Xeleris V Processing and Review Systems

by GE Healthcare  · Based in United States → — Virtual processing and review solution for nuclear medicine with advanced AI applications, offering mobile and scalable access.
Nuclear Medicine Oncology Radiology

Enterprise
Regulatory Status Disclosed

Overview

The Xeleris V Processing and Review Systems by GE Healthcare is a virtualized, flexible, and AI-powered solution designed for nuclear medicine and radiology practitioners. It transforms the nuclear medicine workflow by eliminating the need for a dedicated, fixed processing and review workstation, providing secure, mobile, and scalable access to data across an entire network.

Powered by GE’s Edison platform, Xeleris V integrates advanced Artificial Intelligence (AI) applications to streamline workflows and expedite diagnoses. Key AI-enabled applications include Q.Volumetrix AI, Q.Lung AI, Q.Thera AI, and EXINI Bone, which offer automated, deep learning-based segmentation and quantitation capabilities for SPECT/CT and PET/CT data.

Core capabilities encompass image processing, review, and reporting of nuclear medicine images, data display, quality control, image manipulation, quantification analysis, transfer, storage, and printing. The system aids physicians in diagnosis and treatment planning by providing enhanced image visualization, quantification, and monitoring of patient radiation doses.

Xeleris V is offered as an upgrade to existing Xeleris workstations or through GE Healthcare’s Smart Subscription service, which ensures systems are synchronized and always current with the latest software.

Important Note: This tool is a medical imaging processing and review system, not an AI tool for a physician directory. Its purpose is to assist nuclear medicine and radiology practitioners in interpreting medical images and planning treatments.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Virtual Processing and Review Solution
  • AI-enabled Clinical Applications (Q.Volumetrix AI, Q.Lung AI, Q.Thera AI, EXINI Bone)
  • Mobile and Flexible Access (Thin-client)
  • Scalable for multi-user and multi-site facilities
  • Automatic Deep Learning-based Segmentation
  • Quantitation and Dosimetry Calculations
  • Smart Subscription for automatic software updates
  • Supports SPECT/CT and PET/CT data
  • Image processing, review, and reporting
  • Enhanced image visualization and quality control

Use Cases

  • Nuclear Medicine image processing and review
  • Preoperative functional assessment of lung cancer
  • Pulmonary Embolism evaluation
  • Nuclear Oncology (quantitation and dosimetry)
  • Bone Metastases from Prostate Cancer (EXINI Bone)
  • Cardiac imaging analysis and function evaluation

What Physicians Need to Know

Key Capabilities
Xeleris V is a virtual processing and review solution for nuclear medicine, integrating advanced AI applications powered by GE's Edison platform. It offers automated, deep learning-based segmentation and quantitation for SPECT/CT and PET/CT data, including specific applications like Q.Volumetrix AI, Q.Lung AI, Q.Thera AI, EXINI Bone, and Q.Liver. Core functions encompass image processing, review, reporting, data display, quality control, image manipulation, quantification analysis, transfer, storage, and printing. It provides a mobile, scalable, and accessible thin-client solution, eliminating the need for dedicated, fixed workstations.
Clinical Utility
The system streamlines workflows and expedites diagnoses in nuclear medicine by aiding physicians with enhanced image visualization, quantification, and patient radiation dose monitoring. AI-enabled applications improve efficiency and precision in nuclear oncology through automated segmentation and dosimetry calculations. For instance, Q.Thera AI can reduce processing and dose calculation time by over 55%, and AI-enabled lung segmentation has shown an 89% success rate and a 57% reduction in clicks for lung cancer and pulmonary embolism assessments. EXINI Bone assists in evaluating bone metastases from prostate cancer, while Q.Liver enhances liver assessment and dose calculation for SPECT/CT.
Integration Options
Xeleris V is designed as a virtual solution accessible across an entire network and integrates with GE Healthcare's nuclear medicine scanners. It supports DICOM 3.0 for interoperability, allowing exchange of images, curves, and reports with other DICOM-compliant systems. The software can be installed on a remote server and offers integration with third-party applications via the Smart Subscription service. An IHE Integration Statement is available, detailing its conformance with the IHE Technical Framework.
Compliance Status
The system is cleared by the U.S. FDA as a Class II medical device (Regulation Number: 21 CFR 892.2050, Product Code: LLZ). Xeleris V is a modification of the predicate device, Xeleris 4.0, with similar indications for use, including additions for new applications like EXINI Bone and Q.Liver. It was developed, verified, and validated under GE Healthcare's Quality Management System (QMS), adhering to software development lifecycle standards. Q.Thera AI is also cleared for use within Xeleris V.
Pricing Model
Xeleris V is available as an upgrade for existing Xeleris workstations or through GE Healthcare's Smart Subscription service. The Smart Subscription ensures systems are 'always current' with the latest software. Pricing is quotation-based, varying by facility size, deployment, and chosen advanced AI applications, following an enterprise model with non-publicly transparent pricing. The subscription offers a base package with options to add individual application packages or an 'Unlimited Edition' for a single annual fee per MI system.
User Experience
The system is designed to enhance user mobility, flexibility, and access by removing the constraints of dedicated workstations. Its thin-client, scalable architecture simplifies and enhances workflows. AI-enabled applications automate time-consuming tasks like segmentation and quantitation, reducing manual clicks and improving overall efficiency. It provides secure access to data from various locations.
Support Quality
GE Healthcare provides service maintenance training for Xeleris V to Nuclear Medicine Field Engineers. The Smart Subscription service ensures that systems remain 'always current' with the latest software updates. Support contact information for GE Healthcare Service Representatives or a Call Center is available for assistance.
Implementation Complexity
Xeleris V can be installed on a remote server and is scalable for multi-user to multi-site facilities. It requires integration with GE Healthcare's nuclear medicine scanners. Integrating with non-GE systems necessitates careful analysis of application requirements and thorough workflow definition. Training courses are offered for installation and configuration.
Evidence Base
AI-enabled lung segmentation has demonstrated an 89% success rate and a 57% reduction in clicks. Q.Thera AI has shown an average reduction of 58% in user time for processing and dose calculation. Market research highlights the need for such solutions, with 73% of radiologists anticipating operational efficiency as a major challenge and 64% of clinicians reporting intensified burnout. FDA 510(k) clearance documents reference design verification, bench, and clinical testing confirming substantial equivalence to predicate devices.
Physician Tip

Leverage Xeleris V's virtual and mobile access for flexible workflow and remote study review. Utilize the AI-powered segmentation and quantification tools (e.g., Q.Volumetrix AI, Q.Lung AI, Q.Thera AI, EXINI Bone, Q.Liver) to reduce manual effort and enhance diagnostic precision and efficiency, particularly in nuclear oncology and lung/bone assessments. Consider the Smart Subscription model for continuous access to the latest software updates and AI applications. Be aware of the potential for significantly reduced processing and dose calculation times with AI applications, which can free up time for patient interaction.

Xeleris V is designed for seamless integration within the GE Healthcare ecosystem, especially with their nuclear medicine scanners. It supports DICOM 3.0 for broad interoperability with other DICOM-compliant systems for image and data exchange. While it offers a virtualized environment, integrating with non-GE systems requires careful planning and validation to ensure smooth workflows and data accuracy. The Smart Subscription service also facilitates integration with a growing selection of third-party applications.

Details

Category Oncology AI, Radiology & Imaging AI
Pricing Enterprise
  • Available via outright purchase or through a Smart Subscription service; quotation-based and varies depending on facility size, deployment, and selection of advanced AI applications
DeploymentCloud, On-premise, Hybrid
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

Cleared by the FDA as a Class II medical device (21 CFR 892.2050, Product Code LLZ). The original clearance, K201103, was granted on September 25, 2020, for digital processing, review, and reporting of medical images. A modification, K221680, was cleared on March 1, 2023, introducing Q. Thera AI and Generate Planar applications.

Integrations
EHR Not specified
Specialties Nuclear Medicine, Oncology, Radiology

What the Web Says

GE Healthcare's Xeleris V Processing and Review Systems is a virtual solution for nuclear medicine that aims to eliminate the need for dedicated, fixed workstations. It offers mobile and scalable access to data across a network and integrates advanced AI applications powered by GE's Edison platform to streamline workflows and expedite diagnoses. The system is designed for nuclear medicine and radiology practitioners in hospitals and multi-site healthcare systems, providing enhanced image visualization, quantification, and patient radiation dose monitoring.

Overall: Positive

Strengths

  • Eliminates the need for dedicated, fixed nuclear medicine workstations.
  • Provides secure, mobile, and flexible access to data across the network.
  • Includes cutting-edge AI applications for automated tasks like segmentation and quantitation, improving efficiency and precision.
  • Highly scalable for multi-user and multi-site healthcare facilities.
  • Kept 'always current' via the Smart Subscription service, ensuring continuous updates.
  • Aids physicians in diagnosis and treatment planning by providing enhanced image visualization, quantification, and monitoring of patient radiation doses.

Limitations

  • No specific cons were found in the provided search results.
  • Data encryption is not supported for data transfer on a Virtual Local Area Network (VLAN) using DICOM-TCP.
  • There are no products available to access the proprietary local database outside the Xeleris application.
  • Some users on Reddit mentioned difficulties syncing Xeleris with non-GE cameras.
  • The Aladdin editor, used for custom workflows, is no longer officially supported.
  • The system can be expensive, especially with floating licenses.

Based on reviews from: IntuitionLabs, GE HealthCare (United States), GE Healthcare Introduces Advance AI solutions in Nuclear Medicine, GE Healthcare Introduces Virtual Solution with AI Enabled Applications for Nuclear Medicine, Xeleris V with Advanced AI-powered Applications - YouTube, accessdata.fda.gov, GE HealthCare (Global English), GE Launches Virtual Server Solution with AI-enabled Applications for Nuclear Medicine, Veterans Affairs, Reddit, GE Xeleris, Q.Suite SpeedNuclear Imaging Workflow, Accessing Nuclear Medicine Images Remotely, ECU Health Chowan Hospital - NC DHHS, G2

Last updated: 2026-07-19

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Press & Coverage

GE Healthcare
GE Healthcare Introduces Advance AI solutions in Nuclear Medicine
GE Healthcare launched Xeleris V, a new virtual processing and review solution with AI-enabled applications, providing nuclear medicine clinicians secure access to data from anywhere, anytime, to simplify and enhance workflows.
2021-05
Imaging Technology News (ITN)
GE Launches Virtual Server Solution with AI-enabled Applications for Nuclear Medicine
GE Healthcare's Xeleris V eliminates the need for a standalone nuclear medicine workstation, offering clinicians secure access to data from various locations and utilizing AI-enabled applications to streamline workflows and expedite diagnoses.
2021-05
HealthImaging
GE Healthcare Introduces Virtual Solution with AI Enabled Applications for Nuclear Medicine
GE Healthcare unveiled Xeleris V, a virtual processing and review solution for nuclear medicine that integrates AI-enabled applications to enhance workflows and provide clinicians with advanced data for personalized care decisions.
2021-05
X-ray Interpreter (FDA Radiology AI Device Database)
Xeleris V Processing and Review Systems | FDA Radiology AI Device - X-ray Interpreter
Xeleris V is a nuclear medicine software platform that processes, reviews, and quantifies medical images from nuclear medicine, PET, and associated CT or MR scans, supporting various clinical applications with AI-based image analysis.
unknown
YouTube (GE HealthCare)
Xeleris V with Advanced AI-powered Applications - YouTube
This video highlights Xeleris V as a virtual image processing and review solution for nuclear medicine, featuring quantitative, AI-powered applications like Q.Volumetrix AI, Q.Lung AI, Q.Thera AI, and Q.Liver, designed to improve efficiency and accuracy.
2023-06
GE Healthcare
GE Healthcare Advances Precision Health & Theranostics With New Products & Solutions
GE Healthcare announced Xeleris V as a new virtualized, flexible AI-powered solution providing clinicians secure access to data from anywhere, aiming to enhance personalized care decisions and treatment recommendations.
2021-06
GE HealthCare
Xeleris V Molecular Imaging | GE HealthCare (Global English)
Xeleris V is GE HealthCare's virtual processing and review solution for nuclear medicine, eliminating standalone workstations and centralizing applications for mobile, scalable, and accessible access across a network, with advanced AI applications.
unknown
PubMed Central (PMC)
Enhancing Interoperability and Harmonisation of Nuclear Medicine Image Data and Associated Clinical Data - PMC
This review article discusses the current state of interoperability and harmonization of image and clinical data in nuclear medicine, including approaches to prepare datasets for artificial intelligence applications and commercial solutions.
2022-06

Videos

Product demos, reviews, and walkthroughs for Xeleris V Processing and Review Systems.

View all on YouTube

Frequently Asked Questions

Xeleris V integrates AI-enabled applications like Q.Volumetrix AI and Q.Thera AI to automate tasks such as organ segmentation and quantitation in SPECT/CT and PET/CT data. This helps streamline workflows, expedite diagnoses, and enhance precision in nuclear oncology and dosimetry calculations.
Xeleris V is designed and manufactured under 21 CFR 820 and ISO 13485 quality system regulations and has received FDA 510(k) clearance. As a virtual solution, its architecture provides a high level of security and data accessibility for patient information across a network.
While Xeleris V is primarily integrated with GE Healthcare scanners, other nuclear medicine processing software like MIM and Hermes are mentioned as alternatives in the market. These systems may offer varying degrees of AI capabilities and multi-vendor compatibility, which would require specific evaluation.
Xeleris V is available through an outright purchase or a Smart Subscription service. Pricing is quotation-based and depends on factors such as facility size, deployment method (cloud, on-premise, hybrid), and the specific advanced AI applications selected.
Xeleris V primarily requires integration with GE Healthcare's nuclear medicine scanners, and public information on extensive third-party integration is limited. While AI automates tasks like segmentation, physicians still review outputs, and the system's AI-based lung segmentation demonstrated an 89% success rate, indicating a need for oversight.
Through the Smart Subscription service, Xeleris V systems are kept synchronized to each other and to the latest software, ensuring they are 'always current' with automatic updates. This approach aims to integrate new AI applications and features as they become available to meet evolving clinical needs.
GE Healthcare offers online courses for Xeleris V covering installation, configuration, and updates, primarily recommended for field engineers. While specific physician training details are not extensively detailed, the Smart Subscription ensures systems are up-to-date, implying ongoing support for new features and functionalities.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18
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