PNOĒ

Malden, MA, United States  All United States companies → — Founded 2016
Healthcare Analytics / BI Specialty-Focused AI Wearables / RPM
Cardiology Pulmonology Sports Medicine
Endocrinology & Metabolic AI Lab & Diagnostics
Venture Capital-Backed
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Products

PNOĒ
PNOĒ
Endocrinology & Metabolic AI
PNOĒ is a science-backed cardiometabolic analyzer that performs comprehensive breath-based assessments to measure 23 biomarkers, including VO₂ max, resting metabolic rate (RMR), fat burn efficiency, and biological age. It delivers a 360° snapshot of an individual's physiology by analyzing how oxygen flows through the lungs, heart, and cells. The insights generated are used to personalize nutrition, exercise, and longevity plans.
Varies

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About PNOĒ

PNOĒ is a healthcare AI company that has developed a portable, clinical-grade metabolic analysis system. This system utilizes breath analysis (also known as metabolic testing or VO2max testing) to provide a comprehensive physiological assessment. The PNOĒ device measures oxygen consumption (VO2) and carbon dioxide production (VCO2) to evaluate 23 biomarkers related to metabolic rate, heart, lung, and cellular fitness. This allows healthcare professionals to gain insights into a patient’s resting metabolic rate (RMR), VO2 max, fat-to-carbohydrate burn ratio, breathing efficiency, and biological age.

The AI-driven platform integrates these breath analysis results with data from wearables, blood tests, and body scans to create a holistic health snapshot. Based on this data, PNOĒ generates personalized nutrition, exercise, breathwork, and bio-optimization programs. The company aims to make advanced metabolic testing accessible beyond traditional lab settings, enabling health professionals to offer science-backed bio-optimization and personalized wellness plans to their clients. PNOĒ’s technology has been independently validated by institutions such as Georgetown University, the VA in Maryland, and Rutgers University.

Focus Areas

cardio-metabolic analysis breath analysis personalized nutrition personalized exercise longevity disease prevention weight management sports performance biological age assessment AI-driven health programs

Business Intelligence

Technologycloud-connected, AI-driven platform, proprietary software package, portable metabolic analyzer device, integrates with wearables and other biometric data

What Physicians Need to Know

Cardio-Metabolic Analysis & Breath Analysis
PNOu0112 offers clinical-grade metabolic analysis through a non-invasive 8-10 minute breath test. It measures 23 clinically validated biomarkers, including VO2 Max, resting metabolic rate (RMR), fat vs. carbohydrate utilization, ventilatory thresholds, respiratory efficiency, recovery capacity, and biological age. This provides a comprehensive picture of heart, lung, cellular fitness, and overall metabolism.
Personalized Nutrition & Exercise
Based on the metabolic data, PNOu0112 automatically generates personalized nutrition, exercise, recovery, supplementation, and bio-optimization plans. These plans adapt to individual biometrics, goals, and behavior, including meal plans with smart swaps, grocery lists, structured workouts with progress tracking, and zone-based analysis.
Longevity & Disease Prevention
PNOu0112 provides insights into biological age and offers strategies for anti-aging and disease prevention. It's an effective tool for early detection of chronic diseases like heart disease, lung disease, metabolic disease, and type two diabetes. The platform helps in creating personalized wellness programs and supports preventative measures.
Weight Management
PNOu0112 removes guesswork from weight management by revealing how the body functions physiologically. It identifies exact fat-burning zones and metabolic rate, allowing for targeted plans that maximize fat loss while preserving muscle. It also provides accurate calorie and metabolism insights, which are often off by hundreds in generic calculators.
Sports Performance
For athletes, PNOu0112 provides personalized training and recovery plans based on measured VO2 max, fat-burning efficiency, and other metabolic insights. It helps in optimizing performance, endurance, and strength by tailoring recommendations to the body's unique biology.
AI-Driven Health Programs
PNOu0112 utilizes an AI-driven engine that merges breath analysis results with data from wearables, blood tests, and body scans to generate a full-body health snapshot. The AI-assisted recommendations help practitioners deliver meaningful outcomes and provide personalized advice.
Physician Tip

PNOu0112 offers physicians a reliable, non-invasive, and easy-to-use tool to quantify their impact on patients without extensive lab work. It provides clinical-grade metabolic insights, allowing for more accurate clinical decisions and personalized care. The platform acts as a lead generator for various services by linking a client's VO2 Max and biological data to their relevant needs, such as IV therapy, red light therapy, and hormone optimization. PNOu0112's AI-powered program builder helps generate personalized plans, saving practitioners time in interpreting results. It also offers client monitoring with compliance tracking and automated alerts, and AI consultations to explain results and recommend next steps.

PNOu0112 integrates with leading wearables like Apple Watch (via Apple Health), Garmin, WHOOP, Fitbit (via Google Fit or third-party sync app), and Oura Ring, creating a comprehensive view of health and performance by combining metabolic testing results with daily activity, heart rate, sleep, and recovery stats. It also integrates with EHR systems such as Elation, Tebra (Kareo), ModMed, and DrChrono, and can connect with InBody devices.

Products by PNOĒ

1 product in the directory

PNOĒ
PNOĒ
Endocrinology & Metabolic AI
PNOĒ is a science-backed cardiometabolic analyzer that performs comprehensive breath-based assessments to measure 23 biomarkers, including VO₂ max, resting metabolic rate (RMR), fat burn efficiency, and biological age. It delivers a 360° snapshot of an individual's physiology by analyzing how oxygen flows through the lungs, heart, and cells. The insights generated are used to personalize nutrition, exercise, and longevity plans.
Varies

What the Web Says

PNOu0112 offers a portable, medical-grade cardio-metabolic analyzer that provides detailed insights into an individual's metabolism, cellular function, heart and lung fitness, fat-burning efficiency, and biological age through breath analysis. The company's technology is used by individuals for personalized health and fitness optimization, and by businesses like gyms, clinics, and medical practices to offer advanced metabolic testing services to their clients. While many users praise the detailed data and actionable insights provided, some healthcare professionals have raised concerns about the accuracy of results for certain patient populations and the company's support for interpreting complex cases.

Overall: Mixed

Strengths

  • Provides comprehensive and personalized metabolic data, including VO2 Max, RMR, and fat vs. carb burn.
  • Offers actionable recommendations for nutrition, training, and recovery based on individual metabolic profiles.
  • Portable and easy-to-use device with quick setup and real-time data display via a smartphone app.
  • Considered a gold standard for determining accurate heart-rate training zones.
  • Valuable tool for businesses to optimize operations, enhance client engagement, and upsell services.
  • Strong test-retest reliability and high degree of agreement with traditional lab-based systems for key metabolic measures.

Limitations

  • Some users and healthcare professionals have reported concerns about the accuracy of results for certain individuals, particularly those with underlying health conditions or on medication.
  • The company's support for interpreting complex cases and providing raw data to clients has been questioned.
  • Initial setup process for businesses can take longer than expected.
  • The focus of the website seems to be on benefits for businesses selling the testing rather than direct consumer information.
  • Less emphasis on raw data control and independent analysis compared to some competitors.
  • Some reports of the unit being unreliable and failing during patient tests.

Based on reviews from: Reddit, Mypnoe.com, Apple App Store, SimpliFaster, Telluride Whole Health, BioPeak Health, YouTube, Capterra, PMC

Last updated: 2026-09-13

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Press & Coverage

PR Newswire
Lumati and PNOu0112 Forge Strategic Alliance to Pioneer The Future of Longevity With Personalized Wellness
Lumati and PNOu0112 announced a strategic partnership at the 2025 Biohacking Conference to combine PNOu0112's metabolic assessments with Lumati's therapeutic modalities for personalized wellness. This alliance aims to offer complementary services, leverage shared marketing channels, and pursue technological integration.
2025-05
PNOu0112 Blog
PNOu0112: Revolutionizing Preventive Health with Breath Analysis
PNOu0112 is revolutionizing preventive health by making clinical-grade breath analysis accessible to everyone, providing a comprehensive metabolic profile through a simple 8-minute test. This technology, based on VO2 Max testing, measures 23 key biomarkers to offer insights into overall health, fat-burning efficiency, and biological age.
2025-08
PubMed
Assessing the Validity and Reliability of the PNOEu00af for Measuring Cardiometabolic Outcomes During Walking Exercise
This study, published in May 2025, concluded that the PNOu0112 system is a valid and reliable measure of cardiometabolic outcomes and is comparable to the COSMED K5 system for measuring respiratory gaseous exchange during treadmill walking exercise.
2025-05
Swift Recovery
Metabolism Unleashed: How the PNOu0112 Test Changes Everything
Swift Recovery highlights the PNOu0112 Metabolic Test as a powerful tool for transforming health and performance by revealing how the body uses energy at rest, providing science-backed data to end guesswork in nutrition and exercise. The test offers insights into lung ventilation, efficiency, breathing coordination, heart rate variability, and parasympathetic nervous system activation.
2025-09
TopDoctor Magazine
PNOu0112: Breathing New Life into Your Well-being
PNOu0112 offers a groundbreaking, science-based system that provides a personalized wellness experience through a 10-minute breath test, unveiling 23 biomarkers related to metabolism, cellular function, brain health, posture, and biological age. It aims to transform wellness strategies for both practitioners and clients by integrating advanced technology with personalized care.
2024-02
PNOu0112 Blog
Unlock Your Peak Performance and Longevity Potential with PNOu0112
PNOu0112's breath analysis technology offers clinical precision for optimizing nutrition, exercise, and lifestyle choices, providing personalized programs for weight management, endurance enhancement, and longevity optimization. The test measures VO2 max, cellular health, and metabolic efficiency to detect early risk factors and guide proactive health steps.
2024-04
TopDoctor Magazine
Breath Analysis: How the Invention of PNOE Could Change Healthcare Forever
PNOu0112 is presented as a powerful tool for healthcare professionals to provide personalized wellness programs and quantify their impact on patients through an easy, reliable, and non-invasive breath analysis process. It helps identify biological limitations and provides biometric justification for various bio-optimization services.
2023-04
Frontiers in Sports and Active Living (via PMC)
Validity and Reliability of the New Portable Metabolic Analyzer PNOE
This peer-reviewed study, published in September 2019, concluded that the portable metabolic cart PNOu0112 can accurately determine respiratory gases over a wide range of exercise intensities in healthy individuals within a controlled laboratory setting. The study compared PNOu0112 with COSMED – Quark CPET, a validated stationary metabolic cart.
2019-09

Frequently Asked Questions

PNOu0112's breath analysis offers a comprehensive cardio-metabolic assessment by measuring oxygen consumption and carbon dioxide production, providing insights into resting metabolic rate, substrate utilization (fat vs. carbohydrate burning), and cardiorespiratory fitness. This data allows for the precise tailoring of nutrition and exercise prescriptions to optimize patient outcomes for conditions like obesity, type 2 diabetes, and cardiovascular disease.
PNOu0112's AI platform integrates breath analysis results with other patient data to generate highly personalized nutrition and exercise protocols. It considers individual metabolic profiles, fitness levels, and health goals to create dynamic plans that adapt over time, aiming to improve compliance and achieve specific outcomes in areas such as weight management, disease prevention, and sports performance.
PNOu0112 offers various pricing models, which may include upfront purchase of devices, subscription services for the AI platform, or per-test fees, depending on the scale and needs of the healthcare practice. They provide comprehensive support, including training for staff, ongoing technical assistance, and resources to help integrate the PNOu0112 system seamlessly into existing clinical workflows and patient management.
PNOu0112 enhances patient compliance through personalized, data-driven programs that are continuously adapted based on progress and feedback, making them more engaging and effective. The platform's focus on objective metabolic markers and measurable improvements in health parameters provides strong motivation, and PNOu0112 often cites studies and clinical data demonstrating the efficacy of its approach in promoting longevity and preventing chronic diseases.
PNOu0112 has established partnerships with various healthcare providers, wellness centers, and research institutions to expand its reach and validate its technology. The company demonstrates stability through continuous product development, expanding market presence, and a clear vision focused on leveraging AI and breath analysis to revolutionize personalized health, with ongoing efforts in research and development to enhance its offerings.
PNOu0112's technology contributes to biological age assessment by providing key metabolic and cardiorespiratory markers that are indicative of overall physiological health and aging. By optimizing these markers through personalized interventions, it aids in disease prevention and significantly enhances sports performance by improving metabolic efficiency, endurance, and recovery for athletes.

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