ExcelsiusGPS

by Globus Medical  · Based in United States →The World's First Revolutionary Robotic Navigation Platform
Neurosurgery Orthopedics

Paid

Overview

ExcelsiusGPS™ is a state-of-the-art robotic navigation platform developed by Globus Medical. It is designed to enhance safety, accuracy, and efficiency in spine and cranial procedures. The system combines a rigid robotic arm with full navigation capabilities, offering real-time trajectory guidance and visualization of integrated instruments and implants.

The platform supports a comprehensive approach to surgical procedures, from pre-operative planning to execution. It is compatible with various imaging modalities, including preoperative CT, intraoperative CT, and intraoperative fluoroscopy, with additional MR compatibility for cranial applications.

ExcelsiusGPS™ aims to reduce the surgeon’s cognitive load and improve patient care by providing continuous feedback and safety redundancies throughout the procedure. It is particularly beneficial for minimally invasive spine surgeries, potentially leading to smaller incisions, less tissue damage, shorter hospital stays, and quicker recovery times.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Rigid robotic arm for accurate trajectory alignment and stable positioning.
  • Full navigation capabilities for real-time guidance and visualization.
  • Compatibility with various imaging modalities (preoperative CT, intraoperative CT, intraoperative fluoroscopy, MR for cranial).
  • Real-time trajectory guidance and visualization of integrated instruments and implants.
  • Adaptable end effector for different spine and cranial applications.
  • Force deflection sensing for feedback on skiving and trajectory deviation.
  • Intuitive pre-planning software for streamlined surgical workflows.
  • Integrated instruments designed for robotic navigation.
  • Portable and maneuverable base station and camera stand.
  • Cohesive, integrated navigation camera that tracks all active and passive navigated arrays.

Use Cases

  • Spinal fusion procedures, including pedicle screw placement.
  • Transforaminal Lumbar Interbody Fusion (TLIF).
  • Lumbar Lateral Interbody Fusion (LLIF).
  • Sacroiliac (SI) fusion.
  • Cranial stereotactic procedures, such as biopsies and Deep Brain Stimulation (DBS).
  • Deformity correction and revision spine surgery.

What Physicians Need to Know

Brain MRI/CT Analysis
ExcelsiusGPS works with preoperative CT, intraoperative CT, intraoperative fluoroscopy, and MRI for cranial applications. It enables CT-MRI fusion and CT-to-fluoroscopy registration for streamlined workflows in procedures like frameless robotic stereotactic brain biopsies. The system allows surgeons to visualize, plan, and navigate patient anatomy in real-time using these imaging modalities.
Seizure Detection
ExcelsiusGPS is used in stereoelectroencephalography (SEEG) procedures, a critical tool for identifying epileptogenic zones in patients with drug-resistant epilepsy. The robotic system assists in accurate electrode placement for SEEG, which is crucial for seizure localization.
Neurodegenerative Disease Screening
ExcelsiusGPS Cranial Solutions can be used for complex Deep Brain Stimulation (DBS) procedures, which are relevant in managing certain neurodegenerative diseases.
Triage Prioritization Speed
The system is designed to improve OR efficiency and reduce surgery time through integrated planning, navigation, and robotic trajectory alignment. For instance, screw insertion time can be significantly reduced. This efficiency can contribute to faster patient throughput.
Physician Tip

ExcelsiusGPS offers real-time trajectory guidance and visualization, enhancing safety and accuracy in cranial and spinal procedures. Leverage its imaging versatility, including CT-MRI fusion, for comprehensive pre-operative planning and intra-operative navigation. The system's ability to maintain navigational integrity even with patient movement, through features like force deflection sensing and surveillance markers, provides added confidence during complex cases. For cranial procedures, the Cranial Solutions eliminate the need for a stereotactic arc, streamlining the workflow and potentially reducing surgery time.

ExcelsiusGPS is compatible with various imaging modalities, including preoperative CT, intraoperative CT, intraoperative fluoroscopy, and MRI for cranial applications. It is an open platform that can integrate a variety of instruments for stereotactic procedures, such as navigated biopsy needles and verification probes. The system's software allows for segmental merging of preoperative CT scans with intraoperative fluoroscopy images, even if vertebral bodies have shifted. The Excelsius Ecosystem, including the Excelsius3Du2122 imaging platform, provides an all-in-one imaging capability designed to improve implant placement accuracy, lower radiation exposure, and shorten operation times.

Details

Category Neurology AI, Surgical AI
Pricing Paid Typically ranges from $1 million to $1.5 million.
DeploymentOn-premise
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated

ExcelsiusGPS™ received FDA 510(k) clearance in 2017 for use in minimally invasive and open orthopedic and neurosurgical procedures, including screw placement applications in spine and orthopedic surgery.

Integrations
EHR Not specified
Specialties Neurosurgery, Orthopedics

What the Web Says

ExcelsiusGPS by Globus Medical is a robotic navigation system primarily used in spine surgery, and more recently for cranial procedures, designed to enhance precision and accuracy in screw and lead placement. Physicians highlight its ability to integrate navigation with a rigid robotic arm, leading to improved patient outcomes, reduced complications, and faster recovery times. The system aims to streamline surgical workflows and minimize radiation exposure for both patients and surgeons.

Overall: Positive

Strengths

  • Increased precision and accuracy in screw and lead placement, reducing revision rates.
  • Reduced radiation exposure for both patients and surgical staff.
  • Minimally invasive procedures, leading to smaller incisions, less blood loss, reduced post-operative pain, and quicker patient recovery.
  • Improved surgical efficiency and decreased procedural time, especially for complex cases or multiple screw placements.
  • Enhanced confidence for surgeons due to real-time feedback and GPS-like guidance.
  • Versatility for various spinal procedures, including complex deformities and revision surgeries, and expanding to cranial applications.

Limitations

  • High upfront capital investment, with a purchase price around $900,000 to $1.5 million, and significant total cost of ownership.
  • Steep learning curve for surgeons and operating room teams.
  • Limited published long-term outcome data and comparative studies for the ExcelsiusGPS platform specifically.
  • Potential for navigation errors or robot aborts in complex anatomical cases like severe scoliosis.
  • Some reviews on general software platforms like Capterra mention short or less detailed reviews, and potentially overwhelming filters, though these are not specific to ExcelsiusGPS.
  • Initial FDA clearance experienced a minor setback, indicating potential for regulatory hurdles.

Based on reviews from: Special Edition: Surgical Robots ExcelsiusGPSu00ae (Mid-Course Notes From Users), Globus ExcelsiusGPS Review & ROI Calculator - Robotomated, The Future of Spine Surgery: How the Globus ExcelsiusGPS System is Transforming Precision and Patient Outcomes at Overlook Medical Center - Clinician Resources, ExcelsiusGPS Robotic Navigation Spine Surgery, ExcelsiusGPSu2122 Patient Testimonial: Keturah F. - YouTube, Accuracy of Pedicle Screw Placement Using the ExcelsiusGPS Robotic Navigation Platform: An Analysis of 728 Screws - PMC, Life-Changing Robotic Spinal Surgery with the Excelsius GPS - YouTube, Clinical outcomes and complications of robotic-assisted spine surgery: using the ExcelsiusGPS system: a single-surgeon case series - PMC, ExcelsiusGPSu00ae Patient Testimonial: Dave B. - YouTube, Spine surgery using the Globus Excelsius GPS computer-assisted robotic device, Research and Clinical Evidence | Globus Medical, Keturah's ExcelsiusGPSu2122 Success Story - Globus Medical, Globus Medical marks 1st cranial surgery with ExcelsiusGPS - Becker's Spine Review, Globus Medical's spine robot: 5 things to know, Accuracy of Pedicle Screw Placement Using the ExcelsiusGPS Robotic Navigation Platform: An Analysis of 728 Screws - PubMed, Journal of Neurosurgery reviews robotic spinal surgery outcomes during the past decade - Reddit, Excelsius3D thoracic and cervical screw placement. : r/Neuromonitoring - Reddit, FDA deals setback to Globus Medical's ExcelsiusGPS robot-assisted surgery platform

Last updated: 2026-09-04

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Press & Coverage

BioSpace
Globus Medical Announces CE Mark for Excelsius3Du2122 Imaging System
Globus Medical announced that its Excelsius3Du2122 intelligent 3-in-1 imaging system has received CE mark for commercial sale in the European Union and the United Kingdom. This system expands the Excelsiusu2122 Ecosystem and integrates with ExcelsiusGPSu2122 for enhanced intraoperative imaging and robotic navigation.
2026-09
FDA
Globus Medical, Inc. Recalls ExcelsiusGPS Flat Panel Fluoroscopy Registration Fixture Due to a Calibration Error
Globus Medical, Inc. initiated a Class I recall for the ExcelsiusGPS Flat Panel Fluoroscopy Registration Fixture due to a calibration error that could lead to incorrect patient image alignment and potential misplacement of implants or instruments during spine surgery.
2024-01
PubMed (Global Spine Journal)
Proficiency Development and Learning Curve in Robot-Assisted Spine Surgery Using the ExcelsiusGPSu00ae System: Experience From a Single Institution
This study investigated the learning curve of robot-assisted spine surgery using the ExcelsiusGPSu00ae system, concluding that proficiency develops rapidly, with significant improvements in operative and screw placement times after a limited number of cases.
2024-04
PubMed (Journal of Robotic Surgery)
Clinical outcomes and complications of robotic-assisted spine surgery: using the ExcelsiusGPS system: a single-surgeon case series
A single-surgeon case series evaluating the ExcelsiusGPS system found high pedicle screw accuracy, low complication and revision rates, and significant postoperative symptom improvement, supporting its clinical non-inferiority to conventional methods.
2025-11
Atlantic Health
Overlook Medical Center adds ExcelsiusGPSu2122 robotic navigation system to enhance spine surgeries
Overlook Medical Center has adopted the ExcelsiusGPSu2122 robotic navigation platform to improve accuracy and safety in spine surgeries, offering enhanced visualization and potentially leading to less blood loss, shorter hospital stays, and more predictable outcomes for patients.
2024-11
Carolina Pines Regional Medical Center
Carolina Pines Regional Medical Center Becomes First in the Pee Dee to Acquire ExcelsiusGPSu00ae - A Revolutionary Robotic Navigation Platform
Carolina Pines Regional Medical Center announced the acquisition of the ExcelsiusGPSu00ae robotic navigation platform, becoming the first in the Pee Dee region to offer this technology for advanced precision and safety in spine surgery.
2025-11
Abrazo Health
Abrazo Scottsdale Campus Introduces Revolutionary Robotic Navigation Platform for Spine Surgery
Abrazo Scottsdale Campus has integrated the ExcelsiusGPSu00ae Robotic Navigation Platform to enhance patient safety and surgical accuracy in spine procedures, offering highly accurate screw placement and trajectory alignment while minimizing radiation exposure.
2025-11
Globus Medical
Third Annual Robotic Navigation Institute Meeting: Shaping the Future of Surgical Innovation
Globus Medical announced the successful conclusion of its Third Annual Robotic Navigation Institute Meeting, an event focused on advancing surgical innovation, with ExcelsiusGPSu2122 being a key topic of discussion.
2024-03

Videos

Product demos, reviews, and walkthroughs for ExcelsiusGPS.

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Frequently Asked Questions

ExcelsiusGPS utilizes AI for advanced image processing and segmentation, enabling highly precise 3D anatomical modeling for surgical planning. This AI-driven approach enhances trajectory accuracy and reduces the potential for human error during screw placement in spinal and cranial procedures, ultimately aiming to improve patient safety and neurological outcomes by minimizing invasiveness and optimizing implant positioning.
ExcelsiusGPS is FDA-cleared, ensuring it meets stringent safety and efficacy requirements for medical devices. Regarding patient data, it adheres to HIPAA regulations through secure data handling protocols, and its AI algorithms undergo rigorous validation processes to ensure accuracy, reliability, and unbiased performance in neurological applications.
Alternatives to ExcelsiusGPS include other robotic navigation systems like Mazor X Stealth Edition and various conventional neuronavigation platforms. While many offer navigation, ExcelsiusGPS differentiates itself with its integrated robotic arm for precise trajectory guidance. Comparisons often focus on the level of robotic assistance, AI-driven planning features, and the breadth of clinical evidence supporting accuracy and patient outcomes for specific neurological and spinal indications.
The cost of an ExcelsiusGPS system can vary significantly based on configuration and included features. Pricing models often involve an upfront capital expenditure, with additional costs for maintenance, service contracts, and disposable instruments. Stryker, the manufacturer, typically offers various financing and leasing options, which can be discussed directly with their sales representatives to accommodate different budgetary needs of neurological practices and hospitals.
While highly advanced, ExcelsiusGPS, like any technology, has limitations. Its AI is trained on existing data, which might present challenges in extremely rare or highly anomalous neurological anatomies not well represented in its training sets. Intraoperative challenges such as significant patient movement or unexpected anatomical shifts may require manual adjustments and careful surgeon oversight, as the system's real-time adaptability to unforeseen events is still dependent on surgeon input and decision-making.
Stryker provides comprehensive training programs for neurological surgeons and their surgical teams, covering everything from system setup and basic operation to advanced surgical planning and execution using the AI-driven features. This typically includes on-site training, didactic sessions, and ongoing technical support to ensure proficiency and optimal utilization of the ExcelsiusGPS system in various neurological and spinal procedures.
ExcelsiusGPS aims to reduce radiation exposure by optimizing imaging protocols and minimizing the need for repeated fluoroscopic shots. Its AI-powered navigation allows for more precise instrument placement with fewer images, as the system provides real-time tracking and guidance based on pre-operative scans. This can lead to a significant reduction in cumulative radiation dose for both patients and the surgical team during neurological and spinal surgeries.

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Suggest an Edit → | Last Verified: 2026-09-03 | First Added: 2026-09-03
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