraging Microsoft Azure. Paige also provides dedicated AI support and services teams to assist partners in leveraging their technology effectively.
While specific pricing details are not publicly disclosed, Paige aims to offer flexible deployment options that can reduce upfront investment for healthcare institutions adopting digital pathology. Beyond direct product sales, Paige also licenses its advanced Foundation Models and AI modules to other AI developers, organizations, and life sciences companies, enabling them to develop their own AI models for research, clinical trials, and commercial purposes.
Paige offers both specialized AI solutions for specific cancer types and broader pan-cancer detection capabilities. While they have dedicated suites for prostate, breast, and GI cancers, their Paige PanCancer Detect application is designed to identify suspicious regions for cancer across more than 40 different tissue types. This pan-cancer solution, built on foundation models like Virchow, demonstrates strong analytical precision in detecting both common and rare cancers.
Paige has formed strategic partnerships with technology leaders like Microsoft, utilizing Microsoft Azure for cloud infrastructure and collaborating on foundation model development to enhance AI in pathology. They also collaborate with digital pathology providers such as Gestalt and scanner manufacturers like Philips, Leica, and Hamamatsu to ensure broad compatibility and integration. Positioned as a leader in AI-powered digital pathology with continuous expansion of its AI portfolio and regulatory clearances, Paige demonstrates a strong and stable future outlook in revolutionizing cancer care.

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