Leal Health (formerly Trialjectory)
Overview
Leal Health, formerly known as Trialjectory, is an AI-powered patient-centric decision-support platform dedicated to democratizing access to advanced cancer treatment. It empowers patients to own their cancer journey by providing personalized treatment options, including relevant clinical trials and FDA-approved therapies. The platform also assists oncologists in finding personalized treatment options for their patients and supports pharmaceutical and biotech companies in developing patient-centric clinical trials and gaining real-time analytics on patient barriers and motivations.
Recognized by TIME as one of “The 100 Best Inventions of 2020” and an honoree in the AI and data category for Fast Company’s “2021 World-Changing Ideas Awards,” Leal Health leverages artificial intelligence to inform and empower cancer patients. The company has facilitated over 5.5 million treatment matches and partners with leading advocacy and patient support organizations to ensure unbiased access to cancer treatment.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- AI-Powered Instant Matching for treatments and clinical trials
- Dedicated Patient Support Team (PHDs, MDs, Nurses, Social Workers)
- No Pharma Bias in treatment recommendations
- Personalized list of cutting-edge cancer treatments
- FDA-approved cancer treatment decision support
- Patient Match Optimizer (for biopharma clients)
- Drug Treatment Optimizer (for biopharma clients)
- Predictive Patient Journey Solution
- GenAI solution for healthcare providers and patients
- Real-time analytics on patient barriers and motivations
Use Cases
- Matching cancer patients with relevant clinical trials
- Assisting oncologists in finding personalized treatment options
- Empowering patients to own their cancer journey
- Providing information for patients engaging in treatment conversations with doctors
- Enabling pharmaceutical and biotech industries to develop patient-centric clinical trials
- Analyzing real-world patient data to evolve oncology research
What Physicians Need to Know
For oncologists, Leal Health serves as a valuable AI-powered decision support tool to quickly identify personalized clinical trial matches and FDA-approved treatment options for cancer patients, reducing reliance on traditional, often time-consuming, search methods like ClinicalTrials.gov. The platform's ability to interpret genetic test results and integrate patient-specific data, including biomarkers and cancer subtypes, allows for highly tailored recommendations. By leveraging Leal Health, physicians can empower patients with a comprehensive understanding of their treatment landscape, address potential barriers to care, and facilitate access to advanced therapies, especially for underrepresented populations.
Leal Health's platform integrates with ClinicalTrials.gov to ensure access to a broad range of recruiting cancer trials. It is designed to integrate with pharmaceutical and biotech companies' existing online oncology clinical trial websites. The platform leverages a combination of generative AI (GenAI), Natural Language Processing (NLP), and machine learning models to analyze complex patient medical conditions and treatment criteria. Following its acquisition by Nexus Precision Health, Leal Health's technology is part of an integrated platform aimed at matching patients with cancer, rare genetic diseases, and mental health conditions to appropriate therapies, clinical trials, or expanded access pathways.
Details
| Category | Drug Discovery & Research, Oncology AI |
| Pricing |
Free for patients and oncologists; contact for biopharma pricing.
|
| Deployment | Web application |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status |
1 AI-estimated Leal Health has FDA-approved cancer treatment decision support, making it the industry's first and only single point of access to both FDA-approved treatments and clinical trials for cancer patients. |
| Integrations | |
| EHR | Not specified |
| Specialties | Hematology, Oncology |
What the Web Says
Leal Health, formerly known as Trialjectory, is an AI-powered platform designed to connect cancer patients with advanced treatments and clinical trials, aiming to democratize access to care. It offers personalized treatment matches based on a patient's medical profile, biomarkers, and preferences, and has expanded to include FDA-approved cancer treatment decision support. The platform is utilized by patients, caregivers, healthcare providers, and pharmaceutical companies to streamline the process of finding and enrolling in suitable trials.
Overall: PositiveStrengths
- Democratizes access to advanced cancer treatments and clinical trials for patients.
- Provides personalized treatment matches based on individual patient profiles, including genetic mutations and biomarkers.
- Empowers patients to take a more active role in their treatment decisions.
- Reduces reliance on unstructured data and expedites patient treatment identification and clinical trial enrollment for oncologists.
- Offers a single point of access to both FDA-approved treatments and clinical trials.
- Utilizes AI and generative AI to predict future treatment regimens and identify potential patients for trials.
Limitations
- Some general concerns about AI in healthcare, such as understanding unique patient journeys and potential for errors or hallucinations, have been acknowledged by Leal Health's CEO, though the company claims to have overcome these.
- The complexity and numerous capabilities of the platform might feel overwhelming to some users, as noted in reviews for similar clinical trial management systems on G2.
- Limited direct user reviews from physicians or healthcare IT professionals were readily available in the search results, making it difficult to assess specific pain points from these groups.
- No specific negative reviews from Reddit, G2, or Capterra directly pertaining to Leal Health (Trialjectory) were found in the provided search results.
Based on reviews from: StartupHub.ai, Medium, The Cancer Letter, BioSpace, CancerNetwork, Applied Clinical Trials Online, PR Newswire, Leal Health Website, PitchBook, Reddit, Fierce Biotech
Last updated: 2026-07-23
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Press & Coverage
Videos
Product demos, reviews, and walkthroughs for Leal Health (formerly Trialjectory).
Dr. Leal on the Rationale for the ECOG-ACRIN EA5161 Trial in ES-SCLC
OncLive
Frequently Asked Questions
Investors who backed Leal Health (formerly Trialjectory)
Funded through the company that built this tool.
