Ziosoft

Newark, CA, USA; Tokyo, Japan  All Japan companies → Founded 1998
Imaging AI Specialist
Cardiology Cardiothoracic Surgery Radiology
Radiology & Imaging AI Surgical AI
Acquired/Operating Subsidiary (Corporate Backed) — Unknown

Products

Ziostation2
Ziosoft
Radiology & Imaging AI
Ziostation2 is Ziosoft's advanced visualization and AI-enabled medical imaging platform, providing comprehensive 2D, 3D, and 4D analysis across multiple modalities and specialties for efficient and repeatable diagnostic and surgical planning outcomes.

See all 1 product →

About Ziosoft

Ziosoft is a recognized leader in functional visualization and analysis software, leveraging cutting-edge 3D/4D AI-based visualization and quantitative analysis to benefit physicians, patients, and healthcare specialists. Founded in 1998, the company provides vendor-neutral and multi-modality advanced visualization technology platforms that aim to enhance diagnostic confidence, support lower dose options, and enable precision in surgical and treatment planning. Their solutions address the challenges of vast image datasets produced by various digital imaging modalities, offering more accurate and efficient analysis beyond traditional 3D visualization.

The company’s flagship platforms, such as Ziostation2 Advanced Visualization and the newer Revoras platform, offer extensive suites of multi-modality and multi-specialty protocols for a broad range of clinical applications, including neurology, cardiology, and pulmonology. Ziosoft’s PhyZiodynamic 4D advanced processing platform provides a ‘real-time’ journey through the body non-invasively, supporting precise surgical and radiation therapy planning for various organ targets like the brain, lungs, and heart. Recent collaborations, such as with Olympus, have led to the launch of AI-powered clinical decision tools for surgical planning in liver, lung, and kidney procedures, transforming 2D CT/MRI images into interactive, AI-enhanced 3D models for pre-operative planning. The Revoras platform also incorporates AI functionality for automation, such as coronary calcium scoring, and features like Rembrandt mode for photorealistic image rendering, which can be valuable for education and patient engagement.

Focus Areas

Medical imaging Advanced visualization 3D/4D AI Surgical planning Diagnostics Cardiology Neurology Pulmonology CT vessel analysis CT perfusion Colon analysis Calcium scoring MR cardiac function analysis Lung resection planning Liver analysis Renal resection

Business Intelligence

Key InvestorsNantWorks
PartnershipsOlympus (March 2025), MMS Medicor Medical (2009)
AcquisitionsAcquired by NantWorks (2011)
TechnologyZiostation2, Revoras, PhyZiodynamics; Vendor-neutral, Multi-modality, AI-powered, Thin-client architecture, Customizable workflow, Enterprise solution, 3D printing enabled, Cloud-native (implied by 'anywhere' accessibility and web browser access for Versaweb)
FDA ClearancesMultiple FDA 510(k) clearances, including CT Dual kV (K200315), CT brain perfusion, MR cardiac function, Ziostation2 (K181892, K151212) cleared products (estimated)

What Physicians Need to Know

Medical Imaging & Advanced Visualization
Ziosoft specializes in cutting-edge 3D/4D AI-based visualization and quantitative analysis, offering a comprehensive suite of multi-modality (CT, MR, PET, Nuclear Medicine, X-Ray Angio, Ultrasound) advanced processing and viewing solutions. Their platforms, such as Ziostation REVORAS, feature photorealistic Rembrandt image rendering for enhanced clarity and understanding.
3D/4D AI & PhyZiodynamics
Leveraging AI and machine learning, Ziosoft's PhyZiodynamics 4D advanced processing platform provides an unprecedented 'real-time' journey through the body non-invasively. This technology supports precise surgical and radiation therapy planning and includes AI-powered automation for tasks like coronary calcium scoring, ensuring efficient and reproducible outcomes.
Surgical Planning & Simulation
Ziosoft offers advanced 3D simulation solutions for precise surgical and radiation therapy planning across various organ targets, including the brain, lungs, heart, liver, and kidneys. Their tools provide automatic segmentation, anatomical mapping, and 'stump perspective' emulation, aiding in complex procedures like lung resection, liver-sparing surgeries, and minimally invasive nephrectomies.
Cardiology Solutions
The platforms provide comprehensive CT/MR cardiac tools, including automated calcium scoring (Agatston score), CT coronary analysis, CT cardiac function assessment (ejection fraction, wall motion), CT myocardial perfusion, and MR cardiac function analysis (strain, perfusion, LGE, T1/T2 mapping, flow). They also support structural heart applications and EP planning.
Neurology & Pulmonology
For neurology, Ziosoft offers CT and MR brain perfusion analysis and MR tractography. In pulmonology, their solutions include CT lung applications for low-attenuation analysis and lung resection planning, featuring automatic segmentation of lungs, lobes, bronchi, pulmonary arteries, and veins, as well as virtual bronchoscopy.
CT Vessel & Organ Analysis
Specialized tools for CT vessel analysis include automatic extraction of coronary arteries and stenosis rate calculation. For abdominal organs, they provide CT liver analysis (segmentation, volume measurement, vessel visualization) and renal resection planning (3D representation of tumor-vessel positioning, resection simulation). Colon analysis features integrated computer-aided detection and virtual endoscopy views.
Physician Tip

Ziosoft's solutions are designed to significantly enhance diagnostic confidence and accuracy through superior image quality and advanced analytical tools. Physicians benefit from improved surgical planning and precision via real-time 3D/4D models, anatomical mapping, and AI-powered insights, leading to better patient outcomes. The platforms streamline workflow and increase efficiency with customizable interfaces, automated segmentation, and faster processing, reducing training burdens. Its vendor-neutral and scalable architecture ensures compatibility with existing systems and offers flexible deployment options (thin-client, web-based, subscription), minimizing capital investment. Additionally, features like photorealistic rendering (Rembrandt) aid in education and patient engagement, while collaborative tools facilitate communication among healthcare professionals. The proven image noise reduction also enables lower dose options for patients.

Ziosoft's platforms are DICOM compliant, ensuring broad compatibility with various imaging modalities and systems. They are built on a true vendor-neutral and multi-modality architecture, allowing for seamless integration with existing PACS and teleradiology systems. The highly scalable thin-client and web-based applications (VersaWeb) provide enterprise-wide access and real-time collaboration tools. Ziosoft also engages in strategic partnerships, such as with Olympus for AI-powered surgical planning tools and Medicsight for ColonCAD, to expand its integrated offerings.

Products by Ziosoft

1 product in the directory

Ziostation2
Ziosoft
Radiology & Imaging AI
Ziostation2 is Ziosoft's advanced visualization and AI-enabled medical imaging platform, providing comprehensive 2D, 3D, and 4D analysis across multiple modalities and specialties for efficient and repeatable diagnostic and surgical planning outcomes.

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Press & Coverage

AuntMinnie
Ziosoft updates Revoras advanced visualization platform
Ziosoft has released updates to its Revoras advanced visualization platform for CT and MRI images, adding new capabilities like a surgical imaging suite for various resection planning and supporting onsite CT coronary plaque analysis.
2026-03
PRWeb
Ziosoft to Showcase Latest REVORAS Thoracic Surgery Planning Software at the Annual American Association of Thoracic Surgeons Conference
Ziosoft will feature its REVORAS-enabled thoracic surgical planning capabilities at the AATS conference, offering critical analytical tools such as automatic pulmonary and vein segmentation and lung cancer treatment planning.
2026-05
PRWeb
Ziosoft Showcases Newest REVORAS AI Integrated Software Platform at Annual European Congress of Radiology Conference
Ziosoft is showcasing its newest REVORAS-based software at the European Congress of Radiology (ECR) conference, which offers comprehensive clinical application AV/AI integrated capabilities for CT and MRI images.
2026-03
AuntMinnie
Ziosoft forms partnership with Olympus
Ziosoft has partnered with Olympus to integrate its Revoras image analysis platform as an AI-powered clinical decision tool for preoperative surgical planning, initially focusing on thoracic, liver, and urologic surgery applications.
2025-03
PR Newswire
Olympus Announces Launch of AI-Powered Surgical Planning Tool Through Strategic Partnership with Ziosoft
Olympus has launched its first AI-powered clinical decision tool in collaboration with Ziosoft, with initial applications targeting liver, lung, and kidney procedures to optimize preoperative planning.
2025-03
PRWeb
Ziosoft Receives European Union MDR Certifications for Lung and Liver Surgical Planning Visualization Software
Ziosoft announced it has completed the European Union MDR process and cleared CE Mark for its innovative Revorasu2122 liver and lung Surgical Planning software.
2025-02
The Worldfolio
Healthcare with medical imaging and digital technologies
Shusuke Chino, President of Ziosoft, discussed the company's evolution, its innovative Ziostation REVORAS products, and the integration of AI to streamline workflows and provide detailed patient information.
2024-02
PRWeb
Ziosoft Introduces Zioflex Subscription Model at the Annual Radiology Society of North America
Ziosoft introduced Zioflex, a new subscription model for its AI-based software, designed to eliminate capital investment risk and offer flexible deployment models for healthcare facilities.
2021-11

Frequently Asked Questions

Ziosoft's flagship advanced visualization platform is Revoras, which, along with Ziostation2, offers cutting-edge 3D/4D AI-based visualization and quantitative analysis. These platforms provide comprehensive tools for cardiology (e.g., calcium scoring, MR cardiac function, CT vessel analysis), neurology (e.g., CT/MR brain perfusion, MR tractography), and pulmonology (e.g., lung resection planning, virtual bronchoscopy, CT pulmonary analysis). Ziosoft's solutions are vendor-neutral and support multi-modality imaging from CT and MR systems.
Ziosoft's Revoras platform leverages AI to convert CT and MR scans into real-time 3D models, significantly enhancing preoperative surgical planning and precision. This includes specialized applications for lung resection planning, liver analysis, and renal resection planning, enabling surgeons to visualize complex anatomies and simulate procedures. The platform supports detailed anatomical insights and collaboration between radiologists and surgeons for procedures like thoracic, liver, and urologic surgeries.
Ziosoft maintains a Quality Management System in full compliance with regulatory requirements, holding US FDA 510(k) and European CE Mark certifications. The company has also obtained ISO 9001 and ISO 13485 certifications, demonstrating its commitment to quality and information security. Recently, Ziosoft received European Union MDR certifications for its innovative Revoras liver and lung surgical planning software.
Ziosoft offers its advanced visualization solutions through a subscription model called Zioflex, designed to eliminate the need for capital investment and provide flexible terms. This model includes free software upgrades and technical support during the active subscription period. Ziosoft provides a dedicated customer support team for technical and clinical issues, with live support available Monday through Friday during Pacific Standard Time business hours.
Ziosoft has formed a strategic partnership with Olympus, integrating its Revoras platform as an AI-powered clinical decision tool for preoperative surgical planning in thoracic, liver, and urologic surgeries. Additionally, Ziosoft partners with distributors like MMS Medicor Medical Supplies GmbH to expand its market reach in regions such as Germany, Austria, and Switzerland. These collaborations aim to enhance surgical precision, streamline workflows, and provide broader access to Ziosoft's advanced imaging solutions.
Founded in 1998, Ziosoft is a recognized leader in functional CT/MRI 3D visualization and analysis software, with offices in Japan and the USA. The company has thousands of systems installed in over 30 countries worldwide and a history of continuous innovation in medical imaging. While one source indicates it is unfunded, its long operational history, global presence, and strategic partnerships suggest a stable and established business model.

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