Hyro AI Agents for Healthcare
Starting at $90,000
Overview
Hyro offers an Adaptive Communications Platform featuring AI agents designed to automate patient interactions across various channels, including call centers, websites, mobile apps, and SMS. The platform aims to streamline administrative functions such as patient scheduling, prescription management, and FAQ resolution, integrating seamlessly with existing EHRs and CRMs like Epic and Salesforce. By leveraging natural language understanding (NLU) and advanced knowledge graphs, Hyro’s AI agents can handle a high volume of routine patient inquiries, reducing staff workload, improving operational efficiency, and enhancing the overall patient experience. The solution is built with a strong focus on compliance, ensuring patient privacy and data security.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- AI Agents (Voice and Chat)
- Call Center Automation
- Smart Routing
- Scheduling Management (booking, rescheduling, cancellation)
- Rx Management (prescription refills, status)
- FAQ Resolution
- Physician and Location Search (Care Finder)
- Conversational Intelligence / Patient Journey Analytics
- Proactive Pxu2122 (Outbound AI Agents for reminders, follow-ups, billing notifications)
- EHR Integration (Epic, Salesforce, CRMs)
Use Cases
- Appointment Management (scheduling, rescheduling, cancellation, verification)
- Patient Access and Navigation
- Automating Call Centers
- Reducing Staff Burden/Burnout
- Improving Patient Experience/Engagement
- Billing Support/Payment Queries
- IT Help Desk/Password Resets
- Care Gap Closure/Referral Follow-ups
What Physicians Need to Know
Patient Portal Integration
Hyro integrates with major EHR/EMR systems like Epic, Oracle Cerner, eClinicalWorks, Athenahealth, and Meditech. It supports patient identification and MyChart troubleshooting via web-based AI assistants, and continuously scrapes EMRs for up-to-date information, eliminating manual data maintenance.
Appointment Scheduling AI
Hyro automates end-to-end appointment scheduling, rescheduling, verification, and cancellation 24/7 across phone, web, SMS, and mobile apps. It allows patients to find doctors, filter by attributes, and browse available time slots. The system features dynamic rescheduling, smart routing to the right provider/time/location, and waitlists to backfill canceled appointments, integrating seamlessly with Epic scheduling modifiers.
Symptom Checker Accuracy
Hyro partners with Infermedica, integrating its physician-led Medical Guidance Platform for early symptom assessment, triage, and care routing. This collaboration enables deeper symptom understanding, improved triage support, and clinically aligned patient guidance, aiming to reduce ER overuse by directing patients to the most appropriate care path.
Multi-Language Patient Support
Hyro's AI agents are designed to expand access for diverse patient populations with multilingual capabilities, ensuring broader community reach and improved patient experience.
Health Literacy Adaptation
Hyro employs Natural Language Understanding (NLU) to create user-friendly, adaptive conversational AI experiences, moving beyond rigid chatbots. Through a partnership with WebMD Ignite, it delivers clinically validated education content within its chat agent, applying decision logic to guide patients from questions to actionable next steps. The 'Spotu2122' GPT-powered search provides human-centric answers from trusted website content.
Chronic Disease Management
Hyro's Proactive Pxu2122 offers proactive outreach for overdue screenings and chronic condition management. It supports post-visit follow-ups to check on symptoms, confirm labs and medications, and book subsequent appointments, thereby improving care plan adherence and reducing readmissions.
Medication Adherence Features
Hyro provides Rx Management features, allowing patients to automatically refill prescriptions, get immediate pharmaceutical information, and track refill statuses (processing, submitted, in delivery, ready for pick-up). Patients receive text message updates, and the system includes proactive reminders for renewals and adherence nudges.
Patient Education Content
Hyro partners with WebMD Ignite to deliver clinically validated education content directly within its chat agents. This content is integrated with decision logic to recommend appropriate next steps, guiding patients through their care journey. Additionally, 'Spotu2122 GPT-Powered Search' generates instant, explainable answers from trusted website content.
Accessibility Compliance
Hyro is built on a 'Responsible AI' framework, emphasizing HIPAA compliance, secure patient verification, and data protection. It adheres to a 'Triple C Standard' for Clarity (explainable logic), Control (defined data sources to prevent 'hallucinations'), and Compliance (adapting to regulations and redacting PII/PHI).
Physician Tip
Leverage Hyro's AI to automate repetitive administrative tasks like scheduling and FAQ resolution, freeing up staff for more complex patient care. Utilize the actionable insights from patient journey analytics to identify trends, knowledge gaps, and optimize operational efficiency. Employ the physician search feature to accurately match patients with the right specialists, enhancing patient satisfaction and streamlining referrals. The system can also assist with pre-visit triage by gathering patient information and symptoms, allowing for better-prepared consultations.
Hyro offers extensive integration capabilities, functioning as a 'plug-and-play' solution with non-intrusive APIs for quick deployment. It integrates with leading EHRs (Epic, Oracle Cerner, eClinicalWorks, Athenahealth, Meditech), CRMs (Salesforce, Cheers CRM), and telephony systems (Cisco, Five9, RingCentral, Genesys, Avaya, Amazon Connect, Twilio). Key healthcare solution integrations include Kyruus for provider search, Gozio for mobile wayfinding, Infermedica for symptom assessment, Artera for patient communications, and WebMD Ignite for clinical education content. Hyro is a certified Epic app, available on the Epic Showroom, and continuously scrapes data from integrated systems to ensure information is always current.
Details
| Category | Patient Engagement & Education |
| Pricing | Starting at $90,000 — Subscription-based, per skill and per channel via tiered pricing. |
| Deployment | Multi-tenant SaaS, Cloud-based |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status | Unknown AI-estimated |
| Integrations | |
| EHR | Not specified |
| Specialties | Family Medicine, Internal Medicine, Pediatrics |
Ratings & Reviews
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Press & Coverage
Ynet News
Hyro bets AI agents can solve healthcare's growing access crisis - Ynet News
Hyro's 'responsible AI agents' are helping over 50 US healthcare systems manage patient demand, staffing shortages, and overloaded call centers by automating millions of voice and chat interactions annually. The company's systems automate 60% to 85% of repetitive patient interactions, reducing wait times and pressure on support teams.
2026-06
Great Entrepreneurs
Hyro's AI Agents Now Support More Than 50 U.S. Health Systems
Hyro has expanded its AI platform to over 50 U.S. health systems to automate routine patient interactions amidst staffing shortages and rising demand in call centers. The company's voice and chat agents handle tasks like appointment scheduling, prescription refills, and billing inquiries.
2026-07
PR Newswire
With Launch of Care Intelligence, Hyro Becomes the First to Turn Millions of AI Agent Conversations Into Patient Access Signals - PR Newswire
Hyro launched Care Intelligence, an analytics and agentic intelligence layer that transforms AI agent interaction data into strategic access insights for health systems. This solution helps health systems measure, benchmark, and optimize access to care using patient conversations handled by their AI agents.
2026-06
Fierce Healthcare
Hyro rolls out analytics platform to glean insights from AI agent interactions
Hyro's new Care Intelligence platform provides comprehensive analytics to help healthcare organizations optimize care access by analyzing AI agent interactions. The platform offers an overview dashboard for KPIs, sentiment analysis, and patient access insights, and can detect supply shortages and automation opportunities from patient conversations.
2026-06
PR Newswire
Hyro Partners with Five9 to Deliver Healthcare-Specific AI Agents to Contact Centers, Cutting Integration Time to One Hour
Hyro announced a partnership with Five9 to integrate its healthcare-native AI agents with the Five9 Intelligent Cloud Contact Center, significantly reducing integration times. This collaboration allows health systems to automate complex patient interactions at scale and can shorten integration deployments to as little as one hour.
2026-05
Cornell Tech
Cornell Tech Studio Startup Hyro Raises $45 Million to Scale Voice AI in Healthcare
Hyro, a health tech startup, raised $45 million in a growth investment round to scale its voice AI agents in healthcare. The funding will be used to develop AI agents that help patients navigate specialty care and remind them to schedule screenings.
2025-12
PR Newswire
Hyro Reveals Healthcare AI Agent Benchmarks Proving Deep EHR Integrations are Key to Unlocking Over $1M in ROI - PR Newswire
Hyro's 2026 Healthcare AI Agent Benchmark Report highlights that deep EHR integrations are crucial for health systems to achieve over $1 million in ROI from AI agents. The report, based on a survey of nearly 400 healthcare leaders, found that 82% of systems with advanced EHR integrations reported annual ROI exceeding $500,000.
2026-05
Sutter Health
Sutter Health Teams Up with Hyro to Revolutionize Patient Communications through AI
Sutter Health is collaborating with Hyro to integrate AI agents into its patient communication channels, including calls and messages for appointment management, scheduling, and billing. This partnership aims to enhance patient access and outcomes, boost inquiry resolution, and streamline employee workflows.
2025-09
Videos
Product demos, reviews, and walkthroughs for Hyro AI Agents for Healthcare.
How Responsible AI Agents Are Transforming Healthcare Call Centers | Interview with Hyro CEO
Frequently Asked Questions
Hyro AI Agents enhance patient engagement by automating routine interactions across voice, chat, and SMS, offering 24/7 self-service for tasks like appointment scheduling, prescription refills, and FAQ resolution. This reduces patient wait times and provides convenient access to information and services.
Hyro employs a 'Responsible AI' framework, adhering to a 'Triple C Standard' of Control, Clarity, and Compliance. This includes restricting data sources to prevent misinformation, providing explainability for AI decisions, and strictly complying with HIPAA regulations, including the redaction of PII/PHI.
Hyro AI is designed to intelligently route complex or sensitive inquiries to live agents with full context, ensuring a seamless handoff when human intervention is necessary. This allows staff to focus on more intricate cases while the AI handles routine tasks.
Hyro's pricing is generally subscription-based, tiered per skill and per channel, with reported starting costs around $90,000. While specific pricing details require a demo, some alternatives like AnveVoice offer flat pricing or free tiers, and others like JustCall AI Receptionist also provide AI voice agents.
While Hyro aims for high automation, some physicians might find limitations in the transparency of specific front-desk workflows or detailed patient identity verification methods. Additionally, despite AI adoption, a significant percentage of patients still express concerns about data security and prefer human interaction for sensitive information.
Yes, Hyro AI is built with deep EHR integration capabilities, including with systems like Epic and Salesforce. This allows the AI agents to read and write patient data in real-time for tasks such as appointment scheduling and prescription management.
Hyro addresses the risk of 'hallucinations' by restricting its AI to internal and approved data sources, thereby ensuring that responses are based on trusted information. This 'Control' pillar of their Responsible AI framework aims to provide accurate and reliable patient communications.
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| Last Verified: 2026-04-22 | First Added: 2026-04-22