Second Opinion® CS

by Pearl  · Based in United States → — FDA-cleared AI that detects dental disease with 94% accuracy. Catch early decay, diagnose consistently, and increase case acceptance by 30%.
Dentistry

Contact for pricing
Regulatory Status Disclosed

Overview

Pearl’s Second Opinion® CS is an AI-powered radiology solution specifically designed for dental clinicians. It provides real-time pathology detection, automated clinical annotation, and measurement capabilities, enhancing the diagnostic and case presentation experience. The software seamlessly integrates with existing imaging platforms, such as Carestream Dental’s CS Imaging, allowing for instant AI analysis and annotations directly within the workflow. Second Opinion® CS assists in the chairside detection of a wide range of dental conditions, including decay, infection, bone loss, periapical radiolucencies, and impacted third molars, across various radiograph types including bitewing, periapical, panoramic, and 3D CBCT scans. It aims to improve diagnostic accuracy, consistency, and patient communication through clear, compelling visual aids and exportable patient reports.

Reviewed by Pouyan Golshani, MD — Interventional Radiologist

Key Features

  • Real-time AI pathology detection (caries, bone loss, periapical lesions, impacted third molars)
  • Automated clinical annotation and measurement capabilities
  • Case presentation tools with clear visuals and AI highlights
  • Seamless integration with existing imaging software (e.g., CS Imaging)
  • Supports 2D (bitewing, periapical, panoramic) and 3D (CBCT) radiographs
  • High accuracy (94% for dental disease detection)
  • Automated segmentation for precise lesion shapes and anatomical structures
  • Patient health reports with annotated visuals
  • AI-powered bone level analysis
  • Enhances diagnostic consistency and efficiency

Use Cases

  • Chairside diagnostic aid for dentists
  • Patient education and communication
  • Treatment planning (implants, orthodontics, oral surgery, airway management)
  • Increase case acceptance
  • Insurance submissions
  • Periodontal evaluation

What Physicians Need to Know

Dental X-Ray Analysis
Second Opinionu00ae CS provides real-time AI analysis and annotations directly within CS Imaging software, detecting and measuring a wide range of dental conditions such as decay, infection, bone loss, periapical radiolucencies, calculus, and faulty restorations. It utilizes AI-generated polygonal contours for precise lesion shapes and detailed contextual information.
Caries Detection Accuracy
The software employs machine learning for caries detection and segmentation in periapical radiographs. Studies indicate a sensitivity for caries detection greater than 70%, with subgroup sensitivities of 0.95 for enamel and 0.86 for dentin. It offers detailed analysis of lesion overlap with dentin and enamel as a percentage. Pearl states its AI is 94% accurate in detecting dental disease.
Periodontal Assessment
Second Opinionu00ae CS assists in identifying bone loss and calculus. It provides automated, color-coded measurements from the crest of the bone to the cementoenamel junction (CEJ) to indicate severity (White: 0-2.5 mm; Yellow: 2.5-4 mm; Amber: >4 mm).
Treatment Planning AI
The tool offers deeper insights to inform diagnosis and treatment planning through precise lesion shapes and contextual information, helping clinicians make confident decisions faster by analyzing radiographs in 30 seconds or less.
Dental Imaging Integration (CBCT/Panoramic)
Second Opinionu00ae CS is seamlessly integrated with Carestream Dental's CS Imaging platform (version 8), allowing for effortless viewing of AI annotations in the same software used for image capture, viewing, and storage. Pearl also offers Second Opinion 3Du00ae, an FDA-cleared AI for 3D radiology that transforms CBCT scans into intuitive, color-coded 3D visualizations with automatic segmentation and highlighted findings.
Practice Management Integration
The software integrates with practice management systems (PMS) to streamline workflows, surfacing chairside radiograph findings directly in the PMS to support documentation and case presentation.
Patient Communication Tools
Second Opinionu00ae CS features compelling case presentation tools with clear visuals, including AI-detected pathologies and clinical annotations. It uses intuitive color-coding, clear decay metrics, and 'Tooth Parts' mapping to enhance patient understanding of diagnoses and treatment plans, thereby boosting patient trust and case acceptance.
Physician Tip

Utilize Second Opinionu00ae CS as a powerful 'second set of eyes' to enhance diagnostic accuracy and consistency, particularly for subtle pathologies. Leverage its patient communication tools, such as color-coded overlays and 'Tooth Parts' mapping, to improve patient understanding and foster trust, which can significantly increase case acceptance. Remember that while the AI provides valuable insights and support, the final diagnosis and treatment plan remain the responsibility of the clinician. Integrate the AI findings seamlessly into your existing workflow within CS Imaging to maximize efficiency and minimize software switching. Regularly review the AI's suggestions to refine your diagnostic skills and ensure comprehensive patient care.

Second Opinionu00ae CS is natively integrated with Carestream Dental's CS Imaging platform (version 8), providing a streamlined workflow where AI analysis and annotations are displayed directly within the imaging software. This eliminates the need to switch between multiple applications. The broader Pearl AI suite also offers integration with various practice management systems (PMS) to facilitate documentation and case presentation, and includes Second Opinion 3Du00ae for advanced CBCT analysis.

Details

Category Dental AI
Pricing Contact for pricing
DeploymentIntegrated with existing imaging software (e.g., CS Imaging); Cloud-based portal for CBCT scans
Compliance
BAA AvailableUnknown AI-estimated
HIPAA CompliantUnknown AI-estimated
FDA Status 1 AI-estimated

Pearl's Second Opinion® CS holds FDA 510(k) clearance (K243234) as a computer-aided detection (CADe) software to aid dentists in the detection and segmentation of caries in periapical radiographs for patients 12 years of age or older. Pearl also has numerous other FDA clearances, totaling 26, for its Second Opinion® platform, covering 2D and 3D dental radiologic image analysis, including panoramic radiographs, bone level analysis, and detection of periapical radiolucencies and impacted third molars.

Integrations
EHR Not specified
Specialties Dentistry

What the Web Says

Pearl's Second Opinionu00ae CS is an AI-powered radiographic interpretation tool primarily used in dentistry to assist practitioners in diagnosing various conditions. It analyzes 2D X-rays to highlight potential areas of concern like caries, calculus, bone loss, and periapical radiolucencies. The platform aims to improve diagnostic accuracy, enhance patient communication, and streamline dental workflows. While the tool is generally well-received for its accuracy and user-friendly interface, some users note limitations such as its current inability to read 3D X-rays and potential server strain for large practices. For medical second opinions, general online services, not specific to Pearl's Second Opinion CS, are valued for providing expert reviews of medical records and offering alternative treatment plans, especially for complex or severe conditions, though direct interaction with specialists may be limited.

Overall: Positive

Strengths

  • Very accurate overall, rarely over-diagnoses.
  • User-friendly interface designed for patient communication.
  • Customizable AI detection display for various dental conditions.
  • HIPAA-compliant features for patient privacy.
  • Helps increase patient understanding and trust in diagnoses.
  • Integrates with existing imaging software for a streamlined workflow.

Limitations

  • Currently limited to 2D X-rays, cannot read CBCTs (3D X-rays are under development for 2025).
  • Cannot manually import images; relies on software integration.
  • Automatic image uploading can be heavy on servers for large practices.
  • Potential learning curve for staff to incorporate into daily routines.
  • Possible over-reliance on AI detections if not used judiciously.
  • Ongoing costs for licensing and updates.

Based on reviews from: Reddit, Dental Economics, Dentistry.co.uk, FeaturedCustomers

Last updated: 2026-07-20

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Videos

Product demos, reviews, and walkthroughs for Second Opinion® CS.

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Frequently Asked Questions

Second Opinionu00ae CS is designed to assist in the detection of common pathologies and conditions in dental X-rays, including caries (decay), calculus, periapical radiolucencies, and discrepancies at the margins of existing restorations. It also identifies crowns, fillings, root canals, bridges, and implants, with specialized versions detecting impacted third molars in panoramic images and clinically relevant anatomy in CBCT scans.
Second Opinionu00ae is the first chairside dental AI software with global regulatory clearances, including FDA clearance as a Class II Medical Image Analyzer, indicating it's an aid for dental professionals as a 'second reader'. While not a HIPAA 'covered entity,' Pearl states it adopts strict HIPAA Rules for Protected Health Information (PHI) and includes features like a PHI button to anonymize patient names for privacy.
Alternatives in the dental AI market include solutions like Overjet Dental Caries Assist, Denti.AI Detect, Diagnocat, and Velmeni. Second Opinionu00ae differentiates itself by being the first and only chairside dental AI with global regulatory clearances for detecting numerous conditions, offering the widest array of clinical detection capabilities, and integrating natively with major dental imaging platforms like Carestream Dental's CS Imaging for a seamless workflow.
Second Opinionu00ae operates on a subscription-based model, offering flexible monthly subscriptions and volume-based pricing to accommodate practices of different sizes. This typically includes a one-off setup fee and covers image integration, team training, and ongoing support.
Second Opinionu00ae is a computer-aided detection (CADe) tool intended to assist, not replace, a human diagnosis, and users should critically evaluate its suggestions. Its primary hazards include potential false positives and false negatives, and it does not predict lesion depth or severity. Currently, its core 2D analysis relies on consistent image capture and seamless syncing from existing imaging software, without a manual upload option.
Second Opinionu00ae CS is designed for seamless integration, particularly with Carestream Dental's CS Imaging platform, allowing real-time AI annotations directly within the software where images are captured and stored. It also integrates with many other major dental software platforms like Planet DDS, Patterson Dental, Romexis, and Henry Schein One, aiming to avoid workflow disruptions.
The learning curve for Second Opinionu00ae is described as minimal or not steep, with remote overnight installation often making it ready for use the next morning. Its intuitive interface is designed for simplicity and efficiency, and comprehensive support, including a dedicated Customer Success Manager, is provided for onboarding and ongoing assistance.

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Suggest an Edit → | Last Verified: 2026-04-18 | First Added: 2026-04-18

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