Oncospace

by Oncospace (now part of Sun Nuclear, a Mirion Medical company)  · Based in United States →AI-Powered Quality Enablement for Radiation Therapy Planning
Oncology

Regulatory Status Disclosed

Overview

Oncospace, now rebranded as Plan AI by Sun Nuclear, is a groundbreaking AI-powered data-mining system designed to enhance radiation therapy planning. Developed by Dr. Todd McNutt and his team at Johns Hopkins, it leverages artificial intelligence and machine learning to analyze the experiences of thousands of patients, helping radiation oncologists and dosimetrists craft optimal treatment plans tailored to individual needs while minimizing side effects.

The system provides an AI ‘assistant’ that predicts ideal doses and automatically creates AI-guided optimization objectives, integrating seamlessly with existing treatment planning systems like Varian Medical Systems® Eclipse™ and RaySearch RayStation®. Oncospace also offers a ‘Gateway’ solution for converting patient archives between different treatment planning systems.

Acquired by Sun Nuclear in April 2025, Plan AI aims to standardize and accelerate planning across institutions, ensuring high-quality, safe treatment and significantly streamlining workflows.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • AI and machine learning for radiation therapy planning
  • Predicts ideal dose and automatically creates AI-guided optimization objectives
  • Integrates with Varian Medical Systemsu00ae Eclipseu2122 and RaySearch RayStationu00ae
  • Treatment Planning Conversion (Gateway) for system migration
  • Predictive Plan Quality and Feasibility solution
  • Ready-to-use, FDA-cleared models trained on over 5,000 diverse cases
  • Cloud-based solution with enterprise-grade data security
  • Streamlined and intuitive interface for planning workflow
  • Supports expert planners by reducing variability and improving consistency
  • Provides patient-specific insights on achievable goals

Use Cases

  • Enhancing and standardizing radiation therapy planning
  • Optimizing patient outcomes in cancer treatment
  • Guiding dosimetry planning and plan optimization
  • Converting patient treatment planning archives between systems
  • Reducing planning time for radiation oncology teams
  • Improving consistency and quality of treatment plans

What Physicians Need to Know

Key Capabilities
AI-powered radiation therapy planning, predictive dose optimization, and data mining from thousands of patient experiences to generate optimal treatment plans. It balances tumor control with healthy tissue protection and includes a 'Gateway' solution for migrating patient archives between treatment planning systems (TPS).
Clinical Utility
Accelerates radiation planning, elevates plan quality and consistency, and acts as an AI 'assistant' for oncologists and dosimetrists. It helps craft optimal, patient-tailored treatment plans, minimizes side effects, and enables smaller practices to achieve advanced, evidence-based therapy standards.
Integration Options
Offers seamless script-based integration with existing Treatment Planning Systems (TPS) such as Varian Medical Systemsu00ae Eclipseu2122 and RaySearch RayStationu00ae. The Gateway solution specifically facilitates patient data migration from Philips Pinnacle to modern TPS platforms.
Compliance Status
FDA-approved for multiple cancer types, including prostate, gynecological, head and neck, liver, pancreatic, lung, esophageal, thorax, and abdomen. It also holds CE marking for regions requiring it. The system is built with HIPAA/GDPR-compliant architecture, ensuring EU data locality and encryption, backed by an ISO 27001-certified information security management system.
Pricing Model
Pricing information is not publicly disclosed and requires direct consultation with a Sun Nuclear representative.
User Experience
Designed to be an intuitive AI 'assistant' and guide, with a streamlined user interface developed in collaboration with Johns Hopkins Technology Innovation Center. It features ready-to-use, FDA-cleared models, eliminating the need for complex in-house model building and reducing the learning curve.
Support Quality
Backed by Sun Nuclear's global support, which includes a team with over 300 years of combined experience and more than 20 Medical Physicists. The focus is on easing technology adoption and enhancing workflow efficiency.
Implementation Complexity
Low complexity due to ready-to-use, FDA-cleared models that do not require hospitals to build their own. It is designed to complement, rather than replace, existing planning systems. The Gateway solution is a self-contained Windows application with minimal system requirements.
Evidence Base
Built upon a knowledge base derived from over 5,000 patient cases. It has undergone rigorous studies and external validation at institutions such as Johns Hopkins and Montefiore hospitals. Models are trained by anatomical region and validated using a five-fold validation model.
Physician Tip

For radiation oncologists and dosimetrists, Oncospace (Plan AI) can serve as a powerful AI assistant to quickly generate optimized treatment plans, predict achievable dose goals, and minimize side effects. Leverage its FDA-cleared, pre-built models to standardize and elevate plan quality across your practice, especially for common cancer types. The system's ability to provide patient-specific insights before planning begins can significantly streamline your workflow and improve communication within the treatment team. Ensure your team is trained to interpret the AI-guided objectives and integrate them effectively with clinical judgment.

Oncospace (Plan AI) is designed for seamless, script-based integration with major existing Treatment Planning Systems (TPS) like Varian Eclipse and RaySearch RayStation, preserving your current optimization workflows. Its 'Gateway' component is particularly valuable for facilities migrating from older systems like Philips Pinnacle, ensuring legacy patient data remains accessible and usable in modern DICOM formats. This focus on interoperability minimizes disruption and maximizes the utility of your existing infrastructure while enhancing it with AI capabilities.

Details

Category Oncology AI
Pricing Unknown
DeploymentCloud-based
Compliance
BAA Available Yes AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

Plan AI (formerly Oncospace) has received FDA 510(k) clearance for multiple cancer types, including prostate, head and neck, thoracic, abdomen, and female pelvis radiotherapy.

Integrations
EHR Not specified
Specialties Oncology

What the Web Says

Oncospace, now rebranded as Plan AI under Sun Nuclear, is an AI-powered software designed to enhance radiation therapy planning. It leverages data from thousands of patient experiences to create optimal, personalized treatment plans, aiming to minimize side effects and improve efficiency. Physicians have found the auto-plans delivered by Oncospace to be superior to their original plans and the interface intuitive and useful.

Overall: Positive

Strengths

  • Delivers higher-quality, patient-specific radiation treatment plans.
  • Streamlines workflow and peer review in radiation therapy planning.
  • Reduces toxicities and improves quality of life for patients.
  • Provides an advanced, validated model from day one, unlike other systems requiring hospitals to build models from scratch.
  • Offers a user-friendly and intuitive interface.
  • Helps ensure consistency and built-in safety checks in treatment planning.

Limitations

  • Challenges exist in data security when using medical data for training, though Oncospace aims to mitigate this by generating mathematical shape-relationship features that don't involve much identifiable information.
  • Initial skepticism from users regarding AI in radiation therapy, which can be overcome by demonstrating its effectiveness.

Based on reviews from: Medium, Johns Hopkins Medicine, Physics World, Business Wire

Last updated: 2026-07-18

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Press & Coverage

Sun Nuclear
Sun Nuclear Acquires Oncospace, AI-Focused Radiation Oncology Software Provider
Sun Nuclear, a Mirion Medical company, announced the acquisition of Oncospace, a provider of cloud-based, AI-powered solutions for the radiation oncology community. This strategic move aims to enhance radiation therapy quality assurance and improve treatment outcomes.
2025-04
DOTmed Healthcare Business News
Sun Nuclear acquires AI software firm Oncospace to bolster radiation oncology tools
Sun Nuclear's acquisition of Oncospace, an AI-driven software developer, is set to strengthen its digital offerings in radiation therapy quality assurance by integrating predictive analytics and cloud-based planning solutions. Oncospace's products, including Gateway for treatment planning system migration and a predictive plan quality solution, will be integrated into the Sun Nuclear brand.
2025-05
Physics World
Todd McNutt: how an AI software solution enables creation of the best possible radiation treatment plans - Physics World
Medical physicist Todd McNutt, co-founder of Oncospace, discusses how the AI-powered software, now rebranded as Plan AI and available from Sun Nuclear, uses data from thousands of previous radiotherapy treatments to predict optimal dose to healthy tissues for new patients. This streamlines and automates the creation of best achievable treatment plans.
2026-02
Sun Nuclear
Sun Nuclear to Highlight New Quality Management Solutions at 2025 AAPM Annual Meeting
Sun Nuclear will showcase significant additions to its radiation therapy quality management portfolio at the 2025 AAPM Annual Meeting, including Plan AIu2122 Software, an AI-powered treatment planning assistant from Oncospace. This application provides predictive, patient-specific insights for achievable goals before planning begins.
2025-07
National Institutes of Health (NIH)
Validating a framework for Pinnacle plan conversion and archival - PMC - NIH
This peer-reviewed article validates the use of Sun Nuclear Gateway, an Oncospace solution, for converting Philips Pinnacle treatment planning system data to DICOM format for archival and continued patient care, addressing the upcoming end of Pinnacle support.
2025-08
Physics World
AI-based tool improves the quality of radiation therapy plans for cancer treatment
A Physics World Weekly podcast features Todd McNutt, founder of Oncospace, discussing how the AI-based tool Plan AI, now a clinical product offered by Sun Nuclear, improves radiation therapy plan quality and personalizes treatment for cancer patients.
2026-01
BioSpace
Radiation Oncology Market Size to Surpass USD 32.82 Billion by 2034 - BioSpace
This market analysis highlights Sun Nuclear's acquisition of Oncospace in April 2025 as a key development in the radiation oncology market, emphasizing the commitment to leveraging AI-driven solutions to improve treatment outcomes.
2025-10
Towards Healthcare
AI in Oncology Market Transforms Cancer Diagnosis and Treatment - Towards Healthcare
The acquisition of Oncospace by Sun Nuclear in April 2025 is cited as a recent development in the AI in oncology market, demonstrating the industry's commitment to using AI-powered solutions for improved treatment outcomes.
2026-04

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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