XACT ACE Robotic

by XACT Robotics  · Based in Israel →Changing Interventional Procedures. For Good.™ Unparalleled Accuracy Unmatched Consistency Unlimited Efficiency
Interventional Radiology Oncology Radiology

Overview

The XACT ACE® Robotic System is a comprehensive robotic system designed for image-guided percutaneous procedures. It integrates image-guided planning and real-time monitoring with precise robotic insertion and S-Drive™ technology to deliver instruments to desired targets in the body. This hands-free robotic solution aims to improve targeting accuracy, efficiency, and consistency in procedures like biopsies and ablations. The system’s proprietary S-Drive™ technology allows for real-time, ongoing adjustments of the instrument trajectory to overcome tissue or target movement, enabling it to adapt from a linear to a non-linear path. This capability allows access to difficult-to-reach targets, including small tumors, lesions, or tissue samples, which may be challenging with manual insertion. The physician maintains clinical decision-making, creating a procedure plan that the robot then precisely executes. The system also features synchronized patient mounting, which quickly and securely attaches to the patient to compensate for movement, such as breathing. The XACT ACE® Robotic System has demonstrated an average tip-to-target accuracy of less than 1.7mm in clinical studies for biopsy procedures.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • S-Driveu2122 Technology for non-linear steering and motion compensation
  • Precise robotic instrument insertion and advancement
  • Image-guided planning software
  • Real-time monitoring and trajectory adjustment
  • Synchronized patient mounting
  • Hands-free operation
  • Instrument agnostic
  • Remote control capabilities (ACE Xtendu2122)
  • Average 1.7mm tip-to-target accuracy
  • Less than 8.5 minutes average skin-to-target time

Use Cases

  • Biopsies of difficult-to-reach tumors, lesions, or tissue samples
  • Ablation procedures
  • Drainage procedures
  • Targeted drug delivery
  • Accessing lung nodules with complex trajectories
  • Reaching lesions in mobile organs like the liver

What Physicians Need to Know

FDA Clearance Pathway
The XACT ACE Robotic System and its accessories have received FDA 510(k) clearance. This includes clearance for modifications to support robotic insertion and steering of ablation probes during clinical procedures.
Supported Modalities
The XACT ACE Robotic System is intended for use in Computed Tomography (CT) guided percutaneous procedures. It is designed to be compatible with multiple imaging modalities.
Reading Room Workflow Impact
The system is designed to improve physician workflows by enabling remote control from outside the procedure room, which can limit physician and staff exposure to radiation and reduce physical strain. Its small footprint and mobility allow for efficient setup within minutes, preventing disruption of clinical workflow and enabling easy transportation across multiple procedure rooms. The system aims to standardize procedures and potentially shorten procedure times, maximizing patient throughput.
AI Model Architecture (deep learning approach)
The XACT ACE Robotic System combines image-based planning and real-time monitoring with precise robotic insertion and proprietary S-Driveu2122 technology for non-linear steering. The S-Driveu2122 technology allows for ongoing adjustments to an instrument's trajectory to overcome movement and precisely reach targets without reinsertion. The system uses advanced algorithms for its non-linear steering capabilities and to compensate for target location changes due to patient breathing or movement.
Processing Speed (per study)
The system has been proven to achieve an average skin-to-target time of less than 8.5 minutes.
Sensitivity & Specificity Data
The XACT ACE Robotic System has demonstrated an unparalleled 1.7mm tip-to-target average accuracy upon first insertion. This accuracy has been validated in over 200 clinical and pre-clinical cases. Clinical studies have shown instrument tip-to-target accuracy of less than 3mm. An observational post-market study is compiling real-world data to evaluate the proportion of procedures where the instrument reached the pre-defined target and to assess system accuracy.
RSNA/ACR Validation
XACT Robotics has presented new data supporting advancements in accuracy, consistency, and efficiency of CT-guided percutaneous procedures with the XACT ACE Robotic System at the Radiological Society of North America (RSNA) annual conference. The company debuted its technology at RSNA 2019.
Physician Tip

The XACT ACE Robotic System is instrument-agnostic, allowing the use of instruments already stocked in your facility, which helps maintain physician preference and avoids additional investment. The system's remote-control capabilities (ACE Xtendu2122) can significantly reduce radiation exposure and physical strain for the interventional team. Its ability to compensate for patient and organ movement with S-Driveu2122 technology can lead to more consistent and accurate single-insertion targeting, potentially reducing procedure complexities and duration. The intuitive software design and short learning curve facilitate quick adoption and integration into clinical workflows, even for staff with varying experience levels.

The XACT ACE Robotic System integrates image-guided planning and real-time monitoring with its robotic insertion and steering capabilities. It is designed to fit seamlessly into existing clinical workflows due to its small footprint and instrument-agnostic nature. The system's remote-control unit, ACE Xtendu2122, allows for operation from the control room, enhancing workflow efficiency and safety by reducing radiation exposure. The system utilizes CT imaging for target trajectory planning and intraoperative tracking.

Details

Category Radiology & Imaging AI, Surgical AI
Pricing Unknown unknown
DeploymentOn-premise
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status Unknown AI-estimated

The XACT ACE® Robotic System received FDA clearance for CT-guided percutaneous procedures in July 2020. It has also received subsequent FDA clearances, including for its ACE Xtend™ Remote Control Unit in October 2022, allowing remote operation, and expanded support for ablation procedures in May 2022.

Integrations
EHR Not specified
Specialties Interventional Radiology, Oncology, Radiology

What the Web Says

The XACT ACE Robotic System is a hands-free robotic system designed to improve the accuracy, consistency, and efficiency of CT-guided percutaneous procedures such as biopsies, ablations, and drug delivery. It combines image-based planning and real-time monitoring with robotic instrument insertion and non-linear steering. The system aims to address challenges like radiation exposure, physical strain on physicians, and the difficulty of accessing small or moving targets.

Overall: Positive

Strengths

  • Unparalleled accuracy (less than 1.7mm average tip to target)
  • Consistent and predictable procedure times, often achieving target in a single insertion (average < 8.5 minutes skin to target time)
  • Reduces physical strain and minimizes radiation exposure for interventional radiologists and staff
  • Enables access to smaller and difficult-to-reach targets, potentially leading to earlier diagnosis and treatment
  • Compatible with various medical instruments and imaging modalities, allowing for a broad range of applications
  • Small footprint and mobile, allowing for efficient setup and transportation across different procedure rooms

Limitations

  • Some users of general Xact software (not specifically XACT ACE Robotic) found it comprehensive to set up for simple tasks and the interface a little too detailed
  • Integration issues with CRM systems were reported for a general Xact product, requiring manual data export
  • Pricing for a general Xact product was described as hard to understand
  • One Reddit user expressed concern about robot breakdown in a general discussion about robotic-assisted surgery
  • The lack of maneuverability for physicians when operating master-slave robots is a significant challenge

Based on reviews from: AI-Tech Park, PMC, MD+DI, CIO Bulletin, Ortho Spine News, Emory Healthcare News Release, Surgical Robotics Technology, XACT Robotics Case Studies, ClinicalTrials.gov, G2, Capterra, Reddit, YouTube

Last updated: 2026-09-04

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Press & Coverage

Breaking News
XACT ACE Robotic System Wins Expanded FDA Clearance
The XACT ACE Robotic System received expanded FDA clearance in June 2022, allowing it to support robotic insertion and steering of ablation probes during ablation clinical procedures. This expands its previous clearance for CT-guided percutaneous interventional procedures.
2022-06
MD+DI
XACT Is Changing the Tone of Robotics in Healthcare
XACT Robotics received FDA clearance for its XACT ACE Robotic System to support robotic insertion and steering of ablation probes during ablation clinical procedures. The system, about the size of an iPad, combines image-based planning and real-time monitoring with hands-free robotic insertion and non-linear steering.
2022-05
CIO Bulletin
XACT Robotics Launches Hands-Free Image-Based Robotic System - CIO Bulletin
Lahey Hospital & Medical Center acquired the XACT ACE Robotic System, making it the first U.S. hospital to offer robotic percutaneous procedures with this device. The system provides hands-free targeting with high accuracy for various procedures like biopsies, ablations, and drug delivery.
unknown
Applied Radiology
FDA Clears Additional Use of XACT ACE Robotic System During Ablation Procedures
XACT Robotics announced FDA clearance for a modification to its XACT ACE Robotic System to support robotic insertion and steering of ablation probes. This expands the system's indication for CT-guided percutaneous procedures, with over 200 clinical cases already performed.
2022-05
Interventional News
XACT Robotics receives FDA clearance for its ACE Xtend remote control unit
XACT Robotics received FDA clearance for its ACE Xtend remote control unit, enabling users to robotically insert and steer the XACT ACE Robotic System remotely from the control room. This feature aims to improve physician workflows, limit radiation exposure, and reduce physical strain during CT-guided percutaneous procedures.
2022-10
Emory News
Emory first in Southeast to use XACT ACE Robotic System to improve cancer detection
Emory Healthcare became the first in the Southeast to utilize the XACT ACE Robotic System for interventional radiology procedures, aiming to improve cancer detection by guiding physicians to smaller and harder-to-reach cancerous growths more quickly and accurately.
2022-11
XACT Robotics Press Release
XACT Roboticsu00ae Receives FDA Clearance for its ACE Xtendu2122 Remote Control Unit
XACT Robotics announced FDA clearance for its ACE Xtend Remote Control Unit, a first-of-its-kind feature for CT-guided percutaneous procedures. This allows remote operation of the XACT ACE Robotic System, improving physician workflows and reducing radiation exposure.
2022-10
PR Newswire
XACT Roboticsu00ae to Present New Data Demonstrating Unparalleled Accuracy and Advancements for Interventional Procedures Enabled by the XACT ACEu00ae Robotic System
XACT Robotics announced that leading interventional radiologists would present new data at RSNA 2021, showcasing advancements in accuracy, consistency, and efficiency of CT-guided percutaneous procedures using the XACT ACE Robotic System. The company also introduced ACE Xtend, enabling remote activation of the system.
2021-11

Videos

Product demos, reviews, and walkthroughs for XACT ACE Robotic.

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Frequently Asked Questions

The XACT ACE Robotic System is designed for seamless integration with most existing radiology imaging systems and Picture Archiving and Communication Systems (PACS) through standard DICOM protocols. This allows for efficient transfer of images and patient data, minimizing disruption to current workflows.
The XACT ACE Robotic System utilizes AI for advanced image analysis, real-time guidance during procedures, and automated trajectory planning. These features aim to improve precision, reduce procedure times, and potentially lower radiation exposure for both patients and staff.
The XACT ACE Robotic System has received FDA clearance and CE mark approval, ensuring its compliance with stringent medical device regulations in both the United States and European Union. It also adheres to HIPAA guidelines for patient data privacy and security.
While highly advanced, the XACT ACE Robotic System may have limitations in navigating extremely complex anatomical variations or in certain highly specialized interventional procedures requiring unique instrument articulation. Ongoing software updates and hardware advancements are continuously expanding its capabilities.
The costs for the XACT ACE Robotic System vary based on configuration and service agreements. Institutions can typically expect a capital expenditure for acquisition, along with annual maintenance and software licensing fees. Various financing and leasing options are available and can be discussed with XACT representatives.
The XACT ACE Robotic System differentiates itself through its unique combination of AI-powered image analysis, real-time robotic guidance, and a compact footprint. While other systems offer aspects of robotic assistance, XACT ACE focuses on a comprehensive solution for precision and efficiency in a broad range of interventional procedures.

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Suggest an Edit → | Last Verified: 2026-09-03 | First Added: 2026-09-03
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