Second Opinion® Panoramic

by Pearl  · Based in United States → — Smarter Radiology.
Dentistry

Subscription-based
Regulatory Status Disclosed

Overview

Pearl’s Second Opinion® Panoramic is an advanced, FDA-cleared artificial intelligence (AI) platform designed to assist dental professionals in analyzing panoramic radiographs. It leverages machine learning models trained on extensive datasets of expertly annotated dental X-rays to enhance the accuracy, speed, and consistency of radiographic analysis.

The platform provides real-time AI-powered visualizations and color-coded detections, highlighting suspected pathologies such as caries (incipient and progressed), periapical radiolucencies, calculus, bone loss, and impacted third molars. This visual aid helps dentists make more precise diagnostic decisions, reduce diagnostic uncertainty, and effectively communicate findings to patients, leading to increased treatment acceptance.

Second Opinion® Panoramic is part of Pearl’s broader suite of AI solutions for dentistry, which includes capabilities for 2D intraoral X-rays, 3D CBCT imaging (Second Opinion® 3D), and pediatric patients. It integrates seamlessly with existing imaging and practice management software, streamlining workflows and providing objective insights for improved clinical consistency and patient care.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Real-time AI pathology detection
  • Color-coded visual overlays on radiographs
  • Analysis of panoramic, bitewing, periapical, and CBCT images
  • Detection of caries, bone loss, periapical radiolucencies, calculus, and impacted third molars
  • Patient education and communication tools (e.g., patient health reports, comparison mode)
  • Integration with existing imaging and practice management systems
  • AI-powered treatment planning support
  • Automated segmentation of anatomical structures in 3D scans
  • Clinical consistency and standardization
  • Image enhancement

Use Cases

  • Enhanced diagnostic accuracy and consistency
  • Improved patient communication and treatment acceptance
  • Streamlined clinical workflows
  • Proactive identification of treatment opportunities
  • Clinical training and calibration
  • Support for insurance claims validation

What Physicians Need to Know

Dental X-Ray Analysis
Second Opinionu00ae Panoramic is a real-time AI platform that automatically detects numerous conditions in dental X-rays, including pathologies, existing restorations, and natural anatomy in panoramic, bitewing, and periapical radiographs. It acts as a 'second set of eyes' for dentists, enhancing diagnostic precision and accuracy by reducing human error and analyzing radiographs in 30 seconds or less.
Caries Detection Accuracy
The tool detects early and progressed decay, including incipient and interproximal caries, with 94% accuracy for hard-to-see disease. Dentists using Second Opinionu00ae AI have shown a 37% increase in diagnostic accuracy for pathologies in X-rays. It has achieved 97.01% accuracy in binary classification for healthy teeth and teeth with caries in pediatric dental radiograph datasets and identifies suspected caries on panoramic images.
Periodontal Assessment
Second Opinionu00ae Panoramic assists in periodontal assessment by detecting early bone loss, calculus, and periapical radiolucencies. Its capabilities can lead to more accurate periodontal diagnoses, and automated assessment of radiographic bone loss in panoramic imaging has shown promise.
Treatment Planning AI
The AI enhances accuracy and efficiency in diagnosis and treatment planning, supporting precise clinical decisions and helping dentists make confident decisions faster. AI-initiated second opinions have been shown to improve clinician accuracy in predicting pulp status for advanced caries treatment. However, it's important to note that the AI serves as an assistive tool, and the ultimate responsibility for treatment decisions remains with the practitioner.
Dental Imaging Integration (CBCT/Panoramic)
Second Opinionu00ae is specifically designed for panoramic X-rays, alongside bitewing and periapical images. Pearl also offers Second Opinion 3Du00ae for CBCT scans, which transforms complex scans into clear, actionable 3D insights within minutes, with automated segmentation of clinically relevant anatomy like dentition, maxilla, mandible, IAN space, sinus, nasal space, and airway.
Practice Management Integration
The tool integrates seamlessly with various practice management systems (PMS) and imaging software, including Software of Excellence (EXACT), Oryx Dental Software, Planmeca Romexis, and CS Imaging. This integration streamlines diagnostic processes, consolidates patient data and radiographic analyses, and boosts overall practice efficiency and consistency.
Patient Communication Tools
Second Opinionu00ae displays AI findings in real-time on patient-facing screens, utilizing clear, color-coded overlays and labels to help patients visualize and understand their oral health conditions and recommended treatments. This enhanced communication can boost case acceptance by 30% and includes features like tooth parts mapping and comparison mode to illustrate disease progression.
Orthodontic Planning
The tool contributes to orthodontic planning by accurately identifying impacted third molars on panoramic images. While not a dedicated orthodontic planning AI, its precise diagnostic capabilities for various dental conditions, including bone loss, provide foundational information crucial for comprehensive orthodontic treatment decisions, especially in complex cases involving extractions or jaw surgery.
Physician Tip

Utilize Second Opinionu00ae as a powerful 'second set of eyes' to augment your diagnostic capabilities, but always integrate its findings with your professional judgment and clinical expertise. Leverage the clear, color-coded visual outputs to enhance patient education and foster trust, which can significantly improve case acceptance and patient engagement in their treatment plans. Prioritize early detection of subtle pathologies, such as incipient caries and early bone loss, to enable more conservative and preventative interventions, ultimately leading to better long-term patient outcomes.

Second Opinionu00ae Panoramic offers robust integration capabilities with leading dental practice management systems (e.g., Software of Excellence/EXACT, Oryx Dental Software) and imaging platforms (e.g., Planmeca Romexis, CS Imaging). It can function as both a standalone tool and a seamlessly integrated solution, allowing clinicians to view AI annotations directly within their existing software workflows, thereby streamlining diagnostic processes and consolidating patient data for enhanced efficiency and accuracy.

Details

Category Dental AI
Pricing Subscription-based
  • Starting from $299.00 per month; typically $300-$500 per month for subscription plans; one-off setup fee of approximately $500 USD
DeploymentCloud-based; integrates with existing dental software.
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

Pearl's Second Opinion® has received multiple FDA 510(k) clearances, including for 2D and 3D dental radiologic image analysis, panoramic radiographs, and pediatric patients as young as 4 years old. It is cleared to identify suspected caries, periapical radiolucencies, impacted third molars, and anatomical structures in CBCT scans.

Integrations
EHR Not specified
Specialties Dentistry

What the Web Says

Pearl's Second Opinionu00ae Panoramic is an AI-powered software designed to assist dental professionals in detecting and localizing dental pathologies on panoramic radiographs. It has received FDA 510(k) clearance for identifying suspected caries, periapical radiolucencies, and impacted third molars. The software is praised for its high accuracy and ability to improve patient communication and case acceptance.

Overall: Positive

Strengths

  • High accuracy in detecting pathologies (94-95% pathology detection accuracy).
  • FDA cleared for 2D and 3D imaging.
  • Integrates with over 30 imaging and practice management platforms.
  • Enhances patient communication and case acceptance with visual AI annotations and color-coded overlays.
  • User-friendly interface.
  • Provides real-time analytics through Practice Intelligence.

Limitations

  • Higher cost compared to some competitors (starts at $299.00 per month with an additional setup fee).
  • Does not currently allow manual import of X-rays into the software.
  • Can produce false positives and may miss some findings, requiring double-checking by the clinician.

Based on reviews from: The Molar Report, FeaturedCustomers, Second Opinion by Pearl Review. Dental AI Assisted Diagnostics!, Dental Economics, Reddit, Physician Ai Tools, accessdata.fda.gov, Innolitics, New Dental Hygiene Technology in 2026: Top Updates

Last updated: 2026-07-18

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Press & Coverage

PR Newswire
Pearl's Second Opinionu00ae Panoramic Receives FDA Clearance for AI-Powered Dental Radiograph Analysis
Pearl announced that its Second Opinionu00ae Panoramic AI software, designed to detect and characterize a broad range of dental conditions from panoramic X-rays, has received FDA 510(k) clearance.
2023-11
Dentistry Today
Pearlu2019s Second Opinionu00ae Panoramic AI Software Receives FDA Clearance
Dentistry Today reported on Pearl's achievement of FDA 510(k) clearance for its Second Opinionu00ae Panoramic AI software, highlighting its capabilities in analyzing panoramic radiographs for various dental conditions.
2023-11
Fierce Biotech
Pearl's AI-Powered Dental Software Gets FDA Nod for Panoramic X-Ray Analysis
Fierce Biotech covered the FDA clearance of Pearl's Second Opinionu00ae Panoramic, emphasizing its role in enhancing diagnostic capabilities for dentists by leveraging AI for comprehensive panoramic X-ray analysis.
2023-11
DrBicuspid.com
Pearl's Second Opinionu00ae Panoramic Achieves FDA Clearance
DrBicuspid.com announced the FDA clearance for Pearl's Second Opinionu00ae Panoramic, detailing how the AI solution assists dentists in identifying and characterizing dental pathologies from panoramic radiographs.
2023-11
Dental Products Report
Pearl's Second Opinionu00ae Panoramic: A Breakthrough in Dental AI
Dental Products Report highlighted the significance of Pearl's Second Opinionu00ae Panoramic FDA clearance, describing it as a breakthrough in dental AI for its ability to analyze panoramic X-rays with high accuracy.
2023-12
FDA
FDA 510(k) Clearance for Pearl's Second Opinionu00ae Panoramic
This is the official FDA 510(k) clearance document for Pearl's Second Opinionu00ae Panoramic, detailing the product's classification, indications for use, and regulatory approval.
2023-11
Healthcare IT News
How AI is Revolutionizing Dental Diagnostics: A Look at Pearl's Second Opinionu00ae Panoramic
Healthcare IT News explored the impact of AI on dental diagnostics, featuring Pearl's Second Opinionu00ae Panoramic as a prime example of how technology is improving accuracy and efficiency in dental practices.
2024-01
GlobeNewswire
Pearl's AI-Powered Second Opinionu00ae Panoramic Expands Global Reach
GlobeNewswire reported on the global expansion of Pearl's Second Opinionu00ae Panoramic, indicating its growing adoption in international markets following its successful FDA clearance and proven efficacy.
2024-02

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18

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