United States-based Healthcare AI investors

Investors headquartered in United States actively deploying capital into healthcare AI. Filter by stage and check size to match the right firms to your round.

The United States is the foundational epicenter of global venture capital, deploying hundreds of billions annually. The ecosystem is defined by immense liquidity, unmatched risk tolerance, and a heavy concentration of paradigm-shifting mega-rounds in generative AI and core healthcare infrastructure.
826 investors match

Within United States: top investor types

VC (416) Solo Angel (124) PE (117) Corporate VC (110) Angel Network (17) Accelerator (15) Syndicate (14) Startup Studio (13)
Looking Glass Capital
VC AI T3
Denver, United States
$250k-$1M
Looking Glass Capital is a Denver-based early-stage firm working at the intersection of digital health and applied AI, and it represents the…
AI/ML in Healthcare Digital Health
LorientCapital
PE T3
Birmingham, United States
$5M-$25M
Lorient Capital is a Birmingham, Michigan private investment firm focused on scaling physician-led healthcare service organizations. The firm’s positioning leans operational, with…
Care Delivery / Tech-Enabled Services
Loup Ventures
VC AI T3
Minneapolis, United States
$250k-$1M
Loup Ventures is a Minneapolis-based venture firm founded by former Piper Jaffray analyst Gene Munster and his colleagues, focused on frontier technologies…
AI/ML in Healthcare Digital Health
LRVHealth
VC T3
Boston, United States
LRVHealth is a Boston-based healthcare-dedicated venture firm with one of the more distinctive structures in the category: its limited partners are predominantly…
AI/ML in Healthcare Care Delivery / Tech-Enabled Services
Luma Group
VC T3
San Francisco, United States
$5M-$25M
Luma Group is a San Francisco-based venture firm investing in healthcare companies, with a focus on biotech and pharma and therapeutics. The…
Biotech Pharma / Therapeutics
Lux Capital
VC AI T1
Menlo Park, United States
$5M-$25M
Lux Capital is one of the most distinctive deep-tech venture firms in the United States, and the firm’s posture toward healthcare reflects…
AI/ML in Healthcare Biotech
M12
Corporate VC T3
San Francisco, United States
M12 is Microsoft’s venture arm, investing across enterprise software, AI infrastructure, security, and selectively in health technology where the company integrates with…
AI/ML in Healthcare Biotech
Maccabee Ventures
VC T3
New York, United States
$250k-$1M
Maccabee Ventures is a Chicago-based early-stage generalist venture firm investing in technology companies with a particular community connection through the Jewish entrepreneurial…
AI/ML in Healthcare Care Delivery / Tech-Enabled Services
Madison Dearborn Partners
PE T3
Chicago, United States
$25M+
Madison Dearborn Partners is a Chicago private equity firm with a long-running buyout practice that includes healthcare among its target sectors, alongside…
Care Delivery / Tech-Enabled Services
Madrona Venture Group
VC T3
Seattle, United States
Madrona Venture Group is a Seattle-based generalist firm with a multi-decade track record of investing across enterprise software, AI infrastructure, and applied…
AI/ML in Healthcare Biotech
Magarac Venture Partners
VC T3
Pittsburgh, United States
$250k-$1M
Magarac Venture Partners is a Pittsburgh-based early-stage firm investing in technology companies in the broader Mid-Atlantic and Rust Belt region, with a…
Digital Health Medical Devices / MedTech
Manikanda Arunachalam
Solo Angel AI T3
San Francisco, United States
<$250k
Manikanda Arunachalam is a San Francisco-based investor associated with The Lotus Capital, writing $250K-plus checks at seed and Series A into medical…
AI/ML in Healthcare Digital Health
Marc Lore
Solo Angel AI T3
New York, United States
<$250k
Marc Lore is the serial commerce founder behind Diapers.com (sold to Amazon) and Jet.com (sold to Walmart for $3.3B), now building Wonder,…
Digital Health Wellness / Consumer Health
Marius Nacht
Solo Angel AI T3
Tel Aviv, Israel
<$250k
Marius Nacht is a billionaire angel investor, the co-founder of Check Point Software Technologies, who has aggressively pivoted into healthcare and now…
AI/ML in Healthcare Biotech
Mark Cuban
Solo Angel T3
Dallas, United States
<$250k
Mark Cuban occupies an unusual position in the healthcare investing landscape. As the founder of Cost Plus Drugs, the cash-pay generic pharmacy…
Health IT / Healthcare Software Pharma / Therapeutics
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