Medisafe
Freemium
Overview
Medisafe is a digital health platform designed to facilitate patient engagement, primarily for pharmaceutical companies. It aims to support patients in managing their medications and navigating treatment plans. The platform is utilized across various therapeutic areas, including cardiovascular, immunology, mental health, metabolic/GLP-1, neurology, and oncology, particularly for complex and specialty therapies where sustained patient engagement is considered critical.
- What it does: Medisafe provides digital tools to help patients with medication management and treatment plan adherence. For pharmaceutical companies, it extends patient support programs digitally to engage patients and aims to improve adherence and time on therapy.
- Who it is for: The platform is primarily for pharmaceutical companies to support their patient populations. It also offers tools for providers to reinforce treatment plans between visits and for patients to manage their own medication schedules.
- How it fits a clinical or practice workflow: In a clinical or practice workflow, Medisafe can serve as a digital adjunct to reinforce treatment plans and medication use between patient visits. It offers a mechanism for providers to extend support beyond the point of care through digital tools.
- Notable capabilities: Medisafe focuses on behavior-driven digital engagement. It is designed to activate patients earlier in their treatment journey and maintain engagement over time.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- Personalized medication reminders
- Medication tracking and adherence reporting
- Drug interaction warnings
- 90+ health measurement trackers
- Caregiver/family support (Medfriend)
- Refill and appointment reminders
- Complex dosage scheduling
- Digital drug companion programs (Enterprise)
- Predictive AI for non-adherence risk
- Omnichannel patient engagement
Use Cases
- Medication adherence improvement
- Chronic disease management
- Caregiver support and coordination
- Pharma patient support programs
- Clinical trial support
- Post-transplant medication management
What Physicians Need to Know
Patient Portal Integration
Medisafe offers a web-based reporting portal for patients to view their daily calendar and generate reports, which can be shared with their doctor. For iPhone users, Medisafe integrates with Health Records on iPhone, allowing automatic import of medications. Medisafe's Care Widgets also enable integration with existing patient support systems, allowing care coordinators to enroll patients in digital drug companion programs and share instructional videos.
Appointment Scheduling AI
Medisafe provides appointment reminders as part of its comprehensive features. The enterprise-level Care Connector platform also includes appointment management capabilities.
Multi-Language Patient Support
Medisafe offers multilingual interfaces and localization features, extending AI-driven personalization across languages. The Medisafe app itself can be switched to different language modes. Its AI voice agent, VIA, is also multilingual.
Health Literacy Adaptation
Medisafe aims to improve health literacy by providing medication educational content, including medication cards and videos. The app's user-friendly design and simple language contribute to its accessibility. Studies have shown high patient satisfaction and ease of use, even among medically underserved populations.
Chronic Disease Management
Medisafe significantly improves medication adherence for patients with chronic conditions like hypertension, diabetes, and heart disease. It offers tools to track over 90 measurements, including blood pressure, glucose, and cholesterol, with integration for Apple Health. The 'Pathways' web-based tool is specifically designed for managing FDA-approved treatments for chronic diseases, allowing HCPs to track patient visits, infusions, and treatment adherence.
Medication Adherence Features
Medisafe is a leading medication adherence platform, providing personalized, customizable reminders that require user confirmation. It offers complex dosage scheduling, drug interaction warnings, and refill reminders. The 'Medfriend' feature allows a designated friend or family member to be notified if a dose is missed, providing an additional layer of support. Medisafe's proprietary Just-In-Time Intervention (JITIu2122) AI predicts nonadherence risk and delivers targeted, personalized interventions.
Patient Education Content
The app provides medication educational content in the form of medication cards and videos. It also offers therapy-specific education and side-effect management. This content is tailored to each therapy and condition.
Accessibility Compliance
Medisafe is HIPAA and GDPR compliant, and ISO 27001:2013 and ISO 13485:2016/2022 certified, ensuring high levels of data security and quality management for medical devices. The app is designed to be user-friendly and intuitive, adapting to different screen sizes.
Physician Tip
Encourage patients, especially those with chronic conditions or complex medication regimens, to utilize Medisafe for improved adherence and self-management. Leverage the web-based reporting portal and Care Widgets to gain insights into patient adherence and engagement between visits, facilitating more informed conversations. Recommend the 'Medfriend' feature for patients who may benefit from additional social support. Utilize Medisafe's educational content to reinforce treatment plans and address patient questions regarding their medications and conditions. Consider integrating Medisafe's enterprise solutions for comprehensive patient engagement programs.
Medisafe offers robust integration capabilities through its Care Connector platform and SDK for enterprise clients (pharmaceutical companies, providers, and payers). It integrates with existing patient support systems, EHRs, CRM systems, and pharma's digital infrastructures. For individual users, it integrates with Apple Health and Health Records on iPhone. The VIA AI voice agent integrates across voice, SMS, app, and web, and can plug into brand hubs and CRM systems.
Details
| Category | Patient Engagement & Education |
| Pricing |
Freemium
|
| Deployment | SaaS, Cloud |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status |
Unknown AI-estimated Medisafe has achieved ISO 13485:2016 certification, which supports the design and development of Software as a Medical Device (SaMD) used for the diagnosis, prognosis, or prediction of disease progression. This certification affirms the company's commitment to quality management systems for medical devices. |
| Integrations | |
| EHR | Not specified |
| Specialties | Family Medicine, Hospital Medicine, Internal Medicine |
What the Web Says
Medisafe is a highly-rated medication reminder and management app praised by physicians, tech reviewers, and users for its effectiveness in improving medication adherence. It offers features like personalized reminders, drug interaction warnings, and caregiver support. While the free version has become more limited, many still find it invaluable for managing complex medication schedules.
Overall: PositiveStrengths
- Effective medication reminders and adherence tracking.
- User-friendly interface and easy to set up.
- Drug-to-drug interaction checker.
- Supports complex dose schedules and 'as needed' medications.
- Medfriend feature for family/caregiver support.
- Tracks various health measurements and offers refill and appointment reminders.
Limitations
- Free version is now limited to a small number of medications, requiring a paid subscription for full functionality.
- Reporting functionality can be difficult to navigate and limited for in-depth analysis.
- Some users report glitches or issues with updates.
- Lack of integration with medical records or pharmacies (beyond Android Wear).
- Notifications for Medfriends can be delayed.
- Not all medications have videos, and the app does not remind users to track measurements.
Based on reviews from: iMedicalApps, Tech-enhanced Life, G2, Gartner Peer Insights, Reddit (r/ADHD, r/ChronicPain, r/adhdwomen), intech.media, Apple App Store, Trustpilot, Minimalist Journeys, JMIR Human Factors (via Medisafe press release), Medium (Paul RYKEN), IntuitionLabs.ai, Google Play
Last updated: 2026-06-21
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Press & Coverage
Medisafe News & Events
Medisafe Launches VIA: AI Voice Tech That Supercharges Patient Engagement and Slashes Enrollment Friction
Medisafe launched VIA (Voice Intelligent Agent), an AI voice assistant designed to address the $5 billion patient support gap in pharma by transforming how specialty brands engage and retain patients. VIA integrates across voice, SMS, app, and web to provide proactive, empathetic voice calls that guide patients through onboarding, adherence, and access.
2025-04
Eisai Inc. Media Center
MedTech Breakthrough Recognizes Eisai, Biogen, and Medisafe for Alzheimer's Disease Treatment Innovation
Eisai Inc., Biogen, and Medisafe received the u201cBest Care Coordination Platformu201d award from MedTech Breakthrough for their PATHWAYS tool, which streamlines patient monitoring and enhances care coordination for Alzheimer's disease treatment. PATHWAYS is a web-based platform that assists healthcare providers in managing patients undergoing treatment with FDA-approved monoclonal antibodies for AD.
2025-05
Medisafe News & Events
Medisafe Announces Launch of GOMEKLIu2122 Digital Companion to Support Patients with NF1-PN Taking GOMEKLI
Medisafe collaborated with SpringWorks Therapeutics to launch the GOMEKLIu2122 (mirdametinib) Digital Companion, a platform designed to support patients with neurofibromatosis type 1 (NF1) and symptomatic, inoperable plexiform neurofibromas (NF1-PN). The companion provides personalized support, educational content, and medication tracking, integrating with SpringWorks' patient services program.
2025-05
Medisafe News & Events
Medisafe Demonstrates Significant Impact on Medication Adherence in Medically Underserved Populations
A study published in JMIR Human Factors revealed Medisafe's efficacy in improving medication adherence and health outcomes for chronically ill patients in medically underserved populations. The study showed significant improvements in medication adherence and self-efficacy, with high patient satisfaction and ease of use.
2025-02
Medisafe News & Events
Medisafe Launches PATHWAYS: A New Tool to Help Manage the Patient Journey
Medisafe launched PATHWAYS, a complimentary tool to streamline patient tracking and enhance care coordination for Alzheimer's Disease (AD) treatment. PATHWAYS helps healthcare providers, clinics, and infusion centers efficiently manage AD patients by tracking dosing and monitoring protocols for FDA-approved monoclonal antibodies.
2025-02
Medisafe News & Events
Novel Randomized Control Trial Reveals Impact of Medisafe on Medication Self-Efficacy and Medication Adherence to Improve Health Outcomes in Medically Underserved Populations
A randomized controlled trial published in the Journal of Behavioral Medicine found that Medisafe's app significantly improved medication adherence and self-efficacy in medically underserved populations with chronic illnesses within the first month of use. The findings suggest a large-scale benefit of implementing the free Medisafe app in Federally Qualified Health Center (FQHC) clinical settings.
2024-02
JMIR Human Factors
Satisfaction and Usability of a Commercially Available Medication Adherence App (Medisafe) Among Medically Underserved Patients With Chronic Illnesses: Survey Study
This survey study explored the satisfaction and usability of the Medisafe app among medically underserved patients with chronic illnesses, finding high satisfaction and ease of use. All participants (100%) would recommend the app to family and friends, and 93% found the reminders helpful for timely medication taking.
2023-12
PR Newswire
Medisafe Expands Business Solutions with New Software as a Medical Device (SaMD)
Medisafe announced its Software as a Medical Device (SaMD) technology, following its ISO 13485:2016 and ISO 27001:2013 certifications. This expansion signifies Medisafe's commitment to regulatory standards and its leadership in digital therapeutics, offering an interoperable, personalized, and patient-centric approach to digital patient connectivity.
2023-01
Videos
Product demos, reviews, and walkthroughs for Medisafe.
Medisafe Introduction
Medisafe
Frequently Asked Questions
Medisafe improves adherence through personalized reminders, educational content, and a supportive community. It tracks medication intake and offers insights into patient behavior, which can be shared with healthcare providers to tailor care plans.
Physicians can access patient adherence reports, missed dose alerts, and other medication-taking behaviors through Medisafe's provider platform, if the patient chooses to share this information. This data can be integrated into electronic health records (EHRs) for a comprehensive view of patient compliance.
While Medisafe is highly effective for many, patients with extremely complex regimens might still require additional support beyond the app. For those with significant cognitive impairments, direct caregiver involvement and supervision may be necessary, as app usage could be challenging.
Medisafe offers a more interactive and data-rich experience than traditional pill organizers, with features like gamification, educational content, and caregiver synchronization. Compared to other apps, it stands out with its robust community support and comprehensive tracking capabilities.
Medisafe offers a free version with core features, and a premium subscription (Medisafe Premium) that unlocks advanced functionalities like unlimited 'medfriends,' more reminder sounds, and detailed progress reports. Pricing for the premium version varies depending on the subscription plan.
Medisafe employs robust security measures, including encryption and adherence to HIPAA compliance standards, to protect patient data. They have a comprehensive privacy policy outlining how data is collected, used, and shared, emphasizing patient control over their information.
Medisafe offers integration capabilities with various digital health platforms and EHR systems, allowing for a more streamlined flow of patient adherence data directly into your practice's existing workflows. This can provide a more holistic view of patient health management.
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| Last Verified: 2026-06-19 | First Added: 2026-06-19
Investors who backed Medisafe
Funded through the company that built this tool.
