Products

VELYS Hip Navigation
DePuy Synthes (Johnson & Johnson)
Clinical Decision Support & Reference
VELYS™ Hip Navigation with AI Assistance is a next-generation software solution that automates image interpretation and landmark identification to deliver real-time, patient-specific insights on leg length, offset, and cup position during total hip arthroplasty.

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About DePuy Synthes (Johnson & Johnson)

DePuy Synthes, an orthopaedics company of Johnson & Johnson, offers a comprehensive portfolio of orthopaedic and neurosurgery products and services. Their solutions are designed to help heal and restore movement for millions of patients worldwide. The company’s offerings span various specialties, including joint reconstruction, trauma, craniomaxillofacial surgery, spinal surgery, and sports medicine. DePuy Synthes emphasizes a commitment to quality and innovation, aiming to simplify patient mobility.

For physicians, DePuy Synthes provides a wide array of products and technologies for surgical fixation and orthopedic procedures. These include implants and biomaterials for reconstructing damaged or diseased joints, repairing traumatic skeletal injuries, facilitating spinal fusion, and correcting spinal deformities. The company also supports the medical community through educational grants and fellowships for physicians in training, collaborating with institutions and third-party foundations to advance orthopaedic education and patient care.

Johnson & Johnson announced in October 2025 its intent to separate its Orthopaedics business, which operates as DePuy Synthes, into a standalone public company. This strategic move aims to allow both entities to thrive with a more concentrated strategic and operational focus, with the standalone DePuy Synthes positioned to be the largest pure-play orthopedics company globally.

Focus Areas

joint reconstruction trauma craniomaxillofacial spinal surgery sports medicine digital surgery orthopedic education robotic-assisted surgery medical devices biomaterials

Business Intelligence

TechnologyVELYS™ Digital Surgery portfolio (includes VELYS™ Hip Navigation with AI Assistance, VELYS™ Robotic-Assisted Knee Solutions, VELYS™ Spine), AI-powered image interpretation, machine learning models, cloud-native (implied by digital solutions and data-driven approach)

What Physicians Need to Know

Joint Reconstruction
DePuy Synthes offers a comprehensive portfolio for joint reconstruction, including hip, knee, and shoulder solutions. They are advancing with technologies like the VELYSu2122 Robotic-Assisted Solution for total knee arthroplasty, which is CT-free and aims for precise implant placement and personalized care. They are also developing radiofrequency miniature tracker technology for joint reconstruction to improve navigation and robotic applications by eliminating line-of-sight dependency.
Trauma & Extremities
The company provides extensive solutions for trauma care, including devices and systems for fracture healing and reconstruction. Key innovations include the VOLTu2122 Proximal Humerus Plating System and the MAXFRAME AUTOSTRUTu2122 Multi-Axial Correction System for deformity correction. They also offer unique solutions like ETN PROtect, an antibiotic-coated tibial nail, and the RIA 2 reaming system for autograft extraction.
Craniomaxillofacial (CMF)
DePuy Synthes offers a comprehensive portfolio for craniomaxillofacial conditions and injuries, focusing on personalized patient solutions. This includes the MatrixMIDFACEu2122 Plating System for trauma reconstruction and TRUMATCHu2122 CMF Personalized Solutions, which utilize 3D-printed titanium implants and surgical guides based on patient CT scans for orthognathic surgery and other craniofacial indications.
Spinal Surgery
DePuy Synthes provides a range of products for spinal surgery, addressing various spinal disorders and injuries. Recent advancements include the TriALTISu2122 Spine System, a next-generation posterior thoracolumbar pedicle screw system designed for integration with enabling technology and navigation. They have also launched the VELYSu2122 Active Robotic-Assisted System (VELYSu2122 SPINE), a dual-use robotics and standalone navigation platform for spinal fusion procedures.
Sports Medicine
Their sports medicine portfolio offers solutions for soft tissue pathologies of the shoulder, knee, hip, and small joints. This includes instruments and implants for ACL and meniscal repair, as well as arthroscopic equipment solutions.
Biomaterials
DePuy Synthes is a significant player in biomaterials, particularly for orthopedic and neurosurgical solutions. They focus on advanced biomaterials in orthopedic implants to achieve higher biocompatibility, strength, and durability, aiming to reduce complications and accelerate patient recovery.
Neurological Solutions
While specific details on neurological solutions are less prominent in recent highlights, DePuy Synthes is recognized for its contributions to neurosurgical solutions through biomaterials and has historically offered neurological products.
Power Tools
DePuy Synthes offers power tools designed for ergonomics, reliability, and efficiency across various procedures. The UNIUMu2122 System is a notable addition, providing a single platform for trauma, sports medicine, spine, and cardiothoracic surgery with modular handpieces and a high-capacity Li-Ion battery.
Digital Surgery & Enabling Technologies
DePuy Synthes is heavily invested in digital surgery through its VELYSu2122 Digital Surgery platform, which aims to provide connected solutions and data insights before, during, and after surgery. This includes robotic-assisted solutions, navigation systems (like VELYSu2122 Hip Navigation), and personalized surgical planning tools (TRUMATCHu2122 Personalized Solutions).
Physician Tip

DePuy Synthes emphasizes a 'beyond the implant' approach, focusing on integrated solutions that optimize processes, provide patient-specific information, and improve overall surgical experiences. Physicians can leverage their extensive educational resources through the Johnson & Johnson Institute to enhance their skills. The company's focus on digital surgery, robotics, and personalized solutions aims to improve precision, streamline workflows, and enhance patient outcomes. Their commitment to simplifying minimally invasive surgery with differentiated technologies like the VIPER PRIMEu2122 System and CONCORDEu00ae Clear MIS Discectomy Tool can lead to reduced procedural time and improved reproducibility.

DePuy Synthes is actively integrating advanced technologies through collaborations and acquisitions. They have partnered with the AO Foundation for product and surgical innovation and with Brainlab for digital surgery technologies, pre-operative planning, visualization, navigation, and robotics in spine. Their VELYSu2122 Digital Surgery platform is designed to connect various technologies pre-, intra-, and post-operatively. Recent agreements, such as the acquisition of Gemtrack technology, highlight their push for integrated image-guided and robotic-assisted joint surgery.

Products by DePuy Synthes (Johnson & Johnson)

1 product in the directory

VELYS Hip Navigation
DePuy Synthes (Johnson & Johnson)
Clinical Decision Support & Reference
VELYS™ Hip Navigation with AI Assistance is a next-generation software solution that automates image interpretation and landmark identification to deliver real-time, patient-specific insights on leg length, offset, and cup position during total hip arthroplasty.

What the Web Says

DePuy Synthes, a Johnson & Johnson company, is a major player in orthopedic and neurosurgical medical devices. Employee reviews indicate a generally positive work environment with good pay and benefits, although some roles, particularly in sales, are noted for poor work-life balance and high stress. Product-wise, DePuy Synthes offers a comprehensive portfolio, but has faced challenges with product recalls, notably the ASR hip implant systems, and some critics suggest a lag in innovation compared to competitors in certain areas.

Overall: Mixed

Strengths

  • Good pay and benefits for many employees.
  • Positive work environment and culture reported by many employees.
  • Interesting and rewarding work, particularly in engineering and product development.
  • Strong portfolio in trauma and capable joints portfolio.
  • Opportunities for learning and professional growth.
  • Commitment to diversity and inclusion (based on InHerSight scores for women).

Limitations

  • Poor work-life balance and high stress in some roles, especially trauma sales.
  • Concerns about job security and pensions due to the upcoming spin-off from Johnson & Johnson.
  • Perceived lack of innovation and underinvestment in R&D in some areas, lagging behind competitors in new technologies like robotics and 3D printing.
  • History of product recalls, such as the ASR hip implants and Attune knee implants, leading to lawsuits and reputational damage.
  • Some employees feel that the company does not uphold its core values.
  • Challenges with becoming a direct hire for contractors, leading to lower pay.

Based on reviews from: InHerSight, Comparably, Indeed, Which Medical Device, Reddit, DrugNews, Becker's Spine Review, Orthopedic Design & Technology, OpenLM, Trustpilot

Last updated: 2026-09-19

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Press & Coverage

MedTech Dive
J&J's $21B Synthes Bet Could End With $20B Sale to Apollo Global
Apollo Global Management is reportedly in talks to acquire Johnson & Johnson's DePuy Synthes orthopedics unit for $20 billion. This potential sale follows J&J's earlier announcement to spin out the orthopedics business to focus on higher-growth areas.
2026-09
MedTech Dive
J&J's DePuy Synthes inks deal to buy orthopedic surgery tech
DePuy Synthes, Johnson & Johnson's orthopedics business, has agreed to acquire technology for real-time tracking during surgical procedures from French medtech company MinMaxMedical. This technology, called Gemtrack, uses radiofrequency tracking as an alternative to infrared camera systems.
2026-05
J&J MedTech
DePuy Synthes Acquires Expanding Innovationsu2122
DePuy Synthes announced the acquisition of Expanding Innovations, Inc., a company specializing in expandable implant technology for spine surgery. This acquisition aims to strengthen DePuy Synthes' Spine portfolio and expand its presence in the growing expandable interbody cage market.
2026-07
J&J MedTech
DePuy Synthes Launches VELYSu2122 Hip Navigation with AI to Support Intraoperative Consistency and Efficiency in Total Hip Arthroplasty
DePuy Synthes launched VELYSu2122 Hip Navigation with AI, a new system designed to enhance intraoperative consistency and efficiency during total hip arthroplasty procedures. This launch is part of their ongoing efforts to advance digital orthopaedics.
2026-06
J&J MedTech
DePuy Synthes Enters Exclusive U.S., Canada and Australia Distribution Agreement for CGBIO's NOVOSIS
DePuy Synthes has entered into an exclusive distribution agreement with CGBIO for NOVOSIS, an advanced bone graft substitute. This agreement covers the United States, Canada, and Australia, strengthening DePuy Synthes' orthopaedic portfolio.
2026-05
Simply Wall St News
Johnson & Johnson (JNJ) Weighs DePuy Synthes Exit In MedTech Portfolio Reset
Johnson & Johnson is reportedly considering selling its DePuy Synthes orthopedics unit to Apollo Global Management, a move that would significantly reshape J&J's medical devices portfolio. This potential divestiture aligns with J&J's strategy to focus on higher-growth areas like cardiovascular technology and robotics.
2026-09
Johnson & Johnson
Johnson & Johnson announces intent to separate its Orthopaedics business
Johnson & Johnson announced its intention to separate its Orthopaedics business, DePuy Synthes, into a standalone company. This strategic move aims to enhance the focus and operational efficiency of both entities and drive value for stakeholders.
2025-10
PR Newswire
DePuy Synthes Receives 510(k) FDA Clearance of the VELYSu2122 Robotic-Assisted Solution for Use in Unicompartmental Knee Arthroplasty Procedures
DePuy Synthes received 510(k) FDA clearance for its VELYSu2122 Robotic-Assisted Solution for use in unicompartmental knee arthroplasty procedures. This clearance expands the application of their robotic-assisted technology in orthopedic surgery.
2024-06

Frequently Asked Questions

DePuy Synthes offers a comprehensive portfolio in joint reconstruction, including solutions for hip, knee, and shoulder arthroplasty. Key differentiators often include proprietary material science, advanced bearing surfaces, and instrumentations designed for surgical efficiency and patient-specific outcomes. Specific product lines like ATTUNEu00ae Knee System and CORAILu00ae Hip System are frequently highlighted for their clinical performance and longevity.
DePuy Synthes maintains robust quality management systems and regulatory affairs teams to ensure compliance with global medical device regulations, such as FDA, MDR, and other regional requirements. They provide extensive documentation, training, and support to healthcare providers regarding product usage, adverse event reporting, and recall procedures to help them meet their own compliance obligations.
DePuy Synthes' pricing for trauma and spine products is typically structured based on volume, contract terms, and product complexity. For large hospital systems, they often offer bundled pricing, volume discounts, and value-based programs designed to optimize costs while maintaining quality. Specific initiatives may include consignment programs or inventory management solutions.
DePuy Synthes provides extensive clinical and technical support for their power tools and neurological solutions. This includes pre-operative planning assistance, on-site surgical support by product specialists, and post-operative follow-up and troubleshooting. They also offer educational programs, workshops, and online resources to ensure optimal product utilization and surgeon proficiency.
DePuy Synthes' innovation strategy in sports medicine and biomaterials focuses on addressing unmet clinical needs through research and development, often leveraging advanced materials and minimally invasive techniques. They actively collaborate with leading surgeons and academic institutions through surgeon advisory boards, clinical trials, and direct feedback mechanisms to inform and guide new product development from concept to commercialization.
As a Johnson & Johnson company, DePuy Synthes benefits from the financial stability and extensive resources of one of the world's largest healthcare corporations. This ensures long-term product availability, sustained investment in research and development, and a robust supply chain. Their position within J&J provides a strong foundation for continued innovation and market leadership.
DePuy Synthes actively pursues strategic partnerships with healthcare technology companies, startups, and academic institutions to drive innovation in surgical techniques and improve patient outcomes. These collaborations often focus on areas like digital surgery, artificial intelligence, robotics, and advanced materials research, aiming to integrate cutting-edge technologies into their product offerings and surgical workflows.

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