Products

FFRangio
CathWorks
Cardiology AI
FFRangio by CathWorks is an AI-powered, non-invasive system that uses routine angiograms to provide comprehensive physiological assessment of coronary artery disease, eliminating the need for invasive pressure wires and optimizing PCI decisions.

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About CathWorks

CathWorks is a medical technology company that leverages artificial intelligence (AI) and advanced computational science to transform the diagnosis and treatment of cardiovascular disease. Their flagship product, the FFRangio System, provides physicians with objective, wire-free fractional flow reserve (FFR) guidance derived from routine angiograms. This system eliminates the need for invasive pressure wires and drug-induced hyperemia traditionally required for FFR measurements, offering a quicker and more practical solution for assessing coronary artery disease (CAD) during catheterization procedures.

For physicians, the FFRangio System aims to optimize percutaneous coronary intervention (PCI) therapy decisions by providing comprehensive physiological information and color-coded 3D renderings of blood flow in the coronary arteries. This allows for more accurate treatment planning, including determining the necessity of a stent. The technology is designed to integrate seamlessly into existing cath lab workflows, enhancing efficiency and potentially improving patient outcomes by enabling evidence-based decision-making.

Focus Areas

Coronary Artery Disease (CAD) diagnosis and treatment Fractional Flow Reserve (FFR) assessment AI in cardiology computational science in healthcare medical imaging analysis interventional cardiology digital health

Business Intelligence

TechnologyAI and advanced computational science platform that transforms routine angiogram images into 3D models of coronary arteries to provide FFRangio values. It leverages a resistance-based computational approach.

What Physicians Need to Know

Coronary Artery Disease (CAD) Diagnosis & Treatment
CathWorks' FFRangio® System provides a quick and reliable intraprocedural physiological assessment for the entire coronary tree, aiding in the diagnosis and treatment planning of CAD. It helps differentiate functional patterns of CAD to target the most important segments for treatment.
Fractional Flow Reserve (FFR) Assessment
The FFRangio® System offers a non-invasive, wire-free, and drug-free approach to obtain FFR values from routine angiograms. It provides real-time FFRangio values at every point on the coronary tree and a simulated pullback curve.
AI in Cardiology & Computational Science in Healthcare
CathWorks combines AI and advanced computational science to transform 2D angiograms into a 3D volumetric model of the coronary tree. This technology analyzes blood flow resistance along each segment to calculate FFRangio values.
Medical Imaging Analysis
The system analyzes routine 2D angiograms, taken 30° apart, to create an accurate 3D model of the coronary anatomy. This allows for detailed analysis of every branch and bifurcation.
Interventional Cardiology
FFRangio streamlines procedural workflow in the cath lab, aiding interventional cardiologists in optimizing clinical decision-making. It includes tools for non-invasive lesion measurements and evaluating lesion impact.
Digital Health
CathWorks is a leader in coronary digital health innovations, providing objective, wire-free physiological information from routine angiograms. The system seamlessly integrates with cath lab equipment and PACS.
Physician Tip

For physicians, CathWorks' FFRangio® System offers several key advantages. It provides comprehensive, real-time physiological assessment of the entire coronary tree without the need for invasive pressure wires or hyperemic drugs, reducing patient risk and radiation exposure. The AI-powered analysis and 3D modeling optimize clinical decision-making by offering detailed insights into lesion significance and supporting PCI planning. This can lead to more precise and individualized treatment approaches, improved workflow efficiency, and potentially better patient outcomes. The system has demonstrated high diagnostic accuracy compared to wire-based FFR.

The CathWorks FFRangio® System is designed for seamless integration with existing cath lab infrastructure, including the boom and PACS (Picture Archiving and Communication System). It analyzes previously acquired angiography DICOM data, making it compatible with routine angiogram procedures. CathWorks was acquired by Medtronic in 2026, further expanding its reach and integration within interventional cardiology portfolios.

Products by CathWorks

1 product in the directory

FFRangio
CathWorks
Cardiology AI
FFRangio by CathWorks is an AI-powered, non-invasive system that uses routine angiograms to provide comprehensive physiological assessment of coronary artery disease, eliminating the need for invasive pressure wires and optimizing PCI decisions.

What the Web Says

CathWorks appears to be a company with a promising product, the FFRangio system, which is generally well-received by healthcare professionals for its potential to improve cardiac care. However, internal company reviews suggest a mixed to negative sentiment regarding management, work-life balance, and company culture, with some employees expressing concerns about leadership and high turnover.

Overall: Mixed

Strengths

  • Innovative product (FFRangio) with potential to improve patient outcomes
  • Strong clinical data supporting product efficacy
  • Positive impact on cardiac care procedures
  • Opportunity to work with cutting-edge technology
  • Dedicated and passionate colleagues (product-focused)
  • Good benefits package (mentioned in some employer reviews)

Limitations

  • Concerns about management and leadership decisions
  • Issues with work-life balance and long hours
  • High employee turnover reported by some
  • Lack of clear communication from upper management
  • Internal culture issues and perceived micromanagement
  • Rapid growth leading to organizational challenges

Based on reviews from: Glassdoor, Reddit (healthcare professional discussions), Healthcare IT review sites (general industry sentiment), Clinical trial publications/presentations

Last updated: 2026-10-23

Videos

News, demos, and interviews about CathWorks.

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Press & Coverage

MedTech Dive
Medtronic closes $585M purchase of CathWorks
Medtronic announced the completion of its acquisition of CathWorks for $585 million, with potential undisclosed earn-out payments. This acquisition follows a 2022 strategic partnership and aims to strengthen Medtronic's cardiovascular portfolio.
2026-04
CathWorks
Landmark ALL-RISE® Trial Results Presented at ACC.26: CathWorks FFRangio Demonstrates Similar Clinical Outcomes to Invasive Wire-based Physiology Assessment
Results from the ALL-RISE trial, presented at ACC.26, showed that CathWorks FFRangio demonstrated similar clinical outcomes to invasive wire-based physiology assessment, with improved resource utilization and reduced procedure time.
2026-03
Cardiovascular Business
Medtronic to acquire AI-enabled FFR specialists CathWorks for up to $585M
Medtronic announced its intent to acquire CathWorks for up to $585 million, highlighting CathWorks' FFRangio technology which uses AI to obtain fractional flow reserve measurements from X-ray images, aiming to eliminate the need for invasive pressure wires.
2026-02
CathWorks
PROVISION Study Which Met Its Primary Endpoint Now Demonstrates Similar Clinical Outcomes for FFRangio and FFR
The PROVISION Study, a Japanese prospective randomized controlled trial, demonstrated similar one-year MACE rates for FFRangio-guided treatment compared to invasive wire-based FFR guidance, with economic and resource utilization advantages for FFRangio.
2025-05
CathWorks
CathWorks Announces the Completion of Enrollment for Landmark ALL-RISE Randomized Controlled Trial
CathWorks successfully completed enrollment for the ALL-RISE randomized controlled trial, a significant milestone evaluating the clinical and economic benefits of the FFRangio System in diagnosing and treating coronary artery disease.
2025-01
PR Newswire
CathWorks Announces EU MDR Approval, Prominent Presence at EuroPCR and Full Launch of Co-promotion
CathWorks announced that its FFRangio System is now approved under the European Union Medical Device Regulation 2017/745 (EU MDR), fulfilling the requirements for CE marking. This approval coincides with the full European launch of its co-promotion partnership with Medtronic.
2024-05
CathWorks
CathWorks Announces Co-Promotion Agreement With Medtronic, With Path Toward Acquisition
Medtronic entered a strategic partnership agreement with CathWorks, including a co-promotion agreement for the FFRangio System and a path toward acquisition. This collaboration aims to invest in innovative technologies for cardiovascular disease management.
2022-07
CathWorks
Fourth Generation CathWorks FFRangio® System Receives Regulatory Approval in Japan
CathWorks announced the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) approval of its fourth-generation FFRangio System. This approval, combined with the Medtronic partnership, is expected to expand its presence in Japan.
2022-10

Frequently Asked Questions

CathWorks' flagship product is the FFRangio System, which provides a non-invasive, AI-powered alternative to traditional wire-based FFR. It utilizes standard angiograms to generate a 3D reconstruction of the coronary arteries and calculate FFR values, aiming to streamline CAD diagnosis and treatment planning by reducing procedural time and risks associated with pressure wires.
CathWorks' FFRangio System employs advanced computational fluid dynamics and machine learning algorithms to analyze angiographic images. The company validates its technology through extensive clinical trials and peer-reviewed publications, demonstrating high correlation with traditional FFR measurements and aiming for robust diagnostic accuracy in interventional cardiology.
CathWorks understands the critical importance of data security and compliance in digital health. The FFRangio System is designed with robust cybersecurity measures and adheres to relevant healthcare regulations, such as HIPAA, to protect patient data and ensure secure integration into hospital IT infrastructures.
While specific pricing details are typically discussed directly with interested institutions, CathWorks generally offers a value-based model that considers the clinical and economic benefits of the FFRangio System. They provide comprehensive support, including on-site training for physicians and staff, ongoing technical assistance, and clinical education to ensure optimal system utilization.
CathWorks actively seeks strategic partnerships with leading medical device companies and healthcare providers to expand its market reach and integrate its technology more broadly. The company has demonstrated strong financial backing and a clear growth trajectory, positioning itself as a stable and innovative player in the AI-driven cardiology space.

Investors

Who's funded CathWorks.

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