Vitrea CT Brain Perfusion
Overview
Vitrea CT Brain Perfusion is an advanced application within the comprehensive Vitrea Advanced Visualization suite, developed by Vital Images, now a Canon Medical Systems Group Company. This multimodality, vendor-agnostic platform provides full-powered clinical applications for 2D, 3D, and 4D advanced visualization and analysis. It is designed to standardize and consolidate radiology IT footprints, offering a scalable enterprise solution accessible anywhere and anytime through a thin-client deployment.
Specifically, Vitrea CT Brain Perfusion aids in assessing the whole brain and evaluating perfusion deficits by displaying 4D-DSA (digital subtraction angiography) views of blood flow in the vessels and 3D perfusion maps. It supports physicians in visualizing apparent blood perfusion in brain tissue affected by acute stroke. The tool offers a streamlined workflow with automatic curve-fitting, midline correction, motion correction, and region of interest templating. It automatically calculates quantitative brain perfusion results, including Regional Cerebral Blood Volume (rCBV), Mean Transit Time (MTT), Regional Cerebral Blood Flow (rCBF), Time-to-Peak (TTP), and Delay of tissue response curve.
The system also incorporates Bayesian processing, which excels at processing low signal-to-noise ratio (SNR) images, providing clarity on parametric images used to compute summary maps. A single-view Summary Map facilitates easy communication of perfusion results. Furthermore, Vitrea Advanced Visualization includes Global Illumination, a revolutionary 3D/4D rendering technique that provides a more photorealistic view of human anatomy, enhancing collaboration and patient communication.
Reviewed by Pouyan Golshani, MD — Interventional Radiologist
Key Features
- 2D, 3D, and 4D advanced visualization and analysis
- Multimodality and vendor-agnostic platform
- Scalable enterprise deployment options (Workstation, Extend, Enterprise)
- Accessible anywhere & anytime via thin-client solution
- Automatic calculation of quantitative brain perfusion results (rCBV, MTT, rCBF, TTP, Delay of tissue response curve)
- Single-view Summary Map for communicating perfusion results
- 4D cine of DSA view for visualizing contrast flow through vessels
- Streamlined workflow with automatic curve-fitting, midline correction, motion correction, and ROI templating
- Bayesian processing for improved clarity in low signal-to-noise ratio images
- Global Illumination for photorealistic 3D/4D rendering
Use Cases
- Assessing whole brain perfusion and evaluating perfusion deficits
- Visualizing apparent blood perfusion in brain tissue affected by acute stroke
- Identifying ischemic penumbra (dying brain tissue) for treatment decisions
- Supporting endovascular therapy decisions in acute ischemic stroke
- Pre-procedural and pre-operative planning
- Enhancing diagnostic confidence and data access in neuroimaging
What Physicians Need to Know
Vitrea CT Brain Perfusion is a critical tool for acute ischemic stroke assessment, aiding in the quantification of infarct and penumbra volumes to determine endovascular treatment eligibility. It provides comprehensive perfusion maps (CBV, CBF, MTT, TTP, Tmax, delay time) essential for identifying ischemic tissues and evaluating tissue viability. The Bayesian processing method enhances diagnostic confidence, particularly in acute stroke cases, by improving clarity in low signal-to-noise ratio images. The software's ability to visualize apparent blood perfusion helps differentiate between normal and diseased brain tissue.
Vitrea CT Brain Perfusion is a core application within the Vitrea Advanced Visualization platform. It seamlessly integrates with Canon's Automation Platform, which provides AI-based solutions for stroke management, including detection of Large Vessel Occlusion (LVO) and Intracranial Hemorrhage (ICH). Analyzed perfusion maps and related findings can be saved and displayed in PACS, streamlining the clinical workflow. As a multi-modality, vendor-agnostic solution, Vitrea Advanced Visualization can be integrated across various modalities and clinical service lines, including with Canon Aquilion ONE CT scanners for comprehensive stroke evaluations.
Details
| Category | Neurology AI, Radiology & Imaging AI |
| Pricing | Contact for pricing |
| Deployment | Workstation, Extend (up to 3 users), Enterprise (scalable thin client, single server for up to 6 concurrent users) |
| Compliance | |
| BAA Available | Unknown AI-estimated |
| HIPAA Compliant | Unknown AI-estimated |
| FDA Status |
1 AI-estimated Vitrea CT Brain Perfusion was cleared by the FDA under K181247 on November 20, 2018, as a radiological image processing system. It is a noninvasive post-processing application designed to evaluate areas of brain perfusion, calculating cerebral blood flow, cerebral blood volume, local bolus timing, and mean transit time from dynamic CT image data. |
| Integrations | |
| EHR | Not specified |
| Specialties | Emergency Medicine, Neurology, Radiology |
What the Web Says
Vitrea CT Brain Perfusion is a software application designed to assist physicians in visualizing apparent blood perfusion in brain tissue affected by acute stroke, aiding in the detection of acute cerebral infarcts and the assessment of penumbra and infarct volumes. It offers both 2D and 4D perfusion capabilities, with automated tools for streamlined workflow and quantitative results. Studies have compared Vitrea's accuracy in predicting infarct and penumbra volumes against other software like RAPID and Sphere, with varied results depending on the treatment cohort (intervention vs. conservative).
Overall: MixedStrengths
- Aids in visualizing apparent blood perfusion in acute stroke.
- Helps determine the presence of acute cerebral infarcts.
- Assists in assessing penumbra and infarct volumes.
- Offers streamlined workflow with automated features like curve-fitting, motion correction, and ROI templating.
- Provides quantitative results for various perfusion parameters (CBF, CBV, MTT, TTP, Tmax).
- Can be more accurate in penumbra assessment for conservatively treated patients compared to other software.
Limitations
- May overestimate infarct volume in patients undergoing intervention.
- All software, including Vitrea, tends to overestimate penumbra.
- Network infrastructure can be a bottleneck, impacting processing and transfer times, especially in teleradiology settings.
- CTP predictability of final infarct volume remains moderate across various software packages.
- Requires careful consideration of acquisition and processing times in stroke workups, particularly in smaller departments.
- Some physicians on Reddit question the necessity of CTP for every stroke code, especially with newer trials showing benefits of thrombectomy in large core infarcts.
Based on reviews from: Reddit, PubMed, FDA, Canon Medical Systems USA, ResearchGate, Canon Medical Systems Europe, Viz.ai, Canon Medical Systems Canada Limited, MDPI, YouTube
Last updated: 2026-07-20
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