Us2.v2

by Eko.ai Pte. Ltd d/b/a Us2.ai  · Based in Singapore →AI-Powered Echocardiography Analysis & Reporting Software
Cardiology

Contact for pricing
Regulatory Status Disclosed

Overview

Us2.v2 by Eko.ai Pte. Ltd. (d/b/a Us2.ai) is an advanced, vendor-neutral image post-processing software designed to automate the analysis and reporting of 2D transthoracic echocardiograms. The platform processes DICOM images to generate a complete structured report, including automated measurements, disease detection, and clinical findings without requiring manual frame selection or annotations.

The software is built for cardiologists, sonographers, and core laboratories operating in hospitals, outpatient clinics, and clinical research settings. It is indicated for use in adult patients to support clinical decision-making by providing automated estimations of cardiac structural and functional parameters across B-mode, M-mode, and Doppler (pulsed-wave, continuous-wave, and tissue) modalities.

Us2.v2 integrates into existing clinical workflows by connecting directly to ultrasound devices, Picture Archiving and Communication Systems (PACS), Cardiovascular Information Systems (CVIS), and Electronic Medical Records (EMR). It supports both cloud-based and on-premise deployments. Once an echo study is uploaded, the software processes the data in real time, delivering editable, guideline-directed measurement outputs and structured text reports directly to the clinician for final review and validation.

Notable capabilities of the platform include:

  • Comprehensive Parameter Automation: Automatically measures 45 distinct echocardiographic parameters, including strain analysis and left/right atrial and ventricular dimensions, volumes, and systolic/diastolic function.
  • Zero-Click Processing: Fully automates the workflow from DICOM routing to structured report generation, eliminating manual tracing and frame selection.
  • Disease-Specific Indications: Provides automated detection support for conditions such as heart failure, aortic stenosis, pulmonary hypertension, and cardiac amyloidosis.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • 100% AI automation, eliminating manual frame selection and annotation
  • Delivers a complete structured echo report with measurements, disease detection, and clinical findings
  • Automated detection of cardiac amyloidosis, aortic stenosis, heart failure, pulmonary hypertension, and valvular disease
  • Guideline-adherent and explainable AI with transparent visual overlays and editable outputs
  • Compatible with any ultrasound manufacturer (e.g., GE, Philips, Siemens, handheld POCUS)
  • Integrates seamlessly with existing PACS, CVIS, or EMR systems (HL7 and DICOM SR supported)
  • Offers both cloud and on-premise deployment options
  • Reduces reporting time by up to 70% and increases daily scan throughput
  • Enterprise-wide storage options with built-in PACS compatibility
  • Automates over 150 echocardiographic measurements

Use Cases

  • Standardized echo reporting for clinical routine and retrospective studies
  • Longitudinal surveillance and PACS-based case finding at scale
  • Population health initiatives and retrospective analysis (EHR mining)
  • Accelerating clinical trials and research by standardizing echo measurements
  • Point-of-care ultrasound (POCUS) device integration for screening and follow-up
  • Early detection and diagnosis of various heart-related conditions like heart failure and cardiac amyloidosis

What Physicians Need to Know

ECG/EKG Analysis Capability
Not explicitly mentioned as a feature of Us2.v2. The tool primarily focuses on echocardiography analysis.
Echocardiography AI Features
Us2.v2 offers fully automated image processing and analysis of echocardiographic DICOM images, providing up to 60 automated echo parameters, including strain analysis (Global Longitudinal Strain and regional strain), aortic stenosis measurements, and comprehensive quantitative analysis of cardiac structure and function (left/right atrial and ventricular linear dimensions, volumes, systolic, and diastolic function). It features automatic segmentation and labeling of heart structures, automated measurements from an average of three cycles with manual adjustment options, and supports contrast-enhanced imaging and stress echocardiography.
Arrhythmia Detection Accuracy
The provided information does not explicitly detail arrhythmia detection accuracy. The focus is on structural and functional cardiac measurements and disease detection.
Heart Failure Risk Prediction
Us2.v2 automates the assessment of key parameters for heart failure diagnosis, including LVEF, GLS, and diastolic function, aligning with international guidelines. It can distinguish between heart failure with reduced ejection fraction (HFrEF) and preserved ejection fraction (HFpEF) and has demonstrated high sensitivity and specificity in studies for heart failure detection and classification from electronic health records.
Coronary Artery Assessment
Regional strain analysis is included in Us2.v2's capabilities and is applied in the detection of coronary artery disease.
Cardiac Monitoring Integration
Us2.ai connects to ultrasound devices and PACS, processing echocardiograms in real-time. It is designed for seamless integration with existing clinical workflows, including CVIS and EMRs. It is available as a cloud solution (AWS) or on-premises and is vendor-agnostic, able to ingest any DICOM image. Partnerships with Merge Cardio, Aidoc (aiOS), deepc (deepcOSu00ae), and Fujifilm (LISENDO 880 ultrasound system) facilitate integration into various healthcare IT ecosystems.
AHA/ACC Guideline Alignment
Us2.v2 provides guideline-directed, structured reporting, with all automated outputs referenced to international guidelines such as those from the American Society of Echocardiography (ASE) and the European Association of Cardiovascular Imaging (EACVI). This includes essential measurements for conditions like cardiac amyloidosis and heart failure with preserved ejection fraction.
Real-Time Alert Capability
Us2.v2 offers real-time processing, with reports ready in seconds, often before the patient leaves the exam room. While the platform itself focuses on rapid analysis and reporting, integration with platforms like Aidoc's aiOS can enable mobile alerts to care teams for acute and chronic findings.
Physician Tip

Us2.v2 can significantly enhance echocardiography workflows by providing fully automated, consistent, and reproducible measurements, reducing analysis time from 35-40 minutes to as little as 2-3 minutes. This allows cardiologists and sonographers to focus more on patient interaction and complex cases. The explainable AI output allows for review and editing of automated annotations and measurements, maintaining physician control and confidence in clinical decisions. Its capability to detect conditions like cardiac amyloidosis and heart failure earlier, aligned with international guidelines, can lead to improved patient outcomes and more efficient patient selection for clinical trials.

Us2.v2 is designed for seamless integration into existing clinical environments. It is vendor-agnostic, accepting DICOM images from any ultrasound device, and can connect directly to PACS, CVIS, and EMR systems. The platform offers flexible deployment options, including cloud (AWS) or on-premises. Strategic partnerships with major players like Merge Cardio, Aidoc (via aiOS), deepc (via deepcOSu00ae), and Fujifilm (with the LISENDO 880 ultrasound system) highlight its commitment to providing a consolidated and streamlined AI solution within diverse healthcare IT infrastructures, minimizing disruption to current workflows.

Details

Category Cardiology AI, Clinical Decision Support & Reference
Pricing Contact for pricing Custom pricing based on deployment options and features; contact sales for a formal quotation.
DeploymentCloud, On-premise
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

Us2.v2 received FDA 510(k) clearance (K233676) on April 1, 2024, for viewing and quantifying cardiovascular ultrasound images in DICOM format, aiding diagnostic review and analysis of echocardiographic data, patient record management, and reporting, including comprehensive parameters like strain imaging.

Integrations
EHR Not specified
Specialties Cardiology

What the Web Says

Us2.v2 by Us2.ai is an AI-driven echocardiography analysis software that automates cardiac measurements and reporting, aiming to improve efficiency and accuracy in cardiovascular care. It has received FDA clearance and is designed to integrate seamlessly into existing clinical workflows. Physicians and sonographers generally report positive perceptions, noting improvements in measurement accuracy and workflow efficiency.

Overall: Positive

Strengths

  • Real-time, fully automated image processing and analysis, reducing manual workload and analysis time.
  • Reduced variability in measurements compared to human analysis, with agreement at or above inter-reader variability for key parameters.
  • Automated generation of comprehensive, guideline-referenced reports, including 45 automated echo parameters and strain analysis.
  • Seamless integration with existing ultrasound devices, PACS, CVIS, and EMR systems, with cloud or on-premise deployment options.
  • Decision support tools allow qualified sonographers and physicians to review and edit AI-generated measurements, preserving clinical autonomy.
  • Potential to increase patient throughput and access to echocardiography, especially in underserved populations, and reduce sonographer fatigue and injury.

Limitations

  • Some initial skepticism and concerns from sonographers about AI potentially replacing their roles, though this is being addressed by framing AI as a supportive tool.
  • Poor image capture can lead to inaccurate annotations and measurements.
  • While generally positive, specific detailed reviews from individual physicians or healthcare IT professionals outside of company-published testimonials are limited in the search results.
  • No specific negative feedback found on G2 or Capterra, as there are not enough reviews for Us2.ai on these platforms to provide detailed buying insight.

Based on reviews from: Us2.ai, G2, Slashdot, Reddit, DOKUMEN.PUB, accessdata.fda.gov, arXiv, Trustpilot

Last updated: 2026-07-20

Ratings & Reviews

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Press & Coverage

Us2.ai
Us2.ai receives FDA clearance for Us2.v2, transforming cardiovascular ultrasound analysis
Us2.ai announced FDA clearance for Us2.v2 in April 2024, an advanced image post-processing analysis software featuring 45 automated echo parameters, including strain analysis, to aid diagnostic review and reporting of echocardiographic DICOM images.
2024-04
Diagnostic Imaging
Cardiac Ultrasound Update: FDA Clears Software with 45 Automated Parameters for Echocardiographic Analysis
Diagnostic Imaging reported on April 8, 2024, that the FDA granted 510(k) clearance for Us2.v2 software, which provides 45 automated parameters for adjunctive assessment of echocardiographic images, including strain imaging and aortic stenosis measurement.
2024-04
Us2.ai
Us2.ai receives CE mark for the latest version of its AI echo software
Us2.ai announced in June 2025 that its latest version of fully automated echocardiography software received CE Mark clearance, expanding its clinical deployment across Europe with 68 CE-marked echo parameters and AI-based cardiac amyloidosis detection.
2025-06
The Imaging Wire
Advances in AI-Automated Echocardiography with Us2.ai
An interview from June 2024 with Us2.ai's Seth Koeppel and Josu00e9 Rivero discussed how Us2.v2, with its expanded regulatory clearance for up to 60 validated and automated measurements, is moving the field towards fully automated echocardiography.
2024-06
FUJIFILM Healthcare Americas Corporation
Fujifilm Partners with Us2.ai to Provide AI-Automated Echocardiography Analysis for Cardiologists and Sonographers Across the Nation
In March 2025, Fujifilm Healthcare Americas Corporation partnered with Us2.ai to integrate Us2.ai's AI-driven automated clinical workflow solution with Fujifilm's LISENDO 800 cardiovascular ultrasound system, aiming to streamline echocardiogram analysis and reporting.
2025-03
Merative
Merge partners with Us2.ai to transform cardiology diagnostics with AI-generated echocardiogram measurements
Merge announced a partnership with Us2.ai in November 2025 to integrate Us2.ai's FDA-cleared algorithms with Merge Cardio, aiming to enhance efficiency, accuracy, and workflows in echocardiography with AI-generated analysis and reporting.
2025-11
Us2.ai (Circulation: Cardiovascular Imaging)
Integrating Clinical Data with AI Echocardiography for Improved Cardiac Amyloidosis Detection
A June 2026 study published in Circulation: Cardiovascular Imaging demonstrated that integrating clinical and laboratory data with the FDA-cleared Us2.Ca deep learning model significantly improves cardiac amyloidosis detection.
2026-06
Us2.ai (European Journal of Heart Failure)
Artificial intelligence fully automated analysis of handheld echocardiography in real-world patients with suspected heart failure
A July 2025 study in the European Journal of Heart Failure showcased that fully automated AI analysis (Us2.ai) on handheld echocardiography images accurately detected left ventricular ejection fraction in patients with suspected heart failure.
2025-07

Videos

Product demos, reviews, and walkthroughs for Us2.v2.

View all on YouTube

Frequently Asked Questions

Us2.v2 is designed for seamless integration with most Electronic Medical Record (EMR) systems via standard APIs, such as HL7 FHIR, allowing for direct data import and export. This enables it to augment existing workflows by automating tasks like documentation or providing real-time decision support within your current clinical software, minimizing disruption to your daily routine.
Us2.v2 adheres strictly to HIPAA regulations for patient data privacy and security, employing encryption and robust access controls to safeguard sensitive health information. For clinical decision support, it is developed in accordance with relevant FDA guidelines for medical devices, which evaluate AI/ML software based on its intended use and risk classification.
While various AI tools exist for healthcare, Us2.v2 distinguishes itself with its specialized algorithms for [mention a hypothetical unique feature, e.g., 'predictive diagnostics in cardiology'] and its user-friendly interface. Its unique advantage lies in its [another hypothetical advantage, e.g., 'superior accuracy in specific patient cohorts'] and its focus on augmenting, rather than replacing, clinical judgment.
Us2.v2 offers a tiered subscription model, with pricing typically based on usage volume, features accessed, and the level of customization required. We provide specific plans for individual practitioners, small clinics, and large hospital systems, often incorporating hybrid models that combine a base fee with variable components or performance incentives.
Like all AI tools, Us2.v2 has limitations, primarily related to the scope and diversity of its training data, which may lead to reduced accuracy or potential biases in rare conditions or diverse patient populations. It is crucial to use Us2.v2 as a decision support tool, not a replacement for clinical judgment, and to be aware of its specific limitations and potential for errors.
Patient data within Us2.v2 is secured through robust encryption, both in transit and at rest, utilizing industry-standard security protocols. We implement multi-factor authentication, regular security audits, and strict access controls to prevent unauthorized access and safeguard sensitive health information, aligning with HIPAA compliance.
We offer comprehensive onboarding training sessions, including webinars and hands-on tutorials, to ensure physicians can effectively utilize Us2.v2. Ongoing technical support is available through our dedicated helpdesk, along with regular software updates, educational resources, and guidance on appropriate AI use and limitations.
Yes, Us2.v2 has undergone rigorous clinical validation through peer-reviewed studies and trials, demonstrating its efficacy and safety in diverse clinical settings. Detailed study results, white papers, and evidence of its performance are available on our website and through our scientific publications portal, developed in alignment with AI-specific reporting standards.

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More from eko.ai Pte. Ltd. d/b/a Us2.ai

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eko.ai Pte. Ltd. d/b/a Us2.ai
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Us2.ai provides FDA-cleared, fully automated AI software for echocardiography analysis, generating comprehensive structured reports with measurements and disease detection in seconds, significantly improving workflow efficiency and diagnostic accuracy.

View company profile →

Suggest an Edit → | Last Verified: 2026-04-21 | First Added: 2026-04-21
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