Products

Deep Lens
Paradigm Health
Drug Discovery & Research
Paradigm Health's AI-powered cloud platform integrates patient data from EMRs, labs, and genomics to automate clinical trial matching for oncology patients, directly assisting physicians and accelerating research.

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About Paradigm Health

Paradigm Health is a healthcare technology company dedicated to transforming the clinical research ecosystem. Their mission is to create equitable access to clinical trials for all patients, integrating research seamlessly into routine care. The company achieves this by developing and deploying an AI-powered platform designed to enhance trial efficiency and significantly reduce the operational burdens on healthcare providers. This platform leverages advanced AI to automate patient matching, optimize site feasibility, and streamline trial data collection and delivery, thereby accelerating the identification and enrollment of suitable patients for clinical studies.

For physicians, Paradigm Health’s solutions aim to democratize access to cutting-edge therapies by enabling community healthcare organizations to participate in a broader range of clinical trials with fewer resources. The platform integrates with existing health systems, allowing for more precise alignment between patients and trials by utilizing electronic medical records and genomic data. This approach not only expands patient access to potentially life-saving treatments, particularly in underserved areas, but also helps ensure that trial populations are more representative of the diverse patient demographics the therapies are intended to serve. Paradigm Health operates the largest oncology research network in the United States and has demonstrated success in increasing patient enrollment and improving screening accuracy.

Focus Areas

AI-powered clinical trial platform clinical trial recruitment patient identification digital pathology oncology research precision medicine EHR integration real-world evidence generation decentralized clinical trials

Business Intelligence

Key InvestorsARCH Venture Partners, General Catalyst, F-Prime Capital, GV, LUX Capital, Mubadala Capital, DFJ Growth, American Cancer Society's BrightEdge Fund, JobsOhio Ventures
PartnershipsParexel, Southern Oncology Specialists (via Deep Lens), Webby Hills Cancer Center (via Deep Lens), Hematology/Oncology Associates of Central New York (via Deep Lens), Norton Healthcare (via Deep Lens), Lantern Pharma (via Deep Lens), Precision for Medicine (via Deep Lens)
AcquisitionsDeep Lens (acquired early 2023), Flatiron Health's Clinical Research Business
TechnologyAI-powered clinical trial infrastructure, cloud-native, EHR-integrated technology, Deep Learning, Natural Language Processing, workflow and collaboration tools, eSource Casebook, SPIRE (Scalable Platform for Integrated Research & Evidence), Deep Lens VIPER platform (AI-based image detection, telepathology, integrates EMR and molecular data feeds)

What Physicians Need to Know

AI-Powered Clinical Trial Platform
Paradigm Health (formerly Deep Lens) offers VIPER, an AI-driven cloud platform that revolutionizes clinical trial screening and enrollment, particularly in oncology.
Accelerated Clinical Trial Recruitment
The platform focuses on significantly faster recruitment of cancer patients by identifying eligible individuals at the time of diagnosis, streamlining the enrollment process.
Precision Patient Identification
VIPER automates patient identification by integrating and analyzing lab, Electronic Medical Record (EMR), and genomic data, ensuring accurate matching to relevant trials.
Advanced Digital Pathology
The platform leverages AI with advanced pathology workflows, enabling pathologists to diagnose cancer more swiftly and accurately, and to connect patients with appropriate clinical trials.
Oncology Research Specialization
Paradigm Health's solutions are specifically tailored for oncology clinical trials, supporting cancer drug development and research within community oncology practices.
Precision Medicine Integration
The AI platform integrates cancer genetic data to rapidly match patients to precision therapies and oncology clinical trials based on their unique genetic profiles.
Real-World Evidence (RWE) Generation
Through its 'Real Time Feasibility' offering, the platform combines EMR, lab, and genomic data to provide real-time insights into patient populations, contributing to RWE generation.
Decentralized Clinical Trial Enablement
By facilitating remote patient identification and accelerating recruitment within community oncology settings, Paradigm Health supports the principles and efficiencies of decentralized clinical trials.
Physician Tip

For physicians, Paradigm Health's platform, VIPER, offers a transformative approach to clinical trial participation. It significantly reduces the administrative burden by automating patient screening and matching to appropriate trials at the point of diagnosis, freeing up valuable time. This enables earlier access for patients to potentially life-changing precision therapies and expands the range of clinical trial options available within your practice. The service is provided at no cost to oncology practices, making it an accessible tool to enhance patient care and contribute to cutting-edge research. Furthermore, it fosters peer-to-peer collaboration and keeps patients connected to advanced clinical research.

Paradigm Health's VIPER platform boasts robust integration capabilities. It directly integrates with major Electronic Medical Record (EMR) systems, including Epic, OncoEMR, and iKnowMed. The platform also seamlessly incorporates molecular data feeds from leading genetic testing companies such as Caris Life Sciences, Foundation Medicine, Guardant Health, Tempus, Myriad Genetics, and NeoGenomics, as well as in-house lab and pathology feeds. Additionally, it offers built-in APIs to facilitate integration with various hardware, software vendors, and biopharmaceutical companies.

Products by Paradigm Health

1 product in the directory

Deep Lens
Paradigm Health
Drug Discovery & Research
Paradigm Health's AI-powered cloud platform integrates patient data from EMRs, labs, and genomics to automate clinical trial matching for oncology patients, directly assisting physicians and accelerating research.

What the Web Says

Paradigm Health appears to be a company with several distinct entities, including a clinical trial platform, a dental software provider, a quality management software provider, a managed care company for workers' compensation, and various healthcare and home health providers. Reviews are mixed, with some entities receiving high praise for their products and employee culture, while others face criticism regarding management, work environment, and patient care. There are also mentions of Paradigm Treatment Centers, which have received some negative feedback on Reddit related to the troubled teen industry.

Overall: Mixed

Strengths

  • Paradigm (Medical Billing/RCM) is praised for streamlining administrative tasks, easy setup, and efficient billing and RCM services for home care agencies.
  • Paradigm (Dental Software) is noted for its ease of use, useful features, and good customer support.
  • Paradigm 3 (Quality Management Software) is liked for consolidating critical aspects of a Quality System into one program and excellent customer support.
  • Paradigm Health (various healthcare providers) often receives positive employee reviews for work-life balance, supportive culture, and caring for patients and employees.
  • Paradigm Corp (specialty care management) is recognized as a 'Great Place to Work' with a positive, inclusive, and supportive employee-centric culture.
  • Paradigm Health (clinical trial platform) is focused on re-engineering clinical trials around patient care, accelerating enrollment, and improving data quality.

Limitations

  • Some users of Paradigm (Medical Billing/RCM) reported an inability to deactivate clients in the portal and a lack of notification when a client is not being billed.
  • Paradigm (Dental Software) has been criticized for excessive use of the tab key in billing and occasional issues with chart documentation not saving or notes being lost.
  • Paradigm 3 (Quality Management Software) has a training module that was not effective for capturing recertification training information.
  • Paradigm Healthcare (various healthcare providers) has received negative employee reviews citing a challenging and often hostile work environment, lack of support, and high turnover.
  • Paradigm Treatment Centers on Reddit have some reviews reminiscent of tactics used by 'Troubled Teen Industry' programs, with some former patients reporting negative experiences.
  • Paradigm Oral Health (corporate dental) has been criticized by employees for lack of raises, minimal bonuses, and negative changes due to corporate rules and regulations.

Based on reviews from: G2, Reddit, Capterra, Indeed.com, Great Place To Work, Paradigm Health Website

Last updated: 2026-07-22

Videos

News, demos, and interviews about Paradigm Health.

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Press & Coverage

PR Newswire
Paradigm Health Raises $78 Million Series B to Make Clinical Trials Part of Routine Care Across the U.S. and Globally
Paradigm Health secured an oversubscribed $78 million Series B funding round, led by ARCH Venture Partners, to expand its AI-powered platform and integrate clinical trials into routine care across the U.S. and globally.
2025-12
The Pharma Letter
Paradigm Health secures funding and acquires Flatiron's clinical research business
Paradigm Health raised $78 million in Series B funding and acquired Flatiron Health's oncology-focused Clinical Research Business, expanding its network to include over 25 academic medical centers and nearly 100 local oncology practices.
2025-12
Fierce Biotech
Clinical trials tech startup Paradigm raises $78M, acquires part of Roche's Flatiron
Paradigm Health closed a $78 million Series B round and acquired Flatiron Health's clinical research business, aiming to improve patient access to clinical trials and accelerate drug development.
2025-12
PR Newswire
Paradigm Health Announces Collaboration with the FDA to Transform Regulatory Review of Clinical Trial Data
Paradigm Health launched a research collaboration with the FDA to accelerate clinical trial execution and regulatory review using its technology-enabled Study Conduct platform for real-time data analysis.
2026-04
PR Newswire
Paradigm Health Launches SPIRE to Accelerate Late-Phase Clinical Evidence Generation
Paradigm Health introduced SPIRE, a new platform for post-approval and late-stage clinical studies, designed to generate prospective clinical evidence faster and with greater real-world representativeness.
2026-04
PR Newswire
New Peer-Reviewed Research Demonstrates Effectiveness of Paradigm Health Study Conduct Products
New peer-reviewed research highlights the feasibility and effectiveness of Paradigm Health's EHR-integrated eSource platform for late-stage clinical research in community oncology settings.
2026-04
Paradigm Health
Paradigm Health Submits Response to FDA's Real-Time Clinical Trials Initiative RFI, Informed by Biopharma Sponsors and Providers
Paradigm Health submitted its response to the FDA's Request for Information on the Real-Time Clinical Trial Initiative, drawing insights from its AI-enabled infrastructure and discussions with biopharma sponsors.
2026-06
Paradigm Health
Clinical Trial Matching with AI and Large Language Models
This article discusses how Paradigm Health's AI-native matching solution, combining structured data prefilters with Large Language Models, improves the accuracy and timeliness of patient-trial matching.
2025-10

Frequently Asked Questions

Paradigm Health utilizes an AI-powered platform that integrates directly with provider systems to continuously evaluate structured and unstructured clinical data against trial eligibility criteria. This enables precise patient identification and accelerates recruitment by surfacing likely candidates within clinical workflows, reducing manual screening efforts.
Paradigm Health has a significant focus on oncology research, particularly in community and rural settings, aiming to democratize access to trials and improve patient representation. While not explicitly detailing 'digital pathology,' their AI-native approach to clinical trial matching and data analysis supports precision medicine by optimizing protocol development to reflect actual care patterns.
Paradigm Health's platform seamlessly integrates with Electronic Health Records (EHRs) to capture and transfer data directly from patient visits, minimizing manual entry and improving data quality. This EHR-integrated data capture is crucial for generating high-quality real-world evidence, especially for late-phase and post-approval studies, as demonstrated by their SPIRE platform.
Paradigm Health is actively working to embed research directly into routine care across a network of community and academic sites, addressing the 'zip code problem' and expanding access to diverse patient populations. Their technology-enabled model supports pragmatic study designs and reduces administrative burden, facilitating decentralized trial execution and making research a more viable care option.
Key offerings include an AI-powered clinical trial matching and recruitment solution, and eSource Casebook for automated data capture and EHR-to-EDC data transfer. They also recently launched SPIRE, a platform specifically designed for accelerating late-phase and post-market clinical evidence generation.
Paradigm Health is committed to robust data security and privacy, holding SOC 2/Type 2 compliance attestation and HIPAA security compliance attestation. They have a formal Governance Committee and a comprehensive Data Privacy Program to ensure adherence to applicable laws and regulations.
Paradigm Health has strategic partnerships with organizations like Parexel and Fujitsu, and recently acquired Flatiron Health's Clinical Research Business, significantly expanding its oncology research network. The company is backed by leading healthcare and life sciences investors, including ARCH Venture Partners, indicating strong financial backing and a commitment to long-term growth.
While specific pricing details are not publicly disclosed, Paradigm Health's model is typically solution-based, tailored to the needs of sponsors and providers for their clinical trial initiatives. They offer comprehensive support, including full-service study conduct support and dedicated recruitment coordinators, to streamline trial operations and reduce burden on research teams.

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